Inhibition of ERα-mediated trans-activation of human coagulation factor XII gene by heteromeric transcription factor NF-Y

Endocrinology

Volumn 142, Issue 8, 2001, Pages 3380-3388

  Farsetti, Antonella ^a,e   Narducci, Michela ^b,e   Moretti, Fabiola ^a,e   Nanni, Simona ^e   Mantovani, Roberto ^c   Sacchi, Ada ^e   Pontecorvi, Alfredo ^d,e  

^a CNR   (Italy)

^b SAPIENZA UNIVERSITY OF ROME   (Italy)

^c UNIVERSITY OF MODENA AND REGGIO EMILIA   (Italy)

^d CATHOLIC UNIVERSITY   (Italy)

^e REGINA ELENA NATIONAL CANCER INSTITUTE   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

BLOOD CLOTTING FACTOR 12; CCAAT ENHANCER BINDING PROTEIN; ESTROGEN RECEPTOR ALPHA; NUCLEAR FACTOR Y; PROTEIN SUBUNIT; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG; CCAAT BINDING FACTOR; DNA; ESTRADIOL; ESTROGEN RECEPTOR; ISOPROTEIN;

3' UNTRANSLATED REGION; ANIMAL CELL; ARTICLE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; EMBRYO; ESTROGEN RESPONSIVE ELEMENT; GENE DELETION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; LIGAND BINDING; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DNA BINDING; SEQUENCE HOMOLOGY; TRANSACTIVATION; TRANSCRIPTION REGULATION; ANIMAL; CELL CULTURE; CELL STRAIN 3T3; DRUG EFFECT; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; GENETICS; METABOLISM; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; PHYSIOLOGY; PROTEIN TERTIARY STRUCTURE;

3T3 CELLS; ANIMALS; BASE SEQUENCE; CCAAT-BINDING FACTOR; DNA; ESTRADIOL; ESTROGEN RECEPTOR ALPHA; FACTOR XII; GENE EXPRESSION REGULATION; HUMANS; MICE; MOLECULAR SEQUENCE DATA; PROMOTER REGIONS (GENETICS); PROTEIN ISOFORMS; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, ESTROGEN; TRANS-ACTIVATION (GENETICS); TRANSCRIPTION, GENETIC; TUMOR CELLS, CULTURED;

EID: 85047683435     PISSN: 00137227     EISSN: None     Source Type: Journal    
DOI: 10.1210/endo.142.8.8345     Document Type: Article

References (53)

1. Activation and inhibition of factor XII (Hageman factor) in vivo
2. Surface mediated defense reaction. The plasma contact activation system
3. The molecular basis of blood coagulation
4. Characterization of human blood coagulation factor XII cDNA
5. Interaction of type I plasminogen inhibitor with the enzime of the contact activation system
6. Factor XII clotting activity and antigen levels in patients with thromboembolic disease
7. The ormonal control of the synthesis of Hageman (factor XII)
8. Enhanced expression of factor XII (Hageman factor) in isolated livers of estrogen- and prolactin-treated rats
9. Molecular basis of estrogen regulation of Hageman factor XII gene expression
10. Steroid hormone receptors: Interaction with deoxyribonucleic acid and transcription factors
11. Increasing the complexity of coactivation in nuclear receptor signaling
12. An estrogen receptor-selective coregulator that potentiates the effectiveness of antiestrogens and represses the activity of estrogens
13. Regulation of glucocorticoid and estrogen receptor activity by phosphorylation
14. Steroid receptor co-activator-1 is a histone acetyltransferase
15. The transcriptional co-activator p300 and CBP are histone acetyltransferase
16. Fatty acyl-CoA thioesters are ligands of hepatic nuclear factor-4alpha
17. Liver-enriched transcription factor HNF-4 is a novel member of the steroid hormone receptor superfamily
18. Orphan receptor hepatocyte nuclear factor-4 antagonizes estrogen receptor α-mediated induction of human coagulation factor XII gene
19. Estrogen control of progesterone receptor in human breast cancer
20. Functional characterization and receptor binding studies of the malic enzyme thyroid hormone response element
21. Molecular basis of thyroid hormone regulation of myelin basic protein gene expression in rodent brain
22. Structure and growth-dependent regulation of the human cyclin b1 promoter
23. Identification of estrogen-responsive DNA sequences by transient expression experiments in a human breast cancer cell line
24. Characterization of myelin basic protein thyroid hormone response element and its function in the context of native and heterologous promoter
25. Cloning and expression of human NF-YC
26. Monoclonal antibodies to NF-Y define its function in MHC class II and albumin gene transcription
27. Dominant negative analogs of NF-YA
28. Conservation and divergence of NF-YA
29. Dissection of the NF-Y transcriptional activation potential
30. A versatile in vivo and in vitro eukaryotic expression vector for protein engineering
31. Transcriptional regulation of the ferritin heavy-chain gene: The activity of the CCAAT binding factor NF-Y is modulated in heine-treated Friend leukemia cells and during monocyte-to-macrophage differentiation
32. A multiplicity of CCAAT box-binding proteins
33. CCAAT binding NF-Y-TBP interactions: NF-YB and NF-YC require short domains adjacent to their histone fold motifs for association with TBP basic residues
34. Dose-dependent effects of postmenopausal estrogen and progestin on antithrombin III and factor XII
35. Mechanisms of disease: The protective effects of estrogen on the cardiovascular system
36. Co-evolution from yeast to mouse: cDNA cloning of the two NF-Y (CP-1/CBF) subunits
37. Three different polypeptides are necessary for DNA binding of the mammalian heteromeric CCAAT binding factor
38. Recombinant rat CBF-C, the third subunit of CBF/NF-Y, allows formation of a protein-DNA complex with CBF-A and CBF-B, and with yeast HAP2 and HAP3
39. Cloning of yeast HAP5: A novel subunit of a heterotrimeric complex required for CCAAT binding
40. Weight matrix descriptions of four eukaryotic RNA polymerase II promoter elements derived from 502 unrelated promoter sequences
41. The molecular biology of the CCAAT-binding factor NF-Y
42. Sterol regulation of 3-hydroxy-3-methylglutaryl-coenzyme A synthase gene through a direct interaction between sterol regulatory element binding protein and the trimeric CCAAT-binding factor/nuclear factor Y
43. Synergistic activation of transcription by nuclear factor Y and sterol regulatory element binding protein
44. A ubiquitous factor is required for C/EBP-related proteins to form stable transcription complexes on an albumin promoter segment in vitro
45. Positive regulation of the human macrophage stimulating protein gene transcription
46. 1 protein and the CCAAT binding protein NF-Y
47. Interaction between the two ubiquitously expressed transcription factor NF-Y and Sp1
48. Transcriptional regulation of the MDR1 gene by histone acetyltransferase and deacetylase is mediated by NF-Y
49. NF-Y is associated with the histone acetyltransferases GCN5 and P/CAF
50. The B subunit of the CAAT-binding factor NF-Y binds the central segment of the co-activator p300
51. P/CAF associates with cyclin D1 and potentiates its activation of the estrogen receptor
52. p300 is a component of an estrogen receptor coactivator complex
53. 11110 component of the Drosophila TFIID complex