Identification of alcohol stress tolerance genes of Synechocystis sp. PCC 6803 using adaptive laboratory evolution

Biotechnology for Biofuels

Volumn 10, Issue 1, 2017, Pages

  Matsusako, Takuya ^a   Toya, Yoshihiro ^a   Yoshikawa, Katsunori ^a   Shimizu, Hiroshi ^a  

^a OSAKA UNIVERSITY   (Japan)

Author keywords

Adaptive laboratory evolution; Alcohol stress tolerance; Isobutanol; Synechocystis sp. PCC 6803

Indexed keywords

ETHANOL;

ACQUIRED RESISTANCE; ADAPTIVE LABORATORY EVOLUTION; ISOBUTANOL; MUTATION ANALYSIS; STRESS RESISTANCE; STRESS TOLERANCE; STRESS-TOLERANCE GENES; SYNECHOCYSTIS SP. PCC 6803;

BIOLOGY;

ALCOHOL; CYANOBACTERIUM; GENETIC ANALYSIS; IDENTIFICATION METHOD; LABORATORY METHOD; MUTATION; STRESS RESISTANCE;

SYNECHOCYSTIS SP. PCC 6803;

EID: 85038935697     PISSN: 17546834     EISSN: None     Source Type: Journal    
DOI: 10.1186/s13068-017-0996-5     Document Type: Article

References (33)

1. Dexter J, Armshaw P, Sheahan C, Pembroke JT. The state of autotrophic ethanol production in Cyanobacteria. J Appl Microbiol. 2015;119:11-24.
2. Atsumi S, Higashide W, Liao JC. Direct photosynthetic recycling of carbon dioxide to isobutyraldehyde. Nat Biotechnol. 2009;27:1177-80.
3. Smith KM, Liao JC. An evolutionary strategy for isobutanol production strain development in Escherichia coli. Metab Eng. 2011;13:674-81.
4. Yamamoto S, Suda M, Niimi S, Inui M, Yukawa H. Strain optimization for efficient isobutanol production using Corynebacterium glutamicum under oxygen deprivation. Biotechnol Bioeng. 2013;110:2938-48.
5. Varman AM, Xiao Y, Pakrasi HB, Tang YJ. Metabolic engineering of Synechocystis sp. strain PCC 6803 for isobutanol production. Appl Environ Microbiol. 2013;79:908-14.
6. Anfelt J, Hallström B, Nielsen J, Uhlén M, Hudson EP. Using transcriptomics to improve butanol tolerance of Synechocystis sp. strain PCC 6803. Appl Environ Microbiol. 2013;79:7419-27.
7. Chen L, Wu L, Wang J, Zhang W. Butanol tolerance regulated by a two-component response regulator Slr 1037 in photosynthetic Synechocystis sp. PCC 6803. Biotechnol Biofuels. 2014;7:89.
8. Niu X, Zhu Y, Pei G, Wu L, Chen L, Zhang W. Elucidating butanol tolerance mediated by a response regulator Sll0039 in Synechocystis sp. PCC 6803 using a metabolomic approach. Appl Microbiol Biotechnol. 2015;99(4):1845-57.
9. Gao X, Sun T, Wu L, Chen L, Zhang W. Co-overexpression of response regulator genes slr1037 and sll0039 improves tolerance of Synechocystis sp. PCC 6803 to 1-butanol. Bioresour Technol. 2017;245(Pt B):1476-83.
10. Kaczmarzyk D, Anfelt J, Särnegrim A, Hudson EP. Overexpression of sigma factor SigB improves temperature and butanol tolerance of Synechocystis sp. PCC6803. J Biotechnol. 2014;182-183:54-60.
11. Sandberg TE, Pedersen M, LaCroix RA, Ebrahim A, Bonde M, Herrgard MJ, Palsson BØ, Sommer M, Feist AM. Evolution of Escherichia coli to 42°C and subsequent genetic engineering reveals adaptive mechanisms and novel mutations. Mol Biol Evol. 2014;31:2647-62.
12. LaCroix RA, Sandberg TE, O'Brien EJ, Utrilla J, Ebrahim A, Guzman GI, Szubin R, Palsson BØ, Feist AM. Use of adaptive laboratory evolution to discover key mutations enabling rapid growth of Escherichia coli K-12 MG1655 on glucose minimal medium. Appl Environ Microbiol. 2015;81:17-30.
13. Dragosits M, Mattanovich D. Adaptive laboratory evolution - principles and applications for biotechnology. Microb Cell Fact. 2013;12:64.
14. Lee DH, Feist AM, Barrett CL, Palsson BØ. Cumulative number of cell divisions as a meaningful timescale for adaptive laboratory evolution of Escherichia coli. PLoS ONE. 2011;6:e26172.
15. Kaneko T, Sato S, Kotani H, Tanaka A, Asamizu E, Nakamura Y, Miyajima N, Hirosawa M, Sugiura M, Sasamoto S, Kimura T, Hosouchi T, Matsuno A, Muraki A, Nakazaki N, Naruo K, Okumura S, Shimpo S, Takeuchi C, Wada T, Watanabe A, Yamada M, Yasuda M, Tabata S. Sequence analysis of the genome of the unicellular cyanobacterium Synechocystis sp. strain PCC6803. II. Sequence determination of the entire genome and assignment of potential protein-coding regions. DNA Res. 1996;3:109-36.
16. Kanesaki Y, Shiwa Y, Tajima N, Suzuki M, Watanabe S, Sato N, Ikeuchi M, Yoshikawa H. Identification of substrain-specific mutations by massively parallel whole-genome resequencing of Synechocystis sp. PCC 6803. DNA Res. 2012;19:67-79.
17. Uchiyama J, Kanesaki Y, Iwata N, Asakura R, Funamizu K, Tasaki R, Agatsuma M, Tahara H, Matsuhashi A, Yoshikawa H, Ogawa S, Ohta H. Genomic analysis of parallel-evolved cyanobacterium Synechocystis sp. PCC 6803 under acid stress. Photosynth Res. 2015;125:243-54.
18. Atsumi S, Wu TY, Machado IM, Huang WC, Chen PY, Pellegrini M, Liao JC. Evolution, genomic analysis, and reconstruction of isobutanol tolerance in Escherichia coli. Mol Syst Biol. 2010;6:449.
19. Suzuki S, Horinouchi T, Furusawa C. Prediction of antibiotic resistance by gene expression profiles. Nat Commun. 2014;5:5792.
20. Yoshihara S, Geng X. Ikeuchi M. pilG gene cluster and split pilL genes involved in pilus biogenesis, motility and genetic transformation in the cyanobacterium Synechocystis sp. PCC 6803. Plant Cell Physiol. 2002;43:513-21.
21. Pisareva T, Shumskaya M, Maddalo G, Ilag L, Norling B. Proteomics of Synechocystis sp. PCC 6803. Identification of novel integral plasma membrane proteins. FEBS J. 2007;274:791-804.
22. Tian X, Chen L, Wang J, Qiao J, Zhang W. Quantitative proteomics reveals dynamic responses of Synechocystis sp. PCC 6803 to next-generation biofuel butanol. J Proteom. 2013;78:326-45.
23. Lei J, Zhao X, Ge X, Bai F. Ethanol tolerance and the variation of plasma membrane composition of yeast floc populations with different size distribution. J Biotechnol. 2007;131:270-5.
24. Cheng C, Zhang M, Xue C, Bai F, Zhao X. Development of stress tolerant Saccharomyces cerevisiae strains by metabolic engineering: new aspects from cell flocculation and zinc supplementation. J Biosci Bioeng. 2017;123:141-6.
25. Sasaki NV, Sato N. CyanoClust: comparative genome resources of cyanobacteria and plastids. Database (Oxford). 2010;2010:bap025.
26. Du D, Wang Z, James NR, Voss JE, Klimont E, Ohene-Agyei T, Venter H, Chiu W, Luisi BF. Structure of the AcrAB-TolC multidrug efflux pump. Nature. 2014;509:512-5.
27. Mukhopadhyay A. Tolerance engineering in bacteria for the production of advanced biofuels and chemicals. Trends Microbiol. 2015;23:498-508.
28. Brynildsen MP, Liao JC. An integrated network approach identifies the isobutanol response network of Escherichia coli. Mol Syst Biol. 2009;5:277.
29. Shyu JB, Lies DP, Newman DK. Protective role of tolC in efflux of the electron shuttle anthraquinone-2,6-disulfonate. J Bacteriol. 2002;184:1806-10.
30. Yoshikawa K, Hirasawa T, Ogawa K, Hidaka Y, Nakajima T, Furusawa C, Shimizu H. Integrated transcriptomic and metabolomic analysis of the central metabolism of Synechocystis sp. PCC 6803 under different trophic conditions. Biotechnol J. 2013;8:571-80.
31. Yoshikawa K, Hirasawa T, Shimizu H. Effect of malic enzyme on ethanol production by Synechocystis sp. PCC 6803. J Biosci Bioeng. 2015;119:82-4.
32. Langmead B, Salzberg SL. Fast gapped-read alignment with Bowtie 2. Nat Methods. 2012;9:357-9.
33. Robinson JT, Thorvaldsdóttir H, Winckler W, Guttman M, Lander ES, Getz G, Mesirov JP. Integrative genomics viewer. Nat Biotechnol. 2011;29:24-6.