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Volumn 70, Issue 8, 2018, Pages 1175-1181

Emerging Treatment Models in Rheumatology: Challenges for Osteoarthritis Trials

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; DISEASE EXACERBATION; GENERAL CONDITION DETERIORATION; HUMAN; JOINT CAVITY; NOCICEPTIVE PAIN; NUCLEAR MAGNETIC RESONANCE IMAGING; OSTEOARTHRITIS; OUTCOME ASSESSMENT; PHENOTYPE; PRIORITY JOURNAL; REPLACEMENT ARTHROPLASTY; SIGNAL DETECTION; WESTERN ONTARIO AND MCMASTER UNIVERSITIES OSTEOARTHRITIS INDEX; CLINICAL TRIAL (TOPIC); METHODOLOGY; RHEUMATOLOGY;

EID: 85050607140     PISSN: 23265191     EISSN: 23265205     Source Type: Journal    
DOI: 10.1002/art.40515     Document Type: Article
Times cited : (31)

References (46)
  • 1
    • 84994092049 scopus 로고    scopus 로고
    • Global, regional, and national incidence, prevalence, and years lived with disability for 310 diseases and injuries, 1990–2015: a systematic analysis for the Global Burden of Disease Study 2015
    • GBD 2015 Disease and Injury Incidence and Prevalence Collaborators. Global, regional, and national incidence, prevalence, and years lived with disability for 310 diseases and injuries, 1990–2015: a systematic analysis for the Global Burden of Disease Study 2015. Lancet 2016;388:1545–602
    • (2016) Lancet , vol.388 , pp. 1545-1602
  • 2
    • 34147150632 scopus 로고    scopus 로고
    • Projections of primary and revision hip and knee arthroplasty in the United States from 2005 to 2030
    • Kurtz S, Ong K, Lau E, Mowat F, Halpern M. Projections of primary and revision hip and knee arthroplasty in the United States from 2005 to 2030. J Bone Joint Surg Am 2007;89:780–5
    • (2007) J Bone Joint Surg Am , vol.89 , pp. 780-785
    • Kurtz, S.1    Ong, K.2    Lau, E.3    Mowat, F.4    Halpern, M.5
  • 3
    • 0024268463 scopus 로고
    • Validation study of WOMAC: a health status instrument for measuring clinically important patient relevant outcomes to antirheumatic drug therapy in patients with osteoarthritis of the hip or knee
    • Bellamy N, Buchanan WW, Goldsmith CH, Campbell J, Stitt LW. Validation study of WOMAC: a health status instrument for measuring clinically important patient relevant outcomes to antirheumatic drug therapy in patients with osteoarthritis of the hip or knee. J Rheumatol 1988;15:1833–40
    • (1988) J Rheumatol , vol.15 , pp. 1833-1840
    • Bellamy, N.1    Buchanan, W.W.2    Goldsmith, C.H.3    Campbell, J.4    Stitt, L.W.5
  • 4
    • 85050594001 scopus 로고    scopus 로고
    • Sensitivity to change of single versus composite measures of pain in knee osteoarthritis
    • In press
    • Parkes MJ, Callaghan MJ, Tive L, Lunt M, Felson DT. Sensitivity to change of single versus composite measures of pain in knee osteoarthritis. J Rheumatol 2018. In press
    • (2018) J Rheumatol
    • Parkes, M.J.1    Callaghan, M.J.2    Tive, L.3    Lunt, M.4    Felson, D.T.5
  • 5
    • 84983387193 scopus 로고    scopus 로고
    • Sensitivity to change of patient-preference measures for pain in patients with knee osteoarthritis: data from two trials
    • Parkes MJ, Callaghan MJ, O'Neill TW, Forsythe LM, Lunt M, Felson DT. Sensitivity to change of patient-preference measures for pain in patients with knee osteoarthritis: data from two trials. Arthritis Care Res (Hoboken) 2016;68:1224–31
    • (2016) Arthritis Care Res (Hoboken) , vol.68 , pp. 1224-1231
    • Parkes, M.J.1    Callaghan, M.J.2    O'Neill, T.W.3    Forsythe, L.M.4    Lunt, M.5    Felson, D.T.6
  • 7
    • 0022617224 scopus 로고
    • Predicting treatment response in depressed and non-depressed chronic pain patients
    • Dworkin RH, Richlin DM, Handlin DS, Brand L. Predicting treatment response in depressed and non-depressed chronic pain patients. Pain 1986;24:343–53
    • (1986) Pain , vol.24 , pp. 343-353
    • Dworkin, R.H.1    Richlin, D.M.2    Handlin, D.S.3    Brand, L.4
  • 8
    • 84991030495 scopus 로고    scopus 로고
    • Intra-articular onabotulinumtoxinA in osteoarthritis knee pain: effect on human mechanistic pain biomarkers and clinical pain
    • Arendt-Nielsen L, Jiang GL, DeGryse R, Turkel CC. Intra-articular onabotulinumtoxinA in osteoarthritis knee pain: effect on human mechanistic pain biomarkers and clinical pain. Scand J Rheumatol 2017;46:303–16
    • (2017) Scand J Rheumatol , vol.46 , pp. 303-316
    • Arendt-Nielsen, L.1    Jiang, G.L.2    DeGryse, R.3    Turkel, C.C.4
  • 9
    • 84861186602 scopus 로고    scopus 로고
    • Conditioned pain modulation predicts duloxetine efficacy in painful diabetic neuropathy
    • Yarnitsky D, Granot M, Nahman-Averbuch H, Khamaisi M, Granovsky Y. Conditioned pain modulation predicts duloxetine efficacy in painful diabetic neuropathy. Pain 2012;153:1193–8
    • (2012) Pain , vol.153 , pp. 1193-1198
    • Yarnitsky, D.1    Granot, M.2    Nahman-Averbuch, H.3    Khamaisi, M.4    Granovsky, Y.5
  • 10
    • 85050606782 scopus 로고    scopus 로고
    • Reducing heterogeneity in OA clinical trials: data from a phase 2 study of SM04690, a novel, intra-articular, Wnt pathway inhibitor in knee osteoarthritis [abstract]
    • Conaghan PG, DiFrancesco A, Swearingen CJ, Kennedy S, Simsek I, Tambiah J, et al. Reducing heterogeneity in OA clinical trials: data from a phase 2 study of SM04690, a novel, intra-articular, Wnt pathway inhibitor in knee osteoarthritis [abstract]. Arthritis Rheumatol 2017;69 Suppl 10. URL: http://acrabstracts.org/abstract/reducing-heterogeneity-in-oa-clinical-trials-data-from-a-phase-2-study-of-sm04690-a-novel-intra-articular-wnt-pathway-inhibitor-in-knee-osteoarthritis/
    • (2017) Arthritis Rheumatol , vol.69
    • Conaghan, P.G.1    DiFrancesco, A.2    Swearingen, C.J.3    Kennedy, S.4    Simsek, I.5    Tambiah, J.6
  • 13
    • 33750203697 scopus 로고    scopus 로고
    • Acetaminophen, like conventional NSAIDs, may reduce synovitis in osteoarthritic knees
    • Brandt KD, Mazzuca SA, Buckwalter KA. Acetaminophen, like conventional NSAIDs, may reduce synovitis in osteoarthritic knees. Rheumatology (Oxford) 2006;45:1389–94
    • (2006) Rheumatology (Oxford) , vol.45 , pp. 1389-1394
    • Brandt, K.D.1    Mazzuca, S.A.2    Buckwalter, K.A.3
  • 14
    • 0025835964 scopus 로고
    • Comparison of an antiinflammatory dose of ibuprofen, an analgesic dose of ibuprofen, and acetaminophen in the treatment of patients with osteoarthritis of the knee
    • Bradley JD, Brandt KD, Katz BP, Kalasinski LA, Ryan SI. Comparison of an antiinflammatory dose of ibuprofen, an analgesic dose of ibuprofen, and acetaminophen in the treatment of patients with osteoarthritis of the knee. N Engl J Med 1991;325:87–91
    • (1991) N Engl J Med , vol.325 , pp. 87-91
    • Bradley, J.D.1    Brandt, K.D.2    Katz, B.P.3    Kalasinski, L.A.4    Ryan, S.I.5
  • 15
    • 79960334683 scopus 로고    scopus 로고
    • NSAIDs vs acetaminophen in knee and hip osteoarthritis: a systematic review regarding heterogeneity influencing the outcomes
    • Verkleij SP, Luijsterburg PA, Bohnen AM, Koes BW, Bierma-Zeinstra SM. NSAIDs vs acetaminophen in knee and hip osteoarthritis: a systematic review regarding heterogeneity influencing the outcomes. Osteoarthritis Cartilage 2011;19:921–9
    • (2011) Osteoarthritis Cartilage , vol.19 , pp. 921-929
    • Verkleij, S.P.1    Luijsterburg, P.A.2    Bohnen, A.M.3    Koes, B.W.4    Bierma-Zeinstra, S.M.5
  • 17
    • 84922616655 scopus 로고    scopus 로고
    • A systematic review of the efficacy and general safety of antibodies to NGF in the treatment of OA of the hip or knee
    • Schnitzer TJ, Marks JA. A systematic review of the efficacy and general safety of antibodies to NGF in the treatment of OA of the hip or knee. Osteoarthritis Cartilage 2015;23 Suppl 1:S8–17
    • (2015) Osteoarthritis Cartilage , vol.23 , pp. S8-17
    • Schnitzer, T.J.1    Marks, J.A.2
  • 18
    • 85050598744 scopus 로고    scopus 로고
    • Osteoarthritis Research Society International. Osteoarthritis: a serious disease. URL: https://www.oarsi.org/sites/default/files/docs/2016/oarsi_white_paper_oa_serious_disease_121416_1.pdf
    • Osteoarthritis: a serious disease
  • 19
    • 84886791856 scopus 로고    scopus 로고
    • Motion for debate: osteoarthritis clinical trials have not identified efficacious therapies because traditional imaging outcome measures are inadequate
    • Guermazi A, Roemer FW, Felson DT, Brandt KD. Motion for debate: osteoarthritis clinical trials have not identified efficacious therapies because traditional imaging outcome measures are inadequate. Arthritis Rheum 2013;65:2748–58
    • (2013) Arthritis Rheum , vol.65 , pp. 2748-2758
    • Guermazi, A.1    Roemer, F.W.2    Felson, D.T.3    Brandt, K.D.4
  • 21
    • 33747013778 scopus 로고    scopus 로고
    • Change in joint space width: hyaline articular cartilage loss or alteration in meniscus?
    • Hunter DJ, Zhang YQ, Tu X, Lavalley M, Niu JB, Amin S, et al. Change in joint space width: hyaline articular cartilage loss or alteration in meniscus? Arthritis Rheum 2006;54:2488–95
    • (2006) Arthritis Rheum , vol.54 , pp. 2488-2495
    • Hunter, D.J.1    Zhang, Y.Q.2    Tu, X.3    Lavalley, M.4    Niu, J.B.5    Amin, S.6
  • 22
    • 84988980721 scopus 로고    scopus 로고
    • Correlations of medial joint space width on fixed-flexed standing computed tomography and radiographs with cartilage and meniscal morphology on magnetic resonance imaging
    • Segal NA, Frick E, Duryea J, Roemer F, Guermazi A, Nevitt MC, et al. Correlations of medial joint space width on fixed-flexed standing computed tomography and radiographs with cartilage and meniscal morphology on magnetic resonance imaging. Arthritis Care Res (Hoboken) 2016;68:1410–6
    • (2016) Arthritis Care Res (Hoboken) , vol.68 , pp. 1410-1416
    • Segal, N.A.1    Frick, E.2    Duryea, J.3    Roemer, F.4    Guermazi, A.5    Nevitt, M.C.6
  • 23
    • 33750961447 scopus 로고    scopus 로고
    • Risedronate decreases biochemical markers of cartilage degradation but does not decrease symptoms or slow radiographic progression in patients with medial compartment osteoarthritis of the knee: results of the two-year multinational knee osteoarthritis structural arthritis study
    • Bingham CO III, Buckland-Wright JC, Garnero P, Cohen SB, Dougados M, Adami S, et al. Risedronate decreases biochemical markers of cartilage degradation but does not decrease symptoms or slow radiographic progression in patients with medial compartment osteoarthritis of the knee: results of the two-year multinational knee osteoarthritis structural arthritis study. Arthritis Rheum 2006;54:3494–507
    • (2006) Arthritis Rheum , vol.54 , pp. 3494-3507
    • Bingham, C.O.1    Buckland-Wright, J.C.2    Garnero, P.3    Cohen, S.B.4    Dougados, M.5    Adami, S.6
  • 24
    • 84872080405 scopus 로고    scopus 로고
    • A 2-year randomised, double-blind, placebo-controlled, multicentre study of oral selective iNOS inhibitor, cindunistat (SD-6010), in patients with symptomatic osteoarthritis of the knee
    • Hellio Le Graverand MP, Clemmer RS, Redifer P, Brunell RM, Hayes CW, Brandt KD, et al. A 2-year randomised, double-blind, placebo-controlled, multicentre study of oral selective iNOS inhibitor, cindunistat (SD-6010), in patients with symptomatic osteoarthritis of the knee. Ann Rheum Dis 2013;72:187–95
    • (2013) Ann Rheum Dis , vol.72 , pp. 187-195
    • Hellio Le Graverand, M.P.1    Clemmer, R.S.2    Redifer, P.3    Brunell, R.M.4    Hayes, C.W.5    Brandt, K.D.6
  • 26
    • 78549293613 scopus 로고    scopus 로고
    • Relationship between radiographic changes and symptoms or physical examination findings in subjects with symptomatic medial knee osteoarthritis: a three-year prospective study
    • Fukui N, Yamane S, Ishida S, Tanaka K, Masuda R, Tanaka N, et al. Relationship between radiographic changes and symptoms or physical examination findings in subjects with symptomatic medial knee osteoarthritis: a three-year prospective study. BMC Musculoskelet Disord 2010;11:269
    • (2010) BMC Musculoskelet Disord , vol.11 , pp. 269
    • Fukui, N.1    Yamane, S.2    Ishida, S.3    Tanaka, K.4    Masuda, R.5    Tanaka, N.6
  • 27
    • 84882570443 scopus 로고    scopus 로고
    • Radiographic joint space width is correlated with 4-year clinical outcomes in patients with knee osteoarthritis: data from the Osteoarthritis Initiative
    • Oak SR, Ghodadra A, Winalski CS, Miniaci A, Jones MH. Radiographic joint space width is correlated with 4-year clinical outcomes in patients with knee osteoarthritis: data from the Osteoarthritis Initiative. Osteoarthritis Cartilage 2013;21:1185–90
    • (2013) Osteoarthritis Cartilage , vol.21 , pp. 1185-1190
    • Oak, S.R.1    Ghodadra, A.2    Winalski, C.S.3    Miniaci, A.4    Jones, M.H.5
  • 28
    • 33846215176 scopus 로고    scopus 로고
    • Is self-reported improvement in osteoarthritis pain and disability reflected in objective measures?
    • Johnson SR, Archibald A, Davis AM, Badley E, Wright JG, Hawker GA. Is self-reported improvement in osteoarthritis pain and disability reflected in objective measures? J Rheumatol 2007;34:159–64
    • (2007) J Rheumatol , vol.34 , pp. 159-164
    • Johnson, S.R.1    Archibald, A.2    Davis, A.M.3    Badley, E.4    Wright, J.G.5    Hawker, G.A.6
  • 29
    • 53049088235 scopus 로고    scopus 로고
    • Predicting the course of functional limitation among older adults with knee pain: do local signs, symptoms and radiographs add anything to general indicators?
    • Thomas E, Peat G, Mallen C, Wood L, Lacey R, Duncan R, et al. Predicting the course of functional limitation among older adults with knee pain: do local signs, symptoms and radiographs add anything to general indicators? Ann Rheum Dis 2008;67:1390–8
    • (2008) Ann Rheum Dis , vol.67 , pp. 1390-1398
    • Thomas, E.1    Peat, G.2    Mallen, C.3    Wood, L.4    Lacey, R.5    Duncan, R.6
  • 31
    • 84922648191 scopus 로고    scopus 로고
    • Serious joint-related adverse events in randomized controlled trials of anti-nerve growth factor monoclonal antibodies
    • Hochberg MC. Serious joint-related adverse events in randomized controlled trials of anti-nerve growth factor monoclonal antibodies. Osteoarthritis Cartilage 2015;23 Suppl 1:S18–21
    • (2015) Osteoarthritis Cartilage , vol.23 , pp. S18-21
    • Hochberg, M.C.1
  • 32
    • 0024413965 scopus 로고
    • Effect of non-steroidal anti-inflammatory drugs on the course of osteoarthritis
    • Rashad S, Revell P, Hemingway A, Low F, Rainsford K, Walker F. Effect of non-steroidal anti-inflammatory drugs on the course of osteoarthritis. Lancet 1989;2:519–22
    • (1989) Lancet , vol.2 , pp. 519-522
    • Rashad, S.1    Revell, P.2    Hemingway, A.3    Low, F.4    Rainsford, K.5    Walker, F.6
  • 33
    • 67449128722 scopus 로고    scopus 로고
    • Protective effects of licofelone, a 5-lipoxygenase and cyclo-oxygenase inhibitor, versus naproxen on cartilage loss in knee osteoarthritis: a first multicentre clinical trial using quantitative MRI
    • Raynauld JP, Martel-Pelletier J, Bias P, Laufer S, Haraoui B, Choquette D, et al. Protective effects of licofelone, a 5-lipoxygenase and cyclo-oxygenase inhibitor, versus naproxen on cartilage loss in knee osteoarthritis: a first multicentre clinical trial using quantitative MRI. Ann Rheum Dis 2009;68:938–47
    • (2009) Ann Rheum Dis , vol.68 , pp. 938-947
    • Raynauld, J.P.1    Martel-Pelletier, J.2    Bias, P.3    Laufer, S.4    Haraoui, B.5    Choquette, D.6
  • 34
    • 84903455882 scopus 로고    scopus 로고
    • Intraarticular sprifermin (recombinant human fibroblast growth factor 18) in knee osteoarthritis: a randomized, double-blind, placebo-controlled trial
    • Lohmander LS, Hellot S, Dreher D, Krantz EF, Kruger DS, Guermazi A, et al. Intraarticular sprifermin (recombinant human fibroblast growth factor 18) in knee osteoarthritis: a randomized, double-blind, placebo-controlled trial. Arthritis Rheumatol 2014;66:1820–31
    • (2014) Arthritis Rheumatol , vol.66 , pp. 1820-1831
    • Lohmander, L.S.1    Hellot, S.2    Dreher, D.3    Krantz, E.F.4    Kruger, D.S.5    Guermazi, A.6
  • 38
    • 79953674495 scopus 로고    scopus 로고
    • Fluctuation of knee pain and changes in bone marrow lesions, effusions, and synovitis on magnetic resonance imaging
    • Zhang Y, Nevitt M, Niu J, Lewis C, Torner J, Guermazi A, et al. Fluctuation of knee pain and changes in bone marrow lesions, effusions, and synovitis on magnetic resonance imaging. Arthritis Rheum 2011;63:691–9
    • (2011) Arthritis Rheum , vol.63 , pp. 691-699
    • Zhang, Y.1    Nevitt, M.2    Niu, J.3    Lewis, C.4    Torner, J.5    Guermazi, A.6
  • 39
  • 40
    • 84863825071 scopus 로고    scopus 로고
    • Zoledronic acid reduces knee pain and bone marrow lesions over 1 year: a randomised controlled trial
    • Laslett LL, Dore DA, Quinn SJ, Boon P, Ryan E, Winzenberg TM, et al. Zoledronic acid reduces knee pain and bone marrow lesions over 1 year: a randomised controlled trial. Ann Rheum Dis 2012;71:1322–8
    • (2012) Ann Rheum Dis , vol.71 , pp. 1322-1328
    • Laslett, L.L.1    Dore, D.A.2    Quinn, S.J.3    Boon, P.4    Ryan, E.5    Winzenberg, T.M.6
  • 41
    • 27744455752 scopus 로고    scopus 로고
    • Lessons learned from nine clinical trials of disease-modifying osteoarthritis drugs [review]
    • Brandt KD, Mazzuca SA. Lessons learned from nine clinical trials of disease-modifying osteoarthritis drugs [review]. Arthritis Rheum 2005;52:3349–59
    • (2005) Arthritis Rheum , vol.52 , pp. 3349-3359
    • Brandt, K.D.1    Mazzuca, S.A.2
  • 42
    • 62949246527 scopus 로고
    • Radiological assessment of osteo-arthrosis
    • Kellgren JH, Lawrence JS. Radiological assessment of osteo-arthrosis. Ann Rheum Dis 1957;16:494–502
    • (1957) Ann Rheum Dis , vol.16 , pp. 494-502
    • Kellgren, J.H.1    Lawrence, J.S.2
  • 43
    • 2342624080 scopus 로고    scopus 로고
    • EGFR mutations in lung cancer: correlation with clinical response to gefitinib therapy
    • Paez JG, Jänne PA, Lee JC, Tracy S, Greulich H, Gabriel S, et al. EGFR mutations in lung cancer: correlation with clinical response to gefitinib therapy. Science 2004;304:1497–1500
    • (2004) Science , vol.304 , pp. 1497-1500
    • Paez, J.G.1    Jänne, P.A.2    Lee, J.C.3    Tracy, S.4    Greulich, H.5    Gabriel, S.6
  • 45
    • 84978064544 scopus 로고    scopus 로고
    • Adaptive designs for clinical trials
    • Bhatt DL, Mehta C. Adaptive designs for clinical trials. N Engl J Med 2016;375:65–74
    • (2016) N Engl J Med , vol.375 , pp. 65-74
    • Bhatt, D.L.1    Mehta, C.2
  • 46
    • 85017466480 scopus 로고    scopus 로고
    • Cryoneurolysis to treat the pain and symptoms of knee osteoarthritis: a multicenter, randomized, double-blind, sham-controlled trial
    • Radnovich R, Scott D, Patel AT, Olson R, Dasa V, Segal N, et al. Cryoneurolysis to treat the pain and symptoms of knee osteoarthritis: a multicenter, randomized, double-blind, sham-controlled trial. Osteoarthritis Cartilage 2017;25:1247–56
    • (2017) Osteoarthritis Cartilage , vol.25 , pp. 1247-1256
    • Radnovich, R.1    Scott, D.2    Patel, A.T.3    Olson, R.4    Dasa, V.5    Segal, N.6


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