Effect of PCSK9 inhibitors on clinical outcomes in patients with hypercholesterolemia: A meta-analysis of 35 randomized controlled trials

Journal of the American Heart Association

Volumn 6, Issue 12, 2017, Pages

  Karatasakis, Aris ^a,b   Danek, Barbara A ^a,b   Karacsonyi, Judit ^a   Rangan, Bavana V ^a   Roesle, Michele K ^a   Knickelbine, Thomas ^c   Miedema, Michael D ^c   Khalili, Houman ^a   Ahmad, Zahid ^a   Abdullah, Shuaib ^a   Banerjee, Subhash ^a   Brilakis, Emmanouil S ^a,c  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^b RUTGERS NEW JERSEY MEDICAL SCHOOL   (United States)

^c MINNEAPOLIS HEART INSTITUTE FOUNDATION   (United States)

Author keywords

Alirocumab; Evolocumab; Hyperlipidemia; Outcome; PCSK9

Indexed keywords

ALANINE AMINOTRANSFERASE; ALIROCUMAB; ASPARTATE AMINOTRANSFERASE; CREATINE KINASE; EVOLOCUMAB; LOW DENSITY LIPOPROTEIN CHOLESTEROL; HYPOCHOLESTEROLEMIC AGENT; MONOCLONAL ANTIBODY; PCSK9 PROTEIN, HUMAN; PROPROTEIN CONVERTASE 9;

AGE; ALL CAUSE MORTALITY; CARDIOVASCULAR MORTALITY; CEREBROVASCULAR ACCIDENT; CLINICAL OUTCOME; DIABETES MELLITUS; DISORDERS OF HIGHER CEREBRAL FUNCTION; DRUG EFFICACY; DRUG SAFETY; FOLLOW UP; HEART INFARCTION; HEART MUSCLE REVASCULARIZATION; HUMAN; HYPERCHOLESTEROLEMIA; HYPERTRANSAMINASEMIA; META ANALYSIS; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL (TOPIC); REVIEW; SIDE EFFECT; SYSTEMATIC REVIEW; ANTAGONISTS AND INHIBITORS; BLOOD; TREATMENT OUTCOME;

ANTIBODIES, MONOCLONAL; ANTICHOLESTEREMIC AGENTS; HUMANS; HYPERCHOLESTEROLEMIA; PROPROTEIN CONVERTASE 9; RANDOMIZED CONTROLLED TRIALS AS TOPIC; TREATMENT OUTCOME;

EID: 85038866681     PISSN: None     EISSN: 20479980     Source Type: Journal    
DOI: 10.1161/JAHA.117.006910     Document Type: Review

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