-
3
-
-
85015775820
-
Emerging novel therapeutic agents in the treatment of patients with gastroesophageal and gastric adenocarcinoma
-
Anandappa G, Chau I: Emerging novel therapeutic agents in the treatment of patients with gastroesophageal and gastric adenocarcinoma. Hematol Oncol Clin North Am 31:529-544, 2017
-
(2017)
Hematol Oncol Clin North Am
, vol.31
, pp. 529-544
-
-
Anandappa, G.1
Chau, I.2
-
5
-
-
85042561938
-
Genetic predictors of response to systemic therapy in esophagogastric cancer
-
Janjigian YY, Sanchez-Vega F, Jonsson P, et al: Genetic predictors of response to systemic therapy in esophagogastric cancer. Cancer Discov 8:49-58, 2018
-
(2018)
Cancer Discov
, vol.8
, pp. 49-58
-
-
Janjigian, Y.Y.1
Sanchez-Vega, F.2
Jonsson, P.3
-
6
-
-
84907270779
-
Cancer genome atlas research network: Comprehensive molecular characterization of gastric adenocarcinoma
-
Cancer Genome Atlas Research Network: Comprehensive molecular characterization of gastric adenocarcinoma. Nature 513:202-209, 2014
-
(2014)
Nature
, vol.513
, pp. 202-209
-
-
-
7
-
-
85016278868
-
Cancer genome atlas research network: Integrated genomic characterization of oesophageal carcinoma
-
Cancer Genome Atlas Research Network: Integrated genomic characterization of oesophageal carcinoma. Nature 541:169-175, 2017
-
(2017)
Nature
, vol.541
, pp. 169-175
-
-
-
8
-
-
85000836785
-
The clinicopathological and prognostic significance of pd-l1 expression in gastric cancer: A meta-analysis of 10 studies with 1,901 patients
-
Zhang M, Dong Y, Liu H, et al: The clinicopathological and prognostic significance of PD-L1 expression in gastric cancer: A meta-analysis of 10 studies with 1,901 patients. Sci Rep 6:37933, 2016
-
(2016)
Sci Rep
, vol.6
, pp. 37933
-
-
Zhang, M.1
Dong, Y.2
Liu, H.3
-
9
-
-
84964779633
-
Pembrolizumab for patients with pd-l1-positive advanced gastric cancer (keynote-012): A multicentre, openlabel, phase 1b trial
-
Muro K, Chung HC, Shankaran V, et al: Pembrolizumab for patients with PD-L1-positive advanced gastric cancer (KEYNOTE-012): A multicentre, openlabel, phase 1b trial. Lancet Oncol 17:717-726, 2016
-
(2016)
Lancet Oncol
, vol.17
, pp. 717-726
-
-
Muro, K.1
Chung, H.C.2
Shankaran, V.3
-
10
-
-
85047499076
-
Safety and efficacy of pembrolizumab monotherapy in patients with previously treated advanced gastric and gastroesophageal junction cancer: Phase 2 clinical keynote-059 trial
-
Fuchs CS, Doi T, Jang RW, et al: Safety and efficacy of pembrolizumab monotherapy in patients with previously treated advanced gastric and gastroesophageal junction cancer: Phase 2 clinical KEYNOTE-059 trial. JAMA Oncol 4:e180013; 2018
-
(2018)
JAMA Oncol
, vol.4
, pp. e180013
-
-
Fuchs, C.S.1
Doi, T.2
Jang, R.W.3
-
11
-
-
85006292884
-
Checkmate-032: Phase i/II, open-label study of safety and activity of nivolumab (nivo) alone or with ipilimumab (ipi) in advanced and metastatic (a/m) gastric cancer (gc
-
abstr 4010
-
Janjigian Y, Bendell JC, Calvo E, et al: CheckMate-032: Phase I/II, open-label study of safety and activity of nivolumab (NIVO) alone or with ipilimumab (IPI) in advanced and metastatic (A/M) gastric cancer (GC). J Clin Oncol 34, 2016 (suppl; abstr 4010)
-
(2016)
J Clin Oncol
, vol.34
-
-
Janjigian, Y.1
Bendell, J.C.2
Calvo, E.3
-
12
-
-
85030626436
-
Nivolumab in patients with advanced gastric or gastro-oesophageal junction cancer refractory to, or intolerant of, at least two previous chemotherapy regimens (ono-4538-12, ATTRACTION-2): A randomised, double-blind, placebo-controlled, phase 3 trial
-
Kang YK, Boku N, Satoh T, et al: Nivolumab in patients with advanced gastric or gastro-oesophageal junction cancer refractory to, or intolerant of, at least two previous chemotherapy regimens (ONO-4538-12, ATTRACTION-2): A randomised, double-blind, placebo-controlled, phase 3 trial. Lancet 390: 2461-2471, 2017
-
(2017)
Lancet
, vol.390
, pp. 2461-2471
-
-
Kang, Y.K.1
Boku, N.2
Satoh, T.3
-
13
-
-
77749279776
-
Pd-1 and ctla-4 combination blockade expands infiltrating t cells and reduces regulatory t and myeloid cells within b16 melanoma tumors
-
Curran MA, Montalvo W, Yagita H, et al: PD-1 and CTLA-4 combination blockade expands infiltrating T cells and reduces regulatory T and myeloid cells within B16 melanoma tumors. Proc Natl Acad Sci USA 107:4275-4280, 2010
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 4275-4280
-
-
Curran, M.A.1
Montalvo, W.2
Yagita, H.3
-
14
-
-
84880322360
-
Antitumor activity of concurrent blockade of immune checkpoint molecules ctla-4 and pd-1 in preclinical models
-
abstr 3061
-
Selby M, Englehardt J, Lu L-S, et al: Antitumor activity of concurrent blockade of immune checkpoint molecules CTLA-4 and PD-1 in preclinical models. J Clin Oncol 31, 2013 (suppl; abstr 3061)
-
(2013)
J Clin Oncol
, vol.31
-
-
Selby, M.1
Englehardt, J.2
Lu, L.-S.3
-
15
-
-
84936147067
-
Combined nivolumab and ipilimumab or monotherapy in untreated melanoma
-
Larkin J, Chiarion-Sileni V, Gonzalez R, et al: Combined nivolumab and ipilimumab or monotherapy in untreated melanoma. N Engl J Med 373: 23-34, 2015
-
(2015)
N Engl J Med
, vol.373
, pp. 23-34
-
-
Larkin, J.1
Chiarion-Sileni, V.2
Gonzalez, R.3
-
16
-
-
84971620553
-
Nivolumab alone and nivolumab plus ipilimumab in recurrent small-cell lung cancer (checkmate 032): A multicentre open-label phase 1/2 trial
-
Antonia SJ, Lopez-Martin JA, Bendell J, et al: Nivolumab alone and nivolumab plus ipilimumab in recurrent small-cell lung cancer (CheckMate 032): A multicentre, open-label, phase 1/2 trial. Lancet Oncol 17:883-895, 2016
-
(2016)
Lancet Oncol
, vol.17
, pp. 883-895
-
-
Antonia, S.J.1
Lopez-Martin, J.A.2
Bendell, J.3
-
17
-
-
85043396361
-
Durable clinical benefit with nivolumab plus ipilimumab in DNA mismatch repair-deficient/microsatellite instability-high metastatic colorectal cancer
-
Overman MJ, Lonardi S, Wong KYM, et al: Durable clinical benefit with nivolumab plus ipilimumab in DNA mismatch repair-deficient/microsatellite instability-high metastatic colorectal cancer. J Clin Oncol 36:773-779, 2018
-
(2018)
J Clin Oncol
, vol.36
, pp. 773-779
-
-
Overman, M.J.1
Lonardi, S.2
Kym, W.3
-
18
-
-
57849117384
-
New response evaluation criteria in solid tumours: Revised recist guideline (version 1.1
-
Eisenhauer EA, Therasse P, Bogaerts J, et al: New response evaluation criteria in solid tumours: Revised RECIST guideline (version 1.1). Eur J Cancer 45:228-247, 2009
-
(2009)
Eur J Cancer
, vol.45
, pp. 228-247
-
-
Eisenhauer, E.A.1
Therasse, P.2
Bogaerts, J.3
-
20
-
-
10744233937
-
Revised bethesda guidelines for hereditary nonpolyposis colorectal cancer (lynch syndrome) and microsatellite instability
-
Umar A, Boland CR, Terdiman JP, et al: Revised Bethesda guidelines for hereditary nonpolyposis colorectal cancer (Lynch syndrome) and microsatellite instability. J Natl Cancer Inst 96: 261-268, 2004
-
(2004)
J Natl Cancer Inst
, vol.96
, pp. 261-268
-
-
Umar, A.1
Boland, C.R.2
Terdiman, J.P.3
-
21
-
-
0024536437
-
Optimal two-stage designs for phase II clinical trials
-
Simon R: Optimal two-stage designs for phase II clinical trials. Control Clin Trials 10:1-10, 1989
-
(1989)
Control Clin Trials
, vol.10
, pp. 1-10
-
-
Simon, R.1
-
22
-
-
84879777241
-
Nivolumab plus ipilimumab in advanced melanoma
-
Wolchok JD, Kluger H, Callahan MK, et al: Nivolumab plus ipilimumab in advanced melanoma. N Engl J Med 369:122-133, 2013
-
(2013)
N Engl J Med
, vol.369
, pp. 122-133
-
-
Wolchok, J.D.1
Kluger, H.2
Callahan, M.K.3
-
23
-
-
85032035687
-
Safety and efficacy of nivolumab in combination with ipilimumab in metastatic renal cell carcinoma: The checkmate 016 study
-
Hammers HJ, Plimack ER, Infante JR, et al: Safety and efficacy of nivolumab in combination with ipilimumab in metastatic renal cell carcinoma: The CheckMate 016 Study. J Clin Oncol 35:3851-3858, 2017
-
(2017)
J Clin Oncol
, vol.35
, pp. 3851-3858
-
-
Hammers, H.J.1
Plimack, E.R.2
Infante, J.R.3
-
24
-
-
85007425840
-
Nivolumab plus ipilimumab as first-line treatment for advanced non-small-cell lung cancer (checkmate 012): Results of an openlabel, phase 1, multicohort study
-
Hellmann MD, Rizvi NA, Goldman JW, et al: Nivolumab plus ipilimumab as first-line treatment for advanced non-small-cell lung cancer (CheckMate 012): Results of an openlabel, phase 1, multicohort study. Lancet Oncol 18:31-41, 2017
-
(2017)
Lancet Oncol
, vol.18
, pp. 31-41
-
-
Hellmann, M.D.1
Rizvi, N.A.2
Goldman, J.W.3
-
25
-
-
85054132486
-
Keynote-059 cohort 1: Pembrolizumab (pembro) monotherapy in previously treated advanced gastric or gastroesophageal junction (g/gej) cancer in patients (pts) with pd-l1+ tumors: Asian subgroup analysis
-
abstr 723
-
Muro K, Fuchs CS, Jang RW, et al: KEYNOTE-059 cohort 1: Pembrolizumab (Pembro) monotherapy in previously treated advanced gastric or gastroesophageal junction (G/GEJ) cancer in patients (Pts) with PD-L1+ tumors: Asian subgroup analysis. J Clin Oncol 36, 2018 (suppl, abstr 723)
-
(2018)
J Clin Oncol
, vol.36
-
-
Muro, K.1
Fuchs, C.S.2
Jang, R.W.3
-
27
-
-
85026265866
-
Mismatch repair deficiency predicts response of solid tumors to pd-1 blockade
-
Le DT, Durham JN, Smith KN, et al: Mismatch repair deficiency predicts response of solid tumors to PD-1 blockade. Science 357:409-413, 2017
-
(2017)
Science
, vol.357
, pp. 409-413
-
-
Le, D.T.1
Durham, J.N.2
Smith, K.N.3
-
28
-
-
84932628341
-
Pd-1 blockade in tumors with mismatch-repair deficiency
-
Le DT, Uram JN,Wang H, et al: PD-1 blockade in tumors with mismatch-repair deficiency. N Engl J Med 372:2509-2520, 2015
-
(2015)
N Engl J Med
, vol.372
, pp. 2509-2520
-
-
Le, D.T.1
Uram, J.N.2
Wang, H.3
|