Predictors of mortality in Middle East respiratory syndrome (MERS)

Thorax

Volumn 73, Issue 3, 2018, Pages 286-289

  Hong, Ki Ho ^a   Choi, Jae Phil ^a   Hong, Seon Hui ^b   Lee, Jeewon ^b   Kwon, Ji Soo ^b,c   Kim, Sun Mi ^c   Park, Se Yoon ^c   Rhee, Ji Young ^d   Kim, Baek Nam ^e   Choi, Hee Jung ^f   Shin, Eui Cheol ^b   Pai, Hyunjoo ^g   Park, Su Hyung ^b   Kim, Sung Han ^c  

^a Seoul Medical Center   (South Korea)

^b Korea Advanced Institute of Science and Technology (KAIST)   (South Korea)

^c University of Ulsan College of Medicine   (South Korea)

^d Dankook University   (South Korea)

^e Inje University College of Medicine   (South Korea)

^f Ewha Womans University   (South Korea)

^g Hanyang University   (South Korea)

Author keywords

infection control; respiratory infection; viral infection

Indexed keywords

ALANINE AMINOTRANSFERASE; ALBUMIN; ALPHA INTERFERON; ASPARTATE AMINOTRANSFERASE; C REACTIVE PROTEIN; HEMOGLOBIN; IMMUNOGLOBULIN; INDUCIBLE PROTEIN 10; INTERLEUKIN 6; LOPINAVIR PLUS RITONAVIR; MONOCYTE CHEMOTACTIC PROTEIN 1; NITROGEN; RIBAVIRIN; STEROID; UNCLASSIFIED DRUG; UREA; CYTOKINE; VIRUS ANTIBODY;

ADULT; AGING; ANTIBODY TITER; ARTICLE; ARTIFICIAL VENTILATION; CHRONIC KIDNEY FAILURE; CHRONIC LUNG DISEASE; CLINICAL ARTICLE; CONTROLLED STUDY; DIABETES MELLITUS; DISEASE COURSE; EXTRACORPOREAL OXYGENATION; FEMALE; HEART DISEASE; HOSPITAL ADMISSION; HUMAN; HYPERTENSION; IMMUNOFLUORESCENCE TEST; LEUKOCYTE COUNT; MALE; MENTAL DEFICIENCY; MIDDLE EAST RESPIRATORY SYNDROME; MORTALITY RATE; OBESITY; PLATELET COUNT; PNEUMONIA; PNEUMONIA SEVERITY INDEX; PREDICTION; PRIORITY JOURNAL; PROSPECTIVE STUDY; RISK FACTOR; SECONDARY INFECTION; SOLID MALIGNANT NEOPLASM; SURVIVOR; VIRUS LOAD; BLOOD; CORONAVIRINAE; CORONAVIRUS INFECTION; GENETICS; MIDDLE AGED; MORTALITY; REAL TIME POLYMERASE CHAIN REACTION; SURVIVAL RATE;

ANTIBODIES, VIRAL; CORONAVIRUS; CORONAVIRUS INFECTIONS; CYTOKINES; FEMALE; HUMANS; MALE; MIDDLE AGED; REAL-TIME POLYMERASE CHAIN REACTION; RISK FACTORS; SURVIVAL RATE; VIRAL LOAD;

EID: 85040688362     PISSN: 00406376     EISSN: 14683296     Source Type: Journal    
DOI: 10.1136/thoraxjnl-2016-209313     Document Type: Article

References (7)

1. Faure E, Poissy J, Goffard A, et al. Distinct immune response in two MERS-CoV-infected patients: Can we go from bench to bedside PLoS One 2014;9:e88716.
2. Min CK, Cheon S, Ha NY, et al. Comparative and kinetic analysis of viral shedding and immunological responses in MERS patients representing a broad spectrum of disease severity. Sci Rep 2016;6:25359.
3. Kumar M, Mazur S, Ork BL, et al. Inactivation and safety testing of Middle East respiratory syndrome coronavirus. J Virol Methods 2015;223:13-18.
4. Huang KJ, Su IJ, Theron M, et al. An interferon-gammarelated cytokine storm in SARS patients. J Med Virol 2005;75:185-94.
5. Jiang Y, Xu J, Zhou C, et al. Characterization of cytokine/chemokine profiles of severe acute respiratory syndrome. Am J Respir Crit Care Med 2005;171:850-7.
6. Wong CK, Lam CW, Wu AK, et al. Plasma inflammatory cytokines and chemokines in severe acute respiratory syndrome. Clin Exp Immunol 2004;136:95-103.
7. Hui DS, Memish ZA, Zumla A. Severe acute respiratory syndrome vs. the Middle East respiratory syndrome. Curr Opin Pulm Med 2014;20:233-41.