Quantitative time-course metabolomics in human red blood cells reveal the temperature dependence of human metabolic networks

Journal of Biological Chemistry

Volumn 292, Issue 48, 2017, Pages 19556-19564

  Yurkovich, James T ^a   Zielinski, Daniel C ^a   Yang, Laurence ^a   Paglia, Giuseppe ^c   Rolfsson, Ottar ^d   Sigurjónsson, Ólafur E ^e,f   Broddrick, Jared T ^a,b   Bordbar, Aarash ^g   Wichuk, X Kristine ^d   Brynjólfsson, Sigurður ^d   Palsson, Sirus ^d,g   Gudmundsson, Sveinn ^e   Palsson, Bernhard O ^a,d  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^c University of Lubeck   (Italy)

^d UNIVERSITY OF ICELAND   (Iceland)

^e LANDSPITALI UNIVERSITY HOSPITAL   (Iceland)

^f REYKJAVIK UNIVERSITY   (Iceland)

^g Sinopia Biosciences   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BLOOD; CELLS; CHEMICAL ANALYSIS; METABOLITES; MULTIVARIANT ANALYSIS; TEMPERATURE DISTRIBUTION;

INCREASING TEMPERATURES; METABOLITE CONCENTRATIONS; MULTIVARIATE STATISTICAL ANALYSIS; NON-UNIFORM DISTRIBUTION; NUCLEOTIDE METABOLISM; TEMPERATURE DEPENDENCE; TEMPERATURE DIFFERENCES; TRANSLATIONAL REGULATION;

METABOLISM;

ADENINE; GLUCOSE; HYPOXANTHINE; LACTIC ACID; MALIC ACID; NICOTINAMIDE; PYROGLUTAMIC ACID; XANTHINE;

ARTICLE; BIOCHEMISTRY; CHEMICAL REACTION; ENZYME KINETICS; ERYTHROCYTE; ERYTHROCYTE METABOLISM; GLYCOLYSIS; HUMAN; HUMAN CELL; METABOLIC REGULATION; METABOLOMICS; NUCLEOTIDE METABOLISM; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; SYSTEMS BIOLOGY; TEMPERATURE; THERMODYNAMICS; TIME; TRANSCRIPTION REGULATION; TRANSLATION REGULATION; IN VITRO STUDY; METABOLISM; PROCEDURES;

ERYTHROCYTES; GLYCOLYSIS; HUMANS; IN VITRO TECHNIQUES; METABOLOMICS; TEMPERATURE;

EID: 85036453257     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M117.804914     Document Type: Article

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