메뉴 건너뛰기




Volumn 318, Issue 22, 2017, Pages 2211-2223

Development and validation of a deep learning system for diabetic retinopathy and related eye diseases using retinal images from multiethnic populations with diabetes

(29)  Ting, Daniel Shu Wei a,b   Cheung, Carol Yim Lui a,c   Lim, Gilbert b   Tan, Gavin Siew Wei a,b   Quang, Nguyen D a   Gan, Alfred a   Hamzah, Haslina a   Garcia Franco, Renata d   Yeo, Ian Yew San a,b   Lee, Shu Yen a,b   Wong, Edmund Yick Mun a,b   Sabanayagam, Charumathi a,b   Baskaran, Mani a,b   Ibrahim, Farah b   Tan, Ngiap Chuan b,e   Finkelstein, Eric A f   Lamoureux, Ecosse L a,b   Wong, Ian Y g   Bressler, Neil M h   Sivaprasad, Sobha i   more..


Author keywords

[No Author keywords available]

Indexed keywords

ACCREDITATION; ADULT; AGE RELATED MACULAR DEGENERATION; AREA UNDER THE CURVE; ARTICLE; COHORT ANALYSIS; CONTROLLED STUDY; DEEP LEARNING SYSTEM; DIABETIC RETINOPATHY; DIAGNOSTIC PROCEDURE; DIAGNOSTIC TEST ACCURACY STUDY; DISEASE SEVERITY; FEMALE; GLAUCOMA; HUMAN; MACHINE LEARNING; MAJOR CLINICAL STUDY; MALE; OPHTHALMOLOGIST; OPTOMETRIST; PRIORITY JOURNAL; RETINA EXAMINATION; RETINA IMAGE; SENSITIVITY AND SPECIFICITY; STANDARD; VALIDATION PROCESS; COMPARATIVE STUDY; DIABETES MELLITUS; DIAGNOSTIC IMAGING; ETHNOLOGY; EYE DISEASE; INFORMATION PROCESSING; MIDDLE AGED; PATHOLOGY; RECEIVER OPERATING CHARACTERISTIC; RETINA; VALIDATION STUDY;

EID: 85038438910     PISSN: 00987484     EISSN: 15383598     Source Type: Journal    
DOI: 10.1001/jama.2017.18152     Document Type: Article
Times cited : (1635)

References (40)
  • 1
    • 84859030420 scopus 로고    scopus 로고
    • Global prevalence and major risk factors of diabetic retinopathy
    • Yau JW, Rogers SL, Kawasaki R, et al.; Meta-Analysis for Eye Disease (META-EYE) Study Group. Global prevalence and major risk factors of diabetic retinopathy. Diabetes Care. 2012; 35(3): 556-564.
    • (2012) Diabetes Care , vol.35 , Issue.3 , pp. 556-564
    • Yau, J.W.1    Rogers, S.L.2    Kawasaki, R.3
  • 2
    • 84974782886 scopus 로고    scopus 로고
    • Diabetic retinopathy: Global prevalence, major risk factors, screening practices and public health challenges: A review
    • Ting DS, Cheung GC, Wong TY. Diabetic retinopathy: global prevalence, major risk factors, screening practices and public health challenges: a review. Clin Exp Ophthalmol. 2016; 44(4):260-277.
    • (2016) Clin Exp Ophthalmol. , vol.44 , Issue.4 , pp. 260-277
    • Ting, D.S.1    Cheung, G.C.2    Wong, T.Y.3
  • 3
    • 77955013602 scopus 로고    scopus 로고
    • Diabetic retinopathy
    • Cheung N, Mitchell P, Wong TY. Diabetic retinopathy. Lancet. 2010; 376(9735):124-136.
    • (2010) Lancet , vol.376 , Issue.9735 , pp. 124-136
    • Cheung, N.1    Mitchell, P.2    Wong, T.Y.3
  • 4
    • 85023162381 scopus 로고    scopus 로고
    • Availability and variability in guidelines on diabetic retinopathy screening in Asian countries
    • Wang LZ, Cheung CY, Tapp RJ, et al. Availability and variability in guidelines on diabetic retinopathy screening in Asian countries. Br J Ophthalmol. 2017; 101(10):1352-1360.
    • (2017) Br J Ophthalmol. , vol.101 , Issue.10 , pp. 1352-1360
    • Wang, L.Z.1    Cheung, C.Y.2    Tapp, R.J.3
  • 5
    • 84879800827 scopus 로고    scopus 로고
    • Diabetic retinopathy in sub-saharan Africa: Meeting the challengesofanemerging epidemic
    • Burgess PI, Msukwa G, Beare NA. Diabetic retinopathy in sub-Saharan Africa: meeting the challengesofanemerging epidemic. BMC Med. 2013; 11:157.
    • (2013) BMC Med. , vol.11 , pp. 157
    • Burgess, P.I.1    Msukwa, G.2    Beare, N.A.3
  • 6
    • 80054983115 scopus 로고    scopus 로고
    • Revisiting diabetes 2000: Challenges in establishing nationwide diabetic retinopathy prevention programs
    • Hazin R, Colyer M, Lum F, Barazi MK. Revisiting Diabetes 2000: challenges in establishing nationwide diabetic retinopathy prevention programs. Am J Ophthalmol. 2011; 152(5):723-729.
    • (2011) Am J Ophthalmol. , vol.152 , Issue.5 , pp. 723-729
    • Hazin, R.1    Colyer, M.2    Lum, F.3    Barazi, M.K.4
  • 7
    • 79954466772 scopus 로고    scopus 로고
    • Diabetic retinopathy managementbyAustralian optometrists
    • Ting DS, Ng JQ, Morlet N, et al. Diabetic retinopathy managementbyAustralian optometrists. Clin Exp Ophthalmol. 2011; 39(3):230-235.
    • (2011) Clin Exp Ophthalmol. , vol.39 , Issue.3 , pp. 230-235
    • Ting, D.S.1    Ng, J.Q.2    Morlet, N.3
  • 8
    • 84930630277 scopus 로고    scopus 로고
    • Deep learning
    • LeCun Y, Bengio Y, Hinton G. Deep learning. Nature. 2015; 521(7553):436-444.
    • (2015) Nature , vol.521 , Issue.7553 , pp. 436-444
    • LeCun, Y.1    Bengio, Y.2    Hinton, G.3
  • 10
    • 85007529863 scopus 로고    scopus 로고
    • Development and validation of a deep learning algorithm for detection of diabetic retinopathy in retinal fundus photographs
    • Gulshan V, Peng L, Coram M, et al. Development and validation of a deep learning algorithm for detection of diabetic retinopathy in retinal fundus photographs. JAMA. 2016; 316(22): 2402-2410.
    • (2016) JAMA , vol.316 , Issue.22 , pp. 2402-2410
    • Gulshan, V.1    Peng, L.2    Coram, M.3
  • 11
    • 85016221341 scopus 로고    scopus 로고
    • Automated identification of diabetic retinopathy using deep learning
    • Gargeya R, Leng T. Automated identification of diabetic retinopathy using deep learning. Ophthalmology. 2017; 124(7):962-969.
    • (2017) Ophthalmology , vol.124 , Issue.7 , pp. 962-969
    • Gargeya, R.1    Leng, T.2
  • 12
    • 84990193991 scopus 로고    scopus 로고
    • Improved automated detection of diabetic retinopathy on a publicly available dataset through integration of deep learning
    • Abràmoff MD, Lou Y, Erginay A, et al. Improved automated detection of diabetic retinopathy on a publicly available dataset through integration of deep learning. Invest Ophthalmol Vis Sci. 2016; 57 (13):5200-5206.
    • (2016) Invest Ophthalmol Vis Sci. , vol.57 , Issue.13 , pp. 5200-5206
    • Abràmoff, M.D.1    Lou, Y.2    Erginay, A.3
  • 13
    • 85007597269 scopus 로고    scopus 로고
    • Artificial intelligence with deep learning technology looks into diabetic retinopathy screening
    • Wong TY, Bressler NM. Artificial intelligence with deep learning technology looks into diabetic retinopathy screening. JAMA. 2016; 316(22):2366-2367.
    • (2016) JAMA , vol.316 , Issue.22 , pp. 2366-2367
    • Wong, T.Y.1    Bressler, N.M.2
  • 14
    • 77949393746 scopus 로고    scopus 로고
    • Automated detection of diabetic retinopathy: Barriers to translation into clinical practice
    • Abramoff MD, Niemeijer M, Russell SR. Automated detection of diabetic retinopathy: barriers to translation into clinical practice. Expert Rev Med Devices. 2010; 7(2):287-296.
    • (2010) Expert Rev Med Devices , vol.7 , Issue.2 , pp. 287-296
    • Abramoff, M.D.1    Niemeijer, M.2    Russell, S.R.3
  • 15
    • 84955312058 scopus 로고    scopus 로고
    • Should we add screening of age-related macular degeneration to current screening programs for diabetic retinopathy?
    • Chew EY, Schachat AP. Should we add screening of age-related macular degeneration to current screening programs for diabetic retinopathy? Ophthalmology. 2015; 122(11):2155-2156.
    • (2015) Ophthalmology , vol.122 , Issue.11 , pp. 2155-2156
    • Chew, E.Y.1    Schachat, A.P.2
  • 16
    • 84992365152 scopus 로고    scopus 로고
    • Cost-effectiveness of a national telemedicine diabetic retinopathy screening program in Singapore
    • Nguyen HV, Tan GS, Tapp RJ, et al. Cost-effectiveness of a national telemedicine diabetic retinopathy screening program in singapore. Ophthalmology. 2016; 123(12):2571-2580.
    • (2016) Ophthalmology , vol.123 , Issue.12 , pp. 2571-2580
    • Nguyen, H.V.1    Tan, G.S.2    Tapp, R.J.3
  • 17
    • 84948747579 scopus 로고    scopus 로고
    • Prevalence and determinants of undiagnosed diabetic retinopathy and vision-threatening retinopathy in a multiethnic Asian cohort: The Singapore epidemiology of eye diseases (SEED) study
    • Huang OS, Tay WT, Ong PG, et al. Prevalence and determinants of undiagnosed diabetic retinopathy and vision-threatening retinopathy in a multiethnic Asian cohort: the Singapore Epidemiology of Eye Diseases (SEED) study. Br J Oph thalmol. 2015; 99(12):1614-1621.
    • (2015) Br J Oph Thalmol. , vol.99 , Issue.12 , pp. 1614-1621
    • Huang, O.S.1    Tay, W.T.2    Ong, P.G.3
  • 18
    • 54949113960 scopus 로고    scopus 로고
    • Prevalence and riskfactors for diabetic retinopathy: The Singapore Malay eye study
    • Wong TY, Cheung N, Tay WT, et al. Prevalence and riskfactors for diabetic retinopathy: the Singapore Malay Eye Study. Ophthalmology. 2008; 115(11):1869-1875.
    • (2008) Ophthalmology , vol.115 , Issue.11 , pp. 1869-1875
    • Wong, T.Y.1    Cheung, N.2    Tay, W.T.3
  • 19
    • 85018263316 scopus 로고    scopus 로고
    • Is aspirin associated with diabetic retinopathy? The Singapore epidemiology of eye disease (SEED) study
    • Shi Y, Tham YC, Cheung N, et al. Is aspirin associated with diabetic retinopathy? the Singapore Epidemiology of Eye Disease (SEED) study. PLoS One. 2017; 12(4):e0175966.
    • (2017) PLoS One , vol.12 , Issue.4 , pp. e0175966
    • Shi, Y.1    Tham, Y.C.2    Cheung, N.3
  • 20
    • 85009275319 scopus 로고    scopus 로고
    • Type 2 diabetes genetic variants and risk of diabetic retinopathy
    • Chong YH, Fan Q, Tham YC, et al. Type 2 diabetes genetic variants and risk of diabetic retinopathy. Ophthalmology. 2017; 124(3):336-342.
    • (2017) Ophthalmology , vol.124 , Issue.3 , pp. 336-342
    • Chong, Y.H.1    Fan, Q.2    Tham, Y.C.3
  • 22
    • 85038423644 scopus 로고    scopus 로고
    • National Institutes of Health website Accessed September 25, 2017
    • Varma R. African American Eye Disease Study. National Institutes of Health website. http://grantome.com/grant/NIH/U10-EY023575-03.2017. Accessed September 25, 2017
    • African American Eye Disease Study
    • Varma, R.1
  • 23
    • 84856657885 scopus 로고    scopus 로고
    • Methodology and early findings of the diabetes management project: A cohort study investigating the Barriers to optimal diabetes care in diabetic patients with and without diabetic retinopathy
    • Lamoureux EL, Fenwick E, Xie J, et al. Methodology and early findings of the Diabetes Management Project: a cohort study investigating the barriers to optimal diabetes care in diabetic patients with and without diabetic retinopathy. Clin Exp Ophthalmol. 2012; 40(1):73-82.
    • (2012) Clin Exp Ophthalmol. , vol.40 , Issue.1 , pp. 73-82
    • Lamoureux, E.L.1    Fenwick, E.2    Xie, J.3
  • 24
    • 85019983592 scopus 로고    scopus 로고
    • Determinants of quantitative optical coherence tomography angiography metrics in patients with diabetes
    • Tang FY, Ng DS, Lam A, et al. Determinants of quantitative optical coherence tomography angiography metrics in patients with diabetes. Sci Rep. 2017; 7(1):2575.
    • (2017) Sci Rep. , vol.7 , Issue.1 , pp. 2575
    • Tang, F.Y.1    Ng, D.S.2    Lam, A.3
  • 25
    • 84939487291 scopus 로고    scopus 로고
    • Prevalence, risk factors, and visual features of undiagnosed glaucoma: The Singapore epidemiology of eye diseases study
    • Chua J, Baskaran M, Ong PG, et al. Prevalence, risk factors, and visual features of undiagnosed glaucoma: the Singapore Epidemiology of Eye Diseases study. JAMA Ophthalmol. 2015; 133(8): 938-946.
    • (2015) JAMA Ophthalmol. , vol.133 , Issue.8 , pp. 938-946
    • Chua, J.1    Baskaran, M.2    Ong, P.G.3
  • 26
    • 84905502262 scopus 로고    scopus 로고
    • Prevalence, racial variations, and risk factors of age-related macular degeneration in Singaporean Chinese, Indians, and Malays
    • Cheung CM, Li X, Cheng CY, et al. Prevalence, racial variations, and risk factors of age-related macular degeneration in Singaporean Chinese, Indians, and Malays. Ophthalmology. 2014; 121(8): 1598-1603.
    • (2014) Ophthalmology , vol.121 , Issue.8 , pp. 1598-1603
    • Cheung, C.M.1    Li, X.2    Cheng, C.Y.3
  • 27
    • 84867403686 scopus 로고    scopus 로고
    • Asian age-related macular degeneration phenotyping study: Rationale, design and protocol of a prospective cohort study
    • Cheung CM, Bhargava M, Laude A, et al. Asian age-related macular degeneration phenotyping study: rationale, design and protocol of a prospective cohort study. Clin Exp Ophthalmol. 2012; 40(7):727-735.
    • (2012) Clin Exp Ophthalmol. , vol.40 , Issue.7 , pp. 727-735
    • Cheung, C.M.1    Bhargava, M.2    Laude, A.3
  • 28
    • 85038420423 scopus 로고    scopus 로고
    • Choroidal remodeling in age-related macular degeneration and polypoidal choroidal vasculopathy: A 12-month prospective study
    • Ting DSW, Yanagi Y, Agrawal R, et al. Choroidal remodeling in age-related macular degeneration and polypoidal choroidal vasculopathy: a 12-month prospective study. Sci Rep. 2017; 7(1):7868.
    • (2017) Sci Rep. , vol.7 , Issue.1 , pp. 7868
    • Ting, D.S.W.1    Yanagi, Y.2    Agrawal, R.3
  • 29
    • 84956677857 scopus 로고    scopus 로고
    • Choroidal thickness changes in age-related macular degeneration and polypoidal choroidal vasculopathy: A 12-month prospective study
    • Ting DS, Ng WY, Ng SR, et al. Choroidal thickness changes in age-related macular degeneration and polypoidal choroidal vasculopathy: a 12-month prospective study. Am J Ophthalmol. 2016; 164:128-136.
    • (2016) Am J Ophthalmol. , vol.164 , pp. 128-136
    • Ting, D.S.1    Ng, W.Y.2    Ng, S.R.3
  • 30
    • 0042932653 scopus 로고    scopus 로고
    • Proposed international clinical diabetic retinopathy and diabetic macular edema disease severity scales
    • Wilkinson CP, Ferris FL III, Klein RE, et al; Global Diabetic Retinopathy Project Group. Proposed international clinical diabetic retinopathy and diabetic macular edema disease severity scales. Ophthalmology. 2003; 110(9):1677-1682.
    • (2003) Ophthalmology , vol.110 , Issue.9 , pp. 1677-1682
    • Wilkinson, C.P.1    Ferris, F.L.2    Klein, R.E.3
  • 32
  • 33
    • 85007536456 scopus 로고    scopus 로고
    • National Health Service (NHS) Diabetic Eye Screening Programme and Population Screening Programmes Accessed September 24, 2017
    • National Health Service (NHS) Diabetic Eye Screening Programme and Population Screening Programmes. Diabetic eye screening: commission and provide. https://www.gov.uk/government/collections/diabetic-eye-screening-commission-and-provide. 2015. Accessed September 24, 2017.
    • (2015) Diabetic Eye Screening: Commission and Provide
  • 34
    • 85009255599 scopus 로고    scopus 로고
    • Automated diabetic retinopathy image assessment software: Diagnostic accuracy and cost-effectiveness compared with human graders
    • Tufail A, Rudisill C, Egan C, et al. Automated diabetic retinopathy image assessment software: diagnostic accuracy and cost-effectiveness compared with human graders. Ophthalmology. 2017; 124(3):343-351.
    • (2017) Ophthalmology , vol.124 , Issue.3 , pp. 343-351
    • Tufail, A.1    Rudisill, C.2    Egan, C.3
  • 35
    • 85024386632 scopus 로고    scopus 로고
    • Telemedicine for diabetic retinopathy screening
    • Ting DSW, Tan GSW. Telemedicine for diabetic retinopathy screening. JAMA Ophthalmol. 2017; 135 (7):722-723.
    • (2017) JAMA Ophthalmol. , vol.135 , Issue.7 , pp. 722-723
    • Ting, D.S.W.1    Tan, G.S.W.2
  • 36
    • 77956403464 scopus 로고    scopus 로고
    • Nonparametric bootstrapping for hierarchical data
    • Ren S, Lai H, Tong W, Aminzadeh M, Hou X, Lai S. Nonparametric bootstrapping for hierarchical data. J Appl Stat. 2010; 37(9):1487-1498. doi:10.1080/02664760903046102
    • (2010) J Appl Stat. , vol.37 , Issue.9 , pp. 1487-1498
    • Ren, S.1    Lai, H.2    Tong, W.3    Aminzadeh, M.4    Hou, X.5    Lai, S.6
  • 37
    • 38949216071 scopus 로고    scopus 로고
    • Evaluation of a system for automatic detection of diabetic retinopathy from color fundus photographs in a large population of patients with diabetes
    • Abràmoff MD, Niemeijer M, Suttorp-Schulten MS, Viergever MA, Russell SR, van Ginneken B. Evaluation of a system for automatic detection of diabetic retinopathy from color fundus photographs in a large population of patients with diabetes. Diabetes Care. 2008; 31(2):193-198.
    • (2008) Diabetes Care , vol.31 , Issue.2 , pp. 193-198
    • Abràmoff, M.D.1    Niemeijer, M.2    Suttorp-Schulten, M.S.3    Viergever, M.A.4    Russell, S.R.5    Van Ginneken, B.6
  • 38
    • 77949389021 scopus 로고    scopus 로고
    • Automated early detection of diabetic retinopathy
    • Abràmoff MD, Reinhardt JM, Russell SR, et al. Automated early detection of diabetic retinopathy. Ophthalmology. 2010; 117(6):1147-1154.
    • (2010) Ophthalmology , vol.117 , Issue.6 , pp. 1147-1154
    • Abràmoff, M.D.1    Reinhardt, J.M.2    Russell, S.R.3
  • 39
    • 84862619470 scopus 로고    scopus 로고
    • Prevalence of diabetic retinopathy in various ethnic groups: A worldwide perspective
    • Sivaprasad S, Gupta B, Crosby-Nwaobi R, Evans J. Prevalence of diabetic retinopathy in various ethnic groups: a worldwide perspective. Surv Ophthalmol. 2012; 57(4):347-370.
    • (2012) Surv Ophthalmol. , vol.57 , Issue.4 , pp. 347-370
    • Sivaprasad, S.1    Gupta, B.2    Crosby-Nwaobi, R.3    Evans, J.4
  • 40
    • 84870574375 scopus 로고    scopus 로고
    • Accuracy of diabetic retinopathy screening by trained non-physician graders using non-mydriatic fundus camera
    • Bhargava M, Cheung CY, Sabanayagam C, et al. Accuracy of diabetic retinopathy screening by trained non-physician graders using non-mydriatic fundus camera. Singapore Med J. 2012; 53(11):715-719.
    • (2012) Singapore Med J. , vol.53 , Issue.11 , pp. 715-719
    • Bhargava, M.1    Cheung, C.Y.2    Sabanayagam, C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.