Myocardial oxidative stress correlates with left ventricular dysfunction on strain echocardiography in a rodent model of sepsis

Intensive Care Medicine Experimental

Volumn 5, Issue 1, 2017, Pages

  Haileselassie, Bereketeab ^a,b   Su, Erik ^a   Pozios, Iraklis ^a   Niño, Diego F ^a   Liu, Hongyun ^a   Lu, Dai Yin ^a   Ventoulis, Ioannis ^a   Fulton, William B ^a   Sodhi, Chhinder P ^a   Hackam, David ^a   O’Rourke, Brian ^a   Abraham, Theodore ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Sepsis; Sepsis induced myocardial dysfunction; Shock; Ultrasound

Indexed keywords

CATALASE; INTERLEUKIN 1BETA; INTERLEUKIN 6; REACTIVE OXYGEN METABOLITE; SCAVENGER; TUMOR NECROSIS FACTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOMECHANICS; BLOOD FLOW VELOCITY; CARDIOMYOPATHY; CECAL LIGATION AND PUNCTURE-INDUCED SEPSIS; CIRCUMFERENTIAL STRAIN; CIRCUMFERENTIAL STRAIN RATE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DOWN REGULATION; ECHOCARDIOGRAPHY; ECHOGRAPHY; ENZYME INDUCTION; FLUORESCENCE MICROSCOPY; HEART EJECTION FRACTION; HEART FUNCTION; HEART LEFT VENTRICLE FAILURE; HEART RATE; IMMUNOHISTOCHEMISTRY; LONGITUDINAL STRAIN; MALE; MOUSE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; UPREGULATION;

EID: 85042935742     PISSN: None     EISSN: 2197425X     Source Type: Journal    
DOI: 10.1186/s40635-017-0134-5     Document Type: Article

References (38)

1. Martin GS, Mannino DM, Moss M (2006) The effect of age on the development and outcome of adult sepsis. Crit Care Med 34:15–21
2. Dombrovskiy VY, Martin AA, Sunderram J et al (2007) Rapid increase in hospitalization and mortality rates for severe sepsis in the United States: a trend analysis from 1993 to 2003. Crit Care Med 35:1244–1250
3. Court O, Kumar A, Parrillo JE et al (2002) Clinical review: myocardial depression in sepsis and septic shock. Crit Care 6:500–508
4. Sharma AC (2007) Sepsis-induced myocardial dysfunction. Shock 28:265–269
5. Prabhu MM, Yalakala SK, Shetty R et al (2015) Prognosis of left ventricular systolic dysfunction in septic shock patients. J Clin Diagn Res 9:OC05–08
6. Weng L, Liu YT, Du B et al (2012) The prognostic value of left ventricular systolic function measured by tissue Doppler imaging in septic shock. Crit Care 16:R71
7. Sevilla Berrios RA, O’Horo JC et al (2014) Correlation of left ventricular systolic dysfunction determined by low ejection fraction and 30-day mortality in patients with severe sepsis and septic shock: a systematic review and meta-analysis. J Crit Care 29:495–499
8. Munt B, Jue J, Gin K et al (1998) Diastolic filling in human severe sepsis: an echocardiographic study. Crit Care Med 26:1829–1833
9. Poelaert J, Declerck C, Vogelaers D et al (1997) Left ventricular systolic and diastolic function in septic shock. Intensive Care Med 23:553–560
10. Parker MM, Shelhamer JH, Bacharach SL et al (1984) Profound but reversible myocardial depression in patients with septic shock. Ann Intern Med 100:483–490
11. Langeland S, Wouters PF, Claus P et al (2006) Experimental assessment of a new research tool for the estimation of two-dimensional myocardial strain. Ultrasound Med Biol 32:1509–1513
12. Gjesdal O, Hopp E, Vartdal T et al (2007) Global longitudinal strain measured by two-dimensional speckle tracking echocardiography is closely related to myocardial infarct size in chronic ischaemic heart disease. Clin Sci (Lond) 113:287–296
13. Migrino RQ, Aggarwal D, Konorev E et al (2008) Early detection of doxorubicin cardiomyopathy using two-dimensional strain echocardiography. Ultrasound Med Biol 34:208–214
14. Shahul S, Rhee J, Hacker MR et al (2012) Subclinical left ventricular dysfunction in preeclamptic women with preserved left ventricular ejection fraction: a 2D speckle-tracking imaging study. Circ Cardiovasc Imaging 5:734–739
15. Rittirsch D, Huber-Lang MS, Flierl MA et al (2009) Immunodesign of experimental sepsis by cecal ligation and puncture. Nat Protoc 4:31–36
16. Kass DA, Hare JM, Georgakopoulos D et al (1998) Murine cardiac function: a cautionary tail. Circ Res 82:519–522
17. Stypmann J, Engelen MA, Troatz C et al (2009) Echocardiographic assessment of global left ventricular function in mice. Lab Anim 43:127–137
18. Burns AT, La Gerche A, D’Hooge J et al (2010) Left ventricular strain and strain rate: characterization of the effect of load in human subjects. Eur J Echocardiogr 11:283–289
19. Park YH, Kang SJ, Song JK et al (2008) Prognostic value of longitudinal strain after primary reperfusion therapy in patients with anterior-wall acute myocardial infarction. J Am Soc Echocardiogr 21:262–267
20. Tanaka H, Kawai H, Tatsumi K et al (2006) Improved regional myocardial diastolic function assessed by strain rate imaging in patients with coronary artery disease undergoing percutaneous coronary intervention. J Am Soc Echocardiogr 19:756–762
21. Orde SR, Pulido JN, Masaki M et al (2014) Outcome prediction in sepsis: speckle tracking echocardiography based assessment of myocardial function. Crit Care 18:R149
22. Dalla K, Hallman C, Bech-Hanssen O et al (2015) Strain echocardiography identifies impaired longitudinal systolic function in patients with septic shock and preserved ejection fraction. Cardiovasc Ultrasound 13:30
23. Parrillo JE, Burch C, Shelhamer JH et al (1985) A circulating myocardial depressant substance in humans with septic shock. Septic shock patients with a reduced ejection fraction have a circulating factor that depresses in vitro myocardial cell performance. J Clin Invest 76:1539–1553
24. Suliman HB, Carraway MS, Piantadosi CA et al (2003) Postlipopolysaccharide oxidative damage of mitochondrial DNA. Am J Respir Crit Care Med 167(4):570–579
25. Larche J, Lancel S, Hassoun SM et al (2006) Inhibition of mitochondrial permeability transition prevents sepsis-induced myocardial dysfunction and mortality. J Am Coll Cardiol 48(2):377–385
26. Carlson D, Maass DL, White DJ et al (2006) Antioxidant vitamin therapy alters sepsis-related apoptotic myocardial activity and inflammatory responses. Am J Phys Heart Circ Phys 291(6):H2779–H2789
27. Kuroda J, Ago T, Matsushima S, Zhai P, Schneider MD, Sadoshima J (2010) NADPH oxidase 4 (Nox4) is a major source of oxidative stress in the failing heart. Proc Natl Acad Sci 107(35):15565–15570
28. He L, Peng X, Zhu J, Chen X, Liu H, Tang C, Peng Y (2014) Mangiferin attenuate sepsis-induced acute kidney injury via antioxidant and anti-inflammatory effects. Am J Nephrol 40(5):441
29. Piel DA, Gruber PJ, Weinheimer CJ et al (2006) Mitochondrial resuscitation with exogenous cytochrome c in the septic heart. Crit Care Med 35(9):2120–2127
30. Dai DF, Chen T, Szeto H et al (2011) Mitochondrial targeted antioxidant peptide ameliorates hypertensive cardiomyopathy. J Am Coll Cardiol 58(1):73–82
31. Dai DF, Hsieh EJ, Liu Y et al (2012) Mitochondrial proteome remodeling in pressure overload-induced heart failure: the role of mitochondrial oxidative stress. Cardiovasc Res 93(1):79–88
32. Schriner SE, Linford NJ, Martin GM et al (2005) Extension of murine life span by overexpression of catalase targeted to mitochondria. Science 308(5730):1909–1911
33. Chang WT, Lee WH, Lee WT et al (2015) Left ventricular global longitudinal strain is independently associated with mortality in septic shock patients. Intensive Care Med 41:1791–1799
34. Hubbard WJ, Choudhry M, Schwacha MG et al (2005) Cecal ligation and puncture. Shock 24(Suppl 1):52–57
35. Bhan A et al (2014) High-frequency speckle tracking echocardiography in the assessment of left ventricular function and remodeling after murine myocardial infarction. Am J Phys Heart Circ Phys 306(9):H1371–H1383
36. Pritchard TJ, Kawase Y, Haghighi K, Anjak A, Cai W, Jiang M, Rubinstein J (2013) Active inhibitor-1 maintains protein hyper-phosphorylation in aging hearts and halts remodeling in failing hearts. PLoS One 8(12):e80717
37. Sørensen LL, Bedja D, Sysa-Shah P, Liu H, Maxwell A, Yi X, Gabrielson K (2016) Echocardiographic characterization of a murine model of hypertrophic obstructive cardiomyopathy induced by cardiac-specific overexpression of epidermal growth factor receptor 2. Comp Med 66(4):268–277
38. Swyers T, Redford D, Larson DF (2014) Volatile anesthetic-induced preconditioning. Perfusion 29:10–15