Indiplon is hydrolyzed by arylacetamide deacetylase in human liver

Drug Metabolism and Disposition

Volumn 42, Issue 4, 2014, Pages 751-758

  Shimizu, Mai ^a   Fukami, Tatsuki ^a   Ito, Yusuke ^a   Kurokawa, Takaya ^a   Kariya, Motoki ^a   Nakajima, Miki ^a   Yokoi, Tsuyoshi ^a  

^a KANAZAWA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ARYLACETAMIDE DEACETYLASE; CARBOXYLESTERASE; DIGITONIN; DRUG METABOLIZING ENZYME; FLUTAMIDE; INDIPLON; PHENACETIN; RIFAMPICIN; TELMISARTAN; UNCLASSIFIED DRUG; VINBLASTINE;

ALLELE; ARTICLE; CATALYSIS; DRUG ACTIVITY; DRUG HYDROLYSIS; DRUG STRUCTURE; ENZYME ACTIVITY; FEMALE; HOMOZYGOSITY; HUMAN; HUMAN TISSUE; LIVER CYTOSOL; LIVER MICROSOME; MALE; PRIORITY JOURNAL;

ADULT; ANIMALS; BENZODIAZEPINES; BIOTRANSFORMATION; CARBOXYLESTERASE; CARBOXYLIC ESTER HYDROLASES; CERCOPITHECUS AETHIOPS; COS CELLS; CYTOSOL; FEMALE; HUMANS; HYDROLYSIS; HYPNOTICS AND SEDATIVES; MALE; MICROSOMES, LIVER; MIDDLE AGED; POLYMORPHISM, GENETIC; SUBSTRATE SPECIFICITY; THIOPHENES; YOUNG ADULT;

EID: 85047689260     PISSN: 00909556     EISSN: 1521009X     Source Type: Journal    
DOI: 10.1124/dmd.113.056184     Document Type: Article

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