The effects of vitamin D supplementation on metabolic profiles and gene expression of insulin and lipid metabolism in infertile polycystic ovary syndrome candidates for in vitro fertilization

Reproductive Biology and Endocrinology

Volumn 16, Issue 1, 2018, Pages

  Dastorani, Majid ^a   Aghadavod, Esmat ^a   Mirhosseini, Naghmeh ^b   Foroozanfard, Fatemeh ^a   Zadeh Modarres, Shahrzad ^c   Amiri Siavashani, Mehrnush ^d   Asemi, Zatollah ^a  

^a KASHAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^b UNIVERSITY OF SASKATCHEWAN   (Canada)

^c SHAHID BEHESHTI UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^d SHAHID BEHESHTI UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

Cardio metabolic; Glycemic control; In vitro fertilization; Vitamin D supplementation

Indexed keywords

INSULIN; TRANSCRIPTOME; VITAMIN; VITAMIN D;

ADOLESCENT; ADULT; CONTROLLED STUDY; DIETARY SUPPLEMENT; DOUBLE BLIND PROCEDURE; DRUG EFFECT; FEMALE; FEMALE INFERTILITY; GENETICS; HUMAN; IN VITRO FERTILIZATION; IRAN; LIPID METABOLISM; METABOLISM; OVARY POLYCYSTIC DISEASE; PREGNANCY; RANDOMIZED CONTROLLED TRIAL; RETROSPECTIVE STUDY; VITAMIN D DEFICIENCY; YOUNG ADULT;

ADOLESCENT; ADULT; DIETARY SUPPLEMENTS; DOUBLE-BLIND METHOD; FEMALE; FERTILIZATION IN VITRO; HUMANS; INFERTILITY, FEMALE; INSULIN; IRAN; LIPID METABOLISM; POLYCYSTIC OVARY SYNDROME; PREGNANCY; RETROSPECTIVE STUDIES; TRANSCRIPTOME; VITAMIN D; VITAMIN D DEFICIENCY; VITAMINS; YOUNG ADULT;

EID: 85054466317     PISSN: None     EISSN: 14777827     Source Type: Journal    
DOI: 10.1186/s12958-018-0413-3     Document Type: Article

References (39)

1. Sheehan MT. Polycystic ovarian syndrome: diagnosis and management. Clin Med Res. 2004;2:13-27.
2. Fica S, Albu A, Constantin M, Dobri GA. Insulin resistance and fertility in polycystic ovary syndrome. J Med Life. 2008;1:415-22.
3. Ceelen M, van Weissenbruch MM, Roos JC, Vermeiden JP, van Leeuwen FE. Delemarre-van de Waal HA. Body composition in children and adolescents born after in vitro fertilization or spontaneous conception. J Clin Endocrinol Metab. 2007;92:3417-23.
4. Ceelen M, van Weissenbruch MM, Vermeiden JP, van Leeuwen FE. Delemarre-van de Waal HA. Cardiometabolic differences in children born after in vitro fertilization: follow-up study. J Clin Endocrinol Metab. 2008;93:1682-8.
5. Rexhaj E, Paoloni-Giacobino A, Rimoldi SF, Fuster DG, Anderegg M, Somm E, et al. Mice generated by in vitro fertilization exhibit vascular dysfunction and shortened life span. J Clin Invest. 2013;123:5052-60.
6. Scott KA, Yamazaki Y, Yamamoto M, Lin Y, Melhorn SJ, Krause EG, et al. Glucose parameters are altered in mouse offspring produced by assisted reproductive technologies and somatic cell nuclear transfer. Biol Reprod. 2010;83:220-7.
7. Vlaisavljevic V, Kovac V, Sajko MC. Impact of insulin resistance on the developmental potential of immature oocytes retrieved from human chorionic gonadotropin-primed women with polycystic ovary syndrome undergoing in vitro maturation. Fertil Steril. 2009;91:957-9.
8. Halloran BP, DeLuca HF. Effect of vitamin D deficiency on fertility and reproductive capacity in the female rat. J Nutr. 1980;110:1573-80.
9. Daftary GS, Taylor HS. Endocrine regulation of HOX genes. Endocr Rev. 2006;27:331-55.
10. Kinuta K, Tanaka H, Moriwake T, Aya K, Kato S, Seino Y. Vitamin D is an important factor in estrogen biosynthesis of both female and male gonads. Endocrinology. 2000;141:1317-24.
11. Johnson LE, DeLuca HF. Vitamin D receptor null mutant mice fed high levels of calcium are fertile. J Nutr. 2001;131:1787-91.
12. Wehr E, Pilz S, Schweighofer N, Giuliani A, Kopera D, Pieber TR, et al. Association of hypovitaminosis D with metabolic disturbances in polycystic ovary syndrome. Eur J Endocrinol. 2009;161:575-82.
13. Yildizhan R, Kurdoglu M, Adali E, Kolusari A, Yildizhan B, Sahin HG, et al. Serum 25-hydroxyvitamin D concentrations in obese and non-obese women with polycystic ovary syndrome. Arch Gynecol Obstet. 2009;280:559-63.
14. Turer CB, Lin H, Flores G. Prevalence of vitamin D deficiency among overweight and obese US children. Pediatrics. 2013;131:e152-61.
15. Zadeh-Vakili A, Ramezani Tehrani F, Daneshpour MS, Zarkesh M, Saadat N, Azizi F. Genetic polymorphism of vitamin D receptor gene affects the phenotype of PCOS. Gene. 2013;515:193-6.
16. Aleyasin A, Hosseini MA, Mahdavi A, Safdarian L, Fallahi P, Mohajeri MR, et al. Predictive value of the level of vitamin D in follicular fluid on the outcome of assisted reproductive technology. Eur J Obstet Gynecol Reprod Biol. 2011;159:132-7.
17. Anifandis GM, Dafopoulos K, Messini CI, Chalvatzas N, Liakos N, Pournaras S, et al. Prognostic value of follicular fluid 25-OH vitamin D and glucose levels in the IVF outcome. Reprod Biol Endocrinol. 2010;8:91.
18. Butts SF, Seifer DB, Koelper N, Senapati S, Sammel MD, Hoofnagle AN, et al. Vitamin D deficiency is associated with poor ovarian stimulation outcome in pcos but not unexplained infertility. J Clin Endocrinol Metab. 2018. https://doi.org/10.1210/jc.2018-00750.
19. He C, Lin Z, Robb SW, Ezeamama AE. Serum vitamin D levels and polycystic ovary syndrome: a systematic review and meta-analysis. Nutrients. 2015;7:4555-77.
20. Seyyed Abootorabi M, Ayremlou P, Behroozi-Lak T, Nourisaeidlou S. The effect of vitamin D supplementation on insulin resistance, visceral fat and adiponectin in vitamin D deficient women with polycystic ovary syndrome: a randomized placebo-controlled trial. Gynecol Endocrinol. 2018;34:489-94.
21. Xue Y, Xu P, Xue K, Duan X, Cao J, Luan T, et al. Effect of vitamin D on biochemical parameters in polycystic ovary syndrome women: a meta-analysis. Arch Gynecol Obstet. 2017;295:487-96.
22. Taylor PN, Davies JS. A review of the growing risk of vitamin D toxicity from inappropriate practice. Br J Clin Pharmacol. 2018;84:1121-7.
23. Rotterdam ESHRE/ASRM-Sponsored PCOS Consensus Workshop Group. Revised 2003 consensus on diagnostic criteria and long-term health risks related to polycystic ovary syndrome. Fertil Steril. 2004;81:19-25.
24. Pisprasert V, Ingram KH, Lopez-Davila MF, Munoz AJ, Garvey WT. Limitations in the use of indices using glucose and insulin levels to predict insulin sensitivity: impact of race and gender and superiority of the indices derived from oral glucose tolerance test in African Americans. Diabetes Care. 2013;36:845-53.
25. Dunkley PR, Jarvie PE, Robinson PJ. A rapid Percoll gradient procedure for preparation of synaptosomes. Nat Protoc. 2008;3:1718-28.
26. Maktabi M, Chamani M, Asemi Z. The effects of vitamin D supplementation on metabolic status of patients with polycystic ovary syndrome: a randomized, double-blind, placebo-controlled trial. Horm Metab Res. 2017;49:493-8.
27. Asemi Z, Foroozanfard F, Hashemi T, Bahmani F, Jamilian M, Esmaillzadeh A. Calcium plus vitamin D supplementation affects glucose metabolism and lipid concentrations in overweight and obese vitamin D deficient women with polycystic ovary syndrome. Clin Nutr. 2015;34:586-92.
28. Foroozanfard F, Jamilian M, Bahmani F, Talaee R, Talaee N, Hashemi T, et al. Calcium plus vitamin D supplementation influences biomarkers of inflammation and oxidative stress in overweight and vitamin D-deficient women with polycystic ovary syndrome: a randomized double-blind placebo-controlled clinical trial. Clin Endocrinol. 2015;83:888-94.
29. Gupta T, Rawat M, Gupta N, Arora S. Study of effect of vitamin D supplementation on the clinical, hormonal and metabolic profile of the PCOS women. J Obstet Gynaecol India. 2017;67:349-55.
30. Wehr E, Pieber TR, Obermayer-Pietsch B. Effect of vitamin D3 treatment on glucose metabolism and menstrual frequency in polycystic ovary syndrome women: a pilot study. J Endocrinol Investig. 2011;34:757-63.
31. Garg G, Kachhawa G, Ramot R, Khadgawat R, Tandon N, Sreenivas V, et al. Effect of vitamin D supplementation on insulin kinetics and cardiovascular risk factors in polycystic ovarian syndrome: a pilot study. Endocr Connect. 2015;4:108-16.
32. Kelly CJ, Speirs A, Gould GW, Petrie JR, Lyall H, Connell JM. Altered vascular function in young women with polycystic ovary syndrome. J Clin Endocrinol Metab. 2002;87:742-6.
33. Alvarez JA, Ashraf A. Role of vitamin d in insulin secretion and insulin sensitivity for glucose homeostasis. Int J Endocrinol. 2010;2010:351385.
34. Longenecker CT, Hileman CO, Carman TL, Ross AC, Seydafkan S, Brown TT, et al. Vitamin D supplementation and endothelial function in vitamin D deficient HIV-infected patients: a randomized placebo-controlled trial. Antivir Ther. 2012;17:613-21.
35. Akbari M, Mosazadeh M, Lankarani KB, Tabrizi R, Samimi M, Karamali M, et al. The effects of vitamin D supplementation on glucose metabolism and lipid profiles in patients with gestational diabetes: a systematic review and meta-analysis of randomized controlled trials. Horm Metab Res. 2017;49:647-53.
36. Kubiak JM, Thorsby PM, Kamycheva E, Jorde R. Vitamin D supplementation does not improve CVD risk factors in vitamin D insufficient subjects. Endocr Connect. 2018;7:840-9.
37. Li S, Chu Q, Ma J, Sun Y, Tao T, Huang R, et al. Discovery of novel lipid profiles in PCOS: do insulin and androgen oppositely regulate bioactive lipid production? J Clin Endocrinol Metab. 2017;102:810-21.
38. Wang H, Xia N, Yang Y, Peng DQ. Influence of vitamin D supplementation on plasma lipid profiles: a meta-analysis of randomized controlled trials. Lipids Health Dis. 2012;11:42. https://doi.org/10.1186/1476-511X-11-42.
39. Kaplan M, Kerry R, Aviram M, Hayek T. High glucose concentration increases macrophage cholesterol biosynthesis in diabetes through activation of the sterol regulatory element binding. Protein 1 (SREBP1): inhibitory effect of insulin. J Cardiovasc Pharmacol. 2008;52:324-32.