Low carbohydrate diets may increase risk of neural tube defects

Birth Defects Research

Volumn 110, Issue 11, 2018, Pages 901-909

  Desrosiers, Tania A ^a   Siega Riz, Anna Maria ^a,b   Mosley, Bridget S ^c   Meyer, Robert E ^a,d  

^a University of North Carolina at Chapel Hill   (United States)

^b University of North Carolina   (United States)

^c UNIVERSITY OF COLORADO   (United States)

^d North Carolina Division of Public Health   (United States)

Author keywords

birth defects; carbohydrate restricted; carbohydrates; diet; folic acid; neural tube defects

Indexed keywords

CARBOHYDRATE; FOLIC ACID;

ADULT; ANENCEPHALUS; ARTICLE; CALORIC INTAKE; CASE CONTROL STUDY; CLINICAL ASSESSMENT; CONCEPTION; CONGENITAL MALFORMATION; CONTROLLED STUDY; DIETARY INTAKE; FOOD FREQUENCY QUESTIONNAIRE; HUMAN; INTERVIEW; LOW CARBOHYDRATE DIET; MAJOR CLINICAL STUDY; MULTICENTER STUDY; NEURAL TUBE DEFECT; PREGNANCY; PREGNANCY TERMINATION; PREVALENCE; QUESTIONNAIRE; SPINAL DYSRAPHISM; STILLBIRTH; YOUNG ADULT; FEMALE; MALE; RISK FACTOR;

ADULT; DIET, CARBOHYDRATE-RESTRICTED; FEMALE; HUMANS; MALE; NEURAL TUBE DEFECTS; RISK FACTORS; YOUNG ADULT;

EID: 85041045994     PISSN: None     EISSN: 24721727     Source Type: Journal    
DOI: 10.1002/bdr2.1198     Document Type: Article

References (24)

1. Blanck, H. M., Gillespie, C., Serdula, M. K., Khan, L. K., Galusk, D. A., & Ainsworth, B. E. (2006). Use of low-carbohydrate, high-protein diets among Americans: Correlates, duration, and weight loss. MedGenMed: Medscape general Medicine, 8(2), 5.
2. Carmichael, S. L., Rasmussen, S. A., & Shaw, G. M. (2010). Prepregnancy obesity: A complex risk factor for selected birth defects. Birth Defects Research. Part A, Clinical and Molecular Teratology, 88(10), 804–810.
3. Carmichael, S. L., Shaw, G. M., Schaffer, D. M., Laurent, C., & Selvin, S. (2003). Dieting behaviors and risk of neural tube defects. American Journal of Epidemiology, 158(12), 1127–1131.
4. Carmichael, S. L., Yang, W., & Feldkamp, M. L. (2012). Reduced risks of neural tube defects and orofacial clefts with higher diet quality. Archives of Pediatrics & Adolescent Medicine, 166(2), 121–126.
5. Dott, M., Rasmussen, S. A., Hogue, C. J., Reefhuis, J., & National Birth Defects Prevention Study. (2010). Association between pregnancy intention and reproductive-health related behaviors before and after pregnancy recognition, National Birth Defects Prevention Study, 1997–2002. Maternal and Child Health Journal, 14(3), 373–381.
6. Dugan, A. (2014, July 29). Americans still avoid fat more than carbs. Gallup News. Retrieved from http://news.gallup.com/poll/174176/americans-avoid-fat-carbs.aspx.
7. Feinman, R. D., Pogozelski, W. K., Astrup, A., Bernstein, R. K., Fine, E. J., Westman, E. C., … Worm, N. (2015). Dietary carbohydrate restriction as the first approach in diabetes management: Critical review and evidence base. Nutrition, 31(1), 1–13.
8. Food and Drug Administration. (1996). Food standards: Amendment of standards of identity for enriched grain products to require addition of folic acid. Federal Register, 61, 8781–8797.
9. Freedman, M. R., King, J., & Kennedy, E. (2001). Popular diets: A scientific review. Obesity Research, 9(Suppl 1), 1S–40S.
10. Hamner, H. C., & Tinker, S. C. (2014). Fortification of corn masa flour with folic acid in the United States: An overview of the evidence. Annals of the New York Academy of Sciences, 1312, 8–14.
11. Mosley, B. S., Cleves, M. A., Siega-Riz, A. M., Shaw, G. M., Canfield, M. A., Waller, D. K., … National Birth Defects Prevention Study. (2009). Neural tube defects and maternal folate intake among pregnancies conceived after folic acid fortification in the United States. American Journal of Epidemiology, 169(1), 9–17.
12. Ornoy, A., Reece, E. A., Pavlinkova, G., Kappen, C., & Miller, R. K. (2015). Effect of maternal diabetes on the embryo, fetus, and children: Congenital anomalies, genetic and epigenetic changes and developmental outcomes. Birth Defects Research. Part C, Embryo Today: Reviews, 105(1), 53–72.
13. Pehrsson, P., Patterson, K., Haytowitz, D., & Phillips, K. (2015). Total carbohydrate determinations in USDA's National Nutrient Database for Standard Reference. The FASEB Journal, 29(1): S740.6.
14. Quinlivan, E. P., & Gregory, J. F., 3rd. (2007). Reassessing folic acid consumption patterns in the United States (1999 2004): Potential effect on neural tube defects and overexposure to folate. The American Journal of Clinical Nutrition, 86(6), 1773–1779.
15. Rasmussen, S. A., Olney, R. S., Holmes, L. B., Lin, A. E., Keppler-Noreuil, K. M., & Moore, C. A. (2003). Guidelines for case classification for the National Birth Defects Prevention Study. Birth Defects Research. Part A, Clinical and Molecular Teratology, 67(3), 193–201.
16. Recommendations for the use of folic acid to reduce the number of cases of spina bifida and other neural tube defects. (1992). MMWR Recommendations and Reports, 41(RR-14), 1–7.
17. Reefhuis, J., Gilboa, S. M., Anderka, M., Browne, M. L., Feldkamp, M. L., Hobbs, C. A., … Honein, M. A. (2015). The National Birth Defects Prevention Study: A review of the methods. Birth Defects Research. Part A, Clinical and Molecular Teratology, 103(8), 656–669.
18. Sotres-Alvarez, D., Siega-Riz, A. M., Herring, A. H., Carmichael, S. L., Feldkamp, M. L., Hobbs, C. A., & Olshan, A. F. (2013). Maternal dietary patterns are associated with risk of neural tube and congenital heart defects. American Journal of Epidemiology, 177(11), 1279–1288.
19. Suarez, L., Felkner, M., Brender, J. D., & Canfield, M. A. (2012). Dieting to lose weight and occurrence of neural tube defects in offspring of Mexican-American women. Maternal and Child Health Journal, 16(4), 844–849.
20. Tinker, S. C., Hamner, H. C., Qi, Y. P., & Crider, K. S. (2015). U.S. women of childbearing age who are at possible increased risk of a neural tube defect-affected pregnancy due to suboptimal red blood cell folate concentrations, National Health and Nutrition Examination Survey 2007 to 2012. Birth Defects Research. Part A, Clinical and Molecular Teratology, 103(6), 517–526.
21. Tsang, B. L., Devine, O. J., Cordero, A. M., Marchetta, C. M., Mulinare, J., Mersereau, P., … Hamner, H. C. (2015). Assessing the association between the methylenetetrahydrofolate reductase (MTHFR) 677C>T polymorphism and blood folate concentrations: A systematic review and meta-analysis of trials and observational studies. The American Journal of Clinical Nutrition, 101(6), 1286–1294.
22. USDA Agricultural Research Service. (2007). USDA National Nutrient Database for Standard Reference, Release 20. Washington, DC: Author. Retrieved from http://www.ars.usda.gov/ba/bhnrc/ndl.
23. Willett, W. C., Reynolds, R. D., Cottrell-Hoehner, S., Sampson, L., & Browne, M. L. (1987). Validation of a semi-quantitative food frequency questionnaire: Comparison with a 1-year diet record. Journal of the American Dietetic Association, 87(1), 43–47.
24. Williams, J., Mai, C. T., Mulinare, J., Isenburg, J., Flood, T. J., Ethen, M., … Centers for Disease Control and Prevention. (2015). Updated estimates of neural tube defects prevented by mandatory folic Acid fortification - United States, 1995–2011. MMWR Morbidity and Mortality Weekly Report, 64(1), 1–5.