BECN1 is a new driver of ferroptosis

Autophagy

Volumn 14, Issue 12, 2018, Pages 2173-2175

  Kang, Rui ^a,b,c   Zhu, Shan ^a   Zeh, Herbert J ^b,c   Klionsky, Daniel J ^d   Tang, Daolin ^a,b,c  

^a GUANGZHOU MEDICAL UNIVERSITY   (China)

^b UNIVERSITY OF PITTSBURGH MEDICAL CENTER   (United States)

^c UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^d UNIVERSITY OF MICHIGAN   (United States)

Author keywords

AMPK; autophagy; BECN1; cancer; chemotherapy; ferroptosis; phosphorylation; redox; SLC7A11

Indexed keywords

ANTIPORTER; BECLIN 1; CYSTEINE; GLUTAMIC ACID; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; MICROTUBULE ASSOCIATED PROTEIN 1; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN; PROTEIN SLC7A11; SALAZOSULFAPYRIDINE; UNCLASSIFIED DRUG;

AUTOPHAGY; CANCER CELL; CELL DEATH; COMPLEX FORMATION; ENERGY METABOLISM; FERROPTOSIS; HUMAN; LIPID PEROXIDATION; MACROAUTOPHAGY; NOTE; PROTEIN DEGRADATION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; APOPTOSIS; PHOSPHORYLATION;

AMP-ACTIVATED PROTEIN KINASES; APOPTOSIS; AUTOPHAGY; LIPID PEROXIDATION; PHOSPHORYLATION;

EID: 85053322934     PISSN: 15548627     EISSN: 15548635     Source Type: Journal    
DOI: 10.1080/15548627.2018.1513758     Document Type: Note

References (1)

1. Song X, Zhu S, Chen P, et al. AMPK-Mediated BECN1 phosphorylation promotes ferroptosis by directly blocking system X(c)(-) activity. Curr Biol. 2018 Aug 6;28(15):2388–2399.e5. Epub 2018 Jul 26. PubMed PMID: 30057310.