Underuse of Oral Anticoagulants in Patients With Ischemic Stroke and Atrial Fibrillation in China

American Journal of Cardiology

Volumn 122, Issue 12, 2018, Pages 2055-2061

  Guo, Jian ^a   Guan, Tianjia ^a   Fan, Siyuan ^b   Chao, Baohua ^c   Wang, Longde ^d   Liu, Yuanli ^a  

^a PEKING UNION MEDICAL COLLEGE   (China)

^b PEKING UNION MEDICAL COLLEGE HOSPITAL   (China)

^c Ministry of Science and Technology of the PR China   (China)

^d PEKING UNIVERSITY HEALTH SCIENCE CENTER   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ANTICOAGULANT AGENT; DABIGATRAN; DIPYRIDAMOLE; RIVAROXABAN; WARFARIN;

ADULT; AGED; ARTICLE; ATRIAL FIBRILLATION; BODY MASS; BRAIN ISCHEMIA; CLINICAL PRACTICE; CONTROLLED STUDY; DRUG EFFICACY; DRUG SAFETY; DYSLIPIDEMIA; ELECTROCARDIOGRAPHY; FEMALE; HUMAN; LOGISTIC REGRESSION ANALYSIS; MAJOR CLINICAL STUDY; MALE; MIDDLE AGED; PHYSICAL ACTIVITY; PHYSICAL EXAMINATION; PRIORITY JOURNAL; RANKIN SCALE; RISK ASSESSMENT; RISK FACTOR; URBAN RURAL DIFFERENCE; VERY ELDERLY; CHINA; CLINICAL TRIAL; COMPLICATION; MULTICENTER STUDY; ODDS RATIO; ORAL DRUG ADMINISTRATION; PREVALENCE; PROTOCOL COMPLIANCE; REGISTER; RETROSPECTIVE STUDY; TREATMENT OUTCOME;

ADMINISTRATION, ORAL; ADULT; AGED; AGED, 80 AND OVER; ANTICOAGULANTS; ATRIAL FIBRILLATION; BRAIN ISCHEMIA; CHINA; FEMALE; GUIDELINE ADHERENCE; HUMANS; MALE; MIDDLE AGED; ODDS RATIO; PREVALENCE; REGISTRIES; RETROSPECTIVE STUDIES; RISK FACTORS; TREATMENT OUTCOME;

EID: 85056839769     PISSN: 00029149     EISSN: 18791913     Source Type: Journal    
DOI: 10.1016/j.amjcard.2018.08.057     Document Type: Article

References (30)

1. Guan, T, Ma, J, Li, M, Xue, T, Lan, Z, Guo, J, Shen, Y, Chao, B, Tian, G, Zhang, Q, Wang, L, Liu, Y, Rapid transitions in the epidemiology of stroke and its risk factors in China from 2002 to 2013. Neurology 89 (2017), 53–61.
2. Hankey, GJ., Stroke. Lancet 389 (2017), 641–654.
3. Kelly, PJ, Preventing the rise of atrial fibrillation-related stroke in populations. Circulation 130 (2014), 1221–1222.
4. Freedman, B, Potpara, TS, Lip, GYH, Stroke prevention in atrial fibrillation. Lancet 388 (2016), 806–817.
5. Ogilvie, IM, Newton, N, Welner, SA, Cowell, W, Lip, GY, Underuse of oral anticoagulants in atrial fibrillation: a systematic review. Am J Med, 123, 2010 638–645.e4.
6. Wang, C, Yang, Z, Wang, C, Wang, Y, Zhao, X, Liu, L, Wang, D, Li, H, Wang, Y, Significant underuse of warfarin in patients with nonvalvular atrial fibrillation: results from the China national stroke registry. J Stroke Cerebrovasc 23 (2014), 1157–1163.
7. Longde, W, Ling, Y, Yang, H, Yi, Z, Yongjun, W, Xunming, J, Qiumin, Q, Li, H, Yuming, X, Mei, L, Jiayi, S, Jing, L, Dong, Z, Fixed-dose combination treatment after stroke for secondary prevention in China: a national community-based study. Stroke 46 (2015), 1295–1300.
8. World Health Organization Task Force on Stroke and Other Cerebrovascular Disorders. Stroke–1989. Recommendations on stroke prevention, diagnosis, and therapy. Report of the WHO Task Force on Stroke and Other Cerebrovascular Disorders. Stroke 20 (1989), 1407–1431.
9. 2-VASc scores: the China National Stroke Registry. CNS Neurosci Ther 18 (2012), 988–993.
10. January, CT, Wann, LS, Alpert, JS, Calkins, H, Cigarroa, JE, Cleveland, JC, Conti, JB, Ellinor, PT, Ezekowitz, MD, Field, ME, Murray, KT, Sacco, RL, Stevenson, WG, Tchou, PJ, Tracy, CM, Yancy, CW, 2014 AHA/ACC/HRS guideline for the management of patients with atrial fibrillation: executive summary. J Am Coll Cardiol 64 (2014), 2246–2280.
11. Bruzzi, P, Green, SB, Byar, DP, Brinton, LA, Schairer, C, Estimating the population attributable risk for multiple risk factors using case-control data. Am J Epidemiol 122 (1985), 904–914.
12. Wang, YL, Wu, D, Nguyen-Huynh, MN, Zhou, Y, Wang, CX, Zhao, XQ, Liao, XL, Liu, LP, Wang, YJ, Prevention of Recurrences of Stroke Study in China Investigators. Antithrombotic management of ischaemic stroke and transient ischaemic attack in China: a consecutive cross-sectional survey. Clin Exp Pharmacol Physiol 37 (2010), 775–781.
13. Zhou, ZQ, Hu, DY, Chen, J, Zhang, RH, Li, KB, Zhao, XL, An epidemiological survey of atrial fibrillation in China. Chin J Intern Med 43 (2004), 491–494.
14. Yang, Y, Han, X, Chen, Y, Gao, L, Yin, X, Li, H, Qiu, J, Wang, Y, Zhou, Y, Xia, Y, Association between modifiable lifestyle and the prevalence of atrial fibrillation in a Chinese population: based on the cardiovascular health score. Clin Cardiol 40 (2017), 1061–1067.
15. Ministry of Health. Chinese Health Statistical Digest 2006. 2006.
16. Yang, X, Li, S, Zhao, X, Liu, L, Jiang, Y, Li, Z, Wang, Y, Wang, Y, Atrial fibrillation is not uncommon among patients with ischemic stroke and transient ischemic stroke in China. BMC Neurol, 17, 2017, 207.
17. Reading, SR, Go, AS, Fang, MC, Singer, DE, Liu, IA, Black, MH, Udaltsova, N, Reynolds, K, Anticoagulation and Risk Factors in Atrial Fibrillation–Cardiovascular Research Network, Investigators. Health literacy and awareness of atrial fibrillation. J Am Heart Assoc, 6, 2017, e005128.
18. Chien, KL, Su, TC, Hsu, HC, Chang, WT, Chen, PC, Chen, MF, Lee, YT, Atrial fibrillation prevalence, incidence and risk of stroke and all-cause death among Chinese. Int J Cardiol 139 (2010), 173–180.
19. Zullig, LL, Ramos, K, Bosworth, HB, Improving medication adherence in coronary heart disease. Curr Cardiol Rep, 19, 2017, 113.
20. Sjolander, M, Eriksson, M, Asplund, K, Norrving, B, Glader, EL, Socioeconomic inequalities in the prescription of oral anticoagulants in stroke patients with atrial fibrillation. Stroke 46 (2015), 2220–2225.
21. Komen, J, Forslund, T, Hjemdahl, P, Wettermark, B, Factors associated with antithrombotic treatment decisions for stroke prevention in atrial fibrillation in the Stockholm region after the introduction of NOACs. Eur J Clin Pharmacol 73 (2017), 1315–1322.
22. Sposato, LA, Cipriano, LE, Saposnik, G, Vargas, ER, Riccio, PM, Hachinski, V, Diagnosis of atrial fibrillation after stroke and transient ischaemic attack: a systematic review and meta-analysis. Lancet Neurol 14 (2015), 377–387.
23. The Lancet. Atrial fibrillation and stroke: unrecognised and undertreated. Lancet, 388, 2016, 731.
24. Nieuwlaat, R, Capucci, A, Lip, GY, Olsson, SB, Prins, MH, Nieman, FH, López-Sendón, J, Vardas, PE, Aliot, E, Santini, M, Crijns, HJ, Euro Heart Survey Investigators. Antithrombotic treatment in real-life atrial fibrillation patients: a report from the Euro Heart Survey on Atrial Fibrillation. Eur Heart J 27 (2006), 3018–3026.
25. Sen, S, Dahlberg, KW, Physician's fear of anticoagulant therapy in nonvalvular atrial fibrillation. Am J Med Sci 348 (2014), 513–521.
26. Tanislav, C, Milde, S, Schwartzkopff, S, Sieweke, N, Kramer, HH, Juenemann, M, Misselwitz, B, Kaps, M, Secondary stroke prevention in atrial fibrillation: a challenge in the clinical practice. BMC Neurol, 14, 2014, 195.
27. Li, W, Gu, H, Teo, KK, Bo, J, Wang, Y, Yang, J, Wang, X, Zhang, H, Sun, Y, Jia, X, He, X, Zhao, X, Cheng, X, Li, J, Rangarajan, S, Chen, C, Yusuf, S, Liu, L, PURE China Investigators. Hypertension prevalence, awareness, treatment, and control in 115 rural and urban communities involving 47 000 people from China. J Hypertens 34 (2016), 39–46.
28. Wang, L, Gao, P, Zhang, M, Huang, Z, Zhang, D, Deng, Q, Li, Y, Zhao, Z, Qin, X, Jin, D, Zhou, M, Tang, X, Hu, Y, Wang, L, Prevalence and ethnic pattern of diabetes and prediabetes in China in 2013. JAMA 317 (2017), 2515–2523.
29. Li, JH, Wang, LM, Mi, SQ, Zhang, M, Li, YC, Jiang, Y, Xu, Y, Dai, M, Wang, LH, Awareness rate, treatment rate and control rate of dyslipidemia in Chinese adults, 2010. Chin J Prev Med 46 (2012), 687–691.
30. Zhou, Z, Hu, D, An epidemiological study on the prevalence of atrial fibrillation in the Chinese population of Mainland China. J Epidemiol 18 (2008), 209–216.