Maternal and infant outcomes associated with lithium use in pregnancy: an international collaborative meta-analysis of six cohort studies

The Lancet Psychiatry

Volumn 5, Issue 8, 2018, Pages 644-652

  Munk Olsen, Trine ^a,b   Liu, Xiaoqin ^a   Viktorin, Alexander ^c   Brown, Hilary K ^d,e,f   Di Florio, Arianna ^g,h   D'Onofrio, Brian M ^c,i   Gomes, Tara ^d,f   Howard, Louise M ^j   Khalifeh, Hind ^j   Krohn, Holly ^h   Larsson, Henrik ^c   Lichtenstein, Paul ^c   Taylor, Clare L ^j   Van Kamp, Inge ^k   Wesseloo, Richard ^l   Meltzer Brody, Samantha ^h   Vigod, Simone N ^d,e,f   Bergink, Veerle ^l,m  

^a AARHUS UNIVERSITY   (Denmark)

^b Lundbeck Foundation Initiative for Integrative Psychiatric Research   (Denmark)

^c KAROLINSKA INSTITUTE   (Sweden)

^d UNIVERSITY OF TORONTO   (Canada)

^e WOMEN S COLLEGE HOSPITAL   (Canada)

^f INSTITUTE FOR CLINICAL EVALUATIVE SCIENCES   (Canada)

^g CARDIFF UNIVERSITY   (United Kingdom)

^h UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

ⁱ INDIANA UNIVERSITY   (United States)

^j KING'S COLLEGE LONDON   (United Kingdom)

^k LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^l ERASMUS MEDICAL CENTER   (Netherlands)

^m MOUNT SINAI SCHOOL OF MEDICINE   (United States)

more..

Author keywords

[No Author keywords available]

Indexed keywords

LITHIUM;

ADULT; ADVERSE OUTCOME; ARTICLE; BIPOLAR DEPRESSION; BIPOLAR DISORDER; CANADA; CESAREAN SECTION; CLINICAL PROTOCOL; COHORT ANALYSIS; CONCEPTION; CONGENITAL MALFORMATION; DENMARK; DIABETES MELLITUS; DRUG EXPOSURE; DRUG USE; FEMALE; FETUS DISTRESS; FIRST TRIMESTER PREGNANCY; GESTATIONAL AGE; HOSPITAL READMISSION; HUMAN; ICD-10; LOW BIRTH WEIGHT; MAJOR CLINICAL STUDY; MAJOR DEPRESSION; MENSTRUAL CYCLE; MENTAL HEALTH CARE; META ANALYSIS; NETHERLANDS; NEWBORN MORBIDITY; OBSTETRIC DELIVERY; ONTARIO; POSTPARTUM HEMORRHAGE; PREECLAMPSIA; PREGNANCY; PREGNANCY COMPLICATION; PREGNANT WOMAN; PREMATURE LABOR; PREVALENCE; PRIORITY JOURNAL; RISK FACTOR; SMALL FOR DATE INFANT; SWEDEN; UNITED KINGDOM; UNITED STATES; EUROPE; GLOBAL HEALTH; NEWBORN;

ADULT; BIPOLAR DISORDER; COHORT STUDIES; DEPRESSIVE DISORDER, MAJOR; EUROPE; FEMALE; GLOBAL HEALTH; HUMANS; INFANT, NEWBORN; LITHIUM; ONTARIO; PREGNANCY; PREGNANCY COMPLICATIONS; UNITED STATES;

EID: 85048926855     PISSN: 22150366     EISSN: 22150374     Source Type: Journal    
DOI: 10.1016/S2215-0366(18)30180-9     Document Type: Article

References (31)

1. Gentile, S, Lithium in pregnancy: the need to treat, the duty to ensure safety. Expert Opin Drug Saf 11 (2012), 425–437.
2. Oruch, R, Elderbi, MA, Khattab, HA, Pryme, IF, Lund, A, Lithium: a review of pharmacology, clinical uses, and toxicity. Eur J Pharmacol 740 (2014), 464–473.
3. Geddes, JR, Miklowitz, DJ, Treatment of bipolar disorder. Lancet 381 (2013), 1672–1682.
4. Cipriani, A, Hawton, K, Stockton, S, Geddes, JR, Lithium in the prevention of suicide in mood disorders: updated systematic review and meta-analysis. BMJ, 346, 2013, f3646.
5. National Insitute of Health and Care Excellence, Depression in adults: recognition and management. London: National Insitute of Health and Care Excellence, 2016. https://www.nice.org.uk/guidance/cg90, 2018. (Accessed 10 May 2018)
6. Barnes, TR, Evidence-based guidelines for the pharmacological treatment of schizophrenia: recommendations from the British Association for Psychopharmacology. J Psychopharmacol 25 (2011), 567–620.
7. Merikangas, KR, Akiskal, HS, Angst, J, et al. Lifetime and 12-month prevalence of bipolar spectrum disorder in the National Comorbidity Survey replication. Arch Gen Psychiatry 64 (2007), 543–552.
8. Laursen, TM, Munk-Olsen, T, Reproductive patterns in psychotic patients. Schizophr Res 121 (2010), 234–240.
9. Wesseloo, R, Kamperman, AM, Munk-Olsen, T, Pop, VJ, Kushner, SA, Bergink, V, Risk of postpartum relapse in bipolar disorder and postpartum psychosis: a systematic review and meta-analysis. Am J Psychiatry 173 (2016), 117–127.
10. Viguera, AC, Whitfield, T, Baldessarini, RJ, et al. Risk of recurrence in women with bipolar disorder during pregnancy: prospective study of mood stabilizer discontinuation. Am J Psychiatry 164 (2007), 1817–1824.
11. Chen, J, Han, M, Manisastry, SM, et al. Molecular effects of lithium exposure during mouse and chick gastrulation and subsequent valve dysmorphogenesis. Birth Defects Res A Clin Mol Teratol 82 (2008), 508–518.
12. Giles, JJ, Bannigan, JG, Teratogenic and developmental effects of lithium. Curr Pharm Des 12 (2006), 1531–1541.
13. Diav-Citrin, O, Shechtman, S, Tahover, E, et al. Pregnancy outcome following in utero exposure to lithium: a prospective, comparative, observational study. Am J Psychiatry 171 (2014), 785–794.
14. Patorno, E, Huybrechts, KF, Bateman, BT, et al. Lithium use in pregnancy and the risk of cardiac malformations. N Engl J Med 376 (2017), 2245–2254.
15. Schou, M, Goldfield, MD, Weinstein, MR, Villeneuve, A, Lithium and pregnancy. I. Report from the Register of Lithium Babies. BMJ 2 (1973), 135–136.
16. Nora, JJ, Nora, AH, Toews, WH, Letter: Lithium, Ebstein's anomaly, and other congenital heart defects. Lancet 2 (1974), 594–595.
17. Troyer, WA, Pereira, GR, Lannon, RA, Belik, J, Yoder, MC, Association of maternal lithium exposure and premature delivery. J Perinatol 13 (1993), 123–127.
18. Newport, DJ, Viguera, AC, Beach, AJ, Ritchie, JC, Cohen, LS, Stowe, ZN, Lithium placental passage and obstetrical outcome: implications for clinical management during late pregnancy. Am J Psychiatry 162 (2005), 2162–2170.
19. Petersen, I, McCrea, RL, Sammon, CJ, et al. Risks and benefits of psychotropic medication in pregnancy: cohort studies based on UK electronic primary care health records. Health Technol Assess 20 (2016), 1–176.
20. McKnight, RF, Adida, M, Budge, K, Stockton, S, Goodwin, GM, Geddes, JR, Lithium toxicity profile: a systematic review and meta-analysis. Lancet 379 (2012), 721–728.
21. Osiro, S, Tiwari, KJ, Mathenge, N, Rodriguez, JR, Tubbs, RS, Loukas, M, When lithium hurts: a look at Ebstein anomaly. Cardiol Rev 21 (2013), 257–263.
22. European Surveillance of Congenital Anomalies, Complete EUROCAT guide 1.4 and reference documents. European Surveillance of Congenital Anomalies, 2013. http://www.eurocat-network.eu/aboutus/datacollection/guidelinesforregistration/guide1_4, 2016. (Accessed 23 April 2016)
23. Nyaga, VN, Arbyn, M, Aerts, M, Metaprop: a Stata command to perform meta-analysis of binomial data. Arch Public Health, 72, 2014, 39.
24. Källén, B, Tandberg, A, Lithium and pregnancy. A cohort study on manic-depressive women. Acta Psychiatr Scand 68 (1983), 134–139.
25. Liew, Z, Olsen, J, Cui, X, Ritz, B, Arah, OA, Bias from conditioning on live birth in pregnancy cohorts: an illustration based on neurodevelopment in children after prenatal exposure to organic pollutants. Int J Epidemiol 44 (2015), 345–354.
26. McCrea, RL, Nazareth, I, Evans, SJ, et al. Lithium prescribing during pregnancy: a UK primary care database study. PLoS One, 10, 2015, e0121024.
27. Bodén, R, Lundgren, M, Brandt, L, Reutfors, J, Andersen, M, Kieler, H, Risks of adverse pregnancy and birth outcomes in women treated or not treated with mood stabilisers for bipolar disorder: population based cohort study. BMJ, 345, 2012, e7085.
28. Weinstein, MR, Goldfield, M, Cardiovascular malformations with lithium use during pregnancy. Am J Psychiatry 132 (1975), 529–531.
29. Boyle, B, Garne, E, Loane, M, et al. The changing epidemiology of Ebstein's anomaly and its relationship with maternal mental health conditions: a European registry-based study. Cardiol Young 27 (2017), 677–685.
30. Cohen, LS, Friedman, JM, Jefferson, JW, Johnson, EM, Weiner, ML, A reevaluation of risk of in utero exposure to lithium. JAMA 271 (1994), 146–150.
31. Yacobi, S, Ornoy, A, Is lithium a real teratogen? What can we conclude from the prospective versus retrospective studies? A review. Isr J Psychiatry Relat Sci 45 (2008), 95–106.