Procalcitonin-guided antibiotic therapy in patients with fever in a general emergency department population: a multicentre non-inferiority randomized clinical trial (HiTEMP study)

Clinical Microbiology and Infection

Volumn 24, Issue 12, 2018, Pages 1282-1289

  van der Does, Y ^a   Limper, M ^b   Jie, K E ^c   Schuit, S C E ^a   Jansen, H ^c   Pernot, N ^c   van Rosmalen, J ^a   Poley, M J ^d,e   Ramakers, C ^a   Patka, P ^a   van Gorp, E C M ^a   Rood, P P M ^a  

^a ERASMUS MEDICAL CENTER   (Netherlands)

^b UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^c JEROEN BOSCH HOSPITAL   (Netherlands)

^d ERASMUS UNIVERSITY ROTTERDAM   (Netherlands)

^e SOPHIA CHILDREN S HOSPITAL   (Netherlands)

Author keywords

Antibiotics; Biomarkers; Emergency department; Fever; Procalcitonin

Indexed keywords

ANTIBIOTIC AGENT; C REACTIVE PROTEIN; PROCALCITONIN; ANTIINFECTIVE AGENT; BIOLOGICAL MARKER;

ADULT; AGED; ANTIBIOTIC THERAPY; AREA UNDER THE CURVE; ARTICLE; BACTEREMIA; BACTERIAL INFECTION; CLINICAL OUTCOME; CONTROLLED STUDY; COST MINIMIZATION ANALYSIS; DIAGNOSTIC ACCURACY; DIAGNOSTIC TEST ACCURACY STUDY; DRUG EFFICACY; EMERGENCY HEALTH SERVICE; FEMALE; FEVER; HOSPITAL ADMISSION; HUMAN; MAJOR CLINICAL STUDY; MALE; MULTICENTER STUDY; MYCOSIS; PARASITOSIS; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SENSITIVITY AND SPECIFICITY; VIRUS INFECTION; CLINICAL TRIAL; EQUIVALENCE TRIAL (TOPIC); HOSPITAL EMERGENCY SERVICE; INTENSIVE CARE UNIT; MICROBIOLOGY; MIDDLE AGED; NETHERLANDS; RESPIRATORY TRACT INFECTION; STATISTICS AND NUMERICAL DATA;

ADULT; AGED; ANTI-BACTERIAL AGENTS; BACTERIAL INFECTIONS; BIOMARKERS; EMERGENCY SERVICE, HOSPITAL; EQUIVALENCE TRIALS AS TOPIC; FEMALE; FEVER; HUMANS; INTENSIVE CARE UNITS; MALE; MIDDLE AGED; NETHERLANDS; PROCALCITONIN; RESPIRATORY TRACT INFECTIONS;

EID: 85049331105     PISSN: 1198743X     EISSN: 14690691     Source Type: Journal    
DOI: 10.1016/j.cmi.2018.05.011     Document Type: Article

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