Alterations in intracerebral hemorrhage-induced brain injury in the iron deficient rat

Acta Neurochirurgica, Supplementum

Volumn , Issue 96, 2006, Pages 183-187

  Shao, J ^a   Xi, G ^b   Hua, Y ^b   Schallert, T ^b,c   Felt, B T ^d  

^a ZHEJIANG UNIVERSITY   (China)

^b UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^c UNIVERSITY OF TEXAS AT AUSTIN   (United States)

^d UNIVERSITY OF MICHIGAN   (United States)

Author keywords

behavior; edema; Intracerebral hemorrhage; iron deficiency anemia; transferrin

Indexed keywords

IRON;

ANIMAL; ARTICLE; BRAIN; BRAIN HEMORRHAGE; BRAIN INJURY; DISEASE MODEL; IRON DEFICIENCY ANEMIA; MALE; MENTAL DISEASE; METABOLISM; PATHOPHYSIOLOGY; RAT; SPRAGUE DAWLEY RAT;

ANEMIA, IRON-DEFICIENCY; ANIMALS; BRAIN; BRAIN INJURIES; CEREBRAL HEMORRHAGE; DISEASE MODELS, ANIMAL; IRON; MALE; MENTAL DISORDERS; RATS; RATS, SPRAGUE-DAWLEY;

EID: 85052610313     PISSN: 00651419     EISSN: None     Source Type: Book Series    
DOI: 10.1007/3-211-30714-1_40     Document Type: Article

References (23)

1. Baynes RD, Bothwell TH (1990) Iron deficiency. Annu Rev Nutr 10:133-148
2. Beard JL, Connor JR, Jones BC (1993) Iron in the brain. Nutr Rev 51:157-170
3. Brittenham G (1979) Spectrophotometric plasma iron determination from fingerpuncture specimens. Clin Chim Acta 91:203-211
4. Chiueh CC (2001) Iron overload, oxidative stress, and axonal dystrophy in brain disorders. Pediatr Neurol 25:138-147
5. Erikson K, Pinero DJ, Connor JR, Beard JL (1997) Regional brain iron, ferritin and transferrin concentrations during iron deficiency and iron repletion in developing rats. J Nutr 127:2030-2038
6. Felt BT, Lozoff B (1996) Brain iron and behavior of rats are not normalized by treatment of iron deficiency anemia during early development. J Nutr 126:693-701
7. Felt BT, Schallert T, Shao J, Liu Y, Li X, Barks JD (2002) Early appearance of functional deficits after neonatal excitotoxic and hypoxic-ischemic injury: fragile recovery after development and role of the NMDA receptor. Dev Neurosci 24:418-425
8. Han J, Day JR, Connor JR, Beard JL (2003) Gene expression of transferrin and transferrin receptor in brains of control vs irondeficient rats. Nutr Neurosci 6:1-10
9. Hua Y, Schallert T, Keep RF, Wu J, Hoff JT, Xi G (2002) Behavioral tests after intracerebral hemorrhage in the rat. Stroke 33:2478-2484
10. Huang FP, Xi G, Keep RF, Hua Y, Nemoianu A, Hoff JT (2002) Brain edema after experimental intracerebral hemorrhage: role of hemoglobin degradation products. J Neurosurg 96:287-293
11. Kase CS, Caplan LR (1994) Intracerebral Hemorrhage. Butterworth- Heinemann, Boston
12. Koeppen AH, Dickson AC, McEvoy JA (1995) The cellular reactions to experimental intracerebral hemorrhage. J Neurol Sci 134 Suppl: 102-112
13. Lee KR, Colon GP, Betz AL, Keep RF, Kim S, Hoff JT (1996) Edema from intracerebral hemorrhage: the role of thrombin. J Neurosurg 84:91-96
14. Masada T, Hua Y, Xi G, Yang GY, Hoff JT, Keep RF (2001) Attenuation of intracerebral hemorrhage and thrombin-induced brain edema by overexpression of interleukin-1 receptor antagonist. J Neurosurg 95:680-686
15. Nakamura T, Keep RF, Hua Y, Schallert T, Hoff JT, Xi G (2004) Deferoxamine-induced attenuation of brain edema and neurological deficits in a rat model of intracerebral hemorrhage. J Neurosurg 100:672-678
16. Rao R, de Ungria M, Sullivan D, Wu P, Wobken JD, Nelson CA, Georgieff MK (1999) Perinatal brain iron deficiency increases the vulnerability of rat hippocampus to hypoxic ischemic insult. J Nutr 129:199-206
17. Schallert T, Woodlee MT (2003) Brain-dependent movements and cerebral-spinal connections: key targets of cellular and behavioral enrichment in CNS injury models. J Rehabil Res Dev 40 (4 Suppl 1):9-17
18. Shao J, Xi G, Hua Y, Schallert T, Felt B (2005) Intracerebral hemorrhage in the iron deficient rat. Stroke 36:660-664
19. Stoltzfus RJ (2001) Defining iron-deficiency anemia in public health terms: A time for reflection. J Nutr 131:565S-567S
20. Wu J, Hua Y, Keep RF, Schallert T, Hoff JT, Xi G (2002) Oxidative brain injury from extravasated erythrocytes after intracerebral hemorrhage. Brain Res 953:45-52
21. Wu J, Hua Y, Keep RF, Nakamura T, Hoff JT, Xi G (2003) Iron and iron-handling proteins in the brain after intracerebral hemorrhage. Stroke 34:2964-2969
22. Xi G, Keep RF, Hoff JT (1998) Erythrocytes and delayed brain edema formation following intracerebral hemorrhage in rats. J Neurosurg 89:991-996
23. Xi G, Wagner KR, Keep RF, Hua Y, de Courten-Myers GM, Broderick JP, Brott TG, Hoff JT, Muizelaar JP (1998) Role of blood clot formation on early edema development after experimental intracerebral hemorrhage. Stroke 29:2580-2586