Disease Heritability Inferred from Familial Relationships Reported in Medical Records

Cell

Volumn 173, Issue 7, 2018, Pages 1692-1704.e11

  Polubriaginof, Fernanda C G ^a   Vanguri, Rami ^a   Quinnies, Kayla ^a   Belbin, Gillian M ^b   Yahi, Alexandre ^a   Salmasian, Hojjat ^a,c   Lorberbaum, Tal ^a   Nwankwo, Victor ^a   Li, Li ^b   Shervey, Mark M ^b   Glowe, Patricia ^b   Ionita Laza, Iuliana ^a,d   Simmerling, Mary ^c,e   Hripcsak, George ^a,c,f   Bakken, Suzanne ^a   Goldstein, David ^a   Kiryluk, Krzysztof ^a   Kenny, Eimear E ^b   Dudley, Joel ^b   Vawdrey, David K ^a,c   Tatonetti, Nicholas P ^a,f   more..

^a Och Spine at New York Presbyterian Hospitals   (United States)

^b MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^c NEW YORK PRESBYTERIAN HOSPITAL   (United States)

^d Cornell University ^*  (United States)

^e WEILL CORNELL MEDICAL COLLEGE   (United States)

^f Observational Health Data Sciences and Informatics   (United States)

Author keywords

data mining; disease heritability; electronic health record; familial relationships; family history; genetics; observational databases

Indexed keywords

HIGH DENSITY LIPOPROTEIN CHOLESTEROL; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; LOW DENSITY LIPOPROTEIN CHOLESTEROL;

ADULT; AGED; ARTICLE; CAUCASIAN; CYSTIC FIBROSIS; DISEASES; ELECTRONIC HEALTH RECORD; FAMILY HISTORY; FEMALE; HEADACHE; HERITABILITY; HUMAN; HYPERCHOLESTEROLEMIA; MAJOR CLINICAL STUDY; MALE; PHENOTYPE; SICKLE CELL ANEMIA; SLEEP DISORDER; VERY ELDERLY; YOUNG ADULT; ALGORITHM; FACTUAL DATABASE; FAMILY RELATION; GENETIC DISORDER; GENETICS; GENOTYPE; PATHOLOGY; PEDIGREE; QUANTITATIVE TRAIT;

ALGORITHMS; DATABASES, FACTUAL; ELECTRONIC HEALTH RECORDS; FAMILY RELATIONS; GENETIC DISEASES, INBORN; GENOTYPE; HUMANS; PEDIGREE; PHENOTYPE; QUANTITATIVE TRAIT, HERITABLE;

EID: 85047185657     PISSN: 00928674     EISSN: 10974172     Source Type: Journal    
DOI: 10.1016/j.cell.2018.04.032     Document Type: Article

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