-
1
-
-
84919662775
-
Sodium glucose co-transporter-2 (SGLT2) inhibitors: a review of their basic and clinical pharmacology
-
COI: 1:CAS:528:DC%2BC2cXitVCgt7jI
-
Kalra S. Sodium glucose co-transporter-2 (SGLT2) inhibitors: a review of their basic and clinical pharmacology. Diabetes Ther. 2014;5(2):355–66
-
(2014)
Diabetes Ther.
, vol.5
, Issue.2
, pp. 355-366
-
-
Kalra, S.1
-
4
-
-
85051499059
-
-
Accessed April 2018
-
Boehringer Ingelheim Limited. Empagliflozin: summary of product characteristics. 2018. https://www.medicines.org.uk/emc/product/5441. Accessed April 2018
-
(2018)
Summary of Product Characteristics
-
-
-
5
-
-
85027543305
-
-
Accessed April 2018
-
National Institute for Health and Care Excellence. Type 2 diabetes in adults: management. 2017. https://www.nice.org.uk/guidance/ng28. Accessed April 2018
-
(2017)
Type 2 Diabetes in Adults: Management
-
-
-
6
-
-
85043232847
-
-
Edinburgh: SIGN '154' - as per SIGN permission guidelines, Accessed April 2018. Cited 15 Jun 2018
-
Scottish Intercollegiate Guideline Network (SIGN). Pharmacological management of glycaemic control in people with type 2 diabetes. Edinburgh: SIGN '154' - as per SIGN permission guidelines; 2017. http://www.sign.ac.uk/assets/sign154.pdf. Accessed April 2018. Cited 15 Jun 2018
-
(2017)
Pharmacological Management of Glycaemic Control in People with Type 2 Diabetes
-
-
-
7
-
-
85054158806
-
Canagliflozin, dapagliflozin and empagliflozin as monotherapies for treating type 2 diabetes
-
Accessed April 2018
-
National Institute for Health and Care Excellence. Canagliflozin, dapagliflozin and empagliflozin as monotherapies for treating type 2 diabetes. Technology appraisal guidance. 2016. https://www.nice.org.uk/guidance/ta390. Accessed April 2018
-
(2016)
Technology Appraisal Guidance
-
-
-
8
-
-
84958158486
-
Empagliflozin reduces body weight and indices of adipose distribution in patients with type 2 diabetes mellitus
-
COI: 1:CAS:528:DC%2BC2sXmtVKjs70%3D
-
Neeland IJ, McGuire DK, Chilton R, et al. Empagliflozin reduces body weight and indices of adipose distribution in patients with type 2 diabetes mellitus. Diab Vasc Dis Res. 2016;13(2):119–26
-
(2016)
Diab Vasc Dis Res.
, vol.13
, Issue.2
, pp. 119-126
-
-
Neeland, I.J.1
McGuire, D.K.2
Chilton, R.3
-
9
-
-
84858020943
-
Effects of dapagliflozin on body weight, total fat mass, and regional adipose tissue distribution in patients with type 2 diabetes mellitus with inadequate glycemic control on metformin
-
COI: 1:CAS:528:DC%2BC38Xkt1yms78%3D
-
Bolinder J, Ljunggren Ö, Kullberg J, et al. Effects of dapagliflozin on body weight, total fat mass, and regional adipose tissue distribution in patients with type 2 diabetes mellitus with inadequate glycemic control on metformin. J Clin Endocrinol Metab. 2012;97(3):1020–31
-
(2012)
J Clin Endocrinol Metab
, vol.97
, Issue.3
, pp. 1020-1031
-
-
Bolinder, J.1
Ljunggren, Ö.2
Kullberg, J.3
-
10
-
-
84978388879
-
Effects of canagliflozin on body weight and body composition in patients with type 2 diabetes over 104 weeks
-
Blonde L, Stenlöf K, Fung A, Xie J, Canovatchel W, Meininger G. Effects of canagliflozin on body weight and body composition in patients with type 2 diabetes over 104 weeks. Postgrad Med. 2016;128(4):371–80
-
(2016)
Postgrad Med
, vol.128
, Issue.4
, pp. 371-380
-
-
Blonde, L.1
Stenlöf, K.2
Fung, A.3
Xie, J.4
Canovatchel, W.5
Meininger, G.6
-
11
-
-
84960433486
-
SGLT-2 receptor inhibitors for treating patients with type 2 diabetes mellitus: a systematic review and network meta-analysis
-
Shyangdan DS, Uthman OA, Waugh N. SGLT-2 receptor inhibitors for treating patients with type 2 diabetes mellitus: a systematic review and network meta-analysis. BMJ Open. 2016;6(2):e009417
-
(2016)
BMJ Open
, vol.6
, Issue.2
-
-
Shyangdan, D.S.1
Uthman, O.A.2
Waugh, N.3
-
12
-
-
84944800184
-
Empagliflozin, cardiovascular outcomes, and mortality in type 2 diabetes
-
COI: 1:CAS:528:DC%2BC28XntVSkurs%3D
-
Zinman B, Wanner C, Lachin JM, et al. Empagliflozin, cardiovascular outcomes, and mortality in type 2 diabetes. N Engl J Med. 2015;373:2117–28
-
(2015)
N Engl J Med
, vol.373
, pp. 2117-2128
-
-
Zinman, B.1
Wanner, C.2
Lachin, J.M.3
-
14
-
-
85034212680
-
Cardiovascular outcomes and safety of empagliflozin in patients with type 2 diabetes mellitus and peripheral artery disease: a subanalysis of EMPA-REG OUTCOME
-
Verma S, Mazer CD, Al-Omran M, et al. Cardiovascular outcomes and safety of empagliflozin in patients with type 2 diabetes mellitus and peripheral artery disease: a subanalysis of EMPA-REG OUTCOME. Circ. 2018;137(4):405–7
-
(2018)
Circ.
, vol.137
, Issue.4
, pp. 405-407
-
-
Verma, S.1
Mazer, C.D.2
Al-Omran, M.3
-
15
-
-
84979895487
-
Empagliflozin and progression of kidney disease in type 2 diabetes
-
COI: 1:CAS:528:DC%2BC28XhvF2ksrfJ
-
Wanner C, Inzucchi SE, Lachin JM, et al. Empagliflozin and progression of kidney disease in type 2 diabetes. N Engl J Med. 2016;375(4):323–34
-
(2016)
N Engl J Med
, vol.375
, Issue.4
, pp. 323-334
-
-
Wanner, C.1
Inzucchi, S.E.2
Lachin, J.M.3
-
16
-
-
85023777061
-
Canagliflozin and cardiovascular and renal events in type 2 diabetes
-
COI: 1:CAS:528:DC%2BC2sXhsVKktrbE
-
Neal B, Perkovic V, Mahaffey KW, et al. Canagliflozin and cardiovascular and renal events in type 2 diabetes. N Engl J Med. 2017;377(7):644–57
-
(2017)
N Engl J Med
, vol.377
, Issue.7
, pp. 644-657
-
-
Neal, B.1
Perkovic, V.2
Mahaffey, K.W.3
-
17
-
-
85048347907
-
Cardiovascular outcomes and risks after initiation of a sodium glucose co-transporter 2 inhibitor: results from the EASEL population-based cohort study
-
COI: 1:CAS:528:DC%2BC1cXmslGqu7g%3D
-
Udell JA, Yuan Z, Rush T, Sicignano NM, Galitz M, Rosenthal N. Cardiovascular outcomes and risks after initiation of a sodium glucose co-transporter 2 inhibitor: results from the EASEL population-based cohort study. Circulation. 2018;137(14):1450–9
-
(2018)
Circulation
, vol.137
, Issue.14
, pp. 1450-1459
-
-
Udell, J.A.1
Yuan, Z.2
Rush, T.3
Sicignano, N.M.4
Galitz, M.5
Rosenthal, N.6
-
18
-
-
85019731757
-
Lower risk of heart failure and death in patients initiated on SGLT-2 inhibitors versus other glucose-lowering drugs: the CVD-REAL study
-
COI: 1:CAS:528:DC%2BC2sXhtFOktL3K
-
Kosiborod M, Cavender MA, Fu AZ, et al. Lower risk of heart failure and death in patients initiated on SGLT-2 inhibitors versus other glucose-lowering drugs: the CVD-REAL study. Circulation. 2017;136:249–59
-
(2017)
Circulation
, vol.136
, pp. 249-259
-
-
Kosiborod, M.1
Cavender, M.A.2
Fu, A.Z.3
-
19
-
-
84901196813
-
The importance of weight management in type 2 diabetes mellitus
-
COI: 1:STN:280:DC%2BC2cvmtVCiuw%3D%3D
-
Wilding JP. The importance of weight management in type 2 diabetes mellitus. Int J Clin Pract. 2014;68(6):682–91
-
(2014)
Int J Clin Pract
, vol.68
, Issue.6
, pp. 682-691
-
-
Wilding, J.P.1
-
20
-
-
0033533596
-
Diabetes and Cardiovascular Disease
-
COI: 1:STN:280:DyaK1Mvgs1KjsA%3D%3D
-
Grundy SM, Benjamin IJ, Burke GL, et al. Diabetes and cardiovascular disease: a statement for healthcare professionals from the American Heart Association. Circulation. 1999;100:1134–46
-
(1999)
Circulation
, vol.100
, Issue.10
, pp. 1134-1146
-
-
Grundy, S.M.1
Benjamin, I.J.2
Burke, G.L.3
Chait, A.4
Eckel, R.H.5
Howard, B.V.6
Mitch, W.7
Smith, S.C.8
Sowers, J.R.9
-
21
-
-
85046093511
-
Association between use of sodium-glucose cotransporter 2 inhibitors, glucagon-like peptide 1 agonists, and dipeptidyl peptidase 4 inhibitors with all-cause mortality in patients with type 2 diabetes
-
COI: 1:CAS:528:DC%2BC1cXotVCmsLY%3D
-
Zheng SL, Roddick AJ, Aghar-Jaffar R, et al. Association between use of sodium-glucose cotransporter 2 inhibitors, glucagon-like peptide 1 agonists, and dipeptidyl peptidase 4 inhibitors with all-cause mortality in patients with type 2 diabetes. JAMA. 2018;319(15):1580–91
-
(2018)
JAMA
, vol.319
, Issue.15
, pp. 1580-1591
-
-
Zheng, S.L.1
Roddick, A.J.2
Aghar-Jaffar, R.3
-
22
-
-
33750469241
-
Standards of medical care in diabetes
-
American Diabetes Association. Standards of medical care in diabetes. Diabetes Care. 2017;40(1):S1–2
-
(2017)
Diabetes Care
, vol.40
, Issue.1
, pp. S1-S2
-
-
-
23
-
-
85020470639
-
Optimizing the analysis strategy for the CANVAS Program: a prespecified plan for the integrated analyses of the CANVAS and CANVAS- R trials
-
Neal B, Perkovic V, Mahaffey KW, et al. Optimizing the analysis strategy for the CANVAS Program: a prespecified plan for the integrated analyses of the CANVAS and CANVAS- R trials. Diabetes Obes Metab. 2017;19(7):926–35
-
(2017)
Diabetes Obes Metab
, vol.19
, Issue.7
, pp. 926-935
-
-
Neal, B.1
Perkovic, V.2
Mahaffey, K.W.3
-
24
-
-
85047995723
-
Rates of myocardial infarction and stroke in patients initiating treatment with SGLT2-inhibitors versus other glucose-lowering agents in real-world clinical practice: Results from the CVD-REAL study
-
Kosiborod M, Birkeland KI, Cavender MA et al. Rates of myocardial infarction and stroke in patients initiating treatment with SGLT2-inhibitors versus other glucose-lowering agents in real-world clinical practice: Results from the CVD-REAL study. Diabetes Obes Metab. 2018. 20(8):1983–7. 10.1111/dom.13299
-
(2018)
Diabetes Obes Metab.
, vol.20
, Issue.8
, pp. 1983-1987
-
-
Kosiborod, M.1
Birkeland, K.I.2
Cavender, M.A.3
-
25
-
-
85042008156
-
DECLARE-TIMI 58: Participants’ baseline characteristics
-
COI: 1:CAS:528:DC%2BC1cXotFSlt70%3D
-
Raz I, Mosenzon O, Bonaca MP, et al. DECLARE-TIMI 58: participants’ baseline characteristics. Diabetes Obes Metab. 2018;20(5):1102–10 (Epub ahead of print)
-
(2018)
Diabetes, Obesity and Metabolism
, vol.20
, Issue.5
, pp. 1102-1110
-
-
Raz, I.1
Mosenzon, O.2
Bonaca, M.P.3
Cahn, A.4
Kato, E.T.5
Silverman, M.G.6
Bhatt, D.L.7
Leiter, L.A.8
McGuire, D.K.9
Wilding, J.P.H.10
Gause-Nilsson, I.A.M.11
Langkilde, A.M.12
Johansson, P.A.13
Sabatine, M.S.14
Wiviott, S.D.15
-
26
-
-
85045458725
-
The design and rationale for the Dapagliflozin Effect on Cardiovascular Events (DECLARE)–TIMI 58 Trial
-
COI: 1:CAS:528:DC%2BC1cXot1Cns70%3D
-
Wiviott SD, Raz I, Bonaca MP, et al. The design and rationale for the dapagliflozin effect on cardiovascular events (DECLARE)–TIMI 58 Trial. Am Heart J. 2018;200:83–9
-
(2018)
American Heart Journal
, vol.200
, pp. 83-89
-
-
Wiviott, S.D.1
Raz, I.2
Bonaca, M.P.3
Mosenzon, O.4
Kato, E.T.5
Cahn, A.6
Silverman, M.G.7
Bansilal, S.8
Bhatt, D.L.9
Leiter, L.A.10
McGuire, D.K.11
Wilding, J.P.H.12
Gause-Nilsson, I.A.M.13
Langkilde, A.M.14
Johansson, P.A.15
Sabatine, M.S.16
-
27
-
-
85038113623
-
The Canagliflozin and Renal Endpoints in Diabetes with Established Nephropathy Clinical Evaluation (CREDENCE) Study Rationale, Design, and Baseline Characteristics
-
COI: 1:CAS:528:DC%2BC1cXhtVKnt7k%3D
-
Jardine MJ, Mahaffey KW, Neal B, et al. The Canagliflozin and Renal Endpoints in Diabetes with Established Nephropathy Clinical Evaluation (CREDENCE) study rationale, design, and baseline characteristics. Am J Nephrol. 2017;46(6):462–72
-
(2017)
American Journal of Nephrology
, vol.46
, Issue.6
, pp. 462-472
-
-
Jardine, M.J.1
Mahaffey, K.W.2
Neal, B.3
Agarwal, R.4
Bakris, G.L.5
Brenner, B.M.6
Bull, S.7
Cannon, C.P.8
Charytan, D.M.9
de Zeeuw, D.10
Edwards, R.11
Greene, T.12
Heerspink, H.J.L.13
Levin, A.14
Pollock, C.15
Wheeler, D.C.16
Xie, J.17
Zhang, H.18
Zinman, B.19
Desai, M.20
Perkovic, V.21
more..
-
29
-
-
79957827666
-
Lower estimated glomerular filtration rate and higher albuminuria are associated with mortality and end-stage renal disease. A collaborative meta-analysis of kidney disease population cohorts
-
COI: 1:CAS:528:DC%2BC3MXmvFyjsbs%3D
-
Astor BC, Matsushita K, Gansevoort RT, et al. Lower estimated glomerular filtration rate and higher albuminuria are associated with mortality and end-stage renal disease. A collaborative meta-analysis of kidney disease population cohorts. Kidney Int. 2011;79(12):1331–40
-
(2011)
Kidney Int
, vol.79
, Issue.12
, pp. 1331-1340
-
-
Astor, B.C.1
Matsushita, K.2
Gansevoort, R.T.3
-
30
-
-
85021102407
-
Use of SGLT2 inhibitors for diabetes and risk of infection: analysis using general practice records from the NPS MedicineWise MedicineInsight program
-
COI: 1:CAS:528:DC%2BC2sXhtVWqs7fF
-
Gadzhanova S, Pratt N, Roughead E. Use of SGLT2 inhibitors for diabetes and risk of infection: analysis using general practice records from the NPS MedicineWise MedicineInsight program. Diabetes Res Clin Pract. 2017;130:180–5
-
(2017)
Diabetes Res Clin Pract
, vol.130
, pp. 180-185
-
-
Gadzhanova, S.1
Pratt, N.2
Roughead, E.3
-
31
-
-
84898917720
-
Genital and urinary tract infections in diabetes: impact of pharmacologically-induced glucosuria
-
COI: 1:CAS:528:DC%2BC2cXisFCht7Y%3D
-
Geerlings S, Fonseca V, Castro-Diaz D, List J, Parikh S. Genital and urinary tract infections in diabetes: impact of pharmacologically-induced glucosuria. Diabetes Res Clin Pract. 2014;103(3):373–81
-
(2014)
Diabetes Res Clin Pract
, vol.103
, Issue.3
, pp. 373-381
-
-
Geerlings, S.1
Fonseca, V.2
Castro-Diaz, D.3
List, J.4
Parikh, S.5
-
32
-
-
85007022677
-
Urinary tract and genital infections in patients with type 2 diabetes treated with sodium-glucose co-transporter 2 inhibitors: a meta-analysis of randomized controlled trials
-
COI: 1:CAS:528:DC%2BC2sXjtlCnsLc%3D
-
Li D, Wang T, Shen S, Fang Z, Dong Y, Tang H. Urinary tract and genital infections in patients with type 2 diabetes treated with sodium-glucose co-transporter 2 inhibitors: a meta-analysis of randomized controlled trials. Diabetes Obes Metab. 2017;19(3):348–55
-
(2017)
Diabetes Obes Metab
, vol.19
, Issue.3
, pp. 348-355
-
-
Li, D.1
Wang, T.2
Shen, S.3
Fang, Z.4
Dong, Y.5
Tang, H.6
-
33
-
-
85054186373
-
-
Accessed April 2018
-
European Medicines Agency. Pharmacovigilance Risk Assessment Committee (PRAC) assessment report. 2016. http://www.ema.europa.eu/docs/en_GB/document_library/EPAR_-Assessment_Report_-_Variation/human/002656/WC500230546.pdf. Accessed April 2018
-
(2016)
Pharmacovigilance Risk Assessment Committee (PRAC) assessment report
-
-
-
34
-
-
85038950538
-
Empagliflozin and assessment of lower-limb amputations in the EMPA-REG OUTCOME trial
-
Inzucchi SE, Iliev H, Pfarr E, Zinman B. Empagliflozin and assessment of lower-limb amputations in the EMPA-REG OUTCOME trial. Diabetes Care. 2018;41(1):e4–5
-
(2018)
Diabetes Care
, vol.41
, Issue.1
, pp. e4-e5
-
-
Inzucchi, S.E.1
Iliev, H.2
Pfarr, E.3
Zinman, B.4
-
35
-
-
85024835007
-
SGLT2 inhibitors and amputations in the US FDA adverse event reporting system
-
Fadini GP, Avogaro A. SGLT2 inhibitors and amputations in the US FDA adverse event reporting system. Lancet Diabetes Endocrinol. 2017;5(9):680–1
-
(2017)
Lancet Diabetes Endocrinol.
, vol.5
, Issue.9
, pp. 680-681
-
-
Fadini, G.P.1
Avogaro, A.2
-
36
-
-
85043604063
-
SGLT-2 inhibitors and the risk of lower-limb amputation: Is this a class effect?
-
COI: 1:CAS:528:DC%2BC1cXpsFOiu7c%3D
-
Khouri C, Cracowski JL, Roustit M. SGLT-2 inhibitors and the risk of lower-limb amputation: is this a class effect? Diabetes Obes Metab. 2018;20(6):1531–4
-
(2018)
Diabetes, Obesity and Metabolism
, vol.20
, Issue.6
, pp. 1531-1534
-
-
Khouri, C.1
Cracowski, J.-L.2
Roustit, M.3
-
38
-
-
84954514891
-
Effects of canagliflozin on fracture risk in patients with type 2 diabetes mellitus
-
COI: 1:CAS:528:DC%2BC28XotlWqu7c%3D
-
Watts NB, Bilezikian JP, Usiskin K, Edwards R, Desai M, Law G, Meininger G. Effects of canagliflozin on fracture risk in patients with type 2 diabetes mellitus. J Clin Endocrinol Metab. 2016;101(1):157–66
-
(2016)
J Clin Endocrinol Metab
, vol.101
, Issue.1
, pp. 157-166
-
-
Watts, N.B.1
Bilezikian, J.P.2
Usiskin, K.3
Edwards, R.4
Desai, M.5
Law, G.6
Meininger, G.7
-
39
-
-
84954564720
-
Evaluation of bone mineral density and bone biomarkers in patients with type 2 diabetes treated with canagliflozin
-
COI: 1:CAS:528:DC%2BC28XotlWqtb4%3D
-
Bilezikian JP, Watts NB, Usiskin K, et al. Evaluation of bone mineral density and bone biomarkers in patients with type 2 diabetes treated with canagliflozin. J Clin Endocrinol Metab. 2016;101(1):44–51
-
(2016)
J Clin Endocrinol Metab
, vol.101
, Issue.1
, pp. 44-51
-
-
Bilezikian, J.P.1
Watts, N.B.2
Usiskin, K.3
-
41
-
-
85011900861
-
-
Accessed April 2018
-
UK Medicines and Healthcare Products Regulatory Agency. 2016. SGLT2 inhibitors: updated advice on the risk of diabetic ketoacidosis. https://www.gov.uk/drug-safety-update/sglt2-inhibitors-updated-advice-on-the-risk-of-diabetic-ketoacidosis. Accessed April 2018
-
(2016)
SGLT2 Inhibitors: Updated Advice on the Risk of Diabetic Ketoacidosis
-
-
-
43
-
-
85054172020
-
-
Accessed April 2018
-
Diabetes UK. Dealing with illness. https://www.diabetes.org.uk/guide-to-diabetes/life-with-diabetes/illness. Accessed April 2018
-
Dealing with Illness
-
-
-
44
-
-
85054190092
-
Clinical knowledge summary
-
August, Accessed April 2018
-
National Institute for Health and Care Excellence. Clinical knowledge summary. Diabetes—type 2. August 2017. https://cks.nice.org.uk/diabetes-type-2#!scenarioclarification:7. Accessed April 2018
-
(2017)
Diabetes—type 2
-
-
-
46
-
-
84942312400
-
Assessing bladder cancer risk in type 2 diabetes clinical trials: the dapagliflozin drug development program as a ‘case study’
-
COI: 1:CAS:528:DC%2BC2MXhsVOqtLbJ
-
Ptaszynska A, Cohen SM, Messing EM, Reilly TP, Johnsson E, Johnsson K. Assessing bladder cancer risk in type 2 diabetes clinical trials: the dapagliflozin drug development program as a ‘case study’. Diabetes Ther. 2015;6(3):357–75
-
(2015)
Diabetes Ther.
, vol.6
, Issue.3
, pp. 357-375
-
-
Ptaszynska, A.1
Cohen, S.M.2
Messing, E.M.3
Reilly, T.P.4
Johnsson, E.5
Johnsson, K.6
-
47
-
-
85025110453
-
SGLT2 inhibitors and risk of cancer in type 2 diabetes: a systematic review and meta-analysis of randomised controlled trials
-
COI: 1:CAS:528:DC%2BC2sXhtF2qtL3P
-
Tang H, Dai Q, Shi W, Zhai S, Song Y, Han J. SGLT2 inhibitors and risk of cancer in type 2 diabetes: a systematic review and meta-analysis of randomised controlled trials. Diabetologia. 2017;60(10):1862–72
-
(2017)
Diabetologia
, vol.60
, Issue.10
, pp. 1862-1872
-
-
Tang, H.1
Dai, Q.2
Shi, W.3
Zhai, S.4
Song, Y.5
Han, J.6
-
48
-
-
85054087990
-
-
Accessed June 2018
-
NHS Scotland. Polypharmacy guidance—realistic prescribing. 2018. http://www.therapeutics.scot.nhs.uk/wp-content/uploads/2018/04/Polypharmacy-Guidance-2018.pdf. Accessed June 2018
-
(2018)
Polypharmacy guidance—realistic Prescribing
-
-
|