메뉴 건너뛰기




Volumn 35, Issue 6, 2018, Pages 875-885

Effects of the SGLT-2 Inhibitor Empagliflozin on Renal Tissue Oxygenation in Non-Diabetic Subjects: A Randomized, Double-Blind, Placebo-Controlled Study Protocol

Author keywords

BOLD MRI; Empagliflozin; Endocrinology; SGLT 2

Indexed keywords

EMPAGLIFLOZIN; PLACEBO; ANTIDIABETIC AGENT; BENZHYDRYL DERIVATIVE;

EID: 85047421072     PISSN: 0741238X     EISSN: 18658652     Source Type: Journal    
DOI: 10.1007/s12325-018-0708-y     Document Type: Article
Times cited : (14)

References (27)
  • 1
    • 84944800184 scopus 로고    scopus 로고
    • Empagliflozin, cardiovascular outcomes, and mortality in type 2 diabetes
    • PID: 26378978
    • Zinman B, Wanner C, Lachin JM, et al. Empagliflozin, cardiovascular outcomes, and mortality in type 2 diabetes. N Engl J Med. 2015;373(22):2117–28.
    • (2015) N Engl J Med , vol.373 , Issue.22 , pp. 2117-2128
    • Zinman, B.1    Wanner, C.2    Lachin, J.M.3
  • 2
    • 84994180780 scopus 로고    scopus 로고
    • Empagliflozin and progression of kidney disease in type 2 diabetes
    • PID: 27806236
    • Wanner C, Inzucchi SE, Zinman B. Empagliflozin and progression of kidney disease in type 2 diabetes. N Engl J Med. 2016;375(18):1801–2.
    • (2016) N Engl J Med , vol.375 , Issue.18 , pp. 1801-1802
    • Wanner, C.1    Inzucchi, S.E.2    Zinman, B.3
  • 4
    • 0027517659 scopus 로고
    • The effect of angiotensin-converting-enzyme inhibition on diabetic nephropathy. The Collaborative Study Group
    • PID: 8413456
    • Lewis EJ, Hunsicker LG, Bain RP, Rohde RD. The effect of angiotensin-converting-enzyme inhibition on diabetic nephropathy. The Collaborative Study Group. N Engl J Med. 1993;329(20):1456–62.
    • (1993) N Engl J Med , vol.329 , Issue.20 , pp. 1456-1462
    • Lewis, E.J.1    Hunsicker, L.G.2    Bain, R.P.3    Rohde, R.D.4
  • 5
    • 0035922441 scopus 로고    scopus 로고
    • Effects of losartan on renal and cardiovascular outcomes in patients with type 2 diabetes and nephropathy
    • PID: 11565518
    • Brenner BM, Cooper ME, de Zeeuw D, et al. Effects of losartan on renal and cardiovascular outcomes in patients with type 2 diabetes and nephropathy. N Engl J Med. 2001;345(12):861–9.
    • (2001) N Engl J Med , vol.345 , Issue.12 , pp. 861-869
    • Brenner, B.M.1    Cooper, M.E.2    de Zeeuw, D.3
  • 6
    • 0035922447 scopus 로고    scopus 로고
    • Renoprotective effect of the angiotensin-receptor antagonist irbesartan in patients with nephropathy due to type 2 diabetes
    • PID: 11565517
    • Lewis EJ, Hunsicker LG, Clarke WR, et al. Renoprotective effect of the angiotensin-receptor antagonist irbesartan in patients with nephropathy due to type 2 diabetes. N Engl J Med. 2001;345(12):851–60.
    • (2001) N Engl J Med , vol.345 , Issue.12 , pp. 851-860
    • Lewis, E.J.1    Hunsicker, L.G.2    Clarke, W.R.3
  • 7
    • 85065599284 scopus 로고    scopus 로고
    • Standards of medical care in diabetes-2017: summary of revisions
    • ADA. Standards of medical care in diabetes-2017: summary of revisions. Diabetes Care. 2017;40(Suppl 1):S4–5.
    • (2017) Diabetes Care , vol.40 , pp. S4-S5
  • 8
    • 84982113684 scopus 로고    scopus 로고
    • 2016 European guidelines on cardiovascular disease prevention in clinical practice: the Sixth Joint Task Force of the European Society of Cardiology and Other Societies on Cardiovascular Disease Prevention in Clinical Practice (constituted by representatives of 10 societies and by invited experts) developed with the special contribution of the European Association for Cardiovascular Prevention & Rehabilitation (EACPR)
    • PID: 27222591
    • Piepoli MF, Hoes AW, Agewall S, et al. 2016 European guidelines on cardiovascular disease prevention in clinical practice: the Sixth Joint Task Force of the European Society of Cardiology and Other Societies on Cardiovascular Disease Prevention in Clinical Practice (constituted by representatives of 10 societies and by invited experts) developed with the special contribution of the European Association for Cardiovascular Prevention & Rehabilitation (EACPR). Eur Heart J. 2016;37(29):2315–81.
    • (2016) Eur Heart J , vol.37 , Issue.29 , pp. 2315-2381
    • Piepoli, M.F.1    Hoes, A.W.2    Agewall, S.3
  • 9
    • 84891865819 scopus 로고    scopus 로고
    • Characterization of renal glucose reabsorption in response to dapagliflozin in healthy subjects and subjects with type 2 diabetes
    • PID: 23735727
    • DeFronzo RA, Hompesch M, Kasichayanula S, et al. Characterization of renal glucose reabsorption in response to dapagliflozin in healthy subjects and subjects with type 2 diabetes. Diabetes Care. 2013;36(10):3169–76.
    • (2013) Diabetes Care , vol.36 , Issue.10 , pp. 3169-3176
    • DeFronzo, R.A.1    Hompesch, M.2    Kasichayanula, S.3
  • 10
    • 84885171560 scopus 로고    scopus 로고
    • The clinical efficacy and safety of sodium glucose cotransporter-2 inhibitors in adults with type 2 diabetes mellitus
    • PID: 23744749
    • Riser Taylor S, Harris KB. The clinical efficacy and safety of sodium glucose cotransporter-2 inhibitors in adults with type 2 diabetes mellitus. Pharmacotherapy. 2013;33(9):984–99.
    • (2013) Pharmacotherapy , vol.33 , Issue.9 , pp. 984-999
    • Riser Taylor, S.1    Harris, K.B.2
  • 11
    • 84893214045 scopus 로고    scopus 로고
    • Renal hemodynamic effect of sodium-glucose cotransporter 2 inhibition in patients with type 1 diabetes mellitus
    • PID: 24334175
    • Cherney DZ, Perkins BA, Soleymanlou N, et al. Renal hemodynamic effect of sodium-glucose cotransporter 2 inhibition in patients with type 1 diabetes mellitus. Circulation. 2014;129(5):587–97.
    • (2014) Circulation , vol.129 , Issue.5 , pp. 587-597
    • Cherney, D.Z.1    Perkins, B.A.2    Soleymanlou, N.3
  • 12
    • 0042422126 scopus 로고    scopus 로고
    • Tubuloglomerular feedback and the control of glomerular filtration rate
    • PID: 12869618
    • Vallon V. Tubuloglomerular feedback and the control of glomerular filtration rate. News Physiol Sci. 2003;18:169–74.
    • (2003) News Physiol Sci , vol.18 , pp. 169-174
    • Vallon, V.1
  • 14
    • 84975840750 scopus 로고    scopus 로고
    • Can a shift in fuel energetics explain the beneficial cardiorenal outcomes in the EMPA-REG OUTCOME study? A unifying hypothesis
    • PID: 27289124
    • Mudaliar S, Alloju S, Henry RR. Can a shift in fuel energetics explain the beneficial cardiorenal outcomes in the EMPA-REG OUTCOME study? A unifying hypothesis. Diabetes Care. 2016;39(7):1115–22.
    • (2016) Diabetes Care , vol.39 , Issue.7 , pp. 1115-1122
    • Mudaliar, S.1    Alloju, S.2    Henry, R.R.3
  • 15
    • 0029640011 scopus 로고
    • Hypoxia of the renal medulla—its implications for disease
    • PID: 7845430
    • Brezis M, Rosen S. Hypoxia of the renal medulla—its implications for disease. N Engl J Med. 1995;332(10):647–55.
    • (1995) N Engl J Med , vol.332 , Issue.10 , pp. 647-655
    • Brezis, M.1    Rosen, S.2
  • 17
    • 84861651942 scopus 로고    scopus 로고
    • Noninvasive evaluation of renal oxygenation in diabetic nephropathy by BOLD-MRI
    • PID: 21470811
    • Yin WJ, Liu F, Li XM, et al. Noninvasive evaluation of renal oxygenation in diabetic nephropathy by BOLD-MRI. Eur J Radiol. 2012;81(7):1426–31.
    • (2012) Eur J Radiol , vol.81 , Issue.7 , pp. 1426-1431
    • Yin, W.J.1    Liu, F.2    Li, X.M.3
  • 18
    • 33644999688 scopus 로고    scopus 로고
    • Evaluation of intra-renal oxygenation by BOLD MRI
    • PID: 16543757
    • Prasad PV. Evaluation of intra-renal oxygenation by BOLD MRI. Nephron Clin Pract. 2006;103(2):c58–65.
    • (2006) Nephron Clin Pract , vol.103 , Issue.2 , pp. c58-c65
    • Prasad, P.V.1
  • 19
    • 84899718664 scopus 로고    scopus 로고
    • Determinants of renal tissue oxygenation as measured with BOLD-MRI in chronic kidney disease and hypertension in humans
    • PID: 24760031
    • Pruijm M, Hofmann L, Piskunowicz M, et al. Determinants of renal tissue oxygenation as measured with BOLD-MRI in chronic kidney disease and hypertension in humans. PLoS One. 2014;9(4):e95895.
    • (2014) PLoS One , vol.9 , Issue.4
    • Pruijm, M.1    Hofmann, L.2    Piskunowicz, M.3
  • 20
    • 77951460727 scopus 로고    scopus 로고
    • Effect of sodium loading/depletion on renal oxygenation in young normotensive and hypertensive men
    • PID: 20308608
    • Pruijm M, Hofmann L, Maillard M, et al. Effect of sodium loading/depletion on renal oxygenation in young normotensive and hypertensive men. Hypertension. 2010;55(5):1116–22.
    • (2010) Hypertension , vol.55 , Issue.5 , pp. 1116-1122
    • Pruijm, M.1    Hofmann, L.2    Maillard, M.3
  • 21
    • 84884529387 scopus 로고    scopus 로고
    • Effect of dark chocolate on renal tissue oxygenation as measured by BOLD-MRI in healthy volunteers
    • PID: 23557792
    • Pruijm M, Hofmann L, Charollais-Thoenig J, et al. Effect of dark chocolate on renal tissue oxygenation as measured by BOLD-MRI in healthy volunteers. Clin Nephrol. 2013;80(3):211–7.
    • (2013) Clin Nephrol , vol.80 , Issue.3 , pp. 211-217
    • Pruijm, M.1    Hofmann, L.2    Charollais-Thoenig, J.3
  • 22
    • 84962339296 scopus 로고    scopus 로고
    • Euglycemic diabetic ketoacidosis: a potential complication of treatment with sodium-glucose cotransporter 2 inhibition
    • PID: 26078479
    • Peters AL, Buschur EO, Buse JB, Cohan P, Diner JC, Hirsch IB. Euglycemic diabetic ketoacidosis: a potential complication of treatment with sodium-glucose cotransporter 2 inhibition. Diabetes Care. 2015;38(9):1687–93.
    • (2015) Diabetes Care , vol.38 , Issue.9 , pp. 1687-1693
    • Peters, A.L.1    Buschur, E.O.2    Buse, J.B.3    Cohan, P.4    Diner, J.C.5    Hirsch, I.B.6
  • 23
    • 77955515855 scopus 로고    scopus 로고
    • Effects of the peroxisome proliferator-activated receptor (PPAR)-gamma agonist pioglitazone on renal and hormonal responses to salt in diabetic and hypertensive individuals
    • PID: 20414637
    • Zanchi A, Maillard M, Jornayvaz FR, et al. Effects of the peroxisome proliferator-activated receptor (PPAR)-gamma agonist pioglitazone on renal and hormonal responses to salt in diabetic and hypertensive individuals. Diabetologia. 2010;53(8):1568–75.
    • (2010) Diabetologia , vol.53 , Issue.8 , pp. 1568-1575
    • Zanchi, A.1    Maillard, M.2    Jornayvaz, F.R.3
  • 24
    • 1642302410 scopus 로고    scopus 로고
    • Effects of the peroxisomal proliferator-activated receptor-gamma agonist pioglitazone on renal and hormonal responses to salt in healthy men
    • PID: 15001599
    • Zanchi A, Chiolero A, Maillard M, Nussberger J, Brunner HR, Burnier M. Effects of the peroxisomal proliferator-activated receptor-gamma agonist pioglitazone on renal and hormonal responses to salt in healthy men. J Clin Endocrinol Metab. 2004;89(3):1140–5.
    • (2004) J Clin Endocrinol Metab , vol.89 , Issue.3 , pp. 1140-1145
    • Zanchi, A.1    Chiolero, A.2    Maillard, M.3    Nussberger, J.4    Brunner, H.R.5    Burnier, M.6
  • 25
    • 84884816112 scopus 로고    scopus 로고
    • Heritability, determinants and reference values of renal length: a family-based population study
    • PID: 23712436
    • Pruijm M, Ponte B, Ackermann D, et al. Heritability, determinants and reference values of renal length: a family-based population study. Eur Radiol. 2013;23(10):2899–905.
    • (2013) Eur Radiol , vol.23 , Issue.10 , pp. 2899-2905
    • Pruijm, M.1    Ponte, B.2    Ackermann, D.3
  • 26
    • 84887072459 scopus 로고    scopus 로고
    • Safety, tolerability, pharmacokinetics, and pharmacodynamics of multiple rising doses of empagliflozin in patients with type 2 diabetes mellitus
    • PID: 23838841
    • Heise T, Seman L, Macha S, Jones P, Marquart A, Pinnetti S, et al. Safety, tolerability, pharmacokinetics, and pharmacodynamics of multiple rising doses of empagliflozin in patients with type 2 diabetes mellitus. Diabetes Ther. 2013;4(2):331–45.
    • (2013) Diabetes Ther , vol.4 , Issue.2 , pp. 331-345
    • Heise, T.1    Seman, L.2    Macha, S.3
  • 27
    • 85040101855 scopus 로고    scopus 로고
    • Reduction of cortical oxygenation in chronic kidney disease: Evidence obtained with a new analysis method of blood oxygenation level-dependent magnetic resonance imaging
    • Milani B, Ansaloni A, Sousa-Guimaraes S, et al. Reduction of cortical oxygenation in chronic kidney disease: evidence obtained with a new analysis method of blood oxygenation level-dependent magnetic resonance imaging. Nephrol Dial Transplant. 2017;32(12):2097–105.
    • (2017) Nephrol Dial Transplant , vol.32 , Issue.12 , pp. 2097-2105
    • Milani, B.1    Ansaloni, A.2    Sousa-Guimaraes, S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.