LncRNA PLAC2 down-regulates RPL36 expression and blocks cell cycle progression in glioma through a mechanism involving STAT1

Journal of Cellular and Molecular Medicine

Volumn 22, Issue 1, 2018, Pages 497-510

  Hu, Yan Wei ^a   Kang, Chun Min ^a   Zhao, Jing Jing ^a   Nie, Ying ^b   Zheng, Lei ^a   Li, Hai Xia ^a   Li, Xin ^a   Wang, Qian ^a   Qiu, Yu Rong ^a  

^a SOUTHERN MEDICAL UNIVERSITY   (China)

^b Guangdong 999 Brain Hospital   (China)

Author keywords

cell cycle; glioma; lncRNA PLAC2; RPL36; STAT1

Indexed keywords

LENTIVIRUS VECTOR; LONG UNTRANSLATED RNA; RIBOSOME PROTEIN; SMALL INTERFERING RNA; STAT1 PROTEIN; RPL36A PROTEIN, HUMAN; STAT1 PROTEIN, HUMAN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CARCINOGENICITY; CELL CYCLE ARREST; CELL CYCLE PROGRESSION; CELL FRACTIONATION; CELL INVASION ASSAY; CELL PROLIFERATION; CELL PROLIFERATION ASSAY; CHROMATIN; CHROMATIN IMMUNOPRECIPITATION; DOWN REGULATION; FEMALE; FLOW CYTOMETRY; FLUORESCENCE IN SITU HYBRIDIZATION; GENE EXPRESSION; GENE EXPRESSION REGULATION; GENE OVEREXPRESSION; GENETIC TRANSFECTION; GLIOMA; GROWTH INHIBITION; IMMUNOHISTOCHEMISTRY; IMMUNOPRECIPITATION; LENTIVIRINAE; LUCIFERASE ASSAY; MALE; MASS SPECTROMETRY; MICROARRAY ANALYSIS; MOUSE; NONHUMAN; PLASMID; PRIORITY JOURNAL; PROTEIN INTERACTION; REAL TIME POLYMERASE CHAIN REACTION; RNA ISOLATION; RNA PURIFICATION; TUMOR GROWTH; UPREGULATION; WESTERN BLOTTING; ADULT; ANIMAL; BAGG ALBINO MOUSE; BIOLOGICAL MODEL; CELL CYCLE; CELL CYCLE CHECKPOINT; CELL CYCLE G1 PHASE; CELL CYCLE S PHASE; GENETICS; HUMAN; METABOLISM; NUDE MOUSE; PATHOLOGY; TUMOR CELL LINE;

ADULT; ANIMALS; CELL CYCLE; CELL CYCLE CHECKPOINTS; CELL LINE, TUMOR; CELL PROLIFERATION; DOWN-REGULATION; FEMALE; G1 PHASE; GENE EXPRESSION REGULATION, NEOPLASTIC; GLIOMA; HUMANS; MALE; MICE, INBRED BALB C; MICE, NUDE; MODELS, BIOLOGICAL; RIBOSOMAL PROTEINS; RNA, LONG NONCODING; S PHASE; STAT1 TRANSCRIPTION FACTOR;

EID: 85038916273     PISSN: 15821838     EISSN: None     Source Type: Journal    
DOI: 10.1111/jcmm.13338     Document Type: Article

References (51)

1. Morgan LL. The epidemiology of glioma in adults: a “state of the science” review. Neuro-oncology. 2015; 17: 623–624.
2. Bao S, Wu Q, McLendon RE, et al. Glioma stem cells promote radioresistance by preferential activation of the DNA damage response. Nature. 2006; 444: 756–760.
3. Ostrom QT, Gittleman H, Stetson L, et al. Epidemiology of gliomas. Cancer Treat Res. 2015; 163: 1–14.
4. Singh SK, Clarke ID, Terasaki M, et al. Identification of a cancer stem cell in human brain tumors. Can Res. 2003; 63: 5821–5828.
5. Rosen ST. Current understanding and treatment of glioma. In: Raizer J, Parsa A, editor. Cancer Treatment and Research. Springer: Duarte, CA, USA; 2015, 163. pp. 1–14.
6. Anderson DM, Anderson KM, Chang CL, et al. A micropeptide encoded by a putative long noncoding RNA regulates muscle performance. Cell. 2015; 160: 595–606.
7. Ranzani V, Rossetti G, Panzeri I, et al. The long intergenic noncoding RNA landscape of human lymphocytes highlights the regulation of T cell differentiation by linc-MAF-4. Nat Immunol. 2015; 16: 318–325.
8. Savic N, Bar D, Leone S, et al. lncRNA maturation to initiate heterochromatin formation in the nucleolus is required for exit from pluripotency in ESCs. Cell Stem Cell. 2014; 15: 720–734.
9. Patel JS, Hu M, Sinha G, et al. Non-coding RNA as mediators in microenvironment-breast cancer cell communication. Cancer Lett. 2015; 380: 289–95.
10. Zheng S, Chen H, Wang Y, et al. Long non-coding RNA LOC389641 promotes progression of pancreatic ductal adenocarcinoma and increases cell invasion by regulating E-cadherin in a TNFRSF10A-related manner. Cancer Lett. 2015; 371: 354–65.
11. Kang CM, Hu YW, Nie Y, et al. Long non-coding RNA RP5-833A20.1 inhibits proliferation, metastasis and cell cycle progression by suppressing the expression of NFIA in U251 cells. Mol Med Rep. 2016; 14: 5288–5296.
12. Wapinski O, Chang HY. Long noncoding RNAs and human disease. Trends Cell Biol. 2011; 21: 354–361.
13. Wilson DN, Doudna Cate JH. The structure and function of the eukaryotic ribosome. Cold Spring Harb Perspect Biol. 2012; 4: 1–17.
14. Zhang Y, Berger SA. Increased calcium influx and ribosomal content correlate with resistance to endoplasmic reticulum stress-induced cell death in mutant leukemia cell lines. J Biol Chem. 2004; 279: 6507–6516.
15. Yao Y, Liu Y, Lv X, et al. Down-regulation of ribosomal protein S15A inhibits proliferation of human glioblastoma cells in vivo and in vitro via AKT pathway. Tumour Biol. 2016; 37: 4979–4990.
16. Yong WH, Shabihkhani M, Telesca D, et al. Ribosomal proteins RPS11 and RPS20, two stress-response markers of glioblastoma stem cells, are novel predictors of poor prognosis in glioblastoma patients. PLoS ONE. 2015; 10: e0141334.
17. Song MJ, Jung CK, Park CH, et al. RPL36 as a prognostic marker in hepatocellular carcinoma. Pathol Int. 2011; 61: 638–644.
18. Tian X, Sun D, Zhao S, et al. Screening of potential diagnostic markers and therapeutic targets against colorectal cancer. Onco Targets Ther. 2015; 8: 1691–1699.
19. Provost E, Bailey JM, Aldrugh S, et al. The tumor suppressor rpl36 restrains KRAS(G12V)-induced pancreatic cancer. Zebrafish. 2014; 11: 551–559.
20. Hu YW, Zhao JY, Li SF, et al. RP5-833A20.1/miR-382-5p/NFIA-dependent signal transduction pathway contributes to the regulation of cholesterol homeostasis and inflammatory reaction. Arterioscler Thromb Vasc Biol. 2015; 35: 87–101.
21. Chu C, Qu K, Zhong FL, et al. Genomic maps of long noncoding RNA occupancy reveal principles of RNA-chromatin interactions. Mol Cell. 2011; 44: 667–678.
22. Chu C, Quinn J, Chang HY. Chromatin isolation by RNA purification (ChIRP). J Vis Exp. 2012; 61: 1–6.
23. Chu C, Zhang QC, da Rocha ST, et al. Systematic discovery of Xist RNA binding proteins. Cell. 2015; 161: 404–416.
24. Rapicavoli NA, Qu K, Zhang J, et al. A mammalian pseudogene lncRNA at the interface of inflammation and anti-inflammatory therapeutics. Elife. 2013; 2: e00762.
25. Li L, Matsui M, Corey DR. Activating frataxin expression by repeat-targeted nucleic acids. Nat Commun. 2016; 7: 10606.
26. Zhang JX, Han L, Bao ZS, et al. HOTAIR, a cell cycle-associated long noncoding RNA and a strong predictor of survival, is preferentially expressed in classical and mesenchymal glioma. Neuro-oncology. 2013; 15: 1595–1603.
27. Nie FQ, Sun M, Yang JS, et al. Long noncoding RNA ANRIL promotes non-small cell lung cancer cell proliferation and inhibits apoptosis by silencing KLF2 and P21 expression. Mol Cancer Ther. 2015; 14: 268–277.
28. Malumbres M, Barbacid M. Cell cycle, CDKs and cancer: a changing paradigm. Nat Rev Cancer. 2009; 9: 153–166.
29. Rossetto CC, Tarrant-Elorza M, Verma S, et al. Regulation of viral and cellular gene expression by Kaposi's sarcoma-associated herpesvirus polyadenylated nuclear RNA. J Virol. 2013; 87: 5540–5553.
30. Messeguer X, Escudero R, Farre D, et al. PROMO: detection of known transcription regulatory elements using species-tailored searches. Bioinformatics. 2002; 18: 333–334.
31. Ostrom QT, Gittleman H, Farah P, et al. CBTRUS statistical report: primary brain and central nervous system tumors diagnosed in the United States in 2006–2010. Neuro-oncology. 2013; 15(Suppl. 2): ii1–ii56.
32. Torre LA, Bray F, Siegel RL, et al. Global cancer statistics, 2012. CA Cancer J Clin. 2015; 65: 87–108.
33. Prensner JR, Chinnaiyan AM. The emergence of lncRNAs in cancer biology. Cancer Discov. 2011; 1: 391–407.
34. Gibb EA, Vucic EA, Enfield KSS, et al. Human cancer long non-coding RNA transcriptomes. PLoS ONE. 2011; 6: 1–10.
35. Wang R, Shi Y, Chen L, et al. The ratio of FoxA1 to FoxA2 in lung adenocarcinoma is regulated by LncRNA HOTAIR and chromatin remodeling factor LSH. Sci Rep. 2015; 5: 17826.
36. Gutschner T, Hammerle M, Eissmann M, et al. The noncoding RNA MALAT1 Is a critical regulator of the metastasis phenotype of lung cancer cells. Can Res. 2013; 73: 1180–1189.
37. Yuan JH, Yang F, Wang F, et al. A long noncoding RNA activated by TGF-beta promotes the invasion-metastasis cascade in hepatocellular carcinoma. Cancer Cell. 2014; 25: 666–681.
38. Wang Y, Wang Y, Li J, et al. CRNDE, a long-noncoding RNA, promotes glioma cell growth and invasion through mTOR signaling. Cancer Lett. 2015; 367: 122–128.
39. Ma KX, Wang HJ, Li XR, et al. Long noncoding RNA MALAT1 associates with the malignant status and poor prognosis in glioma. Tumour Biol. 2015; 36: 3355–3359.
40. Melo CA, Drost J, Wijchers PJ, et al. eRNAs are required for p53-dependent enhancer activity and gene transcription. Mol Cell. 2013; 49: 524–535.
41. Petruk S, Sedkov Y, Riley KM, et al. Transcription of bxd noncoding RNAs promoted by trithorax represses Ubx in cis by transcriptional interference. Cell. 2006; 127: 1209–1221.
42. Zhao J, Sun BK, Erwin JA, et al. Polycomb proteins targeted by a short repeat RNA to the mouse X chromosome. Science. 2008; 322: 750–756.
43. Selman C, Tullet JM, Wieser D, et al. Ribosomal protein S6 kinase 1 signaling regulates mammalian life span. Science. 2009; 326: 140–144.
44. Volarevic S, Stewart MJ, Ledermann B, et al. Proliferation, but not growth, blocked by conditional deletion of 40S ribosomal protein S6. Science. 2000; 288: 2045–2047.
45. Shen D-W, Liang X-J, Suzuki T, et al. Identification by functional cloning from a retroviral cDNA library of cDNAs for ribosomal protein L36 and heat shock protein 10 that confer cisplatin resistance. Mol Pharmacol. 2006; 69: 1383–1388.
46. Peng C, Zeng W, Su J, et al. Cyclin-dependent kinase 2 (CDK2) is a key mediator for EGF-induced cell transformation mediated through the ELK4/c-Fos signaling pathway. Oncogene. 2015; 35: 1170–9.
47. Zhang D, Chen HP, Duan HF, et al. Aggregation of ribosomal protein S6 at nucleolus is cell cycle-controlled and its function in pre-rRNA processing is phosphorylation dependent. J Cell Biochem. 2016; 117: 1649–1657.
48. Maruyama Y, Miyazaki T, Ikeda K, et al. Short hairpin RNA library-based functional screening identified ribosomal protein L31 that modulates prostate cancer cell growth via p53 pathway. PLoS ONE. 2014; 9: e108743.
49. He G, Siddik ZH, Huang Z, et al. Induction of p21 by p53 following DNA damage inhibits both Cdk4 and Cdk2 activities. Oncogene. 2005; 24: 2929–2943.
50. Wang J, Liu X, Wu H, et al. CREB up-regulates long non-coding RNA, HULC expression through interaction with microRNA-372 in liver cancer. Nucleic Acids Res. 2010; 38: 5366–5383.
51. Tripathi V, Ellis JD, Shen Z, et al. The nuclear-retained noncoding RNA MALAT1 regulates alternative splicing by modulating SR splicing factor phosphorylation. Mol Cell. 2010; 39: 925–938.