Impact of Boosted Antiretroviral Therapy on the Pharmacokinetics and Efficacy of Clopidogrel and Prasugrel Active Metabolites

Clinical Pharmacokinetics

Volumn 57, Issue 10, 2018, Pages 1347-1354

  Marsousi, Niloufar ^a,b   Daali, Youssef ^a,b,c   Fontana, Pierre ^a,d   Reny, Jean Luc ^a,d   Ancrenaz Sirot, Virginie ^a   Calmy, Alexandra ^a   Rudaz, Serge ^b,c   Desmeules, Jules Alexandre ^a,b,c,d   Samer, Caroline Flora ^a,c,d  

^a GENEVA UNIVERSITY HOSPITALS   (Switzerland)

^b UNIVERSITY OF LAUSANNE   (Switzerland)

^c Swiss Centre for Applied Human Toxicology   (Switzerland)

^d UNIVERSITY OF GENEVA   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

ABACAVIR; ATAZANAVIR; CLOPIDOGREL; COBICISTAT; DARUNAVIR; DRUG METABOLITE; EFAVIRENZ; ELVITEGRAVIR; EMTRICITABINE; LAMIVUDINE; NEVIRAPINE; PRASUGREL; RITONAVIR; TENOFOVIR; ANTIRETROVIRUS AGENT; P2RY12 PROTEIN, HUMAN; PURINERGIC P2Y RECEPTOR ANTAGONIST; PURINERGIC P2Y12 RECEPTOR;

ADULT; AGED; ANTICOAGULATION; ANTIRETROVIRAL THERAPY; AREA UNDER THE CURVE; ARTICLE; BLOOD SAMPLING; CLINICAL ARTICLE; CONTROLLED STUDY; CROSSOVER PROCEDURE; DRUG EFFICACY; DRUG TOLERABILITY; ELIMINATION HALF-LIFE; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTED PATIENT; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; LOADING DRUG DOSE; MALE; MAXIMUM PLASMA CONCENTRATION; PHARMACOKINETIC PARAMETERS; PLASMA CONCENTRATION-TIME CURVE; PLATELET REACTIVITY; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SINGLE DRUG DOSE; TIME TO MAXIMUM PLASMA CONCENTRATION; TREATMENT RESPONSE; UNSPECIFIED SIDE EFFECT; BLOOD; DRUG EFFECT; DRUG INTERACTION; METABOLISM; MIDDLE AGED; THROMBOCYTE;

ADULT; AGED; ANTI-RETROVIRAL AGENTS; AREA UNDER CURVE; BLOOD PLATELETS; CLOPIDOGREL; CROSS-OVER STUDIES; DRUG INTERACTIONS; HIV INFECTIONS; HUMANS; MALE; MIDDLE AGED; PRASUGREL HYDROCHLORIDE; PURINERGIC P2Y RECEPTOR ANTAGONISTS; RECEPTORS, PURINERGIC P2Y12;

EID: 85042104615     PISSN: 03125963     EISSN: 11791926     Source Type: Journal    
DOI: 10.1007/s40262-018-0637-6     Document Type: Article

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