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Volumn 16, Issue 1, 2018, Pages 115-122.e10

Cost Effectiveness of Pre– vs Post–Liver Transplant Hepatitis C Treatment With Direct-Acting Antivirals

Author keywords

Health Economics; Simulation Model; Sofosbuvir

Indexed keywords

ANTIVIRUS AGENT; DIRECT ACTING ANTIVIRAL; LEDIPASVIR; LEDIPASVIR PLUS SOFOSBUVIR; RIBAVIRIN; SOFOSBUVIR; UNCLASSIFIED DRUG;

EID: 85038264786     PISSN: 15423565     EISSN: 15427714     Source Type: Journal    
DOI: 10.1016/j.cgh.2017.06.024     Document Type: Article
Times cited : (20)

References (41)
  • 1
    • 79959478969 scopus 로고    scopus 로고
    • Chronic hepatitis C infection
    • Rosen, H.R., Chronic hepatitis C infection. N Engl J Med 364 (2011), 2429–2438.
    • (2011) N Engl J Med , vol.364 , pp. 2429-2438
    • Rosen, H.R.1
  • 2
    • 84964657986 scopus 로고    scopus 로고
    • Management of hepatitis C before and after liver transplantation in the era of rapidly evolving therapeutic advances
    • Bunchorntavakul, C., Reddy, K.R., Management of hepatitis C before and after liver transplantation in the era of rapidly evolving therapeutic advances. J Clin Transl Hepatol 2 (2014), 124–133.
    • (2014) J Clin Transl Hepatol , vol.2 , pp. 124-133
    • Bunchorntavakul, C.1    Reddy, K.R.2
  • 3
    • 84855231089 scopus 로고    scopus 로고
    • Hepatitis C virus treatment pre- and post-liver transplantation
    • Roche, B., Samuel, D., Hepatitis C virus treatment pre- and post-liver transplantation. Liver Int 32 (2012), 120–128.
    • (2012) Liver Int , vol.32 , pp. 120-128
    • Roche, B.1    Samuel, D.2
  • 4
    • 84922879093 scopus 로고    scopus 로고
    • Sofosbuvir and ribavirin prevent recurrence of HCV infection after liver transplantation: an open-label study
    • Curry, M.P., Forns, X., Chung, R.T., et al. Sofosbuvir and ribavirin prevent recurrence of HCV infection after liver transplantation: an open-label study. Gastroenterology 148 (2015), 100–107.e101.
    • (2015) Gastroenterology , vol.148 , pp. 100-107.e101
    • Curry, M.P.1    Forns, X.2    Chung, R.T.3
  • 5
    • 84959368915 scopus 로고    scopus 로고
    • Model for end-stage liver disease limbo, model for end-stage liver disease purgatory, and the dilemma of treating hepatitis C in patients awaiting liver transplantation
    • Carrion, A.F., Khaderi, S.A., Sussman, N.L., Model for end-stage liver disease limbo, model for end-stage liver disease purgatory, and the dilemma of treating hepatitis C in patients awaiting liver transplantation. Liver Transplant 22 (2016), 279–280.
    • (2016) Liver Transplant , vol.22 , pp. 279-280
    • Carrion, A.F.1    Khaderi, S.A.2    Sussman, N.L.3
  • 6
    • 84938809007 scopus 로고    scopus 로고
    • Limited access to new hepatitis c virus treatment under state Medicaid programs
    • Canary, L.A., Klevens, R., Holmberg, S.D., Limited access to new hepatitis c virus treatment under state Medicaid programs. Ann Intern Med 163 (2015), 226–228.
    • (2015) Ann Intern Med , vol.163 , pp. 226-228
    • Canary, L.A.1    Klevens, R.2    Holmberg, S.D.3
  • 7
    • 85019473075 scopus 로고    scopus 로고
    • Treatment of patients waitlisted for liver transplant with an all-oral DAAs is a cost-effective treatment strategy in the United States
    • Ahmed, A., Gonzalez, S.A., Cholankeril, G., et al. Treatment of patients waitlisted for liver transplant with an all-oral DAAs is a cost-effective treatment strategy in the United States. Hepatology 66 (2017), 46–56.
    • (2017) Hepatology , vol.66 , pp. 46-56
    • Ahmed, A.1    Gonzalez, S.A.2    Cholankeril, G.3
  • 8
    • 84982787995 scopus 로고    scopus 로고
    • The optimal timing of hepatitis C therapy in transplant eligible patients with Child B and C cirrhosis: a cost-effectiveness analysis
    • Tapper, E.B., Hughes, M.S., Buti, M., et al. The optimal timing of hepatitis C therapy in transplant eligible patients with Child B and C cirrhosis: a cost-effectiveness analysis. Transplantation 101 (2017), 987–995.
    • (2017) Transplantation , vol.101 , pp. 987-995
    • Tapper, E.B.1    Hughes, M.S.2    Buti, M.3
  • 9
    • 84994850924 scopus 로고    scopus 로고
    • Optimal timing for hepatitis C therapy in US patients eligible for liver transplantation: a cost-effectiveness analysis
    • Njei, B., McCarty, T.R., Fortune, B.E., et al. Optimal timing for hepatitis C therapy in US patients eligible for liver transplantation: a cost-effectiveness analysis. Aliment Pharmacol Ther 44 (2016), 1090–1101.
    • (2016) Aliment Pharmacol Ther , vol.44 , pp. 1090-1101
    • Njei, B.1    McCarty, T.R.2    Fortune, B.E.3
  • 10
    • 85008457806 scopus 로고    scopus 로고
    • Optimal timing of hepatitis C treatment for patients on the liver transplant waiting list
    • Chhatwal, J., Samur, S., Kues, B., et al. Optimal timing of hepatitis C treatment for patients on the liver transplant waiting list. Hepatology 65 (2017), 777–788.
    • (2017) Hepatology , vol.65 , pp. 777-788
    • Chhatwal, J.1    Samur, S.2    Kues, B.3
  • 11
    • 84938953785 scopus 로고    scopus 로고
    • Ledipasvir and sofosbuvir plus ribavirin for treatment of HCV infection in patients with advanced liver disease
    • Charlton, M., Everson, G.T., Flamm, S.L., et al. Ledipasvir and sofosbuvir plus ribavirin for treatment of HCV infection in patients with advanced liver disease. Gastroenterology 149 (2015), 649–659.
    • (2015) Gastroenterology , vol.149 , pp. 649-659
    • Charlton, M.1    Everson, G.T.2    Flamm, S.L.3
  • 12
    • 84976260348 scopus 로고    scopus 로고
    • Ledipasvir and sofosbuvir plus ribavirin in patients with genotype 1 or 4 hepatitis C virus infection and advanced liver disease: a multicentre, open-label, randomised, phase 2 trial
    • Manns, M., Samuel, D., Gane, E.J., et al. Ledipasvir and sofosbuvir plus ribavirin in patients with genotype 1 or 4 hepatitis C virus infection and advanced liver disease: a multicentre, open-label, randomised, phase 2 trial. Lancet Infect Dis 16 (2016), 685–697.
    • (2016) Lancet Infect Dis , vol.16 , pp. 685-697
    • Manns, M.1    Samuel, D.2    Gane, E.J.3
  • 13
    • 85038241931 scopus 로고    scopus 로고
    • Ledipasvir/sofosbuvir with ribavirin in patients with decompensated cirrhosis or liver transplantation and HCV infection: SOLAR-1 and -2 trials (abstr 1049). In: Liver Meeting 2015, San Francisco, California.
    • Gane E, Manns M, McCaughan G, et al. Ledipasvir/sofosbuvir with ribavirin in patients with decompensated cirrhosis or liver transplantation and HCV infection: SOLAR-1 and -2 trials (abstr 1049). In: Liver Meeting 2015, San Francisco, California.
    • Gane, E.1    Manns, M.2    McCaughan, G.3
  • 14
    • 15744404869 scopus 로고    scopus 로고
    • A clinically based discrete-event simulation of end-stage liver disease and the organ allocation process
    • Shechter, S.M., Bryce, C.L., Alagoz, O., et al. A clinically based discrete-event simulation of end-stage liver disease and the organ allocation process. Med Decis Making 25 (2005), 199–209.
    • (2005) Med Decis Making , vol.25 , pp. 199-209
    • Shechter, S.M.1    Bryce, C.L.2    Alagoz, O.3
  • 15
    • 8344287555 scopus 로고    scopus 로고
    • The optimal timing of living-donor liver transplantation
    • Alagoz, O., Maillart, L.M., Schaefer, A.J., et al. The optimal timing of living-donor liver transplantation. Manage Sci 50 (2004), 1420–1430.
    • (2004) Manage Sci , vol.50 , pp. 1420-1430
    • Alagoz, O.1    Maillart, L.M.2    Schaefer, A.J.3
  • 16
    • 84855417506 scopus 로고    scopus 로고
    • MELD exceptions and rates of waiting list outcomes
    • Massie, A.B., Caffo, B., Gentry, S.E., et al. MELD exceptions and rates of waiting list outcomes. Am J Transplant 11 (2011), 2362–2371.
    • (2011) Am J Transplant , vol.11 , pp. 2362-2371
    • Massie, A.B.1    Caffo, B.2    Gentry, S.E.3
  • 17
    • 84860143214 scopus 로고    scopus 로고
    • Risk of advanced fibrosis with grafts from hepatitis C antibody-positive donors: a multicenter cohort study
    • Lai, J.C., O'Leary, J.G., Trotter, J.F., et al. Risk of advanced fibrosis with grafts from hepatitis C antibody-positive donors: a multicenter cohort study. Liver Transpl 18 (2012), 532–538.
    • (2012) Liver Transpl , vol.18 , pp. 532-538
    • Lai, J.C.1    O'Leary, J.G.2    Trotter, J.F.3
  • 18
    • 77953649164 scopus 로고    scopus 로고
    • Timing of hepatitis C antiviral therapy in patients with advanced liver disease: a decision analysis model
    • Saab, S., Hunt, D.R., Stone, M.A., et al. Timing of hepatitis C antiviral therapy in patients with advanced liver disease: a decision analysis model. Liver Transpl 16 (2010), 748–759.
    • (2010) Liver Transpl , vol.16 , pp. 748-759
    • Saab, S.1    Hunt, D.R.2    Stone, M.A.3
  • 19
    • 84856239637 scopus 로고    scopus 로고
    • All-cause and incremental per patient per year cost associated with chronic hepatitis C virus and associated liver complications in the United States: a managed care perspective
    • McAdam-Marx, C., McGarry, L.J., Hane, C.A., et al. All-cause and incremental per patient per year cost associated with chronic hepatitis C virus and associated liver complications in the United States: a managed care perspective. J Manag Care Pharm 17 (2011), 531–546.
    • (2011) J Manag Care Pharm , vol.17 , pp. 531-546
    • McAdam-Marx, C.1    McGarry, L.J.2    Hane, C.A.3
  • 20
    • 85038245017 scopus 로고    scopus 로고
    • RedBook Online 2014 Available from: Accessed: November 10.
    • RedBook Online 2014 Available from: http://www.redbook.com/redbook/online/. Accessed: November 10, 2015.
    • (2015)
  • 21
    • 84924901173 scopus 로고    scopus 로고
    • Cost-effectiveness and budget impact of hepatitis C virus treatment with sofosbuvir and ledipasvir in the United States
    • Chhatwal, J., Kanwal, F., Roberts, M.S., et al. Cost-effectiveness and budget impact of hepatitis C virus treatment with sofosbuvir and ledipasvir in the United States. Ann Intern Med 162 (2015), 397–406.
    • (2015) Ann Intern Med , vol.162 , pp. 397-406
    • Chhatwal, J.1    Kanwal, F.2    Roberts, M.S.3
  • 22
    • 41649118950 scopus 로고    scopus 로고
    • Surveillance of cirrhosis for hepatocellular carcinoma: a cost-utility analysis
    • Thompson Coon, J., Rogers, G., Hewson, P., et al. Surveillance of cirrhosis for hepatocellular carcinoma: a cost-utility analysis. Br J Cancer 98 (2008), 1166–1175.
    • (2008) Br J Cancer , vol.98 , pp. 1166-1175
    • Thompson Coon, J.1    Rogers, G.2    Hewson, P.3
  • 23
    • 0037345686 scopus 로고    scopus 로고
    • Health-state utilities and quality of life in hepatitis C patients
    • Chong, C.A.K.Y., Gulamhussein, A., Heathcote, E.J., et al. Health-state utilities and quality of life in hepatitis C patients. Am J Gastroenterol 98 (2003), 630–638.
    • (2003) Am J Gastroenterol , vol.98 , pp. 630-638
    • Chong, C.A.K.Y.1    Gulamhussein, A.2    Heathcote, E.J.3
  • 24
    • 84977527153 scopus 로고    scopus 로고
    • Delisting of liver transplant candidates with chronic hepatitis C after viral eradication: a European study
    • Belli, L.S., Berenguer, M., Cortesi, P.A., et al. Delisting of liver transplant candidates with chronic hepatitis C after viral eradication: a European study. J Hepatol 65 (2016), 524–531.
    • (2016) J Hepatol , vol.65 , pp. 524-531
    • Belli, L.S.1    Berenguer, M.2    Cortesi, P.A.3
  • 25
    • 84938953785 scopus 로고    scopus 로고
    • Ledipasvir and sofosbuvir plus ribavirin for treatment of HCV infection in patients with advanced liver disease
    • Charlton, M., Everson, G.T., Flamm, S.L., et al. Ledipasvir and sofosbuvir plus ribavirin for treatment of HCV infection in patients with advanced liver disease. Gastroenterology 149 (2015), 649–659.
    • (2015) Gastroenterology , vol.149 , pp. 649-659
    • Charlton, M.1    Everson, G.T.2    Flamm, S.L.3
  • 26
    • 84976260348 scopus 로고    scopus 로고
    • Ledipasvir and sofosbuvir plus ribavirin in patients with genotype 1 or 4 hepatitis C virus infection and advanced liver disease: a multicentre, open-label, randomised, phase 2 trial
    • Manns, M., Samuel, D., Gane, E.J., et al. Ledipasvir and sofosbuvir plus ribavirin in patients with genotype 1 or 4 hepatitis C virus infection and advanced liver disease: a multicentre, open-label, randomised, phase 2 trial. Lancet Infect Dis 16 (2016), 685–697.
    • (2016) Lancet Infect Dis , vol.16 , pp. 685-697
    • Manns, M.1    Samuel, D.2    Gane, E.J.3
  • 27
    • 85038219303 scopus 로고    scopus 로고
    • eds. Ledipasvir/sofosbuvir with ribavirin in patients with decompensated cirrhosis or liver transplantation and HCV infection: SOLAR-1 and -2 trials (abstr 1049). AASLD
    • Gane E, Manns M, McCaughan G, et al, eds. Ledipasvir/sofosbuvir with ribavirin in patients with decompensated cirrhosis or liver transplantation and HCV infection: SOLAR-1 and -2 trials (abstr 1049). AASLD 2015.
    • (2015)
    • Gane, E.1    Manns, M.2    McCaughan, G.3
  • 28
    • 8344287555 scopus 로고    scopus 로고
    • The optimal timing of living-donor liver transplantation
    • Alagoz, O., Maillart, L.M., Schaefer, A.J., et al. The optimal timing of living-donor liver transplantation. Manage Sci 50 (2004), 1420–1430.
    • (2004) Manage Sci , vol.50 , pp. 1420-1430
    • Alagoz, O.1    Maillart, L.M.2    Schaefer, A.J.3
  • 29
    • 84855417506 scopus 로고    scopus 로고
    • MELD exceptions and rates of waiting list outcomes
    • Massie, A.B., Caffo, B., Gentry, S.E., et al. MELD exceptions and rates of waiting list outcomes. Am J Transplant 11 (2011), 2362–2371.
    • (2011) Am J Transplant , vol.11 , pp. 2362-2371
    • Massie, A.B.1    Caffo, B.2    Gentry, S.E.3
  • 30
    • 77949850018 scopus 로고    scopus 로고
    • Liver transplantation in the United States, 1999–2008
    • Thuluvath, P., Guidinger, M., Fung, J., et al. Liver transplantation in the United States, 1999–2008. Am J Transplant 10 (2010), 1003–1019.
    • (2010) Am J Transplant , vol.10 , pp. 1003-1019
    • Thuluvath, P.1    Guidinger, M.2    Fung, J.3
  • 31
    • 18444415726 scopus 로고    scopus 로고
    • Contribution of donor age to the recent decrease in patient survival among HCV-infected liver transplant recipients
    • Berenguer, M., Prieto, M., San Juan, F., et al. Contribution of donor age to the recent decrease in patient survival among HCV-infected liver transplant recipients. Hepatology 36 (2002), 202–210.
    • (2002) Hepatology , vol.36 , pp. 202-210
    • Berenguer, M.1    Prieto, M.2    San Juan, F.3
  • 32
    • 0033807694 scopus 로고    scopus 로고
    • Natural history of clinically compensated hepatitis C virus-related graft cirrhosis after liver transplantation
    • Berenguer, M., Prieto, M., Rayon, J.M., et al. Natural history of clinically compensated hepatitis C virus-related graft cirrhosis after liver transplantation. Hepatology 32 (2000), 852–858.
    • (2000) Hepatology , vol.32 , pp. 852-858
    • Berenguer, M.1    Prieto, M.2    Rayon, J.M.3
  • 33
    • 0034125485 scopus 로고    scopus 로고
    • Recurrent hepatitis C after liver transplantation: clinical and therapeutical issues
    • Samuel, D., Feray, C., Recurrent hepatitis C after liver transplantation: clinical and therapeutical issues. J Viral Hepat 7 (2000), 87–92.
    • (2000) J Viral Hepat , vol.7 , pp. 87-92
    • Samuel, D.1    Feray, C.2
  • 34
    • 84860143214 scopus 로고    scopus 로고
    • Risk of advanced fibrosis with grafts from hepatitis C antibody-positive donors: a multicenter cohort study
    • Lai, J.C., O'Leary, J.G., Trotter, J.F., et al. Risk of advanced fibrosis with grafts from hepatitis C antibody-positive donors: a multicenter cohort study. Liver Transpl 18 (2012), 532–538.
    • (2012) Liver Transpl , vol.18 , pp. 532-538
    • Lai, J.C.1    O'Leary, J.G.2    Trotter, J.F.3
  • 35
    • 0037345686 scopus 로고    scopus 로고
    • Health-state utilities and quality of life in hepatitis C patients
    • Chong, C.A., Gulamhussein, A., Heathcote, E.J., et al. Health-state utilities and quality of life in hepatitis C patients. Am J Gastroenterol 98 (2003), 630–638.
    • (2003) Am J Gastroenterol , vol.98 , pp. 630-638
    • Chong, C.A.1    Gulamhussein, A.2    Heathcote, E.J.3
  • 36
    • 84924901173 scopus 로고    scopus 로고
    • Cost-effectiveness and budget impact of hepatitis C virus treatment with sofosbuvir and ledipasvir in the United States
    • Chhatwal, J., Kanwal, F., Roberts, M.S., et al. Cost-effectiveness and budget impact of hepatitis C virus treatment with sofosbuvir and ledipasvir in the United States. Ann Intern Med 162 (2015), 397–406.
    • (2015) Ann Intern Med , vol.162 , pp. 397-406
    • Chhatwal, J.1    Kanwal, F.2    Roberts, M.S.3
  • 37
    • 41649118950 scopus 로고    scopus 로고
    • Surveillance of cirrhosis for hepatocellular carcinoma: a cost-utility analysis
    • Thompson Coon, J., Rogers, G., Hewson, P., et al. Surveillance of cirrhosis for hepatocellular carcinoma: a cost-utility analysis. Br J Cancer 98 (2008), 1166–1175.
    • (2008) Br J Cancer , vol.98 , pp. 1166-1175
    • Thompson Coon, J.1    Rogers, G.2    Hewson, P.3
  • 38
    • 85038237559 scopus 로고    scopus 로고
    • 2015, Available from: Accessed: November 10.
    • RedBook online 2014. Available from: http://www.redbook.com/redbook/online/. Accessed: November 10, 2015.
    • (2014)
    • RedBook online1
  • 39
    • 84856239637 scopus 로고    scopus 로고
    • All-cause and incremental per patient per year cost associated with chronic hepatitis C virus and associated liver complications in the United States: a managed care perspective
    • McAdam-Marx, C., McGarry, L.J., Hane, C.A., et al. All-cause and incremental per patient per year cost associated with chronic hepatitis C virus and associated liver complications in the United States: a managed care perspective. J Manag Care Pharm 17 (2011), 531–546.
    • (2011) J Manag Care Pharm , vol.17 , pp. 531-546
    • McAdam-Marx, C.1    McGarry, L.J.2    Hane, C.A.3
  • 40
    • 77953649164 scopus 로고    scopus 로고
    • Timing of hepatitis C antiviral therapy in patients with advanced liver disease: a decision analysis model
    • Saab, S., Hunt, D.R., Stone, M.A., et al. Timing of hepatitis C antiviral therapy in patients with advanced liver disease: a decision analysis model. Liver Transpl 16 (2010), 748–759.
    • (2010) Liver Transpl , vol.16 , pp. 748-759
    • Saab, S.1    Hunt, D.R.2    Stone, M.A.3
  • 41
    • 33745893246 scopus 로고    scopus 로고
    • Report of nationally representative values for the noninstitutionalized US adult population for 7 health-related quality-of-life scores
    • Hanmer, J., Lawrence, W.F., Anderson, J.P., et al. Report of nationally representative values for the noninstitutionalized US adult population for 7 health-related quality-of-life scores. Med Decis Making 26 (2006), 391–400.
    • (2006) Med Decis Making , vol.26 , pp. 391-400
    • Hanmer, J.1    Lawrence, W.F.2    Anderson, J.P.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.