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Volumn 61, Issue 10, 2018, Pages 2126-2133

SGLT inhibitor adjunct therapy in type 1 diabetes

Author keywords

Clinical trials; Diabetic ketoacidosis; GLP 1 receptor agonist; HbA1c; Hypoglycaemia; Insulin; Review; Sodium glucose cotransporter inhibitors; Type 1 diabetes; Weight

Indexed keywords

DAPAGLIFLOZIN; HEMOGLOBIN A1C; SODIUM GLUCOSE COTRANSPORTER INHIBITOR; SOTAGLIFLOZIN; (2S,3R,4R,5S,6R)-2-(4-CHLORO-3-(4-ETHOXYBENZYL)PHENYL)-6-(METHYLTHIO)TETRAHYDRO-2H-PYRAN-3,4,5-TRIOL; 2-(3-(4-ETHOXYBENZYL)-4-CHLOROPHENYL)-6-HYDROXYMETHYLTETRAHYDRO-2H-PYRAN-3,4,5-TRIOL; ANTIDIABETIC AGENT; BENZHYDRYL DERIVATIVE; GLUCOSIDE; GLYCOSIDE; SLC5A1 PROTEIN, HUMAN; SODIUM GLUCOSE COTRANSPORTER 1;

EID: 85052122808     PISSN: 0012186X     EISSN: 14320428     Source Type: Journal    
DOI: 10.1007/s00125-018-4671-6     Document Type: Review
Times cited : (67)

References (35)
  • 1
    • 0027370108 scopus 로고
    • The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus
    • Diabetes Control and Complications Trial Research Group, Nathan DM, Genuth S et al (1993) The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus. N Engl J Med 329:977–986
    • (1993) N Engl J Med , vol.329 , pp. 977-986
    • Nathan, D.M.1    Genuth, S.2
  • 2
    • 29144453326 scopus 로고    scopus 로고
    • Intensive diabetes treatment and cardiovascular disease in patients with type 1 diabetes
    • PID: 16371630
    • Nathan DM, Cleary PA, Backlund JY et al (2005) Intensive diabetes treatment and cardiovascular disease in patients with type 1 diabetes. N Engl J Med 353:2643–2653
    • (2005) N Engl J Med , vol.353 , pp. 2643-2653
    • Nathan, D.M.1    Cleary, P.A.2    Backlund, J.Y.3
  • 3
    • 84855299009 scopus 로고    scopus 로고
    • The physiology and pathophysiology of the neural control of the counterregulatory response
    • Beall C, Ashford ML, McCrimmon RJ (2012) The physiology and pathophysiology of the neural control of the counterregulatory response. Am J Phys Regul Integr Comp Phys 302:R215–R223
    • (2012) Am J Phys Regul Integr Comp Phys , vol.302 , pp. R215-R223
    • Beall, C.1    Ashford, M.L.2    McCrimmon, R.J.3
  • 4
    • 0031006603 scopus 로고    scopus 로고
    • Hypoglycemia in the Diabetes Control and Complications Trial
    • Diabetes Control and Complications Trial Research Group (1997) Hypoglycemia in the Diabetes Control and Complications Trial. Diabetes 46:271–286
    • (1997) Diabetes , vol.46 , pp. 271-286
  • 5
    • 0023791423 scopus 로고
    • Weight gain associated with intensive therapy in the diabetes control and complications trial
    • The DCCT Research Group (1988) Weight gain associated with intensive therapy in the diabetes control and complications trial. Diabetes Care 11:567–573
    • (1988) Diabetes Care , vol.11 , pp. 567-573
  • 6
    • 84948716018 scopus 로고    scopus 로고
    • Glycaemic control of type 1 diabetes in clinical practice early in the 21st century: an international comparison
    • PID: 25510978
    • McKnight JA, Wild SH, Lamb MJ et al (2015) Glycaemic control of type 1 diabetes in clinical practice early in the 21st century: an international comparison. Diabet Med 32:1036–1050
    • (2015) Diabet Med , vol.32 , pp. 1036-1050
    • McKnight, J.A.1    Wild, S.H.2    Lamb, M.J.3
  • 7
    • 84942755473 scopus 로고    scopus 로고
    • Current state of type 1 diabetes treatment in the U.S.: updated data from the T1D Exchange clinic registry
    • PID: 25998289
    • Miller KM, Foster NC, Beck RW et al (2015) Current state of type 1 diabetes treatment in the U.S.: updated data from the T1D Exchange clinic registry. Diabetes Care 38:971–978
    • (2015) Diabetes Care , vol.38 , pp. 971-978
    • Miller, K.M.1    Foster, N.C.2    Beck, R.W.3
  • 8
    • 84920509071 scopus 로고    scopus 로고
    • Estimated life expectancy in a Scottish cohort with type 1 diabetes, 2008-2010
    • PID: 25562264
    • Livingstone SJ, Levin D, Looker HC et al (2015) Estimated life expectancy in a Scottish cohort with type 1 diabetes, 2008-2010. JAMA 313:37–44
    • (2015) JAMA , vol.313 , pp. 37-44
    • Livingstone, S.J.1    Levin, D.2    Looker, H.C.3
  • 9
    • 84872714268 scopus 로고    scopus 로고
    • Potential role of non-insulin adjunct therapy in type 1 diabetes
    • PID: 22804102
    • George P, McCrimmon RJ (2013) Potential role of non-insulin adjunct therapy in type 1 diabetes. Diabet Med 30:179–188
    • (2013) Diabet Med , vol.30 , pp. 179-188
    • George, P.1    McCrimmon, R.J.2
  • 10
    • 33747763918 scopus 로고    scopus 로고
    • A double-blind, placebo-controlled trial assessing pramlintide treatment in the setting of intensive insulin therapy in type 1 diabetes
    • PID: 17003291
    • Edelman S, Garg S, Frias J et al (2006) A double-blind, placebo-controlled trial assessing pramlintide treatment in the setting of intensive insulin therapy in type 1 diabetes. Diabetes Care 29:2189–2195
    • (2006) Diabetes Care , vol.29 , pp. 2189-2195
    • Edelman, S.1    Garg, S.2    Frias, J.3
  • 11
    • 84908347082 scopus 로고    scopus 로고
    • Combination therapy with sitagliptin and lansoprazole in patients with recent-onset type 1 diabetes (REPAIR-T1D): 12-month results of a multicentre, randomised, placebo-controlled, phase 2 trial
    • PID: 24997559
    • Griffin KJ, Thompson PA, Gottschalk M, Kyllo JH, Rabinovitch A (2014) Combination therapy with sitagliptin and lansoprazole in patients with recent-onset type 1 diabetes (REPAIR-T1D): 12-month results of a multicentre, randomised, placebo-controlled, phase 2 trial. Lancet Diabetes Endocrinol 2:710–718
    • (2014) Lancet Diabetes Endocrinol , vol.2 , pp. 710-718
    • Griffin, K.J.1    Thompson, P.A.2    Gottschalk, M.3    Kyllo, J.H.4    Rabinovitch, A.5
  • 12
    • 84878349609 scopus 로고    scopus 로고
    • Addition of exenatide or sitagliptin to insulin in new onset type 1 diabetes: a randomized, open label study
    • PID: 23490599
    • Hari Kumar KV, Shaikh A, Prusty P (2013) Addition of exenatide or sitagliptin to insulin in new onset type 1 diabetes: a randomized, open label study. Diabetes Res Clin Pract 100:e55–e58
    • (2013) Diabetes Res Clin Pract , vol.100 , pp. e55-e58
    • Hari Kumar, K.V.1    Shaikh, A.2    Prusty, P.3
  • 13
    • 84899961714 scopus 로고    scopus 로고
    • Dipeptidyl peptidase 4 inhibitor sitagliptin maintains β-cell function in patients with recent-onset latent autoimmune diabetes in adults: one year prospective study
    • PID: 24432999
    • Zhao Y, Yang L, Xiang Y et al (2014) Dipeptidyl peptidase 4 inhibitor sitagliptin maintains β-cell function in patients with recent-onset latent autoimmune diabetes in adults: one year prospective study. J Clin Endocrinol Metab 99:E876–E880
    • (2014) J Clin Endocrinol Metab , vol.99 , pp. E876-E880
    • Zhao, Y.1    Yang, L.2    Xiang, Y.3
  • 14
    • 84988911581 scopus 로고    scopus 로고
    • Efficacy and safety of liraglutide added to insulin treatment in type 1 diabetes: the ADJUNCT ONE treat-to-target randomized trial
    • PID: 27506222
    • Mathieu C, Zinman B, Hemmingsson JU et al (2016) Efficacy and safety of liraglutide added to insulin treatment in type 1 diabetes: the ADJUNCT ONE treat-to-target randomized trial. Diabetes Care 39:1702–1710
    • (2016) Diabetes Care , vol.39 , pp. 1702-1710
    • Mathieu, C.1    Zinman, B.2    Hemmingsson, J.U.3
  • 15
    • 85020425866 scopus 로고    scopus 로고
    • Cardiovascular and metabolic effects of metformin in patients with type 1 diabetes (REMOVAL): a double-blind, randomised, placebo-controlled trial
    • PID: 28615149
    • Petrie JR, Chaturvedi N, Ford I et al (2017) Cardiovascular and metabolic effects of metformin in patients with type 1 diabetes (REMOVAL): a double-blind, randomised, placebo-controlled trial. Lancet Diabetes Endocrinol 5:597–609
    • (2017) Lancet Diabetes Endocrinol , vol.5 , pp. 597-609
    • Petrie, J.R.1    Chaturvedi, N.2    Ford, I.3
  • 17
    • 84864283226 scopus 로고    scopus 로고
    • SGLT2 inhibition in diabetes mellitus: rationale and clinical prospects
    • PID: 22310849
    • Ferrannini E, Solini A (2012) SGLT2 inhibition in diabetes mellitus: rationale and clinical prospects. Nat Rev Endocrinol 8:495–502
    • (2012) Nat Rev Endocrinol , vol.8 , pp. 495-502
    • Ferrannini, E.1    Solini, A.2
  • 18
    • 84861886161 scopus 로고    scopus 로고
    • Empagliflozin, a novel potent and selective SGLT-2 inhibitor, improves glycaemic control alone and in combination with insulin in streptozotocin-induced diabetic rats, a model of type 1 diabetes mellitus
    • PID: 22268612
    • Luippold G, Klein T, Mark M, Grempler R (2012) Empagliflozin, a novel potent and selective SGLT-2 inhibitor, improves glycaemic control alone and in combination with insulin in streptozotocin-induced diabetic rats, a model of type 1 diabetes mellitus. Diabetes Obes Metab 14:601–607
    • (2012) Diabetes Obes Metab , vol.14 , pp. 601-607
    • Luippold, G.1    Klein, T.2    Mark, M.3    Grempler, R.4
  • 20
    • 84899105421 scopus 로고    scopus 로고
    • Sodium-glucose cotransporter 2 inhibition and glycemic control in type 1 diabetes: results of an 8-week open-label proof-of-concept trial
    • PID: 24595630
    • Perkins BA, Cherney DZ, Partridge H et al (2014) Sodium-glucose cotransporter 2 inhibition and glycemic control in type 1 diabetes: results of an 8-week open-label proof-of-concept trial. Diabetes Care 37:1480–1483
    • (2014) Diabetes Care , vol.37 , pp. 1480-1483
    • Perkins, B.A.1    Cherney, D.Z.2    Partridge, H.3
  • 21
    • 84942258219 scopus 로고    scopus 로고
    • Empagliflozin as adjunct to insulin in patients with type 1 diabetes: a 4-week, randomized, placebo-controlled trial (EASE-1)
    • PID: 26080652
    • Pieber TR, Famulla S, Eilbracht J et al (2015) Empagliflozin as adjunct to insulin in patients with type 1 diabetes: a 4-week, randomized, placebo-controlled trial (EASE-1). Diabetes Obes Metab 17:928–935
    • (2015) Diabetes Obes Metab , vol.17 , pp. 928-935
    • Pieber, T.R.1    Famulla, S.2    Eilbracht, J.3
  • 22
    • 84934442921 scopus 로고    scopus 로고
    • Exploring the potential of the SGLT2 inhibitor dapagliflozin in type 1 diabetes: a randomized, double-blind, placebo-controlled pilot study
    • PID: 25271207
    • Henry RR, Rosenstock J, Edelman S et al (2015) Exploring the potential of the SGLT2 inhibitor dapagliflozin in type 1 diabetes: a randomized, double-blind, placebo-controlled pilot study. Diabetes Care 38:412–419
    • (2015) Diabetes Care , vol.38 , pp. 412-419
    • Henry, R.R.1    Rosenstock, J.2    Edelman, S.3
  • 23
    • 84962362243 scopus 로고    scopus 로고
    • Efficacy and safety of canagliflozin, a sodium-glucose cotransporter 2 inhibitor, as add-on to insulin in patients with type 1 diabetes
    • PID: 26486192
    • Henry RR, Thakkar P, Tong C, Polidori D, Alba M (2015) Efficacy and safety of canagliflozin, a sodium-glucose cotransporter 2 inhibitor, as add-on to insulin in patients with type 1 diabetes. Diabetes Care 38:2258–2265
    • (2015) Diabetes Care , vol.38 , pp. 2258-2265
    • Henry, R.R.1    Thakkar, P.2    Tong, C.3    Polidori, D.4    Alba, M.5
  • 24
    • 84939621365 scopus 로고    scopus 로고
    • Sotagliflozin, a dual SGLT1 and SGLT2 inhibitor, as adjunct therapy to insulin in type 1 diabetes
    • PID: 26049551
    • Sands AT, Zambrowicz BP, Rosenstock J et al (2015) Sotagliflozin, a dual SGLT1 and SGLT2 inhibitor, as adjunct therapy to insulin in type 1 diabetes. Diabetes Care 38:1181–1188
    • (2015) Diabetes Care , vol.38 , pp. 1181-1188
    • Sands, A.T.1    Zambrowicz, B.P.2    Rosenstock, J.3
  • 25
    • 85031780039 scopus 로고    scopus 로고
    • Effects of sotagliflozin added to insulin in patients with type 1 diabetes
    • PID: 28899222
    • Garg SK, Henry RR, Banks P et al (2017) Effects of sotagliflozin added to insulin in patients with type 1 diabetes. N Engl J Med 377:2337–2348
    • (2017) N Engl J Med , vol.377 , pp. 2337-2348
    • Garg, S.K.1    Henry, R.R.2    Banks, P.3
  • 26
    • 85032161540 scopus 로고    scopus 로고
    • Twenty-four week efficacy and safety of sotagliflozin, a dual SGLT1 and SGLT2 inhibitor, as adjunct therapy to insulin in type 1 diabetes (inTandem 1)
    • Abstract
    • Buse JB, Garg SK, Rosenstock J, Banks P, Sawhney S, Strumph P (2017) Twenty-four week efficacy and safety of sotagliflozin, a dual SGLT1 and SGLT2 inhibitor, as adjunct therapy to insulin in type 1 diabetes (inTandem 1). Diabetes 66(Suppl 1):A18 Abstract
    • (2017) Diabetes , vol.66 , pp. A18
    • Buse, J.B.1    Garg, S.K.2    Rosenstock, J.3    Banks, P.4    Sawhney, S.5    Strumph, P.6
  • 27
    • 85055728877 scopus 로고    scopus 로고
    • 24-week efficacy and safety of sotagliflozin, a dual SGLT1 and SGLT2 inhibitor, as adjunct therapy to insulin in type 1 diabetes (inTandem2)
    • 185 (Abstract
    • Danne T, Cariou B, Banks P, Sawhney S, Strumph P (2017) 24-week efficacy and safety of sotagliflozin, a dual SGLT1 and SGLT2 inhibitor, as adjunct therapy to insulin in type 1 diabetes (inTandem2). Diabetologia 60(Suppl 1):S87 185 (Abstract)
    • (2017) Diabetologia , vol.60 , pp. S87
    • Danne, T.1    Cariou, B.2    Banks, P.3    Sawhney, S.4    Strumph, P.5
  • 28
    • 85029446459 scopus 로고    scopus 로고
    • Efficacy and safety of dapagliflozin in patients with inadequately controlled type 1 diabetes (DEPICT-1): 24 week results from a multicentre, double-blind, phase 3, randomised controlled trial
    • PID: 28919061
    • Dandona P, Mathieu C, Phillip M et al (2017) Efficacy and safety of dapagliflozin in patients with inadequately controlled type 1 diabetes (DEPICT-1): 24 week results from a multicentre, double-blind, phase 3, randomised controlled trial. Lancet Diabetes Endocrinol 5:864–876
    • (2017) Lancet Diabetes Endocrinol , vol.5 , pp. 864-876
    • Dandona, P.1    Mathieu, C.2    Phillip, M.3
  • 29
    • 85044956761 scopus 로고    scopus 로고
    • Effects of sotagliflozin added to insulin in type 1 diabetes
    • PID: 29514037
    • Garg SK, Strumph P (2018) Effects of sotagliflozin added to insulin in type 1 diabetes. N Engl J Med 378:967–968
    • (2018) N Engl J Med , vol.378 , pp. 967-968
    • Garg, S.K.1    Strumph, P.2
  • 30
    • 85034081535 scopus 로고    scopus 로고
    • Altered patterns of early metabolic decompensation in type 1 diabetes during treatment with a SGLT2 inhibitor: an insulin pump suspension study
    • PID: 29068709
    • Patel NS, Van Name MA, Cengiz E et al (2017) Altered patterns of early metabolic decompensation in type 1 diabetes during treatment with a SGLT2 inhibitor: an insulin pump suspension study. Diabetes Technol Ther 19:618–622
    • (2017) Diabetes Technol Ther , vol.19 , pp. 618-622
    • Patel, N.S.1    Van Name, M.A.2    Cengiz, E.3
  • 31
    • 84866123698 scopus 로고    scopus 로고
    • 1c on admission to hospital for diabetic ketoacidosis in type 1 diabetes
    • PID: 22733482
    • 1c on admission to hospital for diabetic ketoacidosis in type 1 diabetes. Diabetologia 55:2356–2360
    • (2012) Diabetologia , vol.55 , pp. 2356-2360
    • Govan, L.1    Maietti, E.2    Torsney, B.3
  • 32
    • 84892959743 scopus 로고    scopus 로고
    • The effect of empagliflozin on arterial stiffness and heart rate variability in subjects with uncomplicated type 1 diabetes mellitus
    • PID: 24475922
    • Cherney DZ, Perkins BA, Soleymanlou N et al (2014) The effect of empagliflozin on arterial stiffness and heart rate variability in subjects with uncomplicated type 1 diabetes mellitus. Cardiovasc Diabetol 13:28
    • (2014) Cardiovasc Diabetol , vol.13 , pp. 28
    • Cherney, D.Z.1    Perkins, B.A.2    Soleymanlou, N.3
  • 33
    • 84868116559 scopus 로고    scopus 로고
    • Risk of cardiovascular disease and total mortality in adults with type 1 diabetes: Scottish registry linkage study
    • PID: 23055834
    • Livingstone SJ, Looker HC, Hothersall EJ et al (2012) Risk of cardiovascular disease and total mortality in adults with type 1 diabetes: Scottish registry linkage study. PLoS Med 9:e1001321
    • (2012) PLoS Med , vol.9
    • Livingstone, S.J.1    Looker, H.C.2    Hothersall, E.J.3
  • 34
    • 84994644951 scopus 로고    scopus 로고
    • The impact of SGLT2 inhibitors, compared with insulin, on diabetic bone disease in a mouse model of type 1 diabetes
    • PID: 27989651
    • Thrailkill KM, Nyman JS, Bunn RC et al (2017) The impact of SGLT2 inhibitors, compared with insulin, on diabetic bone disease in a mouse model of type 1 diabetes. Bone 94:141–151
    • (2017) Bone , vol.94 , pp. 141-151
    • Thrailkill, K.M.1    Nyman, J.S.2    Bunn, R.C.3
  • 35
    • 85023777061 scopus 로고    scopus 로고
    • Canagliflozin and cardiovascular and renal events in type 2 diabetes
    • PID: 28605608
    • Neal B, Perkovic V, Mahaffey KW et al (2017) Canagliflozin and cardiovascular and renal events in type 2 diabetes. N Engl J Med 377:644–657
    • (2017) N Engl J Med , vol.377 , pp. 644-657
    • Neal, B.1    Perkovic, V.2    Mahaffey, K.W.3


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