Gene editing restores dystrophin expression in a canine model of Duchenne muscular dystrophy

Science

Volumn 362, Issue 6410, 2018, Pages 86-91

  Amoasii, Leonela ^a,b   Hildyard, John C W ^c   Li, Hui ^a   Sanchez Ortiz, Efrain ^a   Mireault, Alex ^a   Caballero, Daniel ^a   Harron, Rachel ^c   Stathopoulou, Thaleia Rengina ^c   Massey, Claire ^c   Shelton, John M ^d   Bassel Duby, Rhonda ^a   Piercy, Richard J ^c   Olson, Eric N ^a  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^b Exonics Therapeutics   (United States)

^c ROYAL VETERINARY COLLEGE   (United Kingdom)

^d UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENO-ASSOCIATED VIRUS; ANIMALIA; CANIS FAMILIARIS;

DYSTROPHIN;

ADENOVIRIDAE; ANIMAL; CRISPR CAS SYSTEM; DISEASE MODEL; DOG; DUCHENNE MUSCULAR DYSTROPHY; FEMALE; GENE EDITING; GENE TRANSFER; GENETICS; MALE; METABOLISM; PROCEDURES;

ADENOVIRIDAE; ANIMALS; CRISPR-CAS SYSTEMS; DISEASE MODELS, ANIMAL; DOGS; DYSTROPHIN; FEMALE; GENE EDITING; GENE TRANSFER TECHNIQUES; MALE; MUSCULAR DYSTROPHY, DUCHENNE;

EID: 85053601183     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.aau1549     Document Type: Article

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