Temporal profile of experimental ischemic edema after threshold amount of insult to induce infarction - Ultrastructure, gravimetry and Evans' blue extravasation

Acta Neurochirurgica, Supplementum

Volumn , Issue 86, 2003, Pages 131-135

  Ito, U ^a,c   Kuroiwa, T ^b   Hanyu, S ^c   Hakamata, Y ^c   Kawakami, E ^a   Nakano, I ^c   Oyanagi, K ^a  

^a Department of Neuropathology   (Japan)

^b Tokyo Medical and Dental University ^*  (Japan)

^c JICHI MEDICAL UNIVERSITY   (Japan)

Author keywords

Astrocytic mitochondria; Cerebral ischemia; Cyto necrotic edema; Cyto reactive edema; Cytotoxic edema; Disseminated selective neuronal necrosis (DSNN); Extracellular space; Glycogen granules; Infarction; Intracellular space; Ischemic brain edema; Penumbra; Vasogenic edema

Indexed keywords

COLORING AGENT; EVANS BLUE;

ANIMAL; ARTICLE; BRAIN; BRAIN EDEMA; BRAIN INFARCTION; BRAIN ISCHEMIA; ELECTRON MICROSCOPY; GERBIL; METABOLISM; NECROSIS; PATHOLOGY; TIME; ULTRASTRUCTURE;

ANIMALS; BRAIN; BRAIN EDEMA; BRAIN ISCHEMIA; CEREBRAL INFARCTION; COLORING AGENTS; EVANS BLUE; GERBILLINAE; MICROSCOPY, ELECTRON; NECROSIS; TIME FACTORS;

EID: 1442279300     PISSN: 00651419     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-3-7091-0651-8_28     Document Type: Article

References (22)

1. Coles JA (1995) Glial cells and the supply of substrates of energy metabolism to neurons, Neuroglia. In: Kettenmann H, Ransom B (eds), Oxford University Press, New York Oxford, pp 793-804
2. Hakamata Y, Hanyu S, Kuroiwa T, Ito U (1997) Brain edema associated with progressive selective neuronal death or impending infarction in the cerebral cortex. Acta Neurochir (Wien) [Suppl] 70: 20-22
3. Hamprecht B, Dringen R (1995) Energy metabolism. Neuroglia. In: Kettenmann H, Ransom B (eds), Oxford University Press, New York Oxford, pp 473-487
4. Hanyu S, Ito U, Hakamata Y, Yoshida M (1995) Transition from ischemic neuronal necrosis to infarction in repeated ischemia. Brain Res 686:44-48
5. Ito U, Spatz M, Walker J Jr, Klatzo I (1975) Experimental cerebral ischemia in mongolian gerbils. I. Light microscopic observations. Acta Neuropathol 32(3): 209-223
6. Ito U, Ohno K, Nakamura R, Suganuma F, Inaba Y (1970) Brain edema during ischemia and after restoration of blood flow. Measurement of water, sodium, potassium content and plasma protein permeability. Stroke 10: 542-547
7. Ito U, Hanyu S, Hakamata Y, Nakamura M, Arima K (1997) Ultrastructure of astrocytes associated with selective neuronal death of cerebral cortex after rejieated ischemia. Acta Neurochir (Wien) [Suppl] 70:46-49
8. Ito U, Hanyu S, Hakamata Y, Arima K, Oyanagi K, Kuroiwa T, Nakano I (1999) Temporal profile of cortical injury following ischemic insult just-below and at the threshold level for induction of infarction - light and electron microscopic study. Maturation phenomenon in cerebral ischemia III. Springer, Berlin Heidelberg New York Tokyo, pp 227-235
9. Ito U, Kuroiwa T, Hanyu S, Hakamata Y, Ito S, Nakano I, Oyanagi K (2000) Ultrastructure and morphometry of astroglial mitochondria following temporary ischemia. Maturation phenomenon in cerebral ischemia IV. In: Bazan NG, Ito U, Marcheselli VL, Kuroiwa T, Klatzo IE (eds). Springer, Berlin Heidelberg New York Tokyo, pp 253-259
10. Katzmann R, Classen CR, Klatzo I, Meyer JS, Waltz AG (1977) Report of joint committee for stroke resources IV. Brain edema in stroke. Study group on brain edema in stroke. Stroke 8: 513-540
11. Kempski O, Volk C (1996) Glial protection against neuronal damage. Maturation phenomenon in cerebral ischemia II. Springer, Berlin Heidelberg New York Tokyo
12. + medium causes inhibition of glutamate and aspartate uptake and increases their release. J Cereb Blood Flow Metab 15(3): 409-416
13. Kraig RP, Lascola CD, Caggiano A (1995) Glial response to brain ischemia. Neuroglia. In: Kettenmann H, Ransom B (eds), O.xford University Press, New York Oxford, pp 964-976
14. Kuroiwa T, Mies G, Hakamata Y, Hanyu S, Okeda R, Ito U (1999) Mitochondrial dysfunction and maturation phenomenon in ischemic gerbil cortex. Maturation phenomenon in cerebral ischemia III ed. In: Ito U, Orzi F, Kuroiwa T, Fieschi C, Klatzo IE (eds). Springer, Berlin Heidelberg New York Tokyo, pp 237-241
15. Kuroiwa T, Mies G, Hermann D, Hakamata Y, Hanyu S, Ito U (2000) Regional differences in the rate of energy impairment after threshold level ischemia for induction of cerebral infarction in gerbils. Acta Neuropathol 100: 587-594
16. Martin DL (1995) The role of glia in the inactivation of neurotransmitters. Neuroglia. In: Kettenmann H, Ransom B (eds), Oxford University Press, New York Oxford, pp 732-745
17. Newman EA (1995) Glial cell regulation of extracellular potassium. Neuroglia. In: Kettenmann H, Ransom B (eds), Oxford University Press, New York Oxford, pp 717-731
18. Noble LJ, Hall JJ, Chen S, Chan PH (1992) Morphologic changes in cultured astrocytes after exposure to glutamate. J Neurotrauma 9: 255-267
19. Rosenberg GA, Aizeman E (1989) Hundred-fold increase in neuronal vulnerability to glultamate toxicity in astrocyte-poor cultures of rat cerebral cortex. Neuroscience(Lett) 103:162-168
20. Siesjo BK (1992) Pathophysiology and treatment of focal cerebral ischemia. Part I: pathophysiology. J Neurosurg 77:169-184
21. Sonnewald U, Hertz L, Schousboe A (1998) Mitochondrial heterogeneity in the brain at the cellular level. J Cereb Blood Flow Metab 18(3): 231-237
22. Staub F, Baethmann A, Peters J, Weight H, Kempski O (1990) Effects of lactacidosis on glial cell volume and viability. J Cereb Blood Flow Metab 10: 866-876