Indexed keywords
BASIC RESEARCH;
BILE DUCT CARCINOMA;
CRISPR-CAS9 SYSTEM;
DNA END JOINING REPAIR;
DNA SEQUENCE;
DNA TEMPLATE;
DOUBLE STRANDED DNA BREAK;
GENE DELETION;
GENE EDITING;
HUMAN;
LIVER CELL CARCINOMA;
LIVER DISEASE;
LOSS OF FUNCTION MUTATION;
MOUSE MODEL;
MUTANT;
NONHUMAN;
NOTE;
PRIORITY JOURNAL;
TRANSLATIONAL RESEARCH;
TYROSINEMIA;
ANIMAL;
CRISPR CAS SYSTEM;
DISEASE MODEL;
GENETICS;
LIVER TUMOR;
MEDICAL RESEARCH;
MOUSE;
PROCEDURES;
ANIMALS;
BIOMEDICAL RESEARCH;
CRISPR-CAS SYSTEMS;
DISEASE MODELS, ANIMAL;
GENE EDITING;
HUMANS;
LIVER DISEASES;
LIVER NEOPLASMS;
MICE;
TRANSLATIONAL MEDICAL RESEARCH;
1
84913594397
The new frontier of genome engineering with CRISPR-Cas9
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Charpentier, E.2
2
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CRISPR/Cas9: At the cutting edge of hepatology
Pankowicz, F. P. et al. CRISPR/Cas9: At the cutting edge of hepatology. Gut 66, 1329-1340 (2017).
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3
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Methods and applications of CRISPR-mediated base editing in eukaryotic genomes
Hess, G. T. et al. Methods and applications of CRISPR-mediated base editing in eukaryotic genomes. Mol. Cell 68, 26-43 (2017).
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Hess, G.T.1
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Structure-guided chemical modification of guide RNA enables potent non-viral in vivo genome editing
Yin, H. et al. Structure-guided chemical modification of guide RNA enables potent non-viral in vivo genome editing. Nat. Biotechnol. 35, 1179-1187 (2017).
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Nat. Biotechnol. , vol.35
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Yin, H.1
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Applications of the CRISPR-Cas9 system in cancer biology
Sanchez-Rivera, F. J. & Jacks, T. Applications of the CRISPR-Cas9 system in cancer biology. Nat. Rev. Cancer 15, 387-395 (2015).
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Jacks, T.2
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Genome-wide CRISPR screen identifies regulators of mitogen-activated protein kinase as suppressors of liver tumors in mice
Song, C. Q. et al. Genome-wide CRISPR screen identifies regulators of mitogen-activated protein kinase as suppressors of liver tumors in mice. Gastroenterology 152, 1161-1173.e1 (2017).
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Song, C.Q.1
7
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Adenovirus-mediated somatic genome editing of Pten by CRISPR/Cas9 in mouse liver in spite of Cas9-specific immune responses
Wang, D. et al. Adenovirus-mediated somatic genome editing of Pten by CRISPR/Cas9 in mouse liver in spite of Cas9-specific immune responses. Hum. Gene Ther. 26, 432-442 (2015).
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Wang, D.1
8
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GUIDE-seq enables genome-wide profiling of off-target cleavage by CRISPR-Cas nucleases
Tsai, S. Q. et al. GUIDE-seq enables genome-wide profiling of off-target cleavage by CRISPR-Cas nucleases. Nat. Biotechnol. 33, 187-197 (2014).
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Tsai, S.Q.1
9
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In vivo genome editing via CRISPR/Cas9 mediated homology-independent targeted integration
Suzuki, K. et al. In vivo genome editing via CRISPR/Cas9 mediated homology-independent targeted integration. Nature 540, 144-149 (2016).
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Nature , vol.540
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Suzuki, K.1
10
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RNA targeting with CRISPR-Cas13
Abudayyeh, O. O. et al. RNA targeting with CRISPR-Cas13. Nature 550, 280-284 (2017).
(2017)
Nature , vol.550
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Abudayyeh, O.O.1
