Restitution of ischemic injuries in penumbra of cerebral cortex after temporary ischemia

Acta Neurochirurgica, Supplementum

Volumn , Issue 96, 2006, Pages 239-243

  Ito, U ^a,c   Kawakami, E ^a   Nagasao, J ^a   Kuroiwa, T ^b   Nakano, I ^c   Oyanagi, K ^a  

^a TOKYO METROPOLITAN INSTITUTE OF MEDICAL SCIENCE   (Japan)

^b TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

^c JICHI MEDICAL UNIVERSITY   (Japan)

Author keywords

cerebral ischemia; Maturation phenomenon; neuronal remodeling

Indexed keywords

ANIMAL; APOPTOSIS; ARTICLE; ASTROCYTE; BRAIN CORTEX; BRAIN EDEMA; BRAIN ISCHEMIA; CELL CULTURE; GERBIL; NERVE CELL; NERVE FIBER; NERVE REGENERATION; NEURITE; PATHOLOGY; REPERFUSION INJURY; ULTRASTRUCTURE; VASCULARIZATION;

ANIMALS; APOPTOSIS; ASTROCYTES; AXONS; BRAIN EDEMA; BRAIN ISCHEMIA; CELLS, CULTURED; CEREBRAL CORTEX; GERBILLINAE; NERVE REGENERATION; NEURITES; NEURONS; REPERFUSION INJURY;

EID: 85052609645     PISSN: 00651419     EISSN: None     Source Type: Book Series    
DOI: 10.1007/3-211-30714-1_51     Document Type: Article

References (22)

1. Crepel V, Epsztein J, Ben-Ari Y (2003) Ischemia induces shortand long-term remodeling of synaptic activity in the hippocampus. J Cell Mol Med 7:401-407
2. Frost SB, Barbay S, Friel KM, Plautz EJ, Nudo RJ (2003) Reorganization of remote cortical regions after ischemic brain injury: a potential substrate for stroke recovery. J Neurophysiol 89:3205-3214
3. Graham DI, Lantos PL (2002) Greenfield's neuropathology illustrated. Oxford University Press, London, pp 230-280
4. Hakamata Y, Hanyu S, Kuroiwa T, Ito U (1997) Brain edema associated with progressive selective neuronal death or impending infarction in the cerebral cortex. Acta Neurochir [Suppl] 70:20-22 (Pubitemid 127502039)
5. Hanyu S, Ito U, Hakamata Y, Nakano I (1997) Topographical analysis of cortical neuronal loss associated with disseminated selective neuronal necrosis and infarction after repeated ischemia. Brain Res 767:154-157
6. Ito U, Spatz M, Walker JT Jr, Klatzo I (1975) Experimental cerebral ischemia in mongolian gerbils. I. Light microscopic observations. Acta Neuropathol Berl 32:209-223
7. Ito U, Hanyu S, Hakamata Y, Nakamura M, Arima K (1997) Ultrastructure of astrocytes associated with selective neuronal death of cerebral cortex after repeated ischemia. Acta Neurochir [Suppl] 70:46-49 (Pubitemid 127502047)
8. Ito U, Hanyu S, Hakamata Y, Arima K, Oyanagi K, Kuroiwa T, Nakano I (1999) Temporal profile of cortical injury following ischemic insult just-below and at the threshold level for induction of infarction - light and electron microscopic study. In: Ito U, Fieschi C, Orzi F, Kuroiwa T, Klatzo I (eds) Maturation phenomenon in cerebral ischemia III. Springer, Berlin New York, pp 227-235
9. Ito U, Kuroiwa T, Hanyu S, Hakamata Y, Nakano I, Oyanagi K (2000) Ultrastructural behavior of astrocytes to singly dying cortical neurons. In: Krieglstein J, Klumpp S (eds) Pharmacology of cerebral ischemia. Medpharm Science Publications, Stuttgart, pp 285-291
10. Ito U, Kuroiwa T, Hakamata Y, Kawakami E, Nakano I, Oyana K (2002) How are ischemically dying eosinophilic neurons scavenged in the penumbra? An ultrastructural study. In: Krieglstein J, Klumpp S (eds) Pharmacology of cerebral ischemia. Medpharm Science Publication, Stuttgart, pp 261-265
11. Ito U, Kuroiwa T, Hanyu S, Hakamata Y, Kawakami E, Nakano I, Oyanagi K (2003) Temporal profile of experimental ischemic edema after threshold amount of insult to induce infarction - ultrastructure, gravimetry and Evans' blue extravasation. Acta Neurochir [Suppl] 86:131-135
12. Ito U, Kuroiwa T, Hanyu S, Hakamata Y, Kawakami E, Nakano I, Oyanagi K (2003) Ultrastructural temporal profile of the dying neuron and surrounding astrocytes in the ischemic penumbra: apoptosis or necrosis? In: Buchan AM, Ito U, Colbourne F, Kuroiwa T, Klatzo I (eds) Maturation phenomenon in cerebral ischemia V. Springer, Berlin Heidelberg, pp 189-196
13. Jourdain P, Nikonenko I, Alberi S, Muller D (2002) Remodeling of hippocampal synaptic networks by a brief anoxiahypoglycemia. J Neurosci 22:3108-3116
14. Kalmar B, Kittel A, Lemmens R, Kornyei Z, Madarasz E (2001) Cultured astrocytes react to LPS with increased cyclooxygenase activity and phagocytosis. Neurochem Int 38:453-461
15. Kirino T, Tamura A, Sano K (1984) Delayed neuronal death in the rat hippocampus following transient forebrain ischemia. Acta Neuropathol Berl 64:139-147 (Pubitemid 14096059)
16. Lemkey-Johnston N, Butler V, Reynolds WA (1976) Glial changes in the progress of a chemical lesion. An electron microscopic study. J Comp Neurol 167:481-501
17. Nudo RJ, Larson D, Plautz EJ, Friel KM, Barbay S, Frost SB (2003) A squirrel monkey model of poststroke motor recovery. ILAR J 44:161-174
18. Ohno K, Ito U, Inaba Y (1984) Regional cerebral blood flow and stroke index after left carotid artery ligation in the conscious gerbil. Brain Res 297:151-157
19. Rosenblum WI (1997) Histopathologic clues to the pathways of neuronal death following ischemia/hypoxia. J Neurotrauma 14:313-326
20. Stroemer RP, Kent TA, Hulsebosch CE (1995) Neocortical neural sprouting, synaptogenesis, and behavioral recovery after neocortical infarction in rats. Stroke 26:2135-2144
21. von Lubitz DK, Diemer NH (1983) Cerebral ischemia in the rat: ultrastructural and morphometric analysis of synapses in stratum radiatum of the hippocampal CA-1 region. Acta Neuropathol (Berl) 61:52-60
22. Weibel ER (1963) Morphometry of the human lung. Springer, Berlin, pp 19-20