Paradoxical association of smoking with in-hospital mortality among patients admitted with acute ischemic stroke

Journal of the American Heart Association

Volumn 2, Issue 3, 2013, Pages

  Ali, Syed F ^a   Smith, Eric E ^b   Bhatt, Deepak L ^c   Fonarow, Gregg C ^d   Schwamm, Lee H ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b UNIVERSITY OF CALGARY   (Canada)

^c BRIGHAM AND WOMEN S HOSPITAL   (United States)

^d UCLA MEDICAL CENTER   (United States)

Author keywords

Cerebrovascular disease; Embolic stroke; Mortality; Thrombolysis

Indexed keywords

ANTICOAGULANT AGENT; TISSUE PLASMINOGEN ACTIVATOR;

ADULT; AGE; AGED; ARTICLE; BRAIN ISCHEMIA; CONTROLLED STUDY; CORONARY ARTERY DISEASE; DEEP VEIN THROMBOSIS; DIABETES MELLITUS; DISEASE ASSOCIATION; DISEASE REGISTRY; DYSPHAGIA; ETHNICITY; FEMALE; GENDER; HEART ATRIUM FIBRILLATION; HOSPITAL ADMISSION; HOSPITAL PATIENT; HUMAN; HYPERLIPIDEMIA; HYPERTENSION; MAJOR CLINICAL STUDY; MALE; MORTALITY; PATIENT COMPLIANCE; PRACTICE GUIDELINE; PRIORITY JOURNAL; SMOKING; THROMBOSIS PREVENTION; CEREBROVASCULAR ACCIDENT; COMPLICATION; MIDDLE AGED; RETROSPECTIVE STUDY; BLOOD CLOT LYSIS; CEREBROVASCULAR DISEASE; EMBOLIC STROKE;

AGED; BRAIN ISCHEMIA; FEMALE; HOSPITAL MORTALITY; HUMANS; MALE; MIDDLE AGED; RETROSPECTIVE STUDIES; SMOKING; STROKE;

CEREBROVASCULAR DISEASE; EMBOLIC STROKE; MORTALITY; THROMBOLYSIS;

EID: 85052549710     PISSN: None     EISSN: 20479980     Source Type: Journal    
DOI: 10.1161/JAHA.113.000161     Document Type: Article

References (30)

1. Helmers C. Short and long-term prognostic indices in acute myocardial infarction. A study of 606 patients initially treated in a coronary care unit. Acta Med Scand Suppl. 1973;555:7-26.
2. Kelly TL, Gilpin E, Ahnve S, Henning H, Ross J Jr. Smoking status at the time of acute myocardial infarction and subsequent prognosis. Am Heart J. 1985; 110:535-541.
3. Sparrow D, Dawber TR. The influence of cigarette smoking on prognosis after a first myocardial infarction. A report from the Framingham study. J Chronic Dis. 1978;31:425-432.
4. Weinblatt E, Shapiro S, Frank CW, Sager RV. Prognosis of men after first myocardial infarction: mortality and first recurrence in relation to selected parameters. Am J Public Health Nations Health. 1968;58:1329-1347.
5. Lavie CJ, Milani RV, Ventura HO. Obesity and cardiovascular disease: risk factor, paradox, and impact of weight loss. J Am Coll Cardiol. 2009;53:1925- 1932.
6. Kadakia MB, Fox CS, Scirica BM, Murphy SA, Bonaca MP, Morrow DA. Central obesity and cardiovascular outcomes in patients with acute coronary syndrome: observations from the MERLIN-TIMI 36 trial. Heart. 2011;97: 1782-1787.
7. Ovbiagele B, Bath PM, Cotton D, Vinisko R, Diener HC. Obesity and recurrent vascular risk after a recent ischemic stroke. Stroke. 2011; 42:3397-3402.
8. Lancefield T, Clark DJ, Andrianopoulos N, Brennan AL, Reid CM, Johns J, Freeman M, Charter K, Duffy SJ, Ajani AE, Proietto J, Farouque O. Is there an obesity paradox after percutaneous coronary intervention in the contemporary era? An analysis from a multicenter Australian registry. JACC Cardiovasc Interv. 2010;3:660-668.
9. Romero-Corral A, Montori VM, Somers VK, Korinek J, Thomas RJ, Allison TG, Mookadam F, Lopez-Jimenez F. Association of bodyweight with total mortality and with cardiovascular events in coronary artery disease: a systematic review of cohort studies. Lancet. 2006;368:666-678.
10. Barbash GI, White HD, Modan M, Diaz R, Hampton JR, Heikkila J, Kristinsson A, Moulopoulos S, Paolasso EA, Van der Werf T. Significance of smoking in patients receiving thrombolytic therapy for acute myocardial infarction. Experience gleaned from the international tissue plasminogen activator/streptokinase mortality trial. Circulation. 1993;87:53-58.
11. Gourlay SG, Rundle AC, Barron HV. Smoking and mortality following acute myocardial infarction: results from the national registry of myocardial infarction 2 (NRMI 2). Nicotine Tob Res. 2002;4:101-107.
12. Kang SH, Suh JW, Choi DJ, Chae IH, Cho GY, Youn TJ, Cho YS, Yoon CH, Oh IY, Cho MC, Kim YJ, Chae SC, Kim JH, Ahn YK, Jeong MH. Cigarette smoking is paradoxically associated with low mortality risk after acute myocardial infarction. Nicotine Tob Res. 2012;0:nts248v1-nts248.
13. Chen KY, Rha SW, Li YJ, Jin Z, Minami Y, Park JY, Poddar KL, Ramasamy S, Wang L, Li GP, Choi CU, Oh DJ, Jeong MH. 'Smoker's paradox' in young patients with acute myocardial infarction. Clin Exp Pharmacol Physiol. 2012; 39:630-635.
14. Aune E, Roislien J, Mathisen M, Thelle DS, Otterstad JE. The "smoker's paradox" in patients with acute coronary syndrome: a systematic review. BMC Med. 2011;9:97.
15. Gomez MA, Karagounis LA, Allen A, Anderson JL. Effect of cigarette smoking on coronary patency after thrombolytic therapy for myocardial infarction. TEAM-2 investigators. Second multicenter thrombolytic trials of eminase in acute myocardial infarction. Am J Cardiol. 1993;72:373-378.
16. Barbash GI, Reiner J, White HD, Wilcox RG, Armstrong PW, Sadowski Z, Morris D, Aylward P, Woodlief LH, Topol EJ. Evaluation of paradoxic beneficial effects of smoking in patients receiving thrombolytic therapy for acute myocardial infarction: mechanism of the "smoker's paradox" from the GUSTO-I trial, with angiographic insights. Global utilization of streptokinase and tissue-plasminogen activator for occluded coronary arteries. J Am Coll Cardiol. 1995;26: 1222-1229.
17. Lee KL, Woodlief LH, Topol EJ, Weaver WD, Betriu A, Col J, Simoons M, Aylward P, Van de Werf F, Califf RM. Predictors of 30-day mortality in the era of reperfusion for acute myocardial infarction. Results from an international trial of 41,021 patients. GUSTO-I investigators. Circulation. 1995;91:1659-1668.
18. de Chillou C, Riff P, Sadoul N, Ethevenot G, Feldmann L, Isaaz K, Simon JP, Boursier M, Khalife K, Thisse JY, Aliot E. Influence of cigarette smoking on rate of reopening of the infarct-related coronary artery after myocardial infarction: a multivariate analysis. J Am Coll Cardiol. 1996;27:1662-1668.
19. Addad F, Dridi Z, Jemmali M, Mzoughi K, Hassine M, Ghrissi I, Hamdi S, Mahjoub M, Betbout F, Ben Farhat M, Gamra H. "Smoker's paradox" and reperfusion's strategy in acute myocardial infarction. Ann Cardiol Angeiol (Paris). 2010;59:183-189.
20. Ovbiagele B, Saver JL. The smoking-thrombolysis paradox and acute ischemic stroke. Neurology. 2005;65:293-295.
21. Grines CL, Topol EJ, O'Neill WW, George BS, Kereiakes D, Phillips HR, Leimberger JD, Woodlief LH, Califf RM. Effect of cigarette smoking on outcome after thrombolytic therapy for myocardial infarction. Circulation. 1995; 91:298-303.
22. Gottlieb S, Boyko V, Zahger D, Balkin J, Hod H, Pelled B, Stern S, Behar S. Smoking and prognosis after acute myocardial infarction in the thrombolytic era (Israeli Thrombolytic National Survey). J Am Coll Cardiol. 1996;28:1506-1513.
23. Mueller HS, Cohen LS, Braunwald E, Forman S, Feit F, Ross A, Schweiger M, Cabin H, Davison R, Miller D, et al Predictors of early morbidity and mortality after thrombolytic therapy of acute myocardial infarction. Analyses of patient subgroups in the thrombolysis in myocardial infarction (TIMI) trial, phase II. Circulation. 1992;85:1254-1264.
24. Palnum KD, Petersen P, Sorensen HT, Ingeman A, Mainz J, Bartels P, Johnsen SP. Older patients with acute stroke in Denmark: quality of care and shortterm mortality. A nationwide follow-up study. Age Ageing. 2008;37:90-95.
25. Smith EE, Shobha N, Dai D, Olson DM, Reeves MJ, Saver JL, Hernandez AF, Peterson ED, Fonarow GC, Schwamm LH. Risk score for in-hospital ischemic stroke mortality derived and validated within the get with the guidelines-stroke program. Circulation. 2010;122:1496-1504.
26. van Domburg RT, Meeter K, van Berkel DF, Veldkamp RF, van Herwerden LA, Bogers AJ. Smoking cessation reduces mortality after coronary artery bypass surgery: a 20-year follow-up study. J Am Coll Cardiol. 2000;36:878-883.
27. Vlietstra RE, Kronmal RA, Frye RL, Seth AK, Tristani FE, Killip T III. Factors affecting the extent and severity of coronary artery disease in patients enrolled in the coronary artery surgery study. Arteriosclerosis. 1982;2:208-215.
28. Purcell IF, Newall N, Farrer M. Lower cardiac mortality in smokers following thrombolysis for acute myocardial infarction may be related to more effective fibrinolysis. QJM. 1999;92:327-333.
29. McGill HC Jr. The cardiovascular pathology of smoking. Am Heart J. 1988; 115:250-257.
30. Zidovetzki R, Chen P, Fisher M, Hofman FM, Faraci FM. Nicotine increases plasminogen activator inhibitor-1 production by human brain endothelial cells via protein kinase C-associated pathway. Stroke. 1999;30:651-655