Pharmacology of drugs of abuse

Principles of Pharmacology: The Pathophysiologic Basis of Drug Therapy: Third Edition

Volumn , Issue , 2012, Pages 641-688

  Martin, Peter R ^a,b   Patel, Sachin ^b   Swift, Robert M ^c,d  

^a VANDERBILT UNIVERSITY   (United States)

^b VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c BROWN UNIVERSITY   (United States)

^d PROVIDENCE VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 85050914843     PISSN: None     EISSN: None     Source Type: Book    
DOI: None     Document Type: Chapter

References (9)

1. Camí- J, Farré M. Mechanisms of disease: drug addiction. N Engl J Med 2003;349:975-986. (Current understanding of neural mechanisms leading to addiction.)
2. Dani JA, Harris RA. Nicotine addiction and comorbidity with alcohol abuse and mental illness. Nat Neurosci 2005;8:1465-1470. (Examines the interface between the neuropharmacologic underpinnings of nicotine addiction and psychiatric disorders, especially alcoholism.)
3. Goldstein RZ, Craig AD, Bechara A, Garavan H, Childress AR, Paulus MP, Volkow ND. The neurocircuitry of impaired insight in drug addiction. Trends Cog Sci 2009;13:372-380. (Discusses current understanding of lack of insight and awareness in addiction.)
4. Kalivas PW, O'Brien C. Drug addiction as a pathology of staged neuroplasticity. Neuropsychopharmacol 2007;33:166-180. (Review that links learning mechanisms to reward through the glutamatergic system.)
5. Koob GF, Le Moal M. Neurobiological mechanisms for opponent motivational processes in addiction. Philos Trans R Soc B Biol Sci 2008;363: 3113-3123. (Reviews relationships between stress and reward pathways.)
6. McLellan AT, Lewis DC, O'Brien CP, Kleber HD. Drug dependence, a chronic medical illness: implications for treatment, insurance, and outcomes evaluation. JAMA 2000;284:1689-1695. (Seminal analysis of the status of drug use disorders in the health care system.)
7. Nestler EJ. Transcriptional mechanisms of addiction: role of delta-FosB. Philos Trans R Soc B Biol Sci 2008;363:3245-3255. (Reviews the role of gene regulation as a unitary neurobiological mechanism in reward and stress responses.)
8. Alcoholics Anonymous. www.aa.org. (Excellent information on Alcoholics Anonymous.)
9. Substance Abuse and Mental Health Services Administration. www.samhsa.gov. (Contains a wealth of information about prevention and treatment and cooccurring diagnoses; also access to listings of evidence-based treatment practices.)