Ab initio solution of macromolecular crystal structures without direct methods

Proceedings of the National Academy of Sciences of the United States of America

Volumn 114, Issue 14, 2017, Pages 3637-3641

  McCoy, Airlie J ^a   Oeffner, Robert D ^a   Wrobel, Antoni G ^a   Ojala, Juha R M ^b   Tryggvason, Karl ^b,c   Lohkamp, Bernhard ^b   Read, Randy J ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b KAROLINSKA INSTITUTE   (Sweden)

^c NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

Author keywords

Ab initio phasing; Likelihood; Macromolecular crystallography; Molecular replacement; Shisa

Indexed keywords

ALDEHYDE REDUCTASE; PROTEIN; SHISA3 PROTEIN; UNCLASSIFIED DRUG;

AB INITIO CALCULATION; AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; ARTICLE; ATOM; CRYSTAL STRUCTURE; CRYSTALLOGRAPHY; DIFFRACTION; ELECTRON; MACROMOLECULE; MATHEMATICAL MODEL; PREDICTION; PRIORITY JOURNAL; PROTEIN DATA BANK; SIGNAL NOISE RATIO; ALGORITHM; BIOLOGY; CHEMISTRY; MOLECULAR MODEL; PROCEDURES; PROTEIN CONFORMATION; STATISTICAL MODEL; X RAY CRYSTALLOGRAPHY;

ALGORITHMS; COMPUTATIONAL BIOLOGY; CRYSTALLOGRAPHY, X-RAY; LIKELIHOOD FUNCTIONS; MODELS, MOLECULAR; PROTEIN CONFORMATION; PROTEINS; SIGNAL-TO-NOISE RATIO;

EID: 85047290168     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1701640114     Document Type: Article

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