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Volumn 90, Issue , 2018, Pages 76-83

Beyond thrombosis: Anti-β2GPI domain 1 antibodies identify late pregnancy morbidity in anti-phospholipid syndrome

(21)  Chighizola, Cecilia Beatrice a,b   Pregnolato, Francesca b   Andreoli, Laura c   Bodio, Caterina a,b   Cesana, Laura b   Comerio, Chiara d   Gerosa, Maria a,e   Grossi, Claudia b   Kumar, Rajesh c   Lazzaroni, Maria Grazia c   Mahler, Michael f   Mattia, Elena g   Nalli, Cecilia c   Norman, Gary L f   Raimondo, Maria Gabriella a,e   Ruffatti, Amelia g   Tonello, Marta g   Trespidi, Laura d   Tincani, Angela c   Borghi, Maria Orietta a,b   more..


Author keywords

Anti phospholipid antibodies; Anti phospholipid syndrome; Anti 2GPI domain 1 antibodies; Anti 2GPI domain 4 5 antibodies; Pregnancy morbidity

Indexed keywords

BETA2 GLYCOPROTEIN 1 ANTIBODY; BETA2 GLYCOPROTEIN DOMAIN 1 ANTIBODY; BETA2 GLYCOPROTEIN DOMAIN 4 ANTIBODY; BETA2 GLYCOPROTEIN DOMAIN 5 ANTIBODY; IMMUNOGLOBULIN G ANTIBODY; PHOSPHOLIPID ANTIBODY; UNCLASSIFIED DRUG; AUTOANTIBODY; BETA2 GLYCOPROTEIN 1;

EID: 85041900351     PISSN: 08968411     EISSN: 10959157     Source Type: Journal    
DOI: 10.1016/j.jaut.2018.02.002     Document Type: Article
Times cited : (58)

References (43)
  • 1
    • 33344458573 scopus 로고    scopus 로고
    • International consensus statement on an update of the classification criteria for definite antiphospholipid syndrome (APS)
    • Miyakis, S., Lockshin, M.D., Atsumi, T., Branch, D.W., Brey, R.L., Cervera, R., et al. International consensus statement on an update of the classification criteria for definite antiphospholipid syndrome (APS). J. Thromb. Haemostasis 4 (2006), 295–306.
    • (2006) J. Thromb. Haemostasis , vol.4 , pp. 295-306
    • Miyakis, S.1    Lockshin, M.D.2    Atsumi, T.3    Branch, D.W.4    Brey, R.L.5    Cervera, R.6
  • 2
    • 79958086576 scopus 로고    scopus 로고
    • Pathogenesis of antiphospholipid syndrome: understanding the antibodies
    • Meroni, P.L., Borghi, M.O., Raschi, E., Tedesco, F., Pathogenesis of antiphospholipid syndrome: understanding the antibodies. Nat. Rev. Rheumatol. 7 (2011), 330–339.
    • (2011) Nat. Rev. Rheumatol. , vol.7 , pp. 330-339
    • Meroni, P.L.1    Borghi, M.O.2    Raschi, E.3    Tedesco, F.4
  • 3
    • 0042832999 scopus 로고    scopus 로고
    • Prevalence and clinical correlations of antibodies against six beta2-glycoprotein-I-related peptides in the antiphospholipid syndrome
    • Shoenfeld, Y., Krause, I., Kvapil, F., Sulkes, J., Lev, S., von Landenberg, P., et al. Prevalence and clinical correlations of antibodies against six beta2-glycoprotein-I-related peptides in the antiphospholipid syndrome. J. Clin. Immunol. 23 (2003), 377–383.
    • (2003) J. Clin. Immunol. , vol.23 , pp. 377-383
    • Shoenfeld, Y.1    Krause, I.2    Kvapil, F.3    Sulkes, J.4    Lev, S.5    von Landenberg, P.6
  • 4
    • 84896702818 scopus 로고    scopus 로고
    • New tests to detect Antiphospholipid antibodies: anti-domain I beta-2-glycoprotein-I antibodies
    • Chighizola, C.B., Gerosa, M., Meroni, P.L., New tests to detect Antiphospholipid antibodies: anti-domain I beta-2-glycoprotein-I antibodies. Curr. Rheumatol. Rep., 16, 2014, 402.
    • (2014) Curr. Rheumatol. Rep. , vol.16 , pp. 402
    • Chighizola, C.B.1    Gerosa, M.2    Meroni, P.L.3
  • 5
    • 0032217240 scopus 로고    scopus 로고
    • Anti-beta2 glycoprotein I (beta2GPI) autoantibodies recognize an epitope on the first domain of beta2GPI
    • Iverson, G.M., Victoria, E.J., Marquis, D.M., Anti-beta2 glycoprotein I (beta2GPI) autoantibodies recognize an epitope on the first domain of beta2GPI. Proc. Natl. Acad. Sci. U.S.A. 95 (1998), 15542–15546.
    • (1998) Proc. Natl. Acad. Sci. U.S.A. , vol.95 , pp. 15542-15546
    • Iverson, G.M.1    Victoria, E.J.2    Marquis, D.M.3
  • 6
    • 0034742562 scopus 로고    scopus 로고
    • Beta2-glycoprotein I-dependent anticardiolipin antibodies preferentially bind the amino terminal domain of beta2-glycoprotein I
    • McNeeley, P.A., Dlott, J.S., Furie, R.A., Jack, R.M., Ortel, T.L., Triplett, D.A., et al. Beta2-glycoprotein I-dependent anticardiolipin antibodies preferentially bind the amino terminal domain of beta2-glycoprotein I. Thromb. Haemostasis 86 (2001), 590–595.
    • (2001) Thromb. Haemostasis , vol.86 , pp. 590-595
    • McNeeley, P.A.1    Dlott, J.S.2    Furie, R.A.3    Jack, R.M.4    Ortel, T.L.5    Triplett, D.A.6
  • 7
    • 0033830410 scopus 로고    scopus 로고
    • Epitope studies with anti-beta 2-glycoprotein I antibodies from autoantibody and immunized sources
    • Reddel, S.W., Wang, Y.X., Sheng, Y.H., Krilis, S.A., Epitope studies with anti-beta 2-glycoprotein I antibodies from autoantibody and immunized sources. J. Autoimmun. 15 (2000), 91–96.
    • (2000) J. Autoimmun. , vol.15 , pp. 91-96
    • Reddel, S.W.1    Wang, Y.X.2    Sheng, Y.H.3    Krilis, S.A.4
  • 8
    • 82455198748 scopus 로고    scopus 로고
    • Immune responses against domain I of β(2)-glycoprotein I are driven by conformational changes: domain I of β(2)-glycoprotein I harbors a cryptic immunogenic epitope
    • de Laat, B., van Berkel, M., Urbanus, R.T., Siregar, B., de Groot, P.G., Gebbink, M.F., et al. Immune responses against domain I of β(2)-glycoprotein I are driven by conformational changes: domain I of β(2)-glycoprotein I harbors a cryptic immunogenic epitope. Arthritis Rheum. 63 (2011), 3960–3968.
    • (2011) Arthritis Rheum. , vol.63 , pp. 3960-3968
    • de Laat, B.1    van Berkel, M.2    Urbanus, R.T.3    Siregar, B.4    de Groot, P.G.5    Gebbink, M.F.6
  • 9
    • 33846236309 scopus 로고    scopus 로고
    • Binding of antiphospholipid antibodies to discontinuous epitopes on domain I of human beta(2)-glycoprotein I: mutation studies including residues R39 to R43
    • Ioannou, Y., Pericleous, C., Giles, I., Latchman, D.S., Isenberg, D.A., Rahman, A., Binding of antiphospholipid antibodies to discontinuous epitopes on domain I of human beta(2)-glycoprotein I: mutation studies including residues R39 to R43. Arthritis Rheum. 56 (2007), 280–290.
    • (2007) Arthritis Rheum. , vol.56 , pp. 280-290
    • Ioannou, Y.1    Pericleous, C.2    Giles, I.3    Latchman, D.S.4    Isenberg, D.A.5    Rahman, A.6
  • 10
    • 80055066032 scopus 로고    scopus 로고
    • Incidence of a first thromboembolic event in asymptomatic carriers of high-risk antiphospholipid antibody profile: a multicenter prospective study
    • Pengo, V., Ruffatti, A., Legnani, C., Testa, S., Fierro, T., Marongiu, F., et al. Incidence of a first thromboembolic event in asymptomatic carriers of high-risk antiphospholipid antibody profile: a multicenter prospective study. Blood 118 (2011), 4714–4718.
    • (2011) Blood , vol.118 , pp. 4714-4718
    • Pengo, V.1    Ruffatti, A.2    Legnani, C.3    Testa, S.4    Fierro, T.5    Marongiu, F.6
  • 11
    • 84938099968 scopus 로고    scopus 로고
    • Clinical characterization of antiphospholipid syndrome by detection of IgG antibodies against β2 -glycoprotein i domain 1 and domain 4/5: ratio of anti-domain 1 to anti-domain 4/5 as a useful new biomarker for antiphospholipid syndrome
    • Andreoli, L., Chighizola, C.B., Nalli, C., Gerosa, M., Borghi, M.O., Pregnolato, F., et al. Clinical characterization of antiphospholipid syndrome by detection of IgG antibodies against β2 -glycoprotein i domain 1 and domain 4/5: ratio of anti-domain 1 to anti-domain 4/5 as a useful new biomarker for antiphospholipid syndrome. Arthritis Rheum. 67 (2015), 2196–2204.
    • (2015) Arthritis Rheum. , vol.67 , pp. 2196-2204
    • Andreoli, L.1    Chighizola, C.B.2    Nalli, C.3    Gerosa, M.4    Borghi, M.O.5    Pregnolato, F.6
  • 12
    • 82355182716 scopus 로고    scopus 로고
    • Antibodies to domain I of β(2)Glycoprotein I are in close relation to patients risk categories in antiphospholipid syndrome (APS)
    • Banzato, A., Pozzi, N., Frasson, R., De Filippis, V., Ruffatti, A., Bison, E., et al. Antibodies to domain I of β(2)Glycoprotein I are in close relation to patients risk categories in antiphospholipid syndrome (APS). Thromb. Res. 128 (2011), 583–586.
    • (2011) Thromb. Res. , vol.128 , pp. 583-586
    • Banzato, A.1    Pozzi, N.2    Frasson, R.3    De Filippis, V.4    Ruffatti, A.5    Bison, E.6
  • 13
    • 84973333101 scopus 로고    scopus 로고
    • Anti-beta-2 glycoprotein I epitope specificity: from experimental models to diagnostic tools
    • Meroni, P.L., Anti-beta-2 glycoprotein I epitope specificity: from experimental models to diagnostic tools. Lupus 25 (2016), 905–910.
    • (2016) Lupus , vol.25 , pp. 905-910
    • Meroni, P.L.1
  • 14
    • 65349188214 scopus 로고    scopus 로고
    • In vivo inhibition of antiphospholipid antibody-induced pathogenicity utilizing the antigenic target peptide domain I of beta2-glycoprotein I: proof of concept
    • Ioannou, Y., Romay-Penabad, Z., Pericleous, C., Giles, I., Papalardo, E., Vargas, G., et al. In vivo inhibition of antiphospholipid antibody-induced pathogenicity utilizing the antigenic target peptide domain I of beta2-glycoprotein I: proof of concept. J. Thromb. Haemostasis 7 (2009), 833–842.
    • (2009) J. Thromb. Haemostasis , vol.7 , pp. 833-842
    • Ioannou, Y.1    Romay-Penabad, Z.2    Pericleous, C.3    Giles, I.4    Papalardo, E.5    Vargas, G.6
  • 15
    • 84901705578 scopus 로고    scopus 로고
    • A non complement-fixing antibody to β2 glycoprotein I as a novel therapy to control abortions and thrombosis in antiphospholipid syndrome
    • Agostinis, C., Durigutto, P., Sblattero, D., Borghi, M.O., Grossi, C., Guida, F., et al. A non complement-fixing antibody to β2 glycoprotein I as a novel therapy to control abortions and thrombosis in antiphospholipid syndrome. Blood 123 (2014), 3478–3487.
    • (2014) Blood , vol.123 , pp. 3478-3487
    • Agostinis, C.1    Durigutto, P.2    Sblattero, D.3    Borghi, M.O.4    Grossi, C.5    Guida, F.6
  • 16
    • 84988483807 scopus 로고    scopus 로고
    • Role of anti-domain 1-β2 glycoprotein I antibodies in the diagnosis and risk stratification of antiphospholipid syndrome
    • De Craemer, A.S., Musial, J., Devreese, K.M., Role of anti-domain 1-β2 glycoprotein I antibodies in the diagnosis and risk stratification of antiphospholipid syndrome. J. Thromb. Haemostasis 14 (2016), 1779–1787.
    • (2016) J. Thromb. Haemostasis , vol.14 , pp. 1779-1787
    • De Craemer, A.S.1    Musial, J.2    Devreese, K.M.3
  • 17
    • 84992359635 scopus 로고    scopus 로고
    • Role of anti-domain 1- β(2) glycoprotein I antibodies in the diagnosis and risk stratification of antiphospholipid syndrome: comment
    • Zhang, S., Wu, Z., Zhang, F., Li, Y., Role of anti-domain 1- β(2) glycoprotein I antibodies in the diagnosis and risk stratification of antiphospholipid syndrome: comment. J. Thromb. Haemostasis 14 (2016), 2076–2078.
    • (2016) J. Thromb. Haemostasis , vol.14 , pp. 2076-2078
    • Zhang, S.1    Wu, Z.2    Zhang, F.3    Li, Y.4
  • 18
    • 84973358481 scopus 로고    scopus 로고
    • Autoantibodies to domain 1 of beta 2 glycoprotein I determined using a novel chemiluminescence immunoassay demonstrate association with thrombosis in patients with antiphospholipid syndrome
    • Mahler, M., Albesa, R., Zohoury, N., Bertolaccini, M.L., Ateka-Barrutia, O., Rodriguez-Garcia, J.L., et al. Autoantibodies to domain 1 of beta 2 glycoprotein I determined using a novel chemiluminescence immunoassay demonstrate association with thrombosis in patients with antiphospholipid syndrome. Lupus 25 (2016), 911–916.
    • (2016) Lupus , vol.25 , pp. 911-916
    • Mahler, M.1    Albesa, R.2    Zohoury, N.3    Bertolaccini, M.L.4    Ateka-Barrutia, O.5    Rodriguez-Garcia, J.L.6
  • 19
    • 84928773743 scopus 로고    scopus 로고
    • Antiphospholipid syndrome: antibodies to domain 1 of β2-glycoprotein 1 correctly classify patients at risk
    • Pengo, V., Ruffatti, A., Tonello, M., Cuffaro, S., Banzato, A., Bison, E., et al. Antiphospholipid syndrome: antibodies to domain 1 of β2-glycoprotein 1 correctly classify patients at risk. J. Thromb. Haemostasis 13 (2015), 782–787.
    • (2015) J. Thromb. Haemostasis , vol.13 , pp. 782-787
    • Pengo, V.1    Ruffatti, A.2    Tonello, M.3    Cuffaro, S.4    Banzato, A.5    Bison, E.6
  • 20
    • 13544276197 scopus 로고    scopus 로고
    • IgG antibodies that recognize epitope Gly40-Arg43 in domain I of beta 2-glycoprotein I cause LAC, and their presence correlates strongly with thrombosis
    • de Laat, B., Derksen, R.H., Urbanus, R.T., de Groot, P.G., IgG antibodies that recognize epitope Gly40-Arg43 in domain I of beta 2-glycoprotein I cause LAC, and their presence correlates strongly with thrombosis. Blood 105 (2005), 1540–1545.
    • (2005) Blood , vol.105 , pp. 1540-1545
    • de Laat, B.1    Derksen, R.H.2    Urbanus, R.T.3    de Groot, P.G.4
  • 21
    • 85026999474 scopus 로고    scopus 로고
    • Prevalence and thrombotic risk assessment of anti-domain I beta 2 glycoprotein I antibodies: a systematic review
    • Radin, M., Cecchi, I., Roccatello, D., Meroni, P.L., Sciascia, S., Prevalence and thrombotic risk assessment of anti-domain I beta 2 glycoprotein I antibodies: a systematic review. Sem. Thromb. Haemost, 2017, 10.1055/s-0037-1603936.
    • (2017) Sem. Thromb. Haemost
    • Radin, M.1    Cecchi, I.2    Roccatello, D.3    Meroni, P.L.4    Sciascia, S.5
  • 22
    • 84929000742 scopus 로고    scopus 로고
    • Detection of IgG anti-domain I beta2 glycoprotein I antibodies by chemiluminescence immunoassay in primary antiphospholipid syndrome
    • Meneghel, L., Ruffatti, A., Gavasso, S., Tonello, M., Mattia, E., Spiezia, L., et al. Detection of IgG anti-domain I beta2 glycoprotein I antibodies by chemiluminescence immunoassay in primary antiphospholipid syndrome. Clin. Chim. Acta 446 (2015), 201–205.
    • (2015) Clin. Chim. Acta , vol.446 , pp. 201-205
    • Meneghel, L.1    Ruffatti, A.2    Gavasso, S.3    Tonello, M.4    Mattia, E.5    Spiezia, L.6
  • 23
    • 70449390005 scopus 로고    scopus 로고
    • The association between circulating antibodies against domain I of beta2-glycoprotein I and thrombosis: an international multicenter study
    • de Laat, B., Pengo, V., Pabinger, I., Musial, J., Voskuyl, A.E., Bultink, I.E., et al. The association between circulating antibodies against domain I of beta2-glycoprotein I and thrombosis: an international multicenter study. J. Thromb. Haemostasis 7 (2009), 1767–1773.
    • (2009) J. Thromb. Haemostasis , vol.7 , pp. 1767-1773
    • de Laat, B.1    Pengo, V.2    Pabinger, I.3    Musial, J.4    Voskuyl, A.E.5    Bultink, I.E.6
  • 25
    • 84973661586 scopus 로고    scopus 로고
    • Measuring IgA anti-β2-glycoprotein I and IgG/IgA anti-domain I antibodies adds value to current serological assays for the antiphospholipid syndrome
    • Pericleous, C., Ferreira, I., Borghi, O., Pregnolato, F., McDonnell, T., Garza-Garcia, A., et al. Measuring IgA anti-β2-glycoprotein I and IgG/IgA anti-domain I antibodies adds value to current serological assays for the antiphospholipid syndrome. PLoS One, 11, 2016, e0156407, 10.1371/journal.pone.0156407.
    • (2016) PLoS One , vol.11
    • Pericleous, C.1    Ferreira, I.2    Borghi, O.3    Pregnolato, F.4    McDonnell, T.5    Garza-Garcia, A.6
  • 26
    • 78751704220 scopus 로고    scopus 로고
    • Anti-β₂-glycoprotein I IgG antibodies from 1-year-old healthy children born to mothers with systemic autoimmune diseases preferentially target domain 4/5: might it be the reason for their ‘innocent’ profile?
    • Andreoli, L., Nalli, C., Motta, M., Norman, G.L., Shums, Z., Encabo, S., et al. Anti-β₂-glycoprotein I IgG antibodies from 1-year-old healthy children born to mothers with systemic autoimmune diseases preferentially target domain 4/5: might it be the reason for their ‘innocent’ profile?. Ann. Rheum. Dis. 70 (2011), 380–383.
    • (2011) Ann. Rheum. Dis. , vol.70 , pp. 380-383
    • Andreoli, L.1    Nalli, C.2    Motta, M.3    Norman, G.L.4    Shums, Z.5    Encabo, S.6
  • 27
    • 33846685872 scopus 로고    scopus 로고
    • Patients with atherosclerotic syndrome, negative in anti-cardiolipin assays, make IgA autoantibodies that preferentially target domain 4 of beta2-GPI
    • Iverson, G.M., von Mühlen, C.A., Staub, H.L., Lassen, A.J., Binder, W., Norman, G.L., Patients with atherosclerotic syndrome, negative in anti-cardiolipin assays, make IgA autoantibodies that preferentially target domain 4 of beta2-GPI. J. Autoimmun. 27 (2006), 266–271.
    • (2006) J. Autoimmun. , vol.27 , pp. 266-271
    • Iverson, G.M.1    von Mühlen, C.A.2    Staub, H.L.3    Lassen, A.J.4    Binder, W.5    Norman, G.L.6
  • 28
    • 0036218138 scopus 로고    scopus 로고
    • Distinguishing features of anti-beta2 glycoprotein I antibodies between patients with leprosy and the antiphospholipid syndrome
    • Arvieux, J., Renaudineau, Y., Mane, I., Perraut, R., Krilis, S.A., Youinou, P., Distinguishing features of anti-beta2 glycoprotein I antibodies between patients with leprosy and the antiphospholipid syndrome. Thromb. Haemostasis 87 (2002), 599–605.
    • (2002) Thromb. Haemostasis , vol.87 , pp. 599-605
    • Arvieux, J.1    Renaudineau, Y.2    Mane, I.3    Perraut, R.4    Krilis, S.A.5    Youinou, P.6
  • 29
    • 0036315878 scopus 로고    scopus 로고
    • Anti-beta(2)-glycoprotein I antibodies in children with atopic dermatitis
    • Ambrozic, A., Avcin, T., Ichikawa, K., Kveder, T., Matsuura, E., Hojnik, M., et al. Anti-beta(2)-glycoprotein I antibodies in children with atopic dermatitis. Int. Immunol. 14 (2002), 823–830.
    • (2002) Int. Immunol. , vol.14 , pp. 823-830
    • Ambrozic, A.1    Avcin, T.2    Ichikawa, K.3    Kveder, T.4    Matsuura, E.5    Hojnik, M.6
  • 30
    • 84931566678 scopus 로고    scopus 로고
    • Antibodies to domain 4/5 (Dm4/5) of β2-glycoprotein 1 (β2GP1) in different antiphospholipid (aPL) antibody profiles
    • Pengo, V., Ruffatti, A., Tonello, M., Hoxha, A., Bison, E., Denas, G., et al. Antibodies to domain 4/5 (Dm4/5) of β2-glycoprotein 1 (β2GP1) in different antiphospholipid (aPL) antibody profiles. Thromb. Res. 136 (2015), 161–163.
    • (2015) Thromb. Res. , vol.136 , pp. 161-163
    • Pengo, V.1    Ruffatti, A.2    Tonello, M.3    Hoxha, A.4    Bison, E.5    Denas, G.6
  • 31
    • 70350004861 scopus 로고    scopus 로고
    • Update of the guidelines for lupus anticoagulant detection. Subcommittee on lupus anticoagulant/antiphospholipid antibody of the scientific and standardisation committee of the international society on thrombosis and haemostasis
    • Pengo, V., Tripodi, A., Reber, G., Rand, J.H., Ortel, T.L., Galli, M., et al. Update of the guidelines for lupus anticoagulant detection. Subcommittee on lupus anticoagulant/antiphospholipid antibody of the scientific and standardisation committee of the international society on thrombosis and haemostasis. J. Thromb. Haemostasis 7 (2009), 1737–1740.
    • (2009) J. Thromb. Haemostasis , vol.7 , pp. 1737-1740
    • Pengo, V.1    Tripodi, A.2    Reber, G.3    Rand, J.H.4    Ortel, T.L.5    Galli, M.6
  • 32
    • 7044260448 scopus 로고    scopus 로고
    • Minimal requirements for antiphospholipid antibodies ELISAs proposed by the European Forum on antiphospholipid antibodies
    • Tincani, A., Allegri, F., Balestrieri, G., Reber, G., Sanmarco, M., Meroni, P., et al. Minimal requirements for antiphospholipid antibodies ELISAs proposed by the European Forum on antiphospholipid antibodies. Thromb. Res. 114 (2004), 553–558.
    • (2004) Thromb. Res. , vol.114 , pp. 553-558
    • Tincani, A.1    Allegri, F.2    Balestrieri, G.3    Reber, G.4    Sanmarco, M.5    Meroni, P.6
  • 33
    • 82955173886 scopus 로고    scopus 로고
    • Standards and reference materials for the anticardiolipin and anti-β2glycoprotein I assays: a report of recommendations from the APL Task Force at the 13th International Congress on Antiphospholipid Antibodies
    • Pierangeli, S.S., Favaloro, E.J., Lakos, G., et al. Standards and reference materials for the anticardiolipin and anti-β2glycoprotein I assays: a report of recommendations from the APL Task Force at the 13th International Congress on Antiphospholipid Antibodies. Clin. Chim. Acta 413 (2012), 358–360.
    • (2012) Clin. Chim. Acta , vol.413 , pp. 358-360
    • Pierangeli, S.S.1    Favaloro, E.J.2    Lakos, G.3
  • 34
    • 0037373575 scopus 로고    scopus 로고
    • Confounding and confounders
    • McNamee, R., Confounding and confounders. Occup. Environ. Med. 60 (2003), 227–234.
    • (2003) Occup. Environ. Med. , vol.60 , pp. 227-234
    • McNamee, R.1
  • 35
    • 84876908622 scopus 로고
    • Generalized collinearity diagnostics
    • Fox, J., Monette, G., Generalized collinearity diagnostics. JASA 87 (1992), 178–183.
    • (1992) JASA , vol.87 , pp. 178-183
    • Fox, J.1    Monette, G.2
  • 36
    • 0013438297 scopus 로고
    • The Linear Regression Model under Test
    • Physica-Verlag Heidelberg, Germany
    • Krämer, W., Sonnberger, H., The Linear Regression Model under Test. 1986, Physica-Verlag, Heidelberg, Germany.
    • (1986)
    • Krämer, W.1    Sonnberger, H.2
  • 37
    • 0030761057 scopus 로고    scopus 로고
    • Placental pathology and antiphospholipid antibodies: a descriptive study
    • Salafia, C.M., Cowchock, F.S., Placental pathology and antiphospholipid antibodies: a descriptive study. Am. J. Perinatol. 14 (1997), 435–441.
    • (1997) Am. J. Perinatol. , vol.14 , pp. 435-441
    • Salafia, C.M.1    Cowchock, F.S.2
  • 38
    • 0036117498 scopus 로고    scopus 로고
    • Defective endovascular trophoblast invasion in primary antiphospholipid antibody syndrome-associated early pregnancy failure
    • Sebire, N.J., Fox, H., Backos, M., Rai, R., Paterson, C., Regan, L., Defective endovascular trophoblast invasion in primary antiphospholipid antibody syndrome-associated early pregnancy failure. Hum. Reprod. 17 (2002), 1067–1071.
    • (2002) Hum. Reprod. , vol.17 , pp. 1067-1071
    • Sebire, N.J.1    Fox, H.2    Backos, M.3    Rai, R.4    Paterson, C.5    Regan, L.6
  • 39
    • 84925202181 scopus 로고    scopus 로고
    • Histopathology in the placentae of women with antiphospholipid antibodies: a systematic review of the literature
    • Viall, C.A., Chamley, L.W., Histopathology in the placentae of women with antiphospholipid antibodies: a systematic review of the literature. Autoimmun. Rev. 14 (2015), 446–471.
    • (2015) Autoimmun. Rev. , vol.14 , pp. 446-471
    • Viall, C.A.1    Chamley, L.W.2
  • 40
    • 84911468310 scopus 로고    scopus 로고
    • Update on the current recommendations and outcomes in pregnant women with antiphospholipid syndrome
    • Chighizola, C.B., Gerosa, M., Trespidi, L., Di Giacomo, A., Rossi, F., Acaia, B., et al. Update on the current recommendations and outcomes in pregnant women with antiphospholipid syndrome. Expet Rev. Clin. Immunol. 10 (2014), 1505–1517.
    • (2014) Expet Rev. Clin. Immunol. , vol.10 , pp. 1505-1517
    • Chighizola, C.B.1    Gerosa, M.2    Trespidi, L.3    Di Giacomo, A.4    Rossi, F.5    Acaia, B.6
  • 41
    • 84893089265 scopus 로고    scopus 로고
    • Comparative incidence of pregnancy outcomes in treated obstetric antiphospholipid syndrome: the NOH-APS observational study
    • Bouvier, S., Cochery-Nouvellon, E., Lavigne-Lissalde, G., Mercier, E., Marchetti, T., Balducchi, J.P., et al. Comparative incidence of pregnancy outcomes in treated obstetric antiphospholipid syndrome: the NOH-APS observational study. Blood 123 (2014), 404–413.
    • (2014) Blood , vol.123 , pp. 404-413
    • Bouvier, S.1    Cochery-Nouvellon, E.2    Lavigne-Lissalde, G.3    Mercier, E.4    Marchetti, T.5    Balducchi, J.P.6
  • 42
    • 84908528863 scopus 로고    scopus 로고
    • Treatment strategies and pregnancy outcomes in antiphospholipid syndrome patients with thrombosis and triple antiphospholipid positivity. A European multicentre retrospective study
    • Ruffatti, A., Salvan, E., Del Ross, T., Gerosa, M., Andreoli, L., Maina, A., et al. Treatment strategies and pregnancy outcomes in antiphospholipid syndrome patients with thrombosis and triple antiphospholipid positivity. A European multicentre retrospective study. Thromb. Haemostasis 112 (2014), 727–735.
    • (2014) Thromb. Haemostasis , vol.112 , pp. 727-735
    • Ruffatti, A.1    Salvan, E.2    Del Ross, T.3    Gerosa, M.4    Andreoli, L.5    Maina, A.6
  • 43
    • 85053223587 scopus 로고    scopus 로고
    • Antiphospholipid syndrome alliance for clinical trials and international networking (APS ACTION) core laboratory validation exercise: comparison of enzyme-linked immunosorbant assay (ELISA) and chemiluminescence immunoassay (CIA)
    • Bertolaccini, M.L., Andrade, D., Lakos, G., Willis, R., Pengo, V., Banzato, A., et al. Antiphospholipid syndrome alliance for clinical trials and international networking (APS ACTION) core laboratory validation exercise: comparison of enzyme-linked immunosorbant assay (ELISA) and chemiluminescence immunoassay (CIA). Arthritis Rheum., 67, 2015.
    • (2015) Arthritis Rheum. , vol.67
    • Bertolaccini, M.L.1    Andrade, D.2    Lakos, G.3    Willis, R.4    Pengo, V.5    Banzato, A.6


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