Association of red blood cell transfusion and short- and longer-term mortality after coronary artery bypass graft surgery

Journal of Cardiothoracic and Vascular Anesthesia

Volumn 32, Issue 3, 2018, Pages 1225-1232

  Tantawy, Hossam ^a   Li, Alice ^b   Dai, Feng ^c   Elgammal, Mohamed ^a   Sukumar, Nitin ^c   Elefteriades, John ^a   Akhtar, Shamsuddin ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c YALE UNIVERSITY   (United States)

Author keywords

coronary artery bypass; outcome; red blood cell transfusion

Indexed keywords

ADULT; AGED; ARTICLE; CLINICAL OUTCOME; CONTROLLED STUDY; CORONARY ARTERY BYPASS GRAFT; ERYTHROCYTE TRANSFUSION; FEMALE; HOSPITAL MORTALITY; HUMAN; MAJOR CLINICAL STUDY; MALE; MEDICAL RECORD REVIEW; MORTALITY RATE; OBSERVATIONAL STUDY; PRIORITY JOURNAL; RETROSPECTIVE STUDY; FACTUAL DATABASE; MIDDLE AGED; MORTALITY; POSTOPERATIVE COMPLICATION; TIME FACTOR; TRENDS; VERY ELDERLY;

AGED; AGED, 80 AND OVER; CORONARY ARTERY BYPASS; DATABASES, FACTUAL; ERYTHROCYTE TRANSFUSION; FEMALE; HOSPITAL MORTALITY; HUMANS; MALE; MIDDLE AGED; POSTOPERATIVE COMPLICATIONS; RETROSPECTIVE STUDIES; TIME FACTORS;

EID: 85041298655     PISSN: 10530770     EISSN: 15328422     Source Type: Journal    
DOI: 10.1053/j.jvca.2017.12.033     Document Type: Article

References (36)

1. Sahu, S., Hemlata, Verma, A., Adverse events related to blood transfusion. Indian J Anaesth 58 (2014), 543–551.
2. Gerber, D.R., Risks of packed red blood cell transfusion in patients undergoing cardiac surgery. J Crit Care, 27, 2012, 737 e731–9.
3. Murphy, G.J., Reeves, B.C., Rogers, C.A., et al. Increased mortality, postoperative morbidity, and cost after red blood cell transfusion in patients having cardiac surgery. Circulation 116 (2007), 2544–2552.
4. Kumar, A., Figueroa, P.I., Gowans, K.L., et al. An evolution in blood management: Past, present, and future. Qual Manage Health Care 20 (2011), 311–321.
5. Society of Thoracic Surgeons Blood Conservation Guideline Task Force, Ferraris, V.A., Ferraris, S.P., et al. Perioperative blood transfusion and blood conservation in cardiac surgery: the Society of Thoracic Surgeons and The Society of Cardiovascular Anesthesiologists clinical practice guideline. Ann Thorac Surg 83 (2007), S27–S86.
6. Hajjar, L.A., Vincent, J.L., Galas, F.R., et al. Transfusion requirements after cardiac surgery: The TRACS randomized controlled trial. JAMA 304 (2010), 1559–1567.
7. Hebert, P.C., Wells, G., Blajchman, M.A., et al. A multicenter, randomized, controlled clinical trial of transfusion requirements in critical care. Transfusion Requirements in Critical Care Investigators, Canadian Critical Care Trials Group. N Engl J Med 340 (1999), 409–417.
8. Cooper, H.A., Rao, S.V., Greenberg, M.D., et al. Conservative versus liberal red cell transfusion in acute myocardial infarction (the CRIT Randomized Pilot Study). Am J Cardiol 108 (2011), 1108–1111.
9. Carson, J.L., Brooks, M.M., Abbott, J.D., et al. Liberal versus restrictive transfusion thresholds for patients with symptomatic coronary artery disease. Am Heart J, 165(964–71), 2013, e961.
10. Bracey, A.W., Radovancevic, R., Riggs, S.A., et al. Lowering the hemoglobin threshold for transfusion in coronary artery bypass procedures: Effect on patient outcome. Transfusion 39 (1999), 1070–1077.
11. Nakamura, R.E., Vincent, J.L., Fukushima, J.T., et al. A liberal strategy of red blood cell transfusion reduces cardiogenic shock in elderly patients undergoing cardiac surgery. J Thorac Cardiovasc Surg 150 (2015), 1314–1320.
12. Paone, G., Likosky, D.S., Brewer, R., et al. Transfusion of 1 and 2 units of red blood cells is associated with increased morbidity and mortality. Ann Thorac Surg 97 (2014), 87–93 discussion 93–4.
13. Surgenor, S.D., Kramer, R.S., Olmstead, E.M., et al. The association of perioperative red blood cell transfusions and decreased long-term survival after cardiac surgery. Anesth Analg 108 (2009), 1741–1746.
14. Murphy, G.J., Pike, K., Rogers, C.A., et al. Liberal or restrictive transfusion after cardiac surgery. N Engl J Med 372 (2015), 997–1008.
15. Guyatt, G., Gutterman, D., Baumann, M.H., et al. Grading strength of recommendations and quality of evidence in clinical guidelines: Report from an american college of chest physicians task force. Chest 129 (2006), 174–181.
16. Bennett-Guerrero, E., Zhao, Y., O'Brien, S.M., et al. Variation in use of blood transfusion in coronary artery bypass graft surgery. JAMA 304 (2010), 1568–1575.
17. Maddux, F.W., Dickinson, T.A., Rilla, D., et al. Institutional variability of intraoperative red blood cell utilization in coronary artery bypass graft surgery. Am J Med Qual 24 (2009), 403–411.
18. Shehata, N., Wilson, K., Mazer, C.D., et al. The proportion of variation in perioperative transfusion decisions in Canada attributable to the hospital. Can J Anaesth 54 (2007), 902–907.
19. Shehata, N., Burns, L.A., Nathan, H., et al. A randomized controlled pilot study of adherence to transfusion strategies in cardiac surgery. Transfusion 52 (2012), 91–99.
20. Koch, C.G., Li, L., Duncan, A.I., et al. Morbidity and mortality risk associated with red blood cell and blood-component transfusion in isolated coronary artery bypass grafting. Crit Care Med 34 (2006), 1608–1616.
21. Whitson, B.A., Huddleston, S.J., Savik, K., et al. Risk of adverse outcomes associated with blood transfusion after cardiac surgery depends on the amount of transfusion. J Surg Res 158 (2010), 20–27.
22. D'Agostino, R.B. Jr., Propensity score methods for bias reduction in the comparison of a treatment to a non-randomized control group. Stat Med 17 (1998), 2265–2281.
23. Parsons, L.S., Reducing bias in a propensity score matched-pair sample using greedy matching techniques. 2001, Proceedings of the Conference Reducing bias in a propensity score matched-pair sample using greedy matching techniques, SAS Institute Inc, Cary, NC, 214–226.
24. Austin, P.C., Balance diagnostics for comparing the distribution of baseline covariates between treatment groups in propensity-score matched samples. Stat Med 28 (2009), 3083–3107.
25. nd ed, 1988, Lawrence Erlbaum Associates, Hillsdale, NJ.
26. Mazer, C.D., Whitlock, R.P., Fergusson, D.A., et al. Restrictive or liberal red-cell transfusion for cardiac surgery. N Engl J Med 377 (2017), 2133–2144.
27. Koch, C.G., Sessler, D.I., Mascha, E.J., et al. A randomized clinical trial of red blood cell transfusion triggers in cardiac surgery. Ann Thorac Surg 104 (2017), 1243–1250.
28. Koster, A., Zittermann, A., Borgermann, J., et al. Transfusion of 1 and 2 units of red blood cells does not increase mortality and organ failure in patients undergoing isolated coronary artery bypass grafting. Eur J Cardiothorac Surg 49 (2016), 931–936.
29. Dixon, B., Santamaria, J.D., Reid, D., et al. The association of blood transfusion with mortality after cardiac surgery: cause or confounding? (CME). Transfusion 53 (2013), 19–27.
30. Santos, A.A., Sousa, A.G., Piotto, R.F., et al. Mortality risk is dose-dependent on the number of packed red blood cell transfused after coronary artery bypass graft. Rev Bras Cir Cardiovasc 28 (2013), 509–517.
31. Paone, G., Herbert, M.A., Theurer, P.F., et al. Red blood cells and mortality after coronary artery bypass graft surgery: An analysis of 672 operative deaths. Ann Thorac Surg 99 (2015), 1583–1589 discussion 1589–90.
32. Bjursten, H., Dardashti, A., Ederoth, P., et al. Increased long-term mortality with plasma transfusion after coronary artery bypass surgery. Intensive Care Med 39 (2013), 437–444.
33. Loor, G., Rajeswaran, J., Li, L., et al. The least of 3 evils: Exposure to red blood cell transfusion, anemia, or both?. J Thorac Cardiovasc Surg 146 (2013), 1480–1487 e1486.
34. Murphy, M.F., Murphy, G.J., Gill, R., et al. National comparative audit of blood transfusion: 2011 audit of blood transfusion in adult cardiac surgery. 2013, National Health Service, Birmingham, UK, 40.
35. Yun, J.J., Helm, R.E., Kramer, R.S., et al. Limited blood transfusion does not impact survival in octogenarians undergoing cardiac operations. Ann Thorac Surg 94 (2012), 2038–2045.
36. Chen, J.W., Hsu, R.B., Impact of surgeon experience on the rate of blood transfusion in off-pump coronary artery bypass. J Formos Med Assoc 115 (2016), 145–151.