Thrombin generation potential and clot-forming capacity of thawed fresh-frozen plasma, plasma frozen within 24 h and solvent/detergent-treated plasma (octaplasLG®), during 5-day storage at 1–6°C

Vox Sanguinis

Volumn 113, Issue 5, 2018, Pages 485-488

  Heger, A ^a   Neisser Svae, A ^a   Trawnicek, L ^a   Triulzi, D ^b  

^a Octapharma Pharmazeutika Produktions GmbH   (Austria)

^b INSTITUTE FOR TRANSFUSION MEDICINE   (United States)

Author keywords

fresh frozen plasma; haemostatic potential; octaplas; stability; thawed plasma

Indexed keywords

DETERGENT; FRESH FROZEN PLASMA; POOLED PLASMA (HUMAN); SOLVENT; THROMBIN;

ARTICLE; BLOOD CLOTTING; BLOOD CLOTTING TIME; DRUG STABILITY; HEMOSTASIS; IN VITRO STUDY; PRIORITY JOURNAL; STORAGE TEMPERATURE; THROMBOELASTOGRAPHY;

EID: 85050276330     PISSN: 00429007     EISSN: 14230410     Source Type: Journal    
DOI: 10.1111/vox.12656     Document Type: Article

References (12)

1. FDA. Guidance for industry: an acceptable circular of information for the use of human blood and blood components. Silver Spring, MD: U.S. Food and Drug Administration, 2014
2. Circular of information for the use of human blood and blood components [Internet]. Bethesda, MD: AABB, 2014 [Last accessed October 2017]. Available from http://www.aabb.org/tm/coi/Documents/coi1017.pdf
3. Sheffield WP, Bhakta V, Yi QL, et al.: Stability of thawed apheresis fresh-frozen plasma stored for up to 120 hours at 1°C to 6°C. J Blood Transfusion 2016; 2016:Article ID 6260792, 7 pages
4. Sheffield WP, Bhakta V, Mastronardi C, et al.: Changes in coagulation factor activity and content of di(2-ethylethyl)phthalate in frozen plasma units during refrigerated storage for up to five days after thawing. Transfusion 2012; 52:493–502
5. Green L, Cardigan R, Beattie C, et al.: Addendum to the British Committee for Standards in Haematology (BCSH): Guidelines for the use of fresh-frozen plasma, cryoprecipitate and cryosupernatant, 2004 (Br J Haematol 2004, 126, 11-28). Br J Haematol 2016; 178:646–647
6. Council of Europe. Guide to the preparation, use and quality assurance of blood components. Recommendation No.R(95) 15, 19th Edn, 2017. Strasbourg: Council of Europe
7. Dargaud Y, Sorensen B, Shima M, et al.: Global haemostasis and point of care testing. Haemophilia 2012; 18:81–88
8. Neisser-Svae A, Trawnicek L, Heger A, et al.: Five-day stability of thawed plasma: solvent/detergent-treated plasma comparable with fresh-frozen plasma and plasma frozen within 24 hours. Transfusion 2016; 56:404–409
9. ®) with focus on protein S and its impact in different thrombin generation assay set-ups. Vox Sang 2016; 111:266–267
10. Matijevic N, Kostousov V, Wang Y-WW, et al.: Multiple levels of degradation diminish hemostatic potential of thawed plasma. J Trauma 2011; 70:71–80
11. Erickson A, Waldhaus K, David T, et al.: Plasma treated with amotosalen and ultraviolet A light retains activity for hemostasis after 5 days post-thaw storage at 1 to 6°C. Transfusion 2017; 57:997–1006
12. Cookson P, Lawrie A, Green L, et al.: Thrombin generation and coagulation factor content of thawed plasma and platelet concentrates. Vox Sang 2015; 108:160–168