Characterization of the effect of penehyclidine hydrochloride on muscarinic receptor subtypes mediating the contraction of guinea-pig isolated gastrointestinal smooth muscle

Journal of Pharmacy and Pharmacology

Volumn 61, Issue 7, 2009, Pages 949-952

  Xiao, Hong Tao ^a,c   Liao, Zhi ^a   Meng, Xian Min ^b,c   Yan, Xiao Yan ^c,d   Chen, Shu Jie ^c   Mo, Zheng Ji ^c  

^a SICHUAN PROVINCIAL PEOPLE'S HOSPITAL   (China)

^b FUDAN UNIVERSITY   (China)

^c SICHUAN UNIVERSITY   (China)

^d CHENGDU MEDICAL COLLEGE   (China)

Author keywords

cAMP; Guinea pig gastrointestinal smooth muscle; Muscarinic receptor; Penehyclidine hydrochloride; Selective antagonist

Indexed keywords

ACETYLCHOLINE; ATROPINE; CYCLIC AMP; MUSCARINIC RECEPTOR; MUSCLE RELAXANT AGENT; PENEHYCLIDINE; UNCLASSIFIED DRUG; MUSCARINIC M2 RECEPTOR; MUSCARINIC M3 RECEPTOR; QUINUCLIDINE DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; FEMALE; GUINEA PIG; ISOLATION PROCEDURE; MALE; MUSCLE CONTRACTION; MUSCLE RELAXATION; NONHUMAN; RADIOIMMUNOASSAY; SMOOTH MUSCLE; ANIMAL; BIOSYNTHESIS; DOSE RESPONSE; DRUG ANTAGONISM; GASTROINTESTINAL TRACT; IN VITRO STUDY; PHYSIOLOGY; RADIOASSAY;

ACETYLCHOLINE; ANIMALS; ATROPINE; CYCLIC AMP; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; GASTROINTESTINAL TRACT; GUINEA PIGS; MALE; MUSCLE CONTRACTION; MUSCLE RELAXATION; MUSCLE, SMOOTH; QUINUCLIDINES; RADIOLIGAND ASSAY; RECEPTOR, MUSCARINIC M2; RECEPTOR, MUSCARINIC M3;

EID: 85047685978     PISSN: 00223573     EISSN: None     Source Type: Journal    
DOI: 10.1211/jpp.61.07.0015     Document Type: Article

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