Left-sided dominance of early-onset colorectal cancers: A rationale for screening flexible sigmoidoscopy in the young

Diseases of the Colon and Rectum

Volumn 61, Issue 8, 2018, Pages 897-902

  Segev, Lior ^a,b   Kalady, Matthew F ^a   Church, James M ^a  

^a LERNER RESEARCH INSTITUTE   (United States)

^b TEL AVIV UNIVERSITY   (Israel)

Author keywords

Colonoscopy; Colorectal cancer; Screening; Tumor location; Young patients

Indexed keywords

ADULT; ARTICLE; CANCER SCREENING; COLORECTAL CANCER; CONTROLLED STUDY; DESCENDING COLON; EARLY CANCER; FAMILY HISTORY; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; MIDDLE AGED; RECTUM; RETROSPECTIVE STUDY; SCREENING; SIGMOID; SIGMOIDOSCOPY; TRANSVERSE COLON; YOUNG ADULT; AGE; ANAMNESIS; CANCER STAGING; COLORECTAL TUMOR; DEMOGRAPHY; DIAGNOSTIC IMAGING; EARLY CANCER DIAGNOSIS; INCIDENCE; OUTCOME ASSESSMENT; PATHOLOGY; PROCEDURES; REPRODUCIBILITY; STATISTICS AND NUMERICAL DATA; UNITED STATES;

ADULT; AGE FACTORS; COLON, DESCENDING; COLON, SIGMOID; COLORECTAL NEOPLASMS; DEMOGRAPHY; EARLY DETECTION OF CANCER; FEMALE; HUMANS; INCIDENCE; MALE; MEDICAL HISTORY TAKING; MIDDLE AGED; NEOPLASM STAGING; OUTCOME ASSESSMENT (HEALTH CARE); RECTUM; REPRODUCIBILITY OF RESULTS; SIGMOIDOSCOPY; UNITED STATES;

EID: 85049974656     PISSN: 00123706     EISSN: 15300358     Source Type: Journal    
DOI: 10.1097/DCR.0000000000001062     Document Type: Article

References (27)

1. Siegel R, Desantis C, Jemal A. Colorectal cancer statistics, 2014. CA Cancer J Clin. 2014;64:104–117.
2. Siegel RL, Jemal A, Ward EM. Increase in incidence of colorectal cancer among young men and women in the United States. Cancer Epidemiol Biomarkers Prev. 2009;18:1695–1698.
3. Ahnen DJ, Wade SW, Jones WF, et al. The increasing incidence of young-onset colorectal cancer: a call to action. Mayo Clin Proc. 2014;89:216–224.
4. National Cancer Institute. Surveillance, Epidemiology, and End Results Program. Available at: https://seer.cancer.gov/faststats/selections.php?run=runit&output=1&data=1&statistic=1&ca ncer=20&year=201601&race=1&sex=1&subSite=20&series=a ge&age=75. Accessed on March 21, 2017.
5. You YN, Xing Y, Feig BW, Chang GJ, Cormier JN. Young-onset colorectal cancer: is it time to pay attention? Arch Intern Med. 2012;172:287–289.
6. US Preventive Services Task Force. Guide to Clinical Preventive Services: Report of the US Preventive Services Task Force; 2nd ed. Washington, DC: Department of Health and Human Services; 1995.
7. Nagai Y, Hata K, Kawai K, et al. Clinicopathological features of colorectal cancer patients under the age of 50: recent experience and case-control study of prognosis in a Japanese cohort. Digestion. 2016;93:272–279.
8. Sia CS, Paul E, Wale RJ, Lynch AC, Heriot AG, Warrier SK. No increase in colorectal cancer in patients under 50 years of age: a Victorian experience from the last decade. Colorectal Dis. 2014;16:690–695.
9. Myers EA, Feingold DL, Forde KA, Arnell T, Jang JH, Whelan RL. Colorectal cancer in patients under 50 years of age: a retrospective analysis of two institutions’ experience. World J Gastroenterol. 2013;19:5651–5657.
10. Jones HG, Radwan R, Davies M, et al. Clinicopathological characteristics of colorectal cancer presenting under the age of 50. Int J Colorectal Dis. 2015;30:483–489.
11. Schellerer VS, Merkel S, Schumann SC, et al. Despite aggressive histopathology survival is not impaired in young patients with colorectal cancer: CRC in patients under 50 years of age. Int J Colorectal Dis. 2012;27:71–79.
12. Xu Y, Hu B, Choi AJ, et al. Unique DNA methylome profiles in CpG island methylator phenotype colon cancers. Genome Res. 2012;22:283–291.
13. Sanchez JA, Krumroy L, Plummer S, et al. Genetic and epigenetic classifications define clinical phenotypes and determine patient outcomes in colorectal cancer. Br J Surg. 2009;96:1196–1204.
14. Edge S, Byrd D, Compton C, Fritz A, Frederick G, Trotti A, eds. AJCC Cancer Staging Manual. 7th ed. New York: Springer; 2009.
15. O’Connell JB, Maggard MA, Livingston EH, Yo CK. Colorectal cancer in the young. Am J Surg. 2004;187:343–348.
16. Griffin PM, Liff JM, Greenberg RS, Clark WS. Adenocarcino-mas of the colon and rectum in persons under 40 years old. A population-based study. Gastroenterology. 1991;100:1033–1040.
17. Rex DK, Johnson DA, Anderson JC, Schoenfeld PS, Burke CA, Inadomi JM; American College of Gastroenterology. American College of Gastroenterology guidelines for colorectal cancer screening 2009 [corrected]. Am J Gastroenterol. 2009;104:739–750.
18. Rex DK, Boland CR, Dominitz JA, et al. Colorectal cancer screening: recommendations for physicians and patients from the U.S. Multi-Society Task Force on Colorectal Cancer. Gastroenterology. 2017;153:307–323.
19. Bibbins-Domingo K, Grossman DC, Curry SJ et al; US Preventive Services Task Force. Screening for Colorectal Cancer: US Preventive Services Task Force Recommendation Statement. JAMA. 2016;315: 2564–2575.
20. Liang J, Kalady MF, Church J. Young age of onset colorectal cancers. Int J Colorectal Dis. 2015;30:1653–1657.
21. Imperiale TF, Ransohoff DF, Itzkowitz SH, et al. Multitarget stool DNA testing for colorectal-cancer screening. N Engl J Med. 2014;370:1287–1297.
22. Cox B. Flexible sigmoidoscopy is the best approach for a national bowel screening programme. N Z Med J. 2016;129:14–17.
23. Church J. Colon cancer screening: the devil is in the details. N Z Med J. 2016;129:98–100.
24. Holme Ø, Løberg M, Kalager M, et al. Effect of flexible sigmoidoscopy screening on colorectal cancer incidence and mortality: a randomized clinical trial. JAMA. 2014;312:606–615.
25. Schoen RE, Pinsky PF, Weissfeld JL, et al; PLCO Project Team. Colorectal-cancer incidence and mortality with screening flexible sigmoidoscopy. N Engl J Med. 2012;366:2345–2357.
26. Baxter NN, Goldwasser MA, Paszat LF, Saskin R, Urbach DR, Rabeneck L. Association of colonoscopy and death from colorectal cancer. Ann Intern Med. 2009;150:1–8.
27. Lin JS, Piper MA, Perdue LA, et al. Screening for Colorectal Cancer: A Systematic Review for the U.S. Preventive Services Task Force. Rockville, MD: Agency for Healthcare Research and Quality (US); 2016. Report No.: 14-05203-EF-1.