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Volumn 9, Issue 1, 2018, Pages

Multiplex glycan bead array for high throughput and high content analyses of glycan binding proteins

Author keywords

[No Author keywords available]

Indexed keywords

BINDING PROTEIN; CD33 ANTIGEN; ENDOTHELIAL LEUKOCYTE ADHESION MOLECULE 1; GALECTIN 3; GLYCAN; GLYCAN ANTIBODY; GLYCAN BINDING PROTEIN; IMMUNOGLOBULIN G ANTIBODY; IMMUNOGLOBULIN M ANTIBODY; LECTIN; N ACETYLNEURAMINIC ACID; PLANT LECTIN; PROTEIN ANTIBODY; SIALIC ACID BINDING IMMUNOGLOBULIN LIKE LECTIN; SIGLEC 5; UNCLASSIFIED DRUG; ANTIBODY; POLYSACCHARIDE; TUMOR MARKER;

EID: 85041391574     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/s41467-017-02747-y     Document Type: Article
Times cited : (62)

References (54)
  • 1
    • 0030745147 scopus 로고    scopus 로고
    • Perspectives on the significance of altered glycosylation of glycoproteins in cancer
    • Kim, Y. J. & Varki, A. Perspectives on the significance of altered glycosylation of glycoproteins in cancer. Glycoconj. J. 14, 569-576 (1997).
    • (1997) Glycoconj. J. , vol.14 , pp. 569-576
    • Kim, Y.J.1    Varki, A.2
  • 2
    • 0025614713 scopus 로고
    • Altered glycosylation of human chorionic gonadotropin decreases its hormonal activity as determined by cyclicadenosine 3', 5'-monophosphate production in MA-10 cells
    • Amano, J., Nishimura, R., Sato, S. & Kobata, A. Altered glycosylation of human chorionic gonadotropin decreases its hormonal activity as determined by cyclicadenosine 3', 5'-monophosphate production in MA-10 cells. Glycobiology 1, 45-50 (1990).
    • (1990) Glycobiology , vol.1 , pp. 45-50
    • Amano, J.1    Nishimura, R.2    Sato, S.3    Kobata, A.4
  • 3
    • 67650112659 scopus 로고    scopus 로고
    • Targeted glycoproteomic identification of cancer cell glycosylation
    • Powlesland, A. S. et al. Targeted glycoproteomic identification of cancer cell glycosylation. Glycobiology 19, 899-909 (2009).
    • (2009) Glycobiology , vol.19 , pp. 899-909
    • Powlesland, A.S.1
  • 4
    • 54949106904 scopus 로고    scopus 로고
    • Mammalian glycosylation in immunity
    • Marth, J. D. & Grewal, P. K. Mammalian glycosylation in immunity. Nat. Rev. Immunol. 8, 874-887 (2008).
    • (2008) Nat. Rev. Immunol. , vol.8 , pp. 874-887
    • Marth, J.D.1    Grewal, P.K.2
  • 5
    • 50449083310 scopus 로고    scopus 로고
    • Evaluation of the serum N-linked glycome for the diagnosis of cancer and chronic inflammation
    • Arnold, J. N., Saldova, R., Hamid, U. M. & Rudd, P. M. Evaluation of the serum N-linked glycome for the diagnosis of cancer and chronic inflammation. Proteomics 8, 3284-3293 (2008).
    • (2008) Proteomics , vol.8 , pp. 3284-3293
    • Arnold, J.N.1    Saldova, R.2    Hamid, U.M.3    Rudd, P.M.4
  • 6
    • 0004106191 scopus 로고    scopus 로고
    • 2nd edn eds Varki, A et al. Cold Spring Harbor, NY
    • Varki, A. & Lowe, J. B. in Essentials of Glycobiology, 2nd edn (eds Varki, A. et al.) (Cold Spring Harbor, NY, 2009).
    • (2009) Essentials of Glycobiology
    • Varki, A.1    Lowe, J.B.2
  • 7
    • 70349286700 scopus 로고    scopus 로고
    • Profiling human serum antibodies with a carbohydrate antigen microarray
    • Oyelaran, O., McShane, L. M., Dodd, L. & Gildersleeve, J. C. Profiling human serum antibodies with a carbohydrate antigen microarray. J. Proteome Res. 8, 4301-4310 (2009).
    • (2009) J. Proteome Res. , vol.8 , pp. 4301-4310
    • Oyelaran, O.1    McShane, L.M.2    Dodd, L.3    Gildersleeve, J.C.4
  • 8
    • 84862882393 scopus 로고    scopus 로고
    • Repertoire of human natural anti-glycan immunoglobulins. Do we have auto-antibodies?
    • Bovin, N. et al. Repertoire of human natural anti-glycan immunoglobulins. Do we have auto-antibodies? Biochim. Biophys. Acta 1820, 1373-1382 (2012).
    • (2012) Biochim. Biophys. Acta , vol.1820 , pp. 1373-1382
    • Bovin, N.1
  • 9
    • 84899630848 scopus 로고    scopus 로고
    • Humoral response to a viral glycan correlates with survival on PROSTVAC-VF
    • Campbell, C. T. et al. Humoral response to a viral glycan correlates with survival on PROSTVAC-VF. Proc. Natl Acad. Sci. USA 111, E1749-E1758 (2014).
    • (2014) Proc. Natl Acad. Sci. USA , vol.111 , pp. E1749-E1758
    • Campbell, C.T.1
  • 10
    • 84866393051 scopus 로고    scopus 로고
    • Serum anti-glycan antibody biomarkers for inflammatory bowel disease diagnosis and progression: A systematic review and meta-analysis
    • Kaul, A. et al. Serum anti-glycan antibody biomarkers for inflammatory bowel disease diagnosis and progression: A systematic review and meta-analysis. Inflamm. Bowel Dis. 18, 1872-1884 (2012).
    • (2012) Inflamm. Bowel Dis. , vol.18 , pp. 1872-1884
    • Kaul, A.1
  • 11
    • 36248972262 scopus 로고    scopus 로고
    • Ovarian cancer is associated with changes in glycosylation in both acute-phase proteins and IgG
    • Saldova, R. et al. Ovarian cancer is associated with changes in glycosylation in both acute-phase proteins and IgG. Glycobiology 17, 1344-1356 (2007).
    • (2007) Glycobiology , vol.17 , pp. 1344-1356
    • Saldova, R.1
  • 12
    • 78650870657 scopus 로고    scopus 로고
    • Shotgun glycomics: A microarray strategy for functional glycomics
    • Song, X. et al. Shotgun glycomics: A microarray strategy for functional glycomics. Nat. Methods 8, 85-90 (2011).
    • (2011) Nat. Methods , vol.8 , pp. 85-90
    • Song, X.1
  • 13
    • 58549107432 scopus 로고    scopus 로고
    • Novel fluorescent glycan microarray strategy reveals ligands for galectins
    • Song, X. et al. Novel fluorescent glycan microarray strategy reveals ligands for galectins. Chem. Biol. 16, 36-47 (2009).
    • (2009) Chem. Biol. , vol.16 , pp. 36-47
    • Song, X.1
  • 14
    • 84910642776 scopus 로고    scopus 로고
    • Human milk contains novel glycans that are potential decoy receptors for neonatal rotaviruses
    • Yu, Y. et al. Human milk contains novel glycans that are potential decoy receptors for neonatal rotaviruses. Mol. Cell. Proteom. 13, 2944-2960 (2014).
    • (2014) Mol. Cell. Proteom. , vol.13 , pp. 2944-2960
    • Yu, Y.1
  • 15
    • 82355183895 scopus 로고    scopus 로고
    • Measurement of antibodies to pneumococcal polysaccharides with Luminex xMAP microsphere-based liquid arrays
    • Pickering, J. W. & Hill, H. R. Measurement of antibodies to pneumococcal polysaccharides with Luminex xMAP microsphere-based liquid arrays. Methods Mol. Biol. 808, 361-375 (2012).
    • (2012) Methods Mol. Biol. , vol.808 , pp. 361-375
    • Pickering, J.W.1    Hill, H.R.2
  • 16
    • 79951978556 scopus 로고    scopus 로고
    • Microbead-based immunoassay for simultaneous detection of Shiga toxins and isolation of Escherichia coli O157 in foods
    • Clotilde, L. M., Bernard, Ct, Hartman, G. L., Lau, D. K. & Carter, J. M. Microbead-based immunoassay for simultaneous detection of Shiga toxins and isolation of Escherichia coli O157 in foods. J. Food Prot. 74, 373-379 (2011).
    • (2011) J. Food Prot. , vol.74 , pp. 373-379
    • Clotilde, L.M.1    Bernard, C.T.2    Hartman, G.L.3    Lau, D.K.4    Carter, J.M.5
  • 17
    • 0036322989 scopus 로고    scopus 로고
    • A multiplexed fluorescent microsphere immunoassay for antibodies to pneumococcal capsular polysaccharides
    • Pickering, J. W. et al. A multiplexed fluorescent microsphere immunoassay for antibodies to pneumococcal capsular polysaccharides. Am. J. Clin. Pathol. 117, 589-596 (2002).
    • (2002) Am. J. Clin. Pathol. , vol.117 , pp. 589-596
    • Pickering, J.W.1
  • 18
    • 84879442945 scopus 로고    scopus 로고
    • Use of Luminex MagPlex magnetic microspheres for highthroughput spoligotyping of Mycobacterium tuberculosis isolates in Port-au-Prince, Haiti
    • Ocheretina, O. et al. Use of Luminex MagPlex magnetic microspheres for highthroughput spoligotyping of Mycobacterium tuberculosis isolates in Port-au-Prince, Haiti. J. Clin. Microbiol. 51, 2232-2237 (2013).
    • (2013) J. Clin. Microbiol. , vol.51 , pp. 2232-2237
    • Ocheretina, O.1
  • 19
    • 77957860638 scopus 로고    scopus 로고
    • New serologic markers for inflammatory bowel disease diagnosis
    • Dotan, I. New serologic markers for inflammatory bowel disease diagnosis. Dig. Dis. 28, 418-423 (2010).
    • (2010) Dig. Dis. , vol.28 , pp. 418-423
    • Dotan, I.1
  • 20
    • 66949132914 scopus 로고    scopus 로고
    • Novel anti-glycan antibodies related to inflammatory bowel disease diagnosis and phenotype
    • Seow, C. H. et al. Novel anti-glycan antibodies related to inflammatory bowel disease diagnosis and phenotype. Am. J. Gastroenterol. 104, 1426-1434 (2009).
    • (2009) Am. J. Gastroenterol. , vol.104 , pp. 1426-1434
    • Seow, C.H.1
  • 21
    • 73349143612 scopus 로고    scopus 로고
    • Laboratory diagnosis of specific antibody deficiency to pneumococcal capsular polysaccharide antigens by multiplexed bead assay
    • Borgers, H. et al. Laboratory diagnosis of specific antibody deficiency to pneumococcal capsular polysaccharide antigens by multiplexed bead assay. Clin. Immunol. 134, 198-205 (2010).
    • (2010) Clin. Immunol. , vol.134 , pp. 198-205
    • Borgers, H.1
  • 22
    • 80054732170 scopus 로고    scopus 로고
    • Serum antiglycan antibody detection of nonmucinous ovarian cancers by using a printed glycan array
    • Jacob, F. et al. Serum antiglycan antibody detection of nonmucinous ovarian cancers by using a printed glycan array. Int. J. Cancer 130, 138-146 (2012).
    • (2012) Int. J. Cancer , vol.130 , pp. 138-146
    • Jacob, F.1
  • 23
    • 85012009737 scopus 로고    scopus 로고
    • Naturally occurring anti-glycan antibodies binding to Globo H-expressing cells identify ovarian cancer patients
    • Pochechueva, T. et al. Naturally occurring anti-glycan antibodies binding to Globo H-expressing cells identify ovarian cancer patients. J. Ovarian Res. 10, 8 (2017).
    • (2017) J. Ovarian Res. , vol.10 , pp. 8
    • Pochechueva, T.1
  • 24
    • 84908450036 scopus 로고    scopus 로고
    • PEGylation of microbead surfaces reduces unspecific antibody binding in glycan-based suspension array
    • Pochechueva, T. et al. PEGylation of microbead surfaces reduces unspecific antibody binding in glycan-based suspension array. J. Immunol. Methods 412, 42-52 (2014).
    • (2014) J. Immunol. Methods , vol.412 , pp. 42-52
    • Pochechueva, T.1
  • 25
    • 78751516772 scopus 로고    scopus 로고
    • Multiplex suspension array for human anti-carbohydrate antibody profiling
    • Pochechueva, T. et al. Multiplex suspension array for human anti-carbohydrate antibody profiling. Analyst 136, 560-569 (2011).
    • (2011) Analyst , vol.136 , pp. 560-569
    • Pochechueva, T.1
  • 26
    • 84863798606 scopus 로고    scopus 로고
    • Comparison of printed glycan array, suspension array and ELISA in the detection of human anti-glycan antibodies
    • Pochechueva, T. et al. Comparison of printed glycan array, suspension array and ELISA in the detection of human anti-glycan antibodies. Glycoconj. J. 28, 507-517 (2011).
    • (2011) Glycoconj. J. , vol.28 , pp. 507-517
    • Pochechueva, T.1
  • 27
    • 84921798105 scopus 로고    scopus 로고
    • Luminex((R)) multiplex bead suspension arrays for the detection and serotyping of Salmonella spp
    • Dunbar, S. A., Ritchie, V. B., Hoffmeyer, M. R., Rana, G. S. & Zhang, H. Luminex((R)) multiplex bead suspension arrays for the detection and serotyping of Salmonella spp. Methods Mol. Biol. 1225, 1-27 (2015).
    • (2015) Methods Mol. Biol. , vol.1225 , pp. 1-27
    • Dunbar, S.A.1    Ritchie, V.B.2    Hoffmeyer, M.R.3    Rana, G.S.4    Zhang, H.5
  • 30
    • 84959419072 scopus 로고    scopus 로고
    • Development of a luminex bead based assay for diagnosis of toxocariasis using recombinant antigens Tc-CTL-1 and Tc-TES-26
    • Anderson, J. P. et al. Development of a luminex bead based assay for diagnosis of toxocariasis using recombinant antigens Tc-CTL-1 and Tc-TES-26. PLoS Negl. Trop. Dis. 9, e0004168 (2015).
    • (2015) PLoS Negl. Trop. Dis. , vol.9 , pp. e0004168
    • Anderson, J.P.1
  • 31
    • 84941711551 scopus 로고    scopus 로고
    • Efficient chemoenzymatic synthesis of an N-glycan isomer library
    • Li, L. et al. Efficient chemoenzymatic synthesis of an N-glycan isomer library. Chem. Sci. 6, 5652-5661 (2015).
    • (2015) Chem. Sci. , vol.6 , pp. 5652-5661
    • Li, L.1
  • 32
    • 70349281524 scopus 로고    scopus 로고
    • Fluorescent glycosylamides produced by microscale derivatization of free glycans for natural glycan microarrays
    • Song, X., Lasanajak, Y., Xia, B., Smith, D. F. & Cummings, R. D. Fluorescent glycosylamides produced by microscale derivatization of free glycans for natural glycan microarrays. ACS Chem. Biol. 4, 741-750 (2009).
    • (2009) ACS Chem. Biol. , vol.4 , pp. 741-750
    • Song, X.1    Lasanajak, Y.2    Xia, B.3    Smith, D.F.4    Cummings, R.D.5
  • 33
    • 84907128853 scopus 로고
    • Histochemical specificity of beta-galactose binding lectins from Arachis hypogaea (peanut) and Ricinus communis (castor bean)
    • Hennigar, L. M., Hennigar, R. A. & Schulte, B. A. Histochemical specificity of beta-galactose binding lectins from Arachis hypogaea (peanut) and Ricinus communis (castor bean). Stain. Technol. 62, 317-325 (1987).
    • (1987) Stain. Technol. , vol.62 , pp. 317-325
    • Hennigar, L.M.1    Hennigar, R.A.2    Schulte, B.A.3
  • 34
    • 84871757404 scopus 로고    scopus 로고
    • Functional glycomic analysis of human milk glycans reveals the presence of virus receptors and embryonic stem cell biomarkers
    • Yu, Y. et al. Functional glycomic analysis of human milk glycans reveals the presence of virus receptors and embryonic stem cell biomarkers. J. Biol. Chem. 287, 44784-44799 (2012).
    • (2012) J. Biol. Chem. , vol.287 , pp. 44784-44799
    • Yu, Y.1
  • 35
    • 10344233222 scopus 로고    scopus 로고
    • Printed covalent glycan array for ligand profiling of diverse glycan binding proteins
    • Blixt, O. et al. Printed covalent glycan array for ligand profiling of diverse glycan binding proteins. Proc. Natl Acad. Sci. USA 101, 17033-17038 (2004).
    • (2004) Proc. Natl Acad. Sci. USA , vol.101 , pp. 17033-17038
    • Blixt, O.1
  • 36
    • 14244269760 scopus 로고    scopus 로고
    • Glycan array screening reveals a candidate ligand for Siglec-8
    • Bochner, B. S. et al. Glycan array screening reveals a candidate ligand for Siglec-8 J. Biol. Chem. 280, 4307-4312 (2005).
    • (2005) J. Biol. Chem. , vol.280 , pp. 4307-4312
    • Bochner, B.S.1
  • 37
    • 84892941529 scopus 로고    scopus 로고
    • Serum protein profile at remission can accurately assess therapeutic outcomes and survival for serous ovarian cancer
    • Wang, J. et al. Serum protein profile at remission can accurately assess therapeutic outcomes and survival for serous ovarian cancer. PLoS ONE 8, e78393 (2013).
    • (2013) PLoS ONE , vol.8 , pp. e78393
    • Wang, J.1
  • 38
    • 85021889822 scopus 로고    scopus 로고
    • Why human anti-Galalpha1-4Galbeta1-4Glc natural antibodies do not recognize the trisaccharide on erythrocyte membrane? Molecular dynamics and immunochemical investigation
    • Volynsky, P. et al. Why human anti-Galalpha1-4Galbeta1-4Glc natural antibodies do not recognize the trisaccharide on erythrocyte membrane? Molecular dynamics and immunochemical investigation. Mol. Immunol. 90, 87-97 (2017).
    • (2017) Mol. Immunol. , vol.90 , pp. 87-97
    • Volynsky, P.1
  • 39
    • 70349117661 scopus 로고    scopus 로고
    • Glycan arrays: Recent advances and future challenges
    • Oyelaran, O. & Gildersleeve, J. C. Glycan arrays: recent advances and future challenges. Curr. Opin. Chem. Biol. 13, 406-413 (2009).
    • (2009) Curr. Opin. Chem. Biol. , vol.13 , pp. 406-413
    • Oyelaran, O.1    Gildersleeve, J.C.2
  • 40
    • 37149047055 scopus 로고    scopus 로고
    • Application of carbohydrate array technology to antigen discovery and vaccine development
    • Oyelaran, O. & Gildersleeve, J. C. Application of carbohydrate array technology to antigen discovery and vaccine development. Expert. Rev. Vaccin. 6, 957-969 (2007).
    • (2007) Expert. Rev. Vaccin. , vol.6 , pp. 957-969
    • Oyelaran, O.1    Gildersleeve, J.C.2
  • 42
    • 84964763166 scopus 로고    scopus 로고
    • Development of a custom pentaplex sandwich immunoassay using Protein-G coupled beads for the Luminex(R) xMAP(R) platform
    • McDonald, J. U., Ekeruche-Makinde, J., Ho, M. M., Tregoning, J. S. & Ashiru, O. Development of a custom pentaplex sandwich immunoassay using Protein-G coupled beads for the Luminex(R) xMAP(R) platform. J. Immunol. Methods 433, 6-16 (2016).
    • (2016) J. Immunol. Methods , vol.433 , pp. 6-16
    • McDonald, J.U.1    Ekeruche-Makinde, J.2    Ho, M.M.3    Tregoning, J.S.4    Ashiru, O.5
  • 43
    • 84908890596 scopus 로고    scopus 로고
    • Affinity proteomic profiling of plasma, cerebrospinal fluid, and brain tissue within multiple sclerosis
    • Bystrom, S. et al. Affinity proteomic profiling of plasma, cerebrospinal fluid, and brain tissue within multiple sclerosis. J. Proteome Res. 13, 4607-4619 (2014).
    • (2014) J. Proteome Res. , vol.13 , pp. 4607-4619
    • Bystrom, S.1
  • 44
    • 84959220664 scopus 로고    scopus 로고
    • Anoctamin 2 identified as an autoimmune target in multiple sclerosis
    • Ayoglu, B. et al. Anoctamin 2 identified as an autoimmune target in multiple sclerosis. Proc. Natl Acad. Sci. USA 113, 2188-2193 (2016).
    • (2016) Proc. Natl Acad. Sci. USA , vol.113 , pp. 2188-2193
    • Ayoglu, B.1
  • 45
    • 80054863376 scopus 로고    scopus 로고
    • A chemical-genetic screen reveals a mechanism of resistance to PI3K inhibitors in cancer
    • Muellner, M. K. et al. A chemical-genetic screen reveals a mechanism of resistance to PI3K inhibitors in cancer. Nat. Chem. Biol. 7, 787-793 (2011).
    • (2011) Nat. Chem. Biol. , vol.7 , pp. 787-793
    • Muellner, M.K.1
  • 46
    • 60149089005 scopus 로고    scopus 로고
    • Bead-based profiling of tyrosine kinase phosphorylation identifies SRC as a potential target for glioblastoma therapy
    • Du, J. et al. Bead-based profiling of tyrosine kinase phosphorylation identifies SRC as a potential target for glioblastoma therapy. Nat. Biotechnol. 27, 77-83 (2009).
    • (2009) Nat. Biotechnol. , vol.27 , pp. 77-83
    • Du, J.1
  • 47
    • 20444460289 scopus 로고    scopus 로고
    • MicroRNA expression profiles classify human cancers
    • Lu, J. et al. MicroRNA expression profiles classify human cancers. Nature 435, 834-838 (2005).
    • (2005) Nature , vol.435 , pp. 834-838
    • Lu, J.1
  • 48
    • 33747657739 scopus 로고    scopus 로고
    • A method for high-throughput gene expression signature analysis
    • Peck, D. et al. A method for high-throughput gene expression signature analysis. Genome Biol. 7, R61 (2006).
    • (2006) Genome Biol , vol.7 , pp. R61
    • Peck, D.1
  • 49
    • 79952440160 scopus 로고    scopus 로고
    • Antiglycan antibodies in Greek patients with inflammatory bowel disease
    • Koutroubakis, I. E. et al. Antiglycan antibodies in Greek patients with inflammatory bowel disease. Dig. Dis. Sci. 56, 845-852 (2011).
    • (2011) Dig. Dis. Sci. , vol.56 , pp. 845-852
    • Koutroubakis, I.E.1
  • 50
    • 58149240444 scopus 로고    scopus 로고
    • New serological biomarkers of inflammatory bowel disease
    • Li, X., Conklin, L. & Alex, P. New serological biomarkers of inflammatory bowel disease. World J. Gastroenterol. 14, 5115-5124 (2008).
    • (2008) World J. Gastroenterol. , vol.14 , pp. 5115-5124
    • Li, X.1    Conklin, L.2    Alex, P.3
  • 51
    • 33746542174 scopus 로고    scopus 로고
    • Antibodies against laminaribioside and chitobioside are novel serologic markers in Crohn's disease
    • Dotan, I. et al. Antibodies against laminaribioside and chitobioside are novel serologic markers in Crohn's disease. Gastroenterology 131, 366-378 (2006).
    • (2006) Gastroenterology , vol.131 , pp. 366-378
    • Dotan, I.1
  • 52
    • 84874880999 scopus 로고    scopus 로고
    • Serum antibodies to blood group A predict survival on PROSTVAC-VF
    • Campbell, C. T. et al. Serum antibodies to blood group A predict survival on PROSTVAC-VF. Clin. Cancer Res. 19, 1290-1299 (2013).
    • (2013) Clin. Cancer Res. , vol.19 , pp. 1290-1299
    • Campbell, C.T.1
  • 53
    • 33751363180 scopus 로고    scopus 로고
    • Arraying glycomics: A novel bi-functional spacer for one-step microscale derivatization of free reducing glycans
    • Bohorov, O., Andersson-Sand, H., Hoffmann, J. & Blixt, O. Arraying glycomics: A novel bi-functional spacer for one-step microscale derivatization of free reducing glycans. Glycobiology 16, 21c-27c (2006).
    • (2006) Glycobiology , vol.16 , pp. 21c-27c
    • Bohorov, O.1    Andersson-Sand, H.2    Hoffmann, J.3    Blixt, O.4
  • 54
    • 0023869530 scopus 로고
    • An inhibition enzyme immunoassay for estimating relative antibody affinity and affinity heterogeneity
    • Rath, S., Stanley, C. M. & Steward, M. W. An inhibition enzyme immunoassay for estimating relative antibody affinity and affinity heterogeneity. J. Immunol. Methods 106, 245-249 (1988).
    • (1988) J. Immunol. Methods , vol.106 , pp. 245-249
    • Rath, S.1    Stanley, C.M.2    Steward, M.W.3


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