Respiratory virus detection and co-infection in children and adults in a large Australian hospital in 2009–2015

Journal of Paediatrics and Child Health

Volumn 54, Issue 12, 2018, Pages 1321-1328

  Ching, Natasha S ^a,b   Kotsanas, Despina ^a   Easton, Mee L ^c   Francis, Michelle J ^a   Korman, Tony M ^a,b   Buttery, Jim P ^a,b,c  

^a SOUTHERN HEALTH   (Australia)

^b MONASH UNIVERSITY   (Australia)

^c MURDOCH CHILDREN'S RESEARCH INSTITUTE   (Australia)

Author keywords

co infection; paediatric; polymerase chain reaction; respiratory; viral

Indexed keywords

ADENOVIRIDAE; ADULT; ARTICLE; AUSTRALIA; CHILD; CLINICAL PROTOCOL; CONTROLLED STUDY; COST EFFECTIVENESS ANALYSIS; HUMAN; MAJOR CLINICAL STUDY; MIXED INFECTION; MOLECULAR DYNAMICS; MORTALITY; MULTIPLEX POLYMERASE CHAIN REACTION; OBSERVATIONAL STUDY; PRIORITY JOURNAL; RESPIRATORY VIRUS; RETROSPECTIVE STUDY; SYMPTOMATOLOGY; VIRUS DETECTION; VIRUS INFECTION; ADOLESCENT; HOSPITAL; ISOLATION AND PURIFICATION; PREVALENCE; RESPIRATORY TRACT INFECTION; VICTORIA; VIRUS; YOUNG ADULT;

ADOLESCENT; COINFECTION; HOSPITALS, PEDIATRIC; HUMANS; MULTIPLEX POLYMERASE CHAIN REACTION; PREVALENCE; RESPIRATORY TRACT INFECTIONS; RETROSPECTIVE STUDIES; VICTORIA; VIRUSES; YOUNG ADULT;

EID: 85057593581     PISSN: 10344810     EISSN: 14401754     Source Type: Journal    
DOI: 10.1111/jpc.14076     Document Type: Article

References (32)

1. Shay D, Holman R, Newman R, Liu L, Stout J, Anderson L. Bronchiolitis-associated hospitalizations among US children, 1980–1996. JAMA 1999; 282: 1440–6.
2. Bicer S, Giray T, Col D et al. Virological and clinical characterizations of respiratory infections in hospitalized children. Ital. J. Pediatr. 2013; 39: 22.
3. Tsolia MN, Psarras S, Bossios A et al. Etiology of community-acquired pneumonia in hospitalized school-age children: Evidence for high prevalence of viral infections. Clin. Infect. Dis. 2004; 39: 681–6.
4. Sangil A, Calbo E, Robles A et al. Aetiology of community-acquired pneumonia among adults in an H1N1 pandemic year: The role of respiratory viruses. Eur. J. Clin. Microbiol. Infect. Dis. 2012; 31: 2765–72.
5. Ishiguro T, Takayanagi N, Yamaguchi S et al. Etiology and factors contributing to the severity and mortality of community-acquired pneumonia. Intern. Med. 2013; 52: 317–24.
6. Mermond S, Berlioz-Arthaud A, Estivals M, Baumann F, Levenes H, Martin PMV. Aetiology of community-acquired pneumonia in hospitalized adult patients in New Caledonia. Trop. Med. Int. Health 2010; 15: 1517–24.
7. Munywoki PK, Hamid F, Mutunga M, Welch S, Cane P, Nokes DJ. Improved detection of respiratory viruses in pediatric outpatients with acute respiratory illness by real-time PCR using nasopharyngeal flocked swabs. J. Clin. Microbiol. 2011; 49: 3365–7.
8. Mahony JB. Detection of respiratory viruses by molecular methods. Clin. Microbiol. Rev. 2008; 21: 716–47.
9. Jartti T, Söderlund-Venermo M, Hedman K, Ruuskanen O, Mäkelä MJ. New molecular virus detection methods and their clinical value in lower respiratory tract infections in children. Paediatr. Respir. Rev. 2013; 14: 38–45.
10. de Vries M, Deijs M, Canuti M et al. A sensitive assay for virus discovery in respiratory clinical samples. PLoS One 2011; 6: e16118.
11. Chen Y, Cui D, Zheng S et al. Simultaneous detection of influenza A, influenza B, and respiratory syncytial viruses and subtyping of influenza A H3N2 virus and H1N1 (2009) virus by multiplex real-time PCR. J. Clin. Microbiol. 2011; 49: 1653–6.
12. Szewczuk E, Thapa K, Anninos T et al. Rapid semi-automated quantitative multiplex tandem PCR (MT-PCR) assays for the differential diagnosis of influenza-like illness. BMC Infect. Dis. 2010; 10: 113.
13. Gill PJ, Richardson SE, Ostrow O, Friedman JN. Testing for respiratory viruses in children: To swab or not to swab. JAMA Pediatr. 2017; 171: 798–804.
14. Sung RYT, Chan PKS, Tsen T et al. Identification of viral and atypical bacterial pathogens in children hospitalized with acute respiratory infections in Hong Kong by multiplex PCR assays. J. Med. Virol. 2009; 81: 153–9.
15. Pierangeli A, Gentile M, Di Marco P et al. Detection and typing by molecular techniques of respiratory viruses in children hospitalized for acute respiratory infection in Rome, Italy. J. Med. Virol. 2007; 79: 463–8.
16. Blaschke AJ, Allison MA, Meyers L et al. Non-invasive sample collection for respiratory virus testing by multiplex PCR. J. Clin. Virol. 2011; 52: 210–4.
17. Verani JR, McCracken J, Arvelo W et al. Surveillance for hospitalized acute respiratory infection in Guatemala. PLoS One 2013; 8: e83600.
18. Drieghe S, Ryckaert I, Beuselinck K, Lagrou K, Padalko E. Epidemiology of respiratory viruses in bronchoalveolar lavage samples in a tertiary hospital. J. Clin. Virol. 2014; 59: 208–11.
19. Kim JH, Moon BJ, Gong C-H, Kim NH, Jang YJ. Detection of respiratory viruses in adult patients with perennial allergic rhinitis. Ann. Allergy Asthma Immunol. 2013; 111: 508–11.
20. Fuller DG, Davie G, Lamb D, Carlin JB, Curtis N. Analysis of respiratory viral coinfection and cytomegalovirus coisolation in pediatric inpatients. Pediatr. Infect. Dis. J. 2005; 24: 195–200.
21. Hatipoglu N, Somer A, Badur S et al. Viral etiology in hospitalized children with acute lower respiratory tract infection. Turk. J. Pediatr. 2011; 53: 508–16.
22. Khamis FA, Al-Kobaisi MF, Al-Areimi WS, Al-Kindi H, Al-Zakwani I. Epidemiology of respiratory virus infections among infants and young children admitted to hospital in Oman. J. Med. Virol. 2012; 84: 1323–9.
23. Pretorius MA, Madhi SA, Cohen C et al. Respiratory viral coinfections identified by a 10-plex real-time reverse-transcription polymerase chain reaction assay in patients hospitalized with severe acute respiratory illness – South Africa, 2009–2010. J. Infect. Dis. 2012; 206 (Suppl. 1): S159–65.
24. Buecher C, Mardy S, Wang W et al. Use of a multiplex PCR/RT-PCR approach to assess the viral causes of influenza-like illnesses in Cambodia during three consecutive dry seasons. J. Med. Virol. 2010; 82: 1762–72.
25. Cho GS, Moon BJ, Lee BJ et al. High rates of detection of respiratory viruses in the nasal washes and mucosae of patients with chronic rhinosinusitis. J. Clin. Microbiol. 2013; 51: 979–84.
26. Peghin M, Hirsch HH, Len Ó et al. Epidemiology and immediate indirect effects of respiratory viruses in lung transplant recipients: A 5-year prospective study. Am. J. Transplant. 2017; 17: 1304–12.
27. Lu X, Schneider E, Jain S et al. Rhinovirus viremia in patients hospitalized with community-acquired pneumonia. J. Infect. Dis. 2017; 216: 1104–11.
28. Njouom R, Yekwa EL, Cappy P, Vabret A, Boisier P, Rousset D. Viral etiology of influenza-like illnesses in Cameroon, January–December 2009. J. Infect. Dis. 2012; 206 (Suppl. 1): S29–35.
29. Jain S, Williams DJ, Arnold SR et al. Community-acquired pneumonia requiring hospitalization among U.S. children. N. Engl. J. Med. 2015; 372: 835–45.
30. Zhang D, He Z, Xu L et al. Epidemiology characteristics of respiratory viruses found in children and adults with respiratory tract infections in southern China. Int. J. Infect. Dis. 2014; 25: 159–64.
31. Chonmaitree T, Alvarez-Fernandez P, Jennings K et al. Symptomatic and asymptomatic respiratory viral infections in the first year of life: Association with acute otitis media development. Clin. Infect. Dis. 2015; 60: 1–9.
32. Rhedin S, Lindstrand A, Rotzen-Ostlund M et al. Clinical utility of PCR for common viruses in acute respiratory illness. Pediatrics 2014; 133: e538–45.