Cardiac-Specific Deletion of Pyruvate Dehydrogenase Impairs Glucose Oxidation Rates and Induces Diastolic Dysfunction

Frontiers in Cardiovascular Medicine

Volumn 5, Issue , 2018, Pages

  Gopal, Keshav ^a,b   Almutairi, Malak ^a,b   Al Batran, Rami ^a,b   Eaton, Farah ^a,b   Gandhi, Manoj ^a,b   Ussher, John Reyes ^a,b  

^a UNIVERSITY OF ALBERTA   (Canada)

^b UNIVERSITY OF ALBERTA   (Canada)

Author keywords

cardiac function; diabetic cardiomyopathy; diastolic dysfunction; glucose oxidation; pyruvate dehydrogenase

Indexed keywords

INSULIN; PYRUVATE DEHYDROGENASE; TRIACYLGLYCEROL;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD SAMPLING; CONTROLLED STUDY; DIASTOLIC DYSFUNCTION; ENERGY METABOLISM; FATTY ACID BLOOD LEVEL; FATTY ACID LEVEL; GENE; GENE DELETION; GLUCOSE OXIDATION; HEART FUNCTION; HEART LEFT VENTRICLE EJECTION FRACTION; HEART OUTPUT; HEART PERFUSION; HEART VENTRICLE HYPERTROPHY; INSULIN BLOOD LEVEL; MALE; MOUSE; NONHUMAN; PDHA1 GENE; PHENOTYPE; SYSTOLIC DYSFUNCTION; TRANSTHORACIC ECHOCARDIOGRAPHY; TRIACYLGLYCEROL BLOOD LEVEL; WESTERN BLOTTING;

EID: 85055281305     PISSN: None     EISSN: 2297055X     Source Type: Journal    
DOI: 10.3389/fcvm.2018.00017     Document Type: Article

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