The changing landscape of naloxone availability in the United States, 2011 – 2017

Drug and Alcohol Dependence

Volumn 191, Issue , 2018, Pages 361-364

  Freeman, Patricia R ^a   Hankosky, Emily R ^a   Lofwall, Michelle R ^b   Talbert, Jeffery C ^a  

^a University of Kentucky   (United States)

^b UNIVERSITY OF KENTUCKY   (United States)

Author keywords

Naloxone; Opioid overdose; Pharmacy; Policy; Third party prescribing

Indexed keywords

NALOXONE; NARCOTIC ANALGESIC AGENT; NARCOTIC ANTAGONIST;

ARTICLE; DRUG OVERDOSE; HEALTH CARE ACCESS; HEALTH CARE AVAILABILITY; HUMAN; MORTALITY RATE; OPIATE ADDICTION; PRESCRIPTION; PRIORITY JOURNAL; UNITED STATES;

ANALGESICS, OPIOID; DRUG OVERDOSE; DRUG PRESCRIPTIONS; HUMANS; NALOXONE; NARCOTIC ANTAGONISTS; OPIOID-RELATED DISORDERS; UNITED STATES;

EID: 85052862248     PISSN: 03768716     EISSN: 18790046     Source Type: Journal    
DOI: 10.1016/j.drugalcdep.2018.07.017     Document Type: Article

References (19)

1. Adams, J.M., Increasing naloxone awareness and use: the role of health care practitioners. JAMA 319 (2018), 2073–2074.
2. Centers for Disease Control and Prevention (CDC), NCHS Data Brief, Number 294. Drug Overdose Deaths in the United States, 1999-2016. 2017 Available at (Accessed 16 May 2018) https://www.cdc.gov/nchs/data/databriefs/db294_table.pdf#page=4.
3. Centers for Disease Control and Prevention (CDC), National Center for Health Statistics, About Multiple Cause of Death 1999–2016. 2017 Available at (Accessed 16 May 2018) http://wonder.cdc.gov/mcd-icd10.html.
4. Commonwealth of Virginia, Office of the Governor, Opioid Addiction Crisis Declared a Public Health Emergency in Virginia. 2016 [Press Release]. Available at (Accessed 16 May 2018) https://governor.virginia.gov/newsroom/newsarticle?articleId=18348.
5. Davis, C.S., Carr, D., Legal changes to increase access to naloxone for opioid overdose reversal in the United States. Drug Alcohol Depend. 157 (2015), 112–120.
6. Davis, C.S., Carr, D., State legal innovations to encourage naloxone dispensing. J. Am. Pharm. Assoc. 57 (2017), S180–S184.
7. Davis, C.S., Walley, A.Y., Bridger, C.M., Lessons learned from the expansion of naloxone access in Massachusetts and North Carolina. J. Law Med. Ethics 43:Suppl (2015), 19–22.
8. Dowell, D., Haegerich, T.M., Chou, R., CDC guideline for prescribing opioids for chronic pain — United States, 2016. MMWR Morb. Mortal. Wkly. Rep. Recomm. Rep. 65:RR-1 (2016), 1–49, 10.15585/mmwr.rr6501e1.
9. Fairbairn, N., Coffin, P.O., Walley, A.Y., Naloxone for heroin, prescription opioid, and illicitly made fentanyl overdoses: challenges and innovations responding to a dynamic epidemic. Int. J. Drug Policy 46 (2017), 172–179.
10. Gupta, R., Shah, N.D., Ross, J.S., The rising price of naloxone—risks to efforts to stem overdose deaths. N. Engl. J. Med. 375 (2016), 2213–2215.
11. Jones, C.M., Lurie, P.G., Compton, W.M., Increase in naloxone prescriptions dispensed in US retail pharmacies since 2013. Am. J. Public Health 106 (2016), 689–690.
12. Kerensky, T., Walley, A.Y., Opioid overdose prevention and naloxone rescue kits: what we know and what we don't know. Addict. Sci. Clin. Pract., 12, 2017, 4, 10.1186/s13722-016-0068-3.
13. Lambdin, B.H., Davis, C.S., Wheeler, E., Tueller, S., Kral, A.H., Naloxone laws facilitate the establishment of overdose education and naloxone distribution programs in the United States. Drug Alcohol Depend. 188 (2018), 370–376.
14. Pauly, N.J., Slavova, S., Delcher, C., Freeman, P.R., Talbert, J., Features of prescription drug monitoring programs associated with reduced rates of prescription opioid-related poisonings. Drug Alcohol Depend. 184 (2018), 26–32.
15. Vermont General Assembly, 18 V.S.A. 4240. Prevention and Treatment of Opioid-related Overdoses. 2013 (Accessed 23 May 2018) https://legislature.vermont.gov/statutes/section/18/084/04240.
16. Virginia Register of Regulations, 2017 Vol. 33 Iss. 16 (Emergency Regulation) 18VAC85-21, 2017. Regulations Governing Prescribing of Opioids and Buprenorphine Available at: http://register.dls.virginia.gov/details.aspx?id=6295 (Accessed 16 May, 2018).
17. Walley, A.Y., Xuan, Z., Hackman, H.H., et al. Opioid overdose rates and implementation of overdose education and nasal naloxone distribution in Massachusetts: interrupted time series analysis. BMJ, 346, 2013, f174.
18. Wheeler, E., Jones, T.S., Gilbert, M.K., Davidson, P.J., Centers for Disease Control and Prevention, 2015. Opioid overdose prevention programs providing naloxone to laypersons – United States. MMWR Morb. Mortal. Wkly. Rep. 64 (2014), 631–635.
19. Xu, J., Davis, C.S., Cruz, M., Lurie, P., State naloxone access laws are associated with an increase in the number of naloxone prescriptions dispensed in retail pharmacies. Drug Alcohol Depend. 189 (2018), 37–41.