Acute Kidney Injury in Sugarcane Workers at Risk for Mesoamerican Nephropathy

American Journal of Kidney Diseases

Volumn 72, Issue 4, 2018, Pages 475-482

  Kupferman, Joseph ^a   Ramírez Rubio, Oriana ^b   Amador, Juan José ^b   López Pilarte, Damaris ^b   Wilker, Elissa H ^a,c   Laws, Rebecca L ^b   Sennett, Caryn ^b   Robles, Ninoska Violeta ^d   Lau, Jorge Luis ^e   Salinas, Alejandro José ^e   Kaufman, James S ^f   Weiner, Daniel E ^g   Scammell, Madeleine K ^b   McClean, Michael D ^b   Brooks, Daniel R ^b   Friedman, David J ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

^b BOSTON UNIVERSITY SCHOOL OF PUBLIC HEALTH   (United States)

^c HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

^d Nicaraguan Ministry of Health   (Nicaragua)

^e Especialistas en Medicina Interna   (Nicaragua)

^f NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

^g TUFTS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Acute kidney injury (AKI); chistata; chronic kidney disease (CKD); CKD of non traditional etiology (CKDnt); CKD of unknown etiology (CKDu); heat stress; kidney function; Mesoamerican nephropathy (MeN); Nicaragua; occupational risk factor; serum creatinine; sugarcane worker

Indexed keywords

CREATININE;

ACUTE KIDNEY FAILURE; ADULT; AGRICULTURAL WORKER; ARTICLE; CONTROLLED STUDY; CREATININE BLOOD LEVEL; CROSS-SECTIONAL STUDY; ESTIMATED GLOMERULAR FILTRATION RATE; FOLLOW UP; HIGH RISK PATIENT; HUMAN; KIDNEY DISEASE; KIDNEY FUNCTION; MAJOR CLINICAL STUDY; MALE; MESOAMERICAN NEPHROPATHY; NICARAGUA; OCCUPATIONAL EXPOSURE; OCCUPATIONAL HAZARD; OUTCOME ASSESSMENT; RISK ASSESSMENT; SUGARCANE WORKER; BLOOD; CENTRAL AMERICA; CHEMICALLY INDUCED; CHRONIC KIDNEY FAILURE; DISEASE EXACERBATION; FACTUAL DATABASE; FEMALE; GLOMERULUS FILTRATION RATE; MIDDLE AGED; OCCUPATIONAL DISEASE; OCCUPATIONAL HEALTH; PATHOPHYSIOLOGY; PHYSIOLOGY; PREVALENCE; RETROSPECTIVE STUDY; STATISTICAL MODEL; STATISTICS AND NUMERICAL DATA; SUGARCANE;

ACUTE KIDNEY INJURY; ADULT; CENTRAL AMERICA; CREATININE; CROSS-SECTIONAL STUDIES; DATABASES, FACTUAL; DISEASE PROGRESSION; FARMERS; FEMALE; GLOMERULAR FILTRATION RATE; HUMANS; LINEAR MODELS; MALE; MIDDLE AGED; OCCUPATIONAL DISEASES; OCCUPATIONAL HEALTH; PREVALENCE; RENAL INSUFFICIENCY, CHRONIC; RETROSPECTIVE STUDIES; RISK ASSESSMENT; SACCHARUM;

EID: 85049348024     PISSN: 02726386     EISSN: 15236838     Source Type: Journal    
DOI: 10.1053/j.ajkd.2018.04.014     Document Type: Article

References (48)

1. Cohen, J., Mesoamerica's mystery killer. Science 344:6180 (2014), 143–147.
2. Chatterjee, R., Occupational hazard. Science 352:6281 (2016), 24–27.
3. Correa-Rotter, R., Wesseling, C., Johnson, R.J., CKD of unknown origin in Central America: the case for a Mesoamerican nephropathy. Am J Kidney Dis 63:3 (2014), 506–520.
4. Ordunez, P., Martinez, R., Reveiz, L., et al. Chronic kidney disease epidemic in Central America: urgent public health action is needed amid causal uncertainty. PLoS Negl Trop Dis, 8(8), 2014, e3019.
5. Garcia-Trabanino, R., Hernandez, C., Rosa, A., Dominguez Alonso, J., en nombre del Fondo Social de Emergencia para la Salud del canton Tierra Blanca ddUES. Incidence, mortality, and prevalence of end-stage chronic renal disease in the Bajo Lempa region of El Salvador: a ten-year community registry. Nefrologia 36:5 (2016), 517–522.
6. Weiner, D.E., McClean, M.D., Kaufman, J.S., Brooks, D.R., The Central American epidemic of CKD. Clin J Am Soc Nephrol 8:3 (2013), 504–511.
7. Johnson, R.J., Sanchez-Lozada, L.G., Chronic kidney disease: Mesoamerican nephropathy–new clues to the cause. Nat Rev Nephrol 9:10 (2013), 560–561.
8. Ordunez, P., Saenz, C., Martinez, R., Chapman, E., Reveiz, L., Becerra, F., The epidemic of chronic kidney disease in Central America. Lancet Global Health 2:8 (2014), e440–e441.
9. Campese, V.M., Con: Mesoamerican nephropathy: is the problem dehydration or rehydration?. Nephrol Dial Transplant 32:4 (2017), 603–606.
10. Johnson, R.J., Pro: Heat stress as a potential etiology of Mesoamerican and Sri Lankan nephropathy: a late night consult with Sherlock Holmes. Nephrol Dial Transplant 32:4 (2017), 598–602.
11. Glaser, J., Lemery, J., Rajagopalan, B., et al. Climate change and the emergent epidemic of CKD from heat stress in rural communities: the case for heat stress nephropathy. Clin J Am Soc Nephrol 11:8 (2016), 1472–1483.
12. Garcia-Trabanino, R., Jarquin, E., Wesseling, C., et al. Heat stress, dehydration, and kidney function in sugarcane cutters in El Salvador–a cross-shift study of workers at risk of Mesoamerican nephropathy. Environ Res 142 (2015), 746–755.
13. Johnson, R.J., Stenvinkel, P., Jensen, T., et al. Metabolic and kidney diseases in the setting of climate change, water shortage, and survival factors. J Am Soc Nephrol 27:8 (2016), 2247–2256.
14. Roncal Jimenez, C.A., Ishimoto, T., Lanaspa, M.A., et al. Fructokinase activity mediates dehydration-induced renal injury. Kidney Int 86:2 (2014), 294–302.
15. Roncal-Jimenez, C., Garcia-Trabanino, R., Barregard, L., et al. Heat stress nephropathy from exercise-induced uric acid crystalluria: a perspective on Mesoamerican nephropathy. Am J Kidney Dis 67:1 (2016), 20–30.
16. Torres, C., Aragon, A., Gonzalez, M., et al. Decreased kidney function of unknown cause in Nicaragua: a community-based survey. Am J Kidney Dis 55:3 (2010), 485–496.
17. McClean M, Amador JJ, Laws R, et al. Biological sampling report: investigating biomarkers of kidney injury and chronic kidney disease among workers in Western Nicaragua. 2012. http://www.cao-ombudsman.org/cases/document-links/documents/Biological_Sampling_Report_April_2012.pdf. Accessed April 25, 2018.
18. Raines, N., Gonzalez, M., Wyatt, C., et al. Risk factors for reduced glomerular filtration rate in a Nicaraguan community affected by Mesoamerican nephropathy. MEDICC Rev 16:2 (2014), 16–22.
19. Peraza, S., Wesseling, C., Aragon, A., et al. Decreased kidney function among agricultural workers in El Salvador. Am J Kidney Dis 59:4 (2012), 531–540.
20. Orantes, C.M., Herrera, R., Almaguer, M., et al. Epidemiology of chronic kidney disease in adults of Salvadoran agricultural communities. MEDICC Rev 16:2 (2014), 23–30.
21. Wesseling, C., Aragon, A., Gonzalez, M., et al. Heat stress, hydration and uric acid: a cross-sectional study in workers of three occupations in a hotspot of Mesoamerican nephropathy in Nicaragua. BMJ Open, 6(12), 2016, e011034.
22. Paula Santos, U., Zanetta, D.M., Terra-Filho, M., Burdmann, E.A., Burnt sugarcane harvesting is associated with acute renal dysfunction. Kidney Int 87:4 (2015), 792–799.
23. Wesseling, C., Aragon, A., Gonzalez, M., et al. Kidney function in sugarcane cutters in Nicaragua–a longitudinal study of workers at risk of Mesoamerican nephropathy. Environ Res 147 (2016), 125–132.
24. Madero, M., Garcia-Arroyo, F.E., Sanchez-Lozada, L.G., Pathophysiologic insight into MesoAmerican nephropathy. Curr Opin Nephrol Hypertens 26:4 (2017), 296–302.
25. Laws, R.L., Brooks, D.R., Amador, J.J., et al. Changes in kidney function among Nicaraguan sugarcane workers. Int J Occup Environ Health 21:3 (2015), 241–250.
26. Laws, R.L., Brooks, D.R., Amador, J.J., et al. Biomarkers of kidney injury among Nicaraguan sugarcane workers. Am J Kidney Dis 67:2 (2016), 209–217.
27. Elinder, C.G., Wernerson, A., Wijkström, J., Mesoamerican nephropathy (MeN): a ‘new’ chronic kidney disease related to occupational heat exposure with repeated deprivation of salts and water. Int J Nephrol Kidney Fail 1:2 (2015), 1–9.
28. Fischer, R.S.B., Mandayam, S., Chavarria, D., et al. Clinical evidence of acute Mesoamerican nephropathy. Am J Trop Med Hyg 97:4 (2017), 1247–1256.
29. Herath, C., Jayasumana, C., De Silva, P.M.C.S., De Silva, P.H.C., Siribaddana, S., De Broe, M.E., Kidney diseases in agricultural communities: a case against heat-stress nephropathy. Kidney Int Reports 3 (2018), 271–280.
30. Kupferman, J., Amador, J.J., Lynch, K.E., et al. Characterization of Mesoamerican nephropathy in a kidney failure hotspot in Nicaragua. Am J Kidney Dis 68:5 (2016), 716–725.
31. Weather Underground. Weather History for MNCH - March, 2015. https://www.wunderground.com/history/airport/MNCH/2015/3/1/MonthlyHistory.html?req_city=Chichigalpa&req_state=&req_statename=Nicaragua&reqdb.zip=00000&reqdb.magic=1&reqdb.wmo=78736&MR=1. Accessed May 1, 2017.
32. Roncal-Jimenez, C.A., Milagres, T., Andres-Hernando, A., et al. Effects of exogenous desmopressin on a model of heat stress nephropathy in mice. Am J Physiol Renal Physiol 312:3 (2017), F418–F426.
33. Grams, M.E., Sang, Y., Coresh, J., et al. Candidate surrogate end points for ESRD after AKI. J Am Soc Nephrol 27:9 (2016), 2851–2859.
34. Wijkstrom, J., Gonzalez-Quiroz, M., Hernandez, M., et al. Renal morphology, clinical findings, and progression rate in Mesoamerican nephropathy. Am J Kidney Dis 69:5 (2017), 626–636.
35. Wijkstrom, J., Leiva, R., Elinder, C.G., et al. Clinical and pathological characterization of Mesoamerican nephropathy: a new kidney disease in Central America. Am J Kidney Dis 62:5 (2013), 908–918.
36. Herrera, R., Orantes, C.M., Almaguer, M., et al. Clinical characteristics of chronic kidney disease of nontraditional causes in Salvadoran farming communities. MEDICC Rev 16:2 (2014), 39–48.
37. Lopez-Marin, L., Chavez, Y., Garcia, X.A., et al. Histopathology of chronic kidney disease of unknown etiology in Salvadoran agricultural communities. MEDICC Rev 16:2 (2014), 49–54.
38. Ramirez-Rubio, O., Brooks, D.R., Amador, J.J., Kaufman, J.S., Weiner, D.E., Scammell, M.K., Chronic kidney disease in Nicaragua: a qualitative analysis of semi-structured interviews with physicians and pharmacists. BMC Public Health, 13, 2013, 350.
39. McCambridge, J., Witton, J., Elbourne, D.R., Systematic review of the Hawthorne effect: new concepts are needed to study research participation effects. J Clin Epidemiol 67:3 (2014), 267–277.
40. Parr, S.K., Siew, E.D., Delayed consequences of acute kidney injury. Adv Chronic Kidney Dis 23:3 (2016), 186–194.
41. Thakar, C.V., Christianson, A., Himmelfarb, J., Leonard, A.C., Acute kidney injury episodes and chronic kidney disease risk in diabetes mellitus. Clin J Am Soc Nephrol 6:11 (2011), 2567–2572.
42. Chawla, L.S., Amdur, R.L., Amodeo, S., Kimmel, P.L., Palant, C.E., The severity of acute kidney injury predicts progression to chronic kidney disease. Kidney Int 79:12 (2011), 1361–1369.
43. Ishani, A., Xue, J.L., Himmelfarb, J., et al. Acute kidney injury increases risk of ESRD among elderly. J Am Soc Nephrol 20:1 (2009), 223–228.
44. Bucaloiu, I.D., Kirchner, H.L., Norfolk, E.R., Hartle, J.E. 2nd, Perkins, R.M., Increased risk of death and de novo chronic kidney disease following reversible acute kidney injury. Kidney Int 81:5 (2012), 477–485.
45. Heung, M., Steffick, D.E., Zivin, K., et al. Acute kidney injury recovery pattern and subsequent risk of CKD: an analysis of Veterans Health Administration data. Am J Kidney Dis 67:5 (2016), 742–752.
46. Sawhney, S., Marks, A., Fluck, N., et al. Post-discharge kidney function is associated with subsequent ten-year renal progression risk among survivors of acute kidney injury. Kidney Int 92:2 (2017), 440–452.
47. Basile, D.P., Bonventre, J.V., Mehta, R., et al. Progression after AKI: understanding maladaptive repair processes to predict and identify therapeutic treatments. J Am Soc Nephrol 27:3 (2016), 687–697.
48. Chawla, L.S., Eggers, P.W., Star, R.A., Kimmel, P.L., Acute kidney injury and chronic kidney disease as interconnected syndromes. N Engl J Med 371:1 (2014), 58–66.