Risk of advanced fibrosis with grafts from hepatitis C antibody-positive donors: A multicenter cohort study

Liver Transplantation

Volumn 18, Issue 5, 2012, Pages 532-538

  Lai, Jennifer C ^a   O'Leary, Jacqueline G ^b   Trotter, James F ^b   Verna, Elizabeth C ^c   Brown, Robert S ^c   Stravitz, R Todd ^d   Duman, Jeffrey D ^e   Forman, Lisa M ^e   Terrault, Norah A ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b BAYLOR UNIVERSITY MEDICAL CENTER   (United States)

^c NewYork Presbyterian Hospital   (United States)

^d VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

^e UNIVERSITY OF COLORADO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HEPATITIS C ANTIBODY;

ADULT; AGE; ARTICLE; COHORT ANALYSIS; DONOR; FEMALE; GRAFT RECIPIENT; HEPATITIS C; HUMAN; LIVER FIBROSIS; LIVER GRAFT; LIVER TRANSPLANTATION; MAJOR CLINICAL STUDY; MALE; MULTICENTER STUDY; PRIORITY JOURNAL;

EID: 84860143214     PISSN: 15276465     EISSN: 15276473     Source Type: Journal    
DOI: 10.1002/lt.23396     Document Type: Article

References (20)

1. Organ Procurement and Transplantation Network. Data. Accessed February 2010.
2. Northup PG, Argo CK, Nguyen DT, McBride MA, Kumer SC, Schmitt TM, Pruett TL,. Liver allografts from hepatitis C positive donors can offer good outcomes in hepatitis C positive recipients: a US National Transplant Registry analysis. Transpl Int 2010; 23: 1038-1044.
3. Velidedeoglu E, Desai NM, Campos L, Olthoff KM, Shaked A, Nunes F, et al. The outcome of liver grafts procured from hepatitis C-positive donors. Transplantation 2002; 73: 582-587.
4. Burr AT, Li Y, Tseng JF, Saidi RF, Bozorgzadeh A, Shah SA,. Survival after liver transplantation using hepatitis C virus-positive donor allografts: case-controlled analysis of the UNOS database. World J Surg 2011; 35: 1590-1595.
5. Khapra AP, Agarwal K, Fiel MI, Kontorinis N, Hossain S, Emre S, Schiano TD,. Impact of donor age on survival and fibrosis progression in patients with hepatitis C undergoing liver transplantation using HCV+ allografts. Liver Transpl 2006; 12: 1496-1503.
6. Saab S, Ghobrial RM, Ibrahim AB, Kunder G, Durazo F, Han S, et al. Hepatitis C positive grafts may be used in orthotopic liver transplantation: a matched analysis. Am J Transplant 2003; 3: 1167-1172.
7. Saab S, Chang AJ, Comulada S, Geevarghese SK, Anselmo RD, Durazo F, et al. Outcomes of hepatitis C- and hepatitis B core antibody-positive grafts in orthotopic liver transplantation. Liver Transpl 2003; 9: 1053-1061.
8. Lai JC, Verna EC, Brown RS Jr, O'Leary JG, Trotter JF, Forman LM, et al.; for Consortium to Study Health Outcomes in HCV Liver Transplant Recipients (CRUSH-C). Hepatitis C virus-infected women have a higher risk of advanced fibrosis and graft loss after liver transplantation than men. Hepatology 2011; 54: 418-424.
9. Batts KP, Ludwig J,. Chronic hepatitis. An update on terminology and reporting. Am J Surg Pathol 1995; 19: 1409-1417.
10. Ishak K, Baptista A, Bianchi L, Callea F, De Groote J, Gudat F, et al. Histological grading and staging of chronic hepatitis. J Hepatol 1995; 22: 696-699.
11. Iakova P, Awad SS, Timchenko NA,. Aging reduces proliferative capacities of liver by switching pathways of C/EBPalpha growth arrest. Cell 2003; 113: 495-506.
12. Ballarin R, Cucchetti A, Spaggiari M, Montalti R, Di Benedetto F, Nadalin S, et al. Long-term follow-up and outcome of liver transplantation from anti-hepatitis C virus-positive donors: a European multicentric case-control study. Transplantation 2011; 91: 1265-1272.
13. El-Kamary SS, Jhaveri R, Shardell MD,. All-cause, liver-related, and non-liver-related mortality among HCV-infected individuals in the general US population. Clin Infect Dis 2011; 53: 150-157.
14. Murphy EL, Fang J, Tu Y, Cable R, Hillyer CD, Sacher R, et al.; for Retrovirus Epidemiology Donor Study. Hepatitis C virus prevalence and clearance among US blood donors, 2006-2007: associations with birth cohort, multiple pregnancies, and body mass index. J Infect Dis 2010; 202: 576-584.
15. Feng S, Goodrich NP, Bragg-Gresham JL, Dykstra DM, Punch JD, DebRoy MA, et al. Characteristics associated with liver graft failure: the concept of a donor risk index. Am J Transplant 2006; 6: 783-790.
16. Lai JC, Feng S, Roberts JP, Terrault NA,. Gender differences in liver donor quality are predictive of graft loss. Am J Transplant 2011; 11: 296-302.
17. Thuluvath PJ, Guidinger MK, Fung JJ, Johnson LB, Rayhill SC, Pelletier SJ,. Liver transplantation in the United States, 1999-2008. Am J Transplant 2010; 10 (pt 2): 1003-1019.
18. Wiley TE, Brown J, Chan J,. Hepatitis C infection in African Americans: its natural history and histological progression. Am J Gastroenterol 2002; 97: 700-706.
19. Terrault NA, Im K, Boylan R, Bacchetti P, Kleiner DE, Fontana RJ, Hoofnagle JH, Belle SH; VIRAHEP-C Study Group. Fibrosis progression in African Americans and Caucasian Americans with chronic hepatitis C. Clin Gastroenterol Hepatol 2008; 6: 1403-1411.
20. Bownik H, Saab S,. The effects of hepatitis C recurrence on health-related quality of life in liver transplant recipients. Liver Int 2010; 30: 19-30.