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Volumn 3, Issue 10, 2018, Pages 1011-1019

Enrollment of Older Patients, Women, and Racial and Ethnic Minorities in Contemporary Heart Failure Clinical Trials: A Systematic Review

Author keywords

[No Author keywords available]

Indexed keywords

AGE; AGED; CLINICAL TRIAL (TOPIC); EPIDEMIOLOGY; ETHNIC GROUP; FEMALE; HEART EJECTION FRACTION; HEART FAILURE; HEART FAILURE WITH REDUCED EJECTION FRACTION; HOSPITALIZATION; HUMAN; PRIORITY JOURNAL; RESEARCH SUBJECT; REVIEW; SYSTEMATIC REVIEW; TREND STUDY; COMPARATIVE STUDY; ETHICS; ETHNOLOGY; HEART STROKE VOLUME; MIDDLE AGED; PATIENT SELECTION;

EID: 85052944853     PISSN: 23806583     EISSN: 23806591     Source Type: Journal    
DOI: 10.1001/jamacardio.2018.2559     Document Type: Review
Times cited : (163)

References (29)
  • 1
    • 26444562493 scopus 로고    scopus 로고
    • Heart failure in African Americans
    • 16226931
    • Yancy CW. Heart failure in African Americans. Am J Cardiol. 2005; 96 (7B): 3i-12i. 16226931
    • (2005) Am J Cardiol , vol.96 , Issue.7 B , pp. 3i-12i
    • Yancy, C.W.1
  • 3
    • 85041467290 scopus 로고    scopus 로고
    • Racial differences in plasma levels of N-terminal pro-B-type natriuretic peptide and outcomes: The Reasons for Geographic and Racial Differences in Stroke (REGARDS) Study
    • 29167879
    • Bajaj NS, Gutiérrez OM, Arora G, Racial differences in plasma levels of N-terminal pro-B-type natriuretic peptide and outcomes: the Reasons for Geographic and Racial Differences in Stroke (REGARDS) Study. JAMA Cardiol. 2018; 3 (1): 11-17. 29167879
    • (2018) JAMA Cardiol , vol.3 , Issue.1 , pp. 11-17
    • Bajaj, N.S.1    Gutiérrez, O.M.2    Arora, G.3
  • 4
    • 84926150050 scopus 로고    scopus 로고
    • G-protein beta-3 subunit genotype predicts enhanced benefit of fixed-dose isosorbide dinitrate and hydralazine: Results of A-HeFT
    • 25306451
    • McNamara DM, Taylor AL, Tam SW, G-protein beta-3 subunit genotype predicts enhanced benefit of fixed-dose isosorbide dinitrate and hydralazine: results of A-HeFT. JACC Heart Fail. 2014; 2 (6): 551-557. 25306451
    • (2014) JACC Heart Fail , vol.2 , Issue.6 , pp. 551-557
    • McNamara, D.M.1    Taylor, A.L.2    Tam, S.W.3
  • 5
    • 85052190500 scopus 로고    scopus 로고
    • Transforming drug development in heart failure: Navigating the regulatory crossroads
    • 27707750
    • Vaduganathan M, Butler J, Gheorghiade M. Transforming drug development in heart failure: navigating the regulatory crossroads. Circ Heart Fail. 2016; 9 (10): 9. 27707750
    • (2016) Circ Heart Fail , vol.9 , Issue.10 , pp. 9
    • Vaduganathan, M.1    Butler, J.2    Gheorghiade, M.3
  • 7
    • 84873884896 scopus 로고    scopus 로고
    • Impact of ancestry and common genetic variants on QT interval in African Americans
    • 23166209
    • Smith JG, Avery CL, Evans DS,; CARe and COGENT consortia. Impact of ancestry and common genetic variants on QT interval in African Americans. Circ Cardiovasc Genet. 2012; 5 (6): 647-655. 23166209
    • (2012) Circ Cardiovasc Genet , vol.5 , Issue.6 , pp. 647-655
    • Smith, J.G.1    Avery, C.L.2    Evans, D.S.3
  • 8
    • 0037067884 scopus 로고    scopus 로고
    • Representation of the elderly, women, and minorities in heart failure clinical trials
    • 12153370
    • Heiat A, Gross CP, Krumholz HM. Representation of the elderly, women, and minorities in heart failure clinical trials. Arch Intern Med. 2002; 162 (15): 1682-1688. 12153370
    • (2002) Arch Intern Med , vol.162 , Issue.15 , pp. 1682-1688
    • Heiat, A.1    Gross, C.P.2    Krumholz, H.M.3
  • 9
    • 34547837711 scopus 로고    scopus 로고
    • Characteristics, treatments, and outcomes of patients with preserved systolic function hospitalized for heart failure: A report from the OPTIMIZE-HF Registry
    • 17707182
    • Fonarow GC, Stough WG, Abraham WT,; OPTIMIZE-HF Investigators and Hospitals. Characteristics, treatments, and outcomes of patients with preserved systolic function hospitalized for heart failure: a report from the OPTIMIZE-HF Registry. J Am Coll Cardiol. 2007; 50 (8): 768-777. 17707182
    • (2007) J Am Coll Cardiol , vol.50 , Issue.8 , pp. 768-777
    • Fonarow, G.C.1    Stough, W.G.2    Abraham, W.T.3
  • 10
    • 84863614614 scopus 로고    scopus 로고
    • Trends in patients hospitalized with heart failure and preserved left ventricular ejection fraction: Prevalence, therapies, and outcomes
    • 22615345
    • Steinberg BA, Zhao X, Heidenreich PA,; Get With the Guidelines Scientific Advisory Committee and Investigators. Trends in patients hospitalized with heart failure and preserved left ventricular ejection fraction: prevalence, therapies, and outcomes. Circulation. 2012; 126 (1): 65-75. 22615345
    • (2012) Circulation , vol.126 , Issue.1 , pp. 65-75
    • Steinberg, B.A.1    Zhao, X.2    Heidenreich, P.A.3
  • 11
    • 29344440492 scopus 로고    scopus 로고
    • Clinical presentation, management, and in-hospital outcomes of patients admitted with acute decompensated heart failure with preserved systolic function: A report from the Acute Decompensated Heart Failure National Registry (ADHERE) Database
    • 16386668
    • Yancy CW, Lopatin M, Stevenson LW, De Marco T, Fonarow GC, Committee ASA; ADHERE Scientific Advisory Committee and Investigators. Clinical presentation, management, and in-hospital outcomes of patients admitted with acute decompensated heart failure with preserved systolic function: a report from the Acute Decompensated Heart Failure National Registry (ADHERE) Database. J Am Coll Cardiol. 2006; 47 (1): 76-84. 16386668
    • (2006) J Am Coll Cardiol , vol.47 , Issue.1 , pp. 76-84
    • Yancy, C.W.1    Lopatin, M.2    Stevenson, L.W.3    De Marco, T.4    Fonarow, G.C.5
  • 12
    • 77955466458 scopus 로고    scopus 로고
    • Improving evidence-based care for heart failure in outpatient cardiology practices: Primary results of the Registry to Improve the Use of Evidence-Based Heart Failure Therapies in the Outpatient Setting (IMPROVE HF)
    • 20660805
    • Fonarow GC, Albert NM, Curtis AB, Improving evidence-based care for heart failure in outpatient cardiology practices: primary results of the Registry to Improve the Use of Evidence-Based Heart Failure Therapies in the Outpatient Setting (IMPROVE HF). Circulation. 2010; 122 (6): 585-596. 20660805
    • (2010) Circulation , vol.122 , Issue.6 , pp. 585-596
    • Fonarow, G.C.1    Albert, N.M.2    Curtis, A.B.3
  • 13
    • 85053919652 scopus 로고    scopus 로고
    • Health status variation across practices in outpatients with heart failure: Insights from the CHAMP-HF (Change the Management of Patients with Heart Failure) Registry
    • 29627798
    • Khariton Y, Hernandez AF, Fonarow GC, Health status variation across practices in outpatients with heart failure: insights from the CHAMP-HF (Change the Management of Patients With Heart Failure) Registry. Circ Cardiovasc Qual Outcomes. 2018; 11 (4): e004668. 29627798
    • (2018) Circ Cardiovasc Qual Outcomes , vol.11 , Issue.4 , pp. e004668
    • Khariton, Y.1    Hernandez, A.F.2    Fonarow, G.C.3
  • 14
    • 84930695962 scopus 로고    scopus 로고
    • A contemporary appraisal of the heart failure epidemic in Olmsted County, Minnesota, 2000 to 2010
    • 25895156
    • Gerber Y, Weston SA, Redfield MM, A contemporary appraisal of the heart failure epidemic in Olmsted County, Minnesota, 2000 to 2010. JAMA Intern Med. 2015; 175 (6): 996-1004. 25895156
    • (2015) JAMA Intern Med , vol.175 , Issue.6 , pp. 996-1004
    • Gerber, Y.1    Weston, S.A.2    Redfield, M.M.3
  • 15
    • 0037108639 scopus 로고    scopus 로고
    • Outcome of congestive heart failure in elderly persons: Influence of left ventricular systolic function: The Cardiovascular Health Study
    • 12379062
    • Gottdiener JS, McClelland RL, Marshall R, Outcome of congestive heart failure in elderly persons: influence of left ventricular systolic function: the Cardiovascular Health Study. Ann Intern Med. 2002; 137 (8): 631-639. 12379062
    • (2002) Ann Intern Med , vol.137 , Issue.8 , pp. 631-639
    • Gottdiener, J.S.1    McClelland, R.L.2    Marshall, R.3
  • 16
    • 67649497912 scopus 로고    scopus 로고
    • Relation of disease pathogenesis and risk factors to heart failure with preserved or reduced ejection fraction: Insights from the framingham heart study of the national heart, lung, and blood institute
    • 19506115
    • Lee DS, Gona P, Vasan RS, Relation of disease pathogenesis and risk factors to heart failure with preserved or reduced ejection fraction: insights from the framingham heart study of the national heart, lung, and blood institute. Circulation. 2009; 119 (24): 3070-3077. 19506115
    • (2009) Circulation , vol.119 , Issue.24 , pp. 3070-3077
    • Lee, D.S.1    Gona, P.2    Vasan, R.S.3
  • 17
    • 84962623053 scopus 로고    scopus 로고
    • Impact of race, ethnicity, and multimodality biomarkers on the incidence of new-onset heart failure with preserved ejection fraction (from the Multi-Ethnic Study of Atherosclerosis)
    • 27001449
    • Silverman MG, Patel B, Blankstein R, Impact of race, ethnicity, and multimodality biomarkers on the incidence of new-onset heart failure with preserved ejection fraction (from the Multi-Ethnic Study of Atherosclerosis). Am J Cardiol. 2016; 117 (9): 1474-1481. 27001449
    • (2016) Am J Cardiol , vol.117 , Issue.9 , pp. 1474-1481
    • Silverman, M.G.1    Patel, B.2    Blankstein, R.3
  • 18
    • 14844291419 scopus 로고    scopus 로고
    • Characteristics and outcomes of patients hospitalized for heart failure in the United States: Rationale, design, and preliminary observations from the first 100,000 cases in the Acute Decompensated Heart Failure National Registry (ADHERE)
    • 15846257
    • Adams KF Jr, Fonarow GC, Emerman CL,; ADHERE Scientific Advisory Committee and Investigators. Characteristics and outcomes of patients hospitalized for heart failure in the United States: rationale, design, and preliminary observations from the first 100,000 cases in the Acute Decompensated Heart Failure National Registry (ADHERE). Am Heart J. 2005; 149 (2): 209-216. 15846257
    • (2005) Am Heart J , vol.149 , Issue.2 , pp. 209-216
    • Adams, K.F.1    Fonarow, G.C.2    Emerman, C.L.3
  • 19
    • 85019631315 scopus 로고    scopus 로고
    • Assessing the eligibility criteria in phase iii randomized controlled trials of drug therapy in heart failure with preserved ejection fraction: The critical play-off between a "pure" patient phenotype and the generalizability of trial findings
    • 28434933
    • Patel HC, Hayward C, Dungu JN, Assessing the eligibility criteria in phase iii randomized controlled trials of drug therapy in heart failure with preserved ejection fraction: the critical play-off between a "pure" patient phenotype and the generalizability of trial findings. J Card Fail. 2017; 23 (7): 517-524. 28434933
    • (2017) J Card Fail , vol.23 , Issue.7 , pp. 517-524
    • Patel, H.C.1    Hayward, C.2    Dungu, J.N.3
  • 20
    • 85039981232 scopus 로고    scopus 로고
    • Representation of black patients in randomized clinical trials of heart failure with reduced ejection fraction
    • 29447783
    • Sullivan LT, Randolph T, Merrill P, Representation of black patients in randomized clinical trials of heart failure with reduced ejection fraction. Am Heart J. 2018; 197: 43-52. 29447783
    • (2018) Am Heart J , vol.197 , pp. 43-52
    • Sullivan, L.T.1    Randolph, T.2    Merrill, P.3
  • 22
    • 84883824600 scopus 로고    scopus 로고
    • Genome-wide association analysis of blood-pressure traits in African-ancestry individuals reveals common associated genes in African and non-African populations
    • 23972371
    • Franceschini N, Fox E, Zhang Z,; Asian Genetic Epidemiology Network Consortium. Genome-wide association analysis of blood-pressure traits in African-ancestry individuals reveals common associated genes in African and non-African populations. Am J Hum Genet. 2013; 93 (3): 545-554. 23972371
    • (2013) Am J Hum Genet , vol.93 , Issue.3 , pp. 545-554
    • Franceschini, N.1    Fox, E.2    Zhang, Z.3
  • 23
    • 79953726293 scopus 로고    scopus 로고
    • Association of race/ethnicity with clinical risk factors, quality of care, and acute outcomes in patients hospitalized with heart failure
    • 21473975
    • Thomas KL, Hernandez AF, Dai D, Association of race/ethnicity with clinical risk factors, quality of care, and acute outcomes in patients hospitalized with heart failure. Am Heart J. 2011; 161 (4): 746-754. 21473975
    • (2011) Am Heart J , vol.161 , Issue.4 , pp. 746-754
    • Thomas, K.L.1    Hernandez, A.F.2    Dai, D.3
  • 24
    • 77953395570 scopus 로고    scopus 로고
    • Representation of women in randomized clinical trials of cardiovascular disease prevention
    • 20160159
    • Melloni C, Berger JS, Wang TY, Representation of women in randomized clinical trials of cardiovascular disease prevention. Circ Cardiovasc Qual Outcomes. 2010; 3 (2): 135-142. 20160159
    • (2010) Circ Cardiovasc Qual Outcomes , vol.3 , Issue.2 , pp. 135-142
    • Melloni, C.1    Berger, J.S.2    Wang, T.Y.3
  • 25
    • 0034680053 scopus 로고    scopus 로고
    • Enrollment of women in cardiovascular clinical trials funded by the National Heart, Lung, and Blood Institute
    • 10944565
    • Harris DJ, Douglas PS. Enrollment of women in cardiovascular clinical trials funded by the National Heart, Lung, and Blood Institute. N Engl J Med. 2000; 343 (7): 475-480. 10944565
    • (2000) N Engl J Med , vol.343 , Issue.7 , pp. 475-480
    • Harris, D.J.1    Douglas, P.S.2
  • 26
    • 84879786274 scopus 로고    scopus 로고
    • Reporting and representation of ethnic minorities in cardiovascular trials: A systematic review
    • 23816021
    • Zhang T, Tsang W, Wijeysundera HC, Ko DT. Reporting and representation of ethnic minorities in cardiovascular trials: a systematic review. Am Heart J. 2013; 166 (1): 52-57. 23816021
    • (2013) Am Heart J , vol.166 , Issue.1 , pp. 52-57
    • Zhang, T.1    Tsang, W.2    Wijeysundera, H.C.3    Ko, D.T.4
  • 27
    • 85047514448 scopus 로고    scopus 로고
    • Globalization of heart failure clinical trials: A systematic review of 305 trials conducted over 16 years
    • 29314445
    • Vaduganathan M, Samman Tahhan A, Greene SJ, Okafor M, Kumar S, Butler J. Globalization of heart failure clinical trials: a systematic review of 305 trials conducted over 16 years. Eur J Heart Fail. 2018; 20 (6): 1068-1071. 29314445
    • (2018) Eur J Heart Fail , vol.20 , Issue.6 , pp. 1068-1071
    • Vaduganathan, M.1    Samman Tahhan, A.2    Greene, S.J.3    Okafor, M.4    Kumar, S.5    Butler, J.6
  • 28
    • 85040644578 scopus 로고    scopus 로고
    • Evolving landscape of clinical trials in heart failure: Patient populations, endpoint selection, and regions of enrollment
    • 29350324
    • Samman Tahhan A, Vaduganathan M, Greene SJ, Okafor M, Kumar S, Butler J. Evolving landscape of clinical trials in heart failure: patient populations, endpoint selection, and regions of enrollment. Curr Heart Fail Rep. 2018; 15 (1): 10-16. 29350324
    • (2018) Curr Heart Fail Rep , vol.15 , Issue.1 , pp. 10-16
    • Samman Tahhan, A.1    Vaduganathan, M.2    Greene, S.J.3    Okafor, M.4    Kumar, S.5    Butler, J.6
  • 29
    • 84966565299 scopus 로고    scopus 로고
    • Recruitment strategies and challenges in a large intervention trial: Systolic Blood Pressure Intervention Trial
    • 26911833
    • Ramsey TM, Snyder JK, Lovato LC,; SPRINT Study Research Group. Recruitment strategies and challenges in a large intervention trial: Systolic Blood Pressure Intervention Trial. Clin Trials. 2016; 13 (3): 319-330. 26911833
    • (2016) Clin Trials , vol.13 , Issue.3 , pp. 319-330
    • Ramsey, T.M.1    Snyder, J.K.2    Lovato, L.C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.