메뉴 건너뛰기




Volumn 8, Issue 66, 2017, Pages 110367-110379

Resminostat induces changes in epithelial plasticity of hepatocellular carcinoma cells and sensitizes them to sorafenibinduced apoptosis

Author keywords

EMT; HCC; HDAC inhibitors; Resminostat; Sorafenib

Indexed keywords

HERMES ANTIGEN; RESMINOSTAT; SORAFENIB;

EID: 85038095472     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.22775     Document Type: Article
Times cited : (26)

References (31)
  • 3
    • 84888198936 scopus 로고    scopus 로고
    • Role of epigenetic aberrations in the development and progression of human hepatocellular carcinoma
    • Pogribny I, Rusyn I. Role of epigenetic aberrations in the development and progression of human hepatocellular carcinoma. Cancer Lett. 2014; 342: 223-30.
    • (2014) Cancer Lett , vol.342 , pp. 223-230
    • Pogribny, I.1    Rusyn, I.2
  • 5
    • 37049001617 scopus 로고    scopus 로고
    • Clinical significance of histone deacetylase 1 expression in patients with hepatocellular carcinoma
    • Rikimaru T, Taketomi A, Yamashita Y, Shirabe K, Hamatsu T, Shimada M, Maehara Y. Clinical significance of histone deacetylase 1 expression in patients with hepatocellular carcinoma. Oncology. 2007; 72: 69-74.
    • (2007) Oncology , vol.72 , pp. 69-74
    • Rikimaru, T.1    Taketomi, A.2    Yamashita, Y.3    Shirabe, K.4    Hamatsu, T.5    Shimada, M.6    Maehara, Y.7
  • 6
    • 84949662280 scopus 로고    scopus 로고
    • A novel treatment strategy in hepatocellular carcinoma by downregulation of histone deacetylase 1 expression using a shRNA lentiviral system
    • Zhou H, Wang J, Peng G, Song Y, Zhang C. A novel treatment strategy in hepatocellular carcinoma by downregulation of histone deacetylase 1 expression using a shRNA lentiviral system. Int J Clin Exp Med. 2015; 8: 177721-9.
    • (2015) Int J Clin Exp Med , vol.8 , pp. 177721-177729
    • Zhou, H.1    Wang, J.2    Peng, G.3    Song, Y.4    Zhang, C.5
  • 10
    • 78650809075 scopus 로고    scopus 로고
    • Identification of histone deacetylase 3 as a biomarker for tumor recurrence following liver transplantation in HBV-associated hepatocellular carcinoma
    • Wu L, Yang Z, Zhou L, Zhang F, Xie H, Feng X, Wu J, Zheng S. Identification of histone deacetylase 3 as a biomarker for tumor recurrence following liver transplantation in HBV-associated hepatocellular carcinoma. PLoS One. 2010; 5: e14460.
    • (2010) PLoS One , vol.5
    • Wu, L.1    Yang, Z.2    Zhou, L.3    Zhang, F.4    Xie, H.5    Feng, X.6    Wu, J.7    Zheng, S.8
  • 11
    • 77951685547 scopus 로고    scopus 로고
    • The novel inhibitor of histone deacetylase resminostat (RAS2410) inhibits proliferation and induces apoptosis in multiple myeloma (MM) cells
    • Mandl-Weber S, Meinel F, Jankowsky R, Oduncu F, Schmidmaier R, Baumann P. The novel inhibitor of histone deacetylase resminostat (RAS2410) inhibits proliferation and induces apoptosis in multiple myeloma (MM) cells. Br J Haematol. 2010; 149: 518-28.
    • (2010) Br J Haematol , vol.149 , pp. 518-528
    • Mandl-Weber, S.1    Meinel, F.2    Jankowsky, R.3    Oduncu, F.4    Schmidmaier, R.5    Baumann, P.6
  • 17
    • 84933277181 scopus 로고    scopus 로고
    • Advances in targeted therapies for hepatocellular carcinoma in the genomic era
    • Llovet J, Villanueva A, Lachenmayer A, Finn R. Advances in targeted therapies for hepatocellular carcinoma in the genomic era. Nat Rev Clin Oncol. 2015; 12:408-24.
    • (2015) Nat Rev Clin Oncol. , vol.12 , pp. 408-424
    • Llovet, J.1    Villanueva, A.2    Lachenmayer, A.3    Finn, R.4
  • 18
    • 84986327387 scopus 로고    scopus 로고
    • HDAC inhibitors as epigenetic regulators of the immune system: impacts on cancer therapy and inflammatory diseases
    • Hull E, Montgomery M, Leyva K. HDAC inhibitors as epigenetic regulators of the immune system: impacts on cancer therapy and inflammatory diseases. Biomed Res Int. 2016; 8797206.
    • (2016) Biomed Res Int
    • Hull, E.1    Montgomery, M.2    Leyva, K.3
  • 19
    • 84979658623 scopus 로고    scopus 로고
    • Activation of mPTP-dependent mitochondrial apoptosis pathway by a novel pan HDAC inhibitor resminostat in hepatocellular carcinoma cells
    • Fu M, Shi W, Li Z, Liu H. Activation of mPTP-dependent mitochondrial apoptosis pathway by a novel pan HDAC inhibitor resminostat in hepatocellular carcinoma cells. Biochem Biophys Res Commun. 2016; 477: 527-33.
    • (2016) Biochem Biophys Res Commun , vol.477 , pp. 527-533
    • Fu, M.1    Shi, W.2    Li, Z.3    Liu, H.4
  • 20
    • 84895815986 scopus 로고    scopus 로고
    • Synergistic interaction between the HDAC inhibitor, MPT0E028, and sorafenib in liver cancer cells in vitro and in vivo
    • Chen C, Chen M, Wang J, Tsai A, Chen C, Liou J, Pan S, Teng C. Synergistic interaction between the HDAC inhibitor, MPT0E028, and sorafenib in liver cancer cells in vitro and in vivo. Clin Cancer Res. 2014; 20: 1274-87.
    • (2014) Clin Cancer Res , vol.20 , pp. 1274-1287
    • Chen, C.1    Chen, M.2    Wang, J.3    Tsai, A.4    Chen, C.5    Liou, J.6    Pan, S.7    Teng, C.8
  • 22
    • 84871721735 scopus 로고    scopus 로고
    • Long-term exposure to sorafenib of liver cancer cells induces resistance with epithelial-to-mesenchymal transition, increased invasion and risk of rebound growth
    • Malenstein Hv, Dekervel J, Verslype C, Cutsem Ev, Windmolders P, Nevens F, Pelt Jv. Long-term exposure to sorafenib of liver cancer cells induces resistance with epithelial-to-mesenchymal transition, increased invasion and risk of rebound growth. Cancer Lett. 2013; 329: 74-83.
    • (2013) Cancer Lett , vol.329 , pp. 74-83
    • Malenstein, Hv.1    Dekervel, J.2    Verslype, C.3    Cutsem, Ev.4    Windmolders, P.5    Nevens, F.6    Pelt, Jv.7
  • 23
    • 70450198396 scopus 로고    scopus 로고
    • Epithelialmesenchymal transitions in development and disease
    • Thiery J, Acloque H, Huang R, Nieto M. Epithelialmesenchymal transitions in development and disease. Cell. 2009; 139: 871-90.
    • (2009) Cell , vol.139 , pp. 871-890
    • Thiery, J.1    Acloque, H.2    Huang, R.3    Nieto, M.4
  • 24
    • 84887456252 scopus 로고    scopus 로고
    • The epigenetics of epithelialmesenchymal plasticity in cancer
    • Tam W, Weinberg R. The epigenetics of epithelialmesenchymal plasticity in cancer. Nat Med. 2013; 19: 1438-49.
    • (2013) Nat Med , vol.19 , pp. 1438-1449
    • Tam, W.1    Weinberg, R.2
  • 25
    • 77955094541 scopus 로고    scopus 로고
    • Histone deacetylase 1 is required for transforming growth factor-beta1-induced epithelial-mesenchymal transition
    • Lei W, Zhang K, Pan X, Hu Y, Wang D, Yuan X, Shu G, Song J. Histone deacetylase 1 is required for transforming growth factor-beta1-induced epithelial-mesenchymal transition. Int J Biochem Cell Biol. 2010; 42: 1489-97.
    • (2010) Int J Biochem Cell Biol , vol.42 , pp. 1489-1497
    • Lei, W.1    Zhang, K.2    Pan, X.3    Hu, Y.4    Wang, D.5    Yuan, X.6    Shu, G.7    Song, J.8
  • 26
    • 85011072597 scopus 로고    scopus 로고
    • The evolving concept of liver cancer stem cells
    • Nio K, Yamashita T, Kaneko S. The evolving concept of liver cancer stem cells. Mol Cancer. 2017; 16: 4.
    • (2017) Mol Cancer , vol.16 , pp. 4
    • Nio, K.1    Yamashita, T.2    Kaneko, S.3
  • 27
    • 85011283293 scopus 로고    scopus 로고
    • Epigenetics in cancer stem cells
    • Toh T, Lim J, Chow E. Epigenetics in cancer stem cells. Mol Cancer. 2017; 16: 29.
    • (2017) Mol Cancer , vol.16 , pp. 29
    • Toh, T.1    Lim, J.2    Chow, E.3
  • 28
    • 84973456757 scopus 로고    scopus 로고
    • New insights into the crossroads between EMT and stemness in the context of cancer
    • Fabregat I, Malfettone A, Soukupova J. New insights into the crossroads between EMT and stemness in the context of cancer. J Clin Med. 2016; 5: E37.
    • (2016) J Clin Med , vol.5 , pp. E37
    • Fabregat, I.1    Malfettone, A.2    Soukupova, J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.