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Volumn 14, Issue 10, 2018, Pages 907-917

Sipuleucel-T for the treatment of prostate cancer: Novel insights and future directions

Author keywords

biomarkers; cancer vaccine; castration resistant prostate cancer; immunotherapy; prostate cancer; sipuleucel T

Indexed keywords

ABIRATERONE; ACID PHOSPHATASE PROSTATE ISOENZYME; ATEZOLIZUMAB; BEVACIZUMAB; DNA VACCINE; DOCETAXEL; ENZALUTAMIDE; INDOXIMOD; INTERLEUKIN 7; IPILIMUMAB; NIVOLUMAB; PLACEBO; PROSTATE SPECIFIC ANTIGEN; RADIUM CHLORIDE RA 223; SIPULEUCEL T; ACID PHOSPHATASE; ANTINEOPLASTIC AGENT; CANCER VACCINE; TISSUE EXTRACT; TUMOR MARKER;

EID: 85045473271     PISSN: 14796694     EISSN: 17448301     Source Type: Journal    
DOI: 10.2217/fon-2017-0531     Document Type: Article
Times cited : (119)

References (71)
  • 2
    • 78149358386 scopus 로고    scopus 로고
    • Surveillance Epidemiology and End Results Program. Cancer statistics (2017). www.cancer.gov/about-cancer/understanding/statistics
    • (2017) Cancer Statistics
  • 3
    • 85006187918 scopus 로고    scopus 로고
    • Recent decline in prostate cancer incidence in the United States, by age, stage, and Gleason score
    • Herget KA, Patel DP, Hanson HA, Sweeney C, Lowrance WT. Recent decline in prostate cancer incidence in the United States, by age, stage, and Gleason score. Cancer Med. 5(1), 136-141 (2016).
    • (2016) Cancer Med , vol.5 , Issue.1 , pp. 136-141
    • Herget, K.A.1    Patel, D.P.2    Hanson, H.A.3    Sweeney, C.4    Lowrance, W.T.5
  • 4
    • 84991231538 scopus 로고    scopus 로고
    • 10-year outcomes after monitoring, surgery, or radiotherapy for localized prostate cancer
    • Hamdy FC, Donovan JL, Lane JA et al. 10-year outcomes after monitoring, surgery, or radiotherapy for localized prostate cancer. N. Engl. J. Med. 375(15), 1415-1424 (2016).
    • (2016) N. Engl. J. Med , vol.375 , Issue.15 , pp. 1415-1424
    • Hamdy, F.C.1    Donovan, J.L.2    Lane, J.A.3
  • 5
    • 33748923481 scopus 로고    scopus 로고
    • Use of different definitions of biochemical failure after external beam radiotherapy changes conclusions about relative treatment efficacy for localized prostate cancer
    • Kupelian PA, Mahadevan A, Reddy CA, Reuther AM, Klein EA. Use of different definitions of biochemical failure after external beam radiotherapy changes conclusions about relative treatment efficacy for localized prostate cancer. Urology 68(3), 593-598 (2006).
    • (2006) Urology , vol.68 , Issue.3 , pp. 593-598
    • Kupelian, P.A.1    Mahadevan, A.2    Reddy, C.A.3    Reuther, A.M.4    Klein, E.A.5
  • 6
    • 4143053657 scopus 로고    scopus 로고
    • Cancer progression and survival rates following anatomical radical retropubic prostatectomy in 3, 478 consecutive patients: Long-term results
    • Roehl KA, Han M, Ramos CG, Antenor JA, Catalona WJ. Cancer progression and survival rates following anatomical radical retropubic prostatectomy in 3, 478 consecutive patients: long-term results. J. Urol. 172(3), 910-914 (2004).
    • (2004) J. Urol , vol.172 , Issue.3 , pp. 910-914
    • Roehl, K.A.1    Han, M.2    Ramos, C.G.3    Antenor, J.A.4    Catalona, W.J.5
  • 7
    • 84877068636 scopus 로고    scopus 로고
    • Management of biochemically recurrent prostate cancer after local therapy: Evolving standards of care and new directions
    • Paller CJ, Antonarakis ES. Management of biochemically recurrent prostate cancer after local therapy: evolving standards of care and new directions. Clin. Adv. Hematol. Oncol. HO 11(1), 14-23 (2013).
    • (2013) Clin. Adv. Hematol. Oncol. HO , vol.11 , Issue.1 , pp. 14-23
    • Paller, C.J.1    Antonarakis, E.S.2
  • 8
    • 84939864061 scopus 로고    scopus 로고
    • Chemohormonal therapy in metastatic hormone-sensitive prostate cancer
    • Sweeney CJ, Chen YH, Carducci M et al. Chemohormonal therapy in metastatic hormone-sensitive prostate cancer. N. Engl. J. Med. 373(8), 737-746 (2015).
    • (2015) N. Engl. J. Med , vol.373 , Issue.8 , pp. 737-746
    • Sweeney, C.J.1    Chen, Y.H.2    Carducci, M.3
  • 9
    • 84866948935 scopus 로고    scopus 로고
    • Abiraterone acetate for treatment of metastatic castration-resistant prostate cancer: Final overall survival analysis of the COU-AA-301 randomised, double-blind, placebo-controlled Phase 3 study
    • Fizazi K, Scher HI, Molina A et al. Abiraterone acetate for treatment of metastatic castration-resistant prostate cancer: final overall survival analysis of the COU-AA-301 randomised, double-blind, placebo-controlled Phase 3 study. Lancet Oncol. 13(10), 983-992 (2012).
    • (2012) Lancet Oncol , vol.13 , Issue.10 , pp. 983-992
    • Fizazi, K.1    Scher, H.I.2    Molina, A.3
  • 10
    • 85045426377 scopus 로고    scopus 로고
    • National Cancer Institute. Drugs approved for prostate cancer (2014). www.cancer.gov/about-cancer/treatment/drugs/prostate
    • (2014) Drugs Approved for Prostate Cancer
  • 11
    • 85006925431 scopus 로고    scopus 로고
    • Sequencing treatment for castration-resistant prostate cancer
    • Handy CE, Antonarakis ES. Sequencing treatment for castration-resistant prostate cancer. Curr. Treat. OptionsOncol. 17(12), 64 (2016).
    • (2016) Curr. Treat. OptionsOncol , vol.17 , Issue.12 , pp. 64
    • Handy, C.E.1    Antonarakis, E.S.2
  • 13
    • 84890407875 scopus 로고    scopus 로고
    • An updated view of the intracellular mechanisms regulating cross-presentation
    • Nair-Gupta P, Blander JM. An updated view of the intracellular mechanisms regulating cross-presentation. Front. Immunol. 4, 401 (2013).
    • (2013) Front. Immunol , vol.4 , pp. 401
    • Nair-Gupta, P.1    Blander, J.M.2
  • 14
    • 0015619335 scopus 로고
    • Identification of a novel cell type in peripheral lymphoid organs of mice. I. Morphology, quantitation, tissue distribution
    • Steinman RM, Cohn ZA. Identification of a novel cell type in peripheral lymphoid organs of mice. I. Morphology, quantitation, tissue distribution. J. Exp. Med. 137(5), 1142-1162 (1973).
    • (1973) J. Exp. Med , vol.137 , Issue.5 , pp. 1142-1162
    • Steinman, R.M.1    Cohn, Z.A.2
  • 15
    • 0028347936 scopus 로고
    • Murine dendritic cells pulsed in vitro with tumor antigen induce tumor resistance in vivo
    • Flamand V, Sornasse T, Thielemans K et al. Murine dendritic cells pulsed in vitro with tumor antigen induce tumor resistance in vivo. Eur. J. Immunol. 24(3), 605-610 (1994).
    • (1994) Eur. J. Immunol , vol.24 , Issue.3 , pp. 605-610
    • Flamand, V.1    Sornasse, T.2    Thielemans, K.3
  • 16
    • 0028811392 scopus 로고
    • Dendritic cells as carriers for a cytotoxic T-lymphocyte epitope-based peptide vaccine in protection against a human papillomavirus type 16-induced tumor
    • Ossevoort MA, Feltkamp MC, van Veen KJ, Melief CJ, Kast WM. Dendritic cells as carriers for a cytotoxic T-lymphocyte epitope-based peptide vaccine in protection against a human papillomavirus type 16-induced tumor. J. Immunother. Emphas. Tumor Immunol. 18(2), 86-94 (1995).
    • (1995) J. Immunother. Emphas. Tumor Immunol , vol.18 , Issue.2 , pp. 86-94
    • Ossevoort, M.A.1    Feltkamp, M.C.2    Van Veen, K.J.3    Melief, C.J.4    Kast, W.M.5
  • 17
    • 0028793675 scopus 로고
    • Bone marrow-derived dendritic cells pulsed with synthetic tumour peptides elicit protective and therapeutic antitumour immunity
    • Mayordomo JI, Zorina T, Storkus WJ et al. Bone marrow-derived dendritic cells pulsed with synthetic tumour peptides elicit protective and therapeutic antitumour immunity. Nat. Med. 1(12), 1297-1302 (1995).
    • (1995) Nat. Med , vol.1 , Issue.12 , pp. 1297-1302
    • Mayordomo, J.I.1    Zorina, T.2    Storkus, W.J.3
  • 18
    • 0030048724 scopus 로고    scopus 로고
    • Peptide-pulsed dendritic cells induce antigen-specific CTL-mediated protective tumor immunity
    • Celluzzi CM, Mayordomo JI, Storkus WJ, Lotze MT, Falo LD Jr. Peptide-pulsed dendritic cells induce antigen-specific CTL-mediated protective tumor immunity. J. Exp. Med. 183(1), 283-287 (1996).
    • (1996) J. Exp. Med , vol.183 , Issue.1 , pp. 283-287
    • Celluzzi, C.M.1    Mayordomo, J.I.2    Storkus, W.J.3    Lotze, M.T.4    Falo, L.D.5
  • 19
    • 0029744442 scopus 로고    scopus 로고
    • Vaccination with syngeneic, lymphoma-derived immunoglobulin idiotype combined with granulocyte/macrophage colony-stimulating factor primes mice for a protective T-cell response
    • Kwak LW, Young HA, Pennington RW, Weeks SD. Vaccination with syngeneic, lymphoma-derived immunoglobulin idiotype combined with granulocyte/macrophage colony-stimulating factor primes mice for a protective T-cell response. Proc. Natl Acad. Sci. USA 93(20), 10972-10977 (1996).
    • (1996) Proc. Natl Acad. Sci. USA , vol.93 , Issue.20 , pp. 10972-10977
    • Kwak, L.W.1    Young, H.A.2    Pennington, R.W.3    Weeks, S.D.4
  • 20
    • 0032828653 scopus 로고    scopus 로고
    • Complete molecular remissions induced by patient-specific vaccination plus granulocyte-monocyte colony-stimulating factor against lymphoma
    • Bendandi M, Gocke CD, Kobrin CB et al. Complete molecular remissions induced by patient-specific vaccination plus granulocyte-monocyte colony-stimulating factor against lymphoma. Nat. Med. 5(10), 1171-1177 (1999).
    • (1999) Nat. Med , vol.5 , Issue.10 , pp. 1171-1177
    • Bendandi, M.1    Gocke, C.D.2    Kobrin, C.B.3
  • 21
    • 0030026776 scopus 로고    scopus 로고
    • Vaccination of patients with B-cell lymphoma using autologous antigen-pulsed dendritic cells
    • Hsu FJ, Benike C, Fagnoni F et al. Vaccination of patients with B-cell lymphoma using autologous antigen-pulsed dendritic cells. Nat. Med. 2(1), 52-58 (1996).
    • (1996) Nat. Med , vol.2 , Issue.1 , pp. 52-58
    • Hsu, F.J.1    Benike, C.2    Fagnoni, F.3
  • 22
    • 0033120389 scopus 로고    scopus 로고
    • Idiotype vaccination using dendritic cells after autologous peripheral blood stem cell transplantation for multiple myeloma - A feasibility study
    • Reichardt VL, Okada CY, Liso A et al. Idiotype vaccination using dendritic cells after autologous peripheral blood stem cell transplantation for multiple myeloma - a feasibility study. Blood 93(7), 2411-2419 (1999).
    • (1999) Blood , vol.93 , Issue.7 , pp. 2411-2419
    • Reichardt, V.L.1    Okada, C.Y.2    Liso, A.3
  • 23
    • 0031941423 scopus 로고    scopus 로고
    • Vaccination of melanoma patients with peptide- or tumor lysate-pulsed dendritic cells
    • Nestle FO, Alijagic S, Gilliet M et al. Vaccination of melanoma patients with peptide- or tumor lysate-pulsed dendritic cells. Nat. Med. 4(3), 328-332 (1998).
    • (1998) Nat. Med , vol.4 , Issue.3 , pp. 328-332
    • Nestle, F.O.1    Alijagic, S.2    Gilliet, M.3
  • 24
    • 0033017065 scopus 로고    scopus 로고
    • A Phase i study of active immunotherapy with carcinoembryonic antigen peptide (CAP-1)-pulsed, autologous human cultured dendritic cells in patients with metastatic malignancies expressing carcinoembryonic antigen
    • Morse MA, Deng Y, Coleman D et al. A Phase I study of active immunotherapy with carcinoembryonic antigen peptide (CAP-1)-pulsed, autologous human cultured dendritic cells in patients with metastatic malignancies expressing carcinoembryonic antigen. Clin. Cancer Res. 5(6), 1331-1338 (1999).
    • (1999) Clin. Cancer Res , vol.5 , Issue.6 , pp. 1331-1338
    • Morse, M.A.1    Deng, Y.2    Coleman, D.3
  • 25
    • 78650359938 scopus 로고
    • Significance of increased phosphatase activity of bone at the site of osteoplastic metastases secondary to carcinoma of the prostate gland
    • Gutman EB, Sproul EE, Gutman AB. Significance of increased phosphatase activity of bone at the site of osteoplastic metastases secondary to carcinoma of the prostate gland. Am. J. Cancer 28(3), 485-495 (1936).
    • (1936) Am. J. Cancer , vol.28 , Issue.3 , pp. 485-495
    • Gutman, E.B.1    Sproul, E.E.2    Gutman, A.B.3
  • 26
    • 33646518377 scopus 로고    scopus 로고
    • Tissue-specificity of prostate specific antigens: Comparative analysis of transcript levels in prostate and non-prostatic tissues
    • Cunha AC, Weigle B, Kiessling A, Bachmann M, Rieber EP. Tissue-specificity of prostate specific antigens: comparative analysis of transcript levels in prostate and non-prostatic tissues. Cancer Lett. 236(2), 229-238 (2006).
    • (2006) Cancer Lett , vol.236 , Issue.2 , pp. 229-238
    • Cunha, A.C.1    Weigle, B.2    Kiessling, A.3    Bachmann, M.4    Rieber, E.P.5
  • 28
    • 2642640476 scopus 로고    scopus 로고
    • Induction of prostate tumor-specific CD8+ cytotoxic T-lymphocytes in vitro using antigen-presenting cells pulsed with prostatic acid phosphatase peptide
    • Peshwa MV, Shi JD, Ruegg C, Laus R, van Schooten WC. Induction of prostate tumor-specific CD8+ cytotoxic T-lymphocytes in vitro using antigen-presenting cells pulsed with prostatic acid phosphatase peptide. Prostate. 36(2), 129-138 (1998).
    • (1998) Prostate , vol.36 , Issue.2 , pp. 129-138
    • Peshwa, M.V.1    Shi, J.D.2    Ruegg, C.3    Laus, R.4    Van Schooten, W.C.5
  • 29
    • 0034554863 scopus 로고    scopus 로고
    • Immunotherapy of hormone-refractory prostate cancer with antigen-loaded dendritic cells
    • Small EJ, Fratesi P, Reese DM et al. Immunotherapy of hormone-refractory prostate cancer with antigen-loaded dendritic cells. J. Clin. Oncol. 18(23), 3894-3903 (2000).
    • (2000) J. Clin. Oncol , vol.18 , Issue.23 , pp. 3894-3903
    • Small, E.J.1    Fratesi, P.2    Reese, D.M.3
  • 30
    • 0020031143 scopus 로고
    • Human dendritic cells. Enrichment and characterization from peripheral blood
    • Van Voorhis W, Hair LS, Steinman RM, Kaplan G. Human dendritic cells. Enrichment and characterization from peripheral blood. J. Exp. Med. 155(4), 1172-1187 (1982).
    • (1982) J. Exp. Med , vol.155 , Issue.4 , pp. 1172-1187
    • Van Voorhis, W.1    Hair, L.S.2    Steinman, R.M.3    Kaplan, G.4
  • 31
    • 68549135290 scopus 로고    scopus 로고
    • Integrated data from 2 randomized, double-blind, placebo-controlled, Phase 3 trials of active cellular immunotherapy with sipuleucel-T in advanced prostate cancer
    • Higano CS, Schellhammer PF, Small EJ et al. Integrated data from 2 randomized, double-blind, placebo-controlled, Phase 3 trials of active cellular immunotherapy with sipuleucel-T in advanced prostate cancer. Cancer 115(16), 3670-3679 (2009).
    • (2009) Cancer , vol.115 , Issue.16 , pp. 3670-3679
    • Higano, C.S.1    Schellhammer, P.F.2    Small, E.J.3
  • 32
    • 33746012881 scopus 로고    scopus 로고
    • Placebo-controlled Phase III trial of immunologic therapy with sipuleucel-T (APC8015) in patients with metastatic, asymptomatic hormone refractory prostate cancer
    • Small EJ, Schellhammer PF, Higano CS et al. Placebo-controlled Phase III trial of immunologic therapy with sipuleucel-T (APC8015) in patients with metastatic, asymptomatic hormone refractory prostate cancer. J. Clin. Oncol. 24(19), 3089-3094 (2006).
    • (2006) J. Clin. Oncol , vol.24 , Issue.19 , pp. 3089-3094
    • Small, E.J.1    Schellhammer, P.F.2    Higano, C.S.3
  • 33
    • 77955066199 scopus 로고    scopus 로고
    • Sipuleucel-T immunotherapy for castration-resistant prostate cancer
    • Kantoff PW, Higano CS, Shore ND et al. Sipuleucel-T immunotherapy for castration-resistant prostate cancer. N. Engl. J. Med. 363(5), 411-422 (2010).
    • (2010) N. Engl. J. Med , vol.363 , Issue.5 , pp. 411-422
    • Kantoff, P.W.1    Higano, C.S.2    Shore, N.D.3
  • 34
    • 84961989851 scopus 로고    scopus 로고
    • Survival outcomes of sipuleucel-T Phase III studies: Impact of control-arm cross-over to salvage immunotherapy
    • George DJ, Nabhan C, DeVries T, Whitmore JB, Gomella LG. Survival outcomes of sipuleucel-T Phase III studies: impact of control-arm cross-over to salvage immunotherapy. Cancer Immunol. Res. 3(9), 1063-1069 (2015).
    • (2015) Cancer Immunol. Res , vol.3 , Issue.9 , pp. 1063-1069
    • George, D.J.1    Nabhan, C.2    DeVries, T.3    Whitmore, J.B.4    Gomella, L.G.5
  • 35
    • 84919662329 scopus 로고    scopus 로고
    • Activated lymphocyte recruitment into the tumor microenvironment following preoperative sipuleucel-T for localized prostate cancer
    • Fong L, Carroll P, Weinberg V et al. Activated lymphocyte recruitment into the tumor microenvironment following preoperative sipuleucel-T for localized prostate cancer. J. Natl Cancer Inst. 106(11), pii:dju268 (2014).
    • (2014) J. Natl Cancer Inst , vol.106 , Issue.11
    • Fong, L.1    Carroll, P.2    Weinberg, V.3
  • 36
    • 77954939175 scopus 로고    scopus 로고
    • Prostate cancer as a model for tumour immunotherapy
    • Drake CG. Prostate cancer as a model for tumour immunotherapy. Nat. Rev. 10(8), 580-593 (2010).
    • (2010) Nat. Rev , vol.10 , Issue.8 , pp. 580-593
    • Drake, C.G.1
  • 37
    • 22544458183 scopus 로고    scopus 로고
    • Antigen-presenting cells 8015 (Provenge) in patients with androgen-dependent, biochemically relapsed prostate cancer
    • Beinart G, Rini BI, Weinberg V, Small EJ. Antigen-presenting cells 8015 (Provenge) in patients with androgen-dependent, biochemically relapsed prostate cancer. Clin. Prostate Cancer 4(1), 55-60 (2005).
    • (2005) Clin. Prostate Cancer , vol.4 , Issue.1 , pp. 55-60
    • Beinart, G.1    Rini, B.I.2    Weinberg, V.3    Small, E.J.4
  • 38
    • 79960337024 scopus 로고    scopus 로고
    • Randomized trial of autologous cellular immunotherapy with sipuleucel-T in androgen-dependent prostate cancer
    • Beer TM, Bernstein GT, Corman JM et al. Randomized trial of autologous cellular immunotherapy with sipuleucel-T in androgen-dependent prostate cancer. Clin. Cancer Res. 17(13), 4558-4567 (2011).
    • (2011) Clin. Cancer Res , vol.17 , Issue.13 , pp. 4558-4567
    • Beer, T.M.1    Bernstein, G.T.2    Corman, J.M.3
  • 39
    • 85020442578 scopus 로고    scopus 로고
    • Sequencing of sipuleucel-T and androgen deprivation therapy in men with hormone-sensitive biochemically recurrent prostate cancer: A Phase II randomized trial
    • Antonarakis ES, Kibel AS, Yu EY et al. Sequencing of sipuleucel-T and androgen deprivation therapy in men with hormone-sensitive biochemically recurrent prostate cancer: a Phase II randomized trial. Clin. Cancer Res. 23(10), 2451-2459 (2017).
    • (2017) Clin. Cancer Res , vol.23 , Issue.10 , pp. 2451-2459
    • Antonarakis, E.S.1    Kibel, A.S.2    Yu, E.Y.3
  • 40
    • 84944937210 scopus 로고    scopus 로고
    • Nivolumab versus docetaxel in advanced nonsquamous non-small-cell lung cancer
    • Borghaei H, Paz-Ares L, Horn L et al. Nivolumab versus docetaxel in advanced nonsquamous non-small-cell lung cancer. N. Engl. J. Med. 373(17), 1627-1639 (2015).
    • (2015) N. Engl. J. Med , vol.373 , Issue.17 , pp. 1627-1639
    • Borghaei, H.1    Paz-Ares, L.2    Horn, L.3
  • 41
    • 77954801079 scopus 로고    scopus 로고
    • Improved survival with ipilimumab in patients with metastatic melanoma.N
    • Hodi FS, O'Day SJ, McDermott DF et al. Improved survival with ipilimumab in patients with metastatic melanoma.N. Engl. J. Med. 363(8), 711-723 (2010).
    • (2010) Engl. J. Med , vol.363 , Issue.8 , pp. 711-723
    • Hodi, F.S.1    O'Day, S.J.2    McDermott, D.F.3
  • 42
    • 73149092567 scopus 로고    scopus 로고
    • Guidelines for the evaluation of immune therapy activity in solid tumors: Immune-related response criteria
    • Wolchok JD, Hoos A, O'Day S et al. Guidelines for the evaluation of immune therapy activity in solid tumors: immune-related response criteria. Clin. Cancer Res. 15(23), 7412-7420 (2009).
    • (2009) Clin. Cancer Res , vol.15 , Issue.23 , pp. 7412-7420
    • Wolchok, J.D.1    Hoos, A.2    O'Day, S.3
  • 43
    • 77957787538 scopus 로고    scopus 로고
    • Therapeutic cancer vaccines in prostate cancer: The paradox of improved survival without changes in time to progression
    • Madan RA, Gulley JL, Fojo T, Dahut WL. Therapeutic cancer vaccines in prostate cancer: the paradox of improved survival without changes in time to progression. Oncologist 15(9), 969-975 (2010).
    • (2010) Oncologist , vol.15 , Issue.9 , pp. 969-975
    • Madan, R.A.1    Gulley, J.L.2    Fojo, T.3    Dahut, W.L.4
  • 44
    • 84872488155 scopus 로고    scopus 로고
    • Sipuleucel-T immune parameters correlate with survival: An analysis of the randomized Phase 3 clinical trials in men with castration-resistant prostate cancer
    • Sheikh NA, Petrylak D, Kantoff PW et al. Sipuleucel-T immune parameters correlate with survival: an analysis of the randomized Phase 3 clinical trials in men with castration-resistant prostate cancer. Cancer Immunol. Immunother. CII 62(1), 137-147 (2013).
    • (2013) Cancer Immunol. Immunother. CII , vol.62 , Issue.1 , pp. 137-147
    • Sheikh, N.A.1    Petrylak, D.2    Kantoff, P.W.3
  • 45
    • 84878601468 scopus 로고    scopus 로고
    • Lower baseline prostate-specific antigen is associated with a greater overall survival benefit from sipuleucel-T in the Immunotherapy for Prostate Adenocarcinoma Treatment (IMPACT) trial
    • Schellhammer PF, Chodak G, Whitmore JB, Sims R, Frohlich MW, Kantoff PW. Lower baseline prostate-specific antigen is associated with a greater overall survival benefit from sipuleucel-T in the Immunotherapy for Prostate Adenocarcinoma Treatment (IMPACT) trial. Urology 81(6), 1297-1302 (2013).
    • (2013) Urology , vol.81 , Issue.6 , pp. 1297-1302
    • Schellhammer, P.F.1    Chodak, G.2    Whitmore, J.B.3    Sims, R.4    Frohlich, M.W.5    Kantoff, P.W.6
  • 46
    • 84929361061 scopus 로고    scopus 로고
    • Humoral immune response against nontargeted tumor antigens after treatment with sipuleucel-T and its association with improved clinical outcome
    • GuhaThakurta D, Sheikh NA, Fan LQ et al. Humoral immune response against nontargeted tumor antigens after treatment with sipuleucel-T and its association with improved clinical outcome. Clin. Cancer Res. 21(16), 3619-3630 (2015).
    • (2015) Clin. Cancer Res , vol.21 , Issue.16 , pp. 3619-3630
    • GuhaThakurta, D.1    Sheikh, N.A.2    Fan, L.Q.3
  • 47
    • 84901819530 scopus 로고    scopus 로고
    • The potential role of antigen spread in immunotherapy for prostate cancer
    • Drake CG. The potential role of antigen spread in immunotherapy for prostate cancer. Clin. Adv. Hematol. Oncol. 12(5), 332-334 (2014).
    • (2014) Clin. Adv. Hematol. Oncol , vol.12 , Issue.5 , pp. 332-334
    • Drake, C.G.1
  • 49
    • 80051548463 scopus 로고    scopus 로고
    • Integrated safety data from 4 randomized, double-blind, controlled trials of autologous cellular immunotherapy with sipuleucel-T in patients with prostate cancer
    • Hall SJ, Klotz L, Pantuck AJ et al. Integrated safety data from 4 randomized, double-blind, controlled trials of autologous cellular immunotherapy with sipuleucel-T in patients with prostate cancer. J. Urol. 186(3), 877-881 (2011).
    • (2011) J. Urol , vol.186 , Issue.3 , pp. 877-881
    • Hall, S.J.1    Klotz, L.2    Pantuck, A.J.3
  • 51
    • 85009783306 scopus 로고    scopus 로고
    • Randomized, double-blind, Phase III trial of ipilimumab versus placebo in asymptomatic or minimally symptomatic patients with metastatic chemotherapy-naive castration-resistant prostate cancer
    • Beer TM, Kwon ED, Drake CG et al. Randomized, double-blind, Phase III trial of ipilimumab versus placebo in asymptomatic or minimally symptomatic patients with metastatic chemotherapy-naive castration-resistant prostate cancer. J. Clin. Oncol. 35(1), 40-47 (2017).
    • (2017) J. Clin. Oncol , vol.35 , Issue.1 , pp. 40-47
    • Beer, T.M.1    Kwon, E.D.2    Drake, C.G.3
  • 52
    • 84901641673 scopus 로고    scopus 로고
    • Ipilimumab versus placebo after radiotherapy in patients with metastatic castration-resistant prostate cancer that had progressed after docetaxel chemotherapy (CA184-043): A multicentre, randomised, double-blind, Phase 3 trial
    • Kwon ED, Drake CG, Scher HI et al. Ipilimumab versus placebo after radiotherapy in patients with metastatic castration-resistant prostate cancer that had progressed after docetaxel chemotherapy (CA184-043): a multicentre, randomised, double-blind, Phase 3 trial. Lancet Oncol. 15(7), 700-712 (2014).
    • (2014) Lancet Oncol , vol.15 , Issue.7 , pp. 700-712
    • Kwon, E.D.1    Drake, C.G.2    Scher, H.I.3
  • 53
    • 84862859820 scopus 로고    scopus 로고
    • Safety, activity, and immune correlates of anti-PD-1 antibody in cancer
    • Topalian SL, Hodi FS, Brahmer JR et al. Safety, activity, and immune correlates of anti-PD-1 antibody in cancer. N. Engl. J. Med. 366(26), 2443-2454 (2012).
    • (2012) N. Engl. J. Med , vol.366 , Issue.26 , pp. 2443-2454
    • Topalian, S.L.1    Hodi, F.S.2    Brahmer, J.R.3
  • 54
    • 84982267373 scopus 로고    scopus 로고
    • Early evidence of anti-PD-1 activity in enzalutamide-resistant prostate cancer
    • Graff JN, Alumkal JJ, Drake CG et al. Early evidence of anti-PD-1 activity in enzalutamide-resistant prostate cancer. Oncotarget 7(33), 52810-52817 (2016).
    • (2016) Oncotarget , vol.7 , Issue.33 , pp. 52810-52817
    • Graff, J.N.1    Alumkal, J.J.2    Drake, C.G.3
  • 55
    • 85034988275 scopus 로고    scopus 로고
    • Phase 2 biomarker-driven study of ipilimumab plus nivolumab (Ipi/Nivo) for ARV7-positive metastatic castrate-resistant prostate cancer (mCRPC)
    • Boudadi K, Suzman DL, Luber B et al. Phase 2 biomarker-driven study of ipilimumab plus nivolumab (Ipi/Nivo) for ARV7-positive metastatic castrate-resistant prostate cancer (mCRPC). J. Clin. Oncol. 35(15 Suppl.), 5035-5035 (2017).
    • (2017) J. Clin. Oncol , vol.35 , Issue.15 , pp. 5035
    • Boudadi, K.1    Suzman, D.L.2    Luber, B.3
  • 56
    • 85003819933 scopus 로고    scopus 로고
    • Mismatch repair deficiency may be common in ductal adenocarcinoma of the prostate
    • Schweizer MT, Cheng HH, Tretiakova MS et al. Mismatch repair deficiency may be common in ductal adenocarcinoma of the prostate. Oncotarget 7(50), 82504-82510 (2016).
    • (2016) Oncotarget , vol.7 , Issue.50 , pp. 82504-82510
    • Schweizer, M.T.1    Cheng, H.H.2    Tretiakova, M.S.3
  • 57
    • 84882837534 scopus 로고    scopus 로고
    • Signatures of mutational processes in human cancer
    • Alexandrov LB, Nik-Zainal S, Wedge DC et al. Signatures of mutational processes in human cancer. Nature 500(7463), 415-421 (2013).
    • (2013) Nature , vol.500 , Issue.7463 , pp. 415-421
    • Alexandrov, L.B.1    Nik-Zainal, S.2    Wedge, D.C.3
  • 58
    • 85026265866 scopus 로고    scopus 로고
    • Mismatch-repair deficiency predicts response of solid tumors to PD-1 blockade
    • Le DT, Durham JN, Smith KN et al. Mismatch-repair deficiency predicts response of solid tumors to PD-1 blockade. Science 357(6349), 409-413 (2017).
    • (2017) Science , vol.357 , Issue.6349 , pp. 409-413
    • Le, D.T.1    Durham, J.N.2    Smith, K.N.3
  • 60
    • 85016090030 scopus 로고    scopus 로고
    • VISTA is an inhibitory immune checkpoint that is increased after ipilimumab therapy in patients with prostate cancer
    • Gao J, Ward JF, Pettaway CA et al. VISTA is an inhibitory immune checkpoint that is increased after ipilimumab therapy in patients with prostate cancer. Nat. Med. 23(5), nm.4308 (2017).
    • (2017) Nat. Med , vol.23 , Issue.5 , pp. nm4308
    • Gao, J.1    Ward, J.F.2    Pettaway, C.A.3
  • 61
    • 33745304967 scopus 로고    scopus 로고
    • Combination immunotherapy with prostatic acid phosphatase pulsed antigen-presenting cells (provenge) plus bevacizumab in patients with serologic progression of prostate cancer after definitive local therapy
    • Rini BI, Weinberg V, Fong L, Conry S, Hershberg RM, Small EJ. Combination immunotherapy with prostatic acid phosphatase pulsed antigen-presenting cells (provenge) plus bevacizumab in patients with serologic progression of prostate cancer after definitive local therapy. Cancer 107(1), 67-74 (2006).
    • (2006) Cancer , vol.107 , Issue.1 , pp. 67-74
    • Rini, B.I.1    Weinberg, V.2    Fong, L.3    Conry, S.4    Hershberg, R.M.5    Small, E.J.6
  • 62
    • 84861690508 scopus 로고    scopus 로고
    • Randomized, double-blind, placebo-controlled Phase III trial comparing docetaxel and prednisone with or without bevacizumab in men with metastatic castration-resistant prostate cancer: CALGB 90401
    • Kelly WK, Halabi S, Carducci M et al. Randomized, double-blind, placebo-controlled Phase III trial comparing docetaxel and prednisone with or without bevacizumab in men with metastatic castration-resistant prostate cancer: CALGB 90401. J. Clin. Oncol. 30(13), 1534-1540 (2012).
    • (2012) J. Clin. Oncol , vol.30 , Issue.13 , pp. 1534-1540
    • Kelly, W.K.1    Halabi, S.2    Carducci, M.3
  • 63
    • 84942882550 scopus 로고    scopus 로고
    • A randomized Phase II trial of sipuleucel-T with concurrent versus sequential abiraterone acetate plus prednisone in metastatic castration-resistant prostate cancer
    • Small EJ, Lance RS, Gardner TA et al. A randomized Phase II trial of sipuleucel-T with concurrent versus sequential abiraterone acetate plus prednisone in metastatic castration-resistant prostate cancer. Clin. Cancer Res. 21(17), 3862-3869 (2015).
    • (2015) Clin. Cancer Res , vol.21 , Issue.17 , pp. 3862-3869
    • Small, E.J.1    Lance, R.S.2    Gardner, T.A.3
  • 64
    • 84919679854 scopus 로고    scopus 로고
    • A randomized Phase II, open-label study of sipuleucel-T with concurrent or sequential enzalutamide in metastatic castration-resistant prostate cancer (mCRPC)
    • Quinn DI, Petrylak DP, Pieczonka CM et al. A randomized Phase II, open-label study of sipuleucel-T with concurrent or sequential enzalutamide in metastatic castration-resistant prostate cancer (mCRPC). JCO 32(15), e16071-e16071 (2014).
    • (2014) JCO , vol.32 , Issue.15 , pp. e16071-e16071
    • Quinn, D.I.1    Petrylak, D.P.2    Pieczonka, C.M.3
  • 65
    • 84901587065 scopus 로고    scopus 로고
    • Food and Drug Administration. FDA approval for ipilimumab (2011). www.accessdata.fda.gov/drugsatfda docs/label/2011/125377s0000lbl.pdf
    • (2011) FDA Approval for Ipilimumab
  • 66
    • 85045445073 scopus 로고    scopus 로고
    • Phase i clinical trial of sipuleucel-T combined with escalating doses of ipilimumab in progressive metastatic castrate-resistant prostate cancer
    • Scholz M, Yep S, Chancey M et al. Phase I clinical trial of sipuleucel-T combined with escalating doses of ipilimumab in progressive metastatic castrate-resistant prostate cancer. ImmunoTargets Ther. 6, 11-16 (2017).
    • (2017) ImmunoTargets Ther , vol.6 , pp. 11-16
    • Scholz, M.1    Yep, S.2    Chancey, M.3
  • 67
    • 85045481861 scopus 로고    scopus 로고
    • European Medicines Agency. Provenge. Press Release (2013). www.ema.europa.eu/docs/en GB/document library/EPAR - Summary for the public/human/002513/WC500151157.pdf
    • (2013) Provenge. Press Release
  • 68
    • 85045436680 scopus 로고    scopus 로고
    • European Medicines Agency. Provenge (2015). www.ema.europa.eu/ema
    • (2015) Provenge
  • 69
    • 85045419222 scopus 로고    scopus 로고
    • Sanpower Group completes the acquisition of Dendreon from Valeant
    • Sanpower Group. Sanpower Group completes the acquisition of Dendreon from Valeant. PRNewswire (2017). www.prnewswire.com/news-releases/sanpower-group-completes-the-acquisition-of -dendreon-from-valeant-300481852.html
    • (2017) PRNewswire


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