메뉴 건너뛰기




Volumn 39, Issue , 2017, Pages 106-112

Global antimicrobial resistance in Gram-negative pathogens and clinical need

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTIC AGENT; ANTIINFECTIVE AGENT;

EID: 85034095356     PISSN: 13695274     EISSN: 18790364     Source Type: Journal    
DOI: 10.1016/j.mib.2017.10.028     Document Type: Review
Times cited : (127)

References (44)
  • 1
    • 85019545774 scopus 로고    scopus 로고
    • Global priority list of antibiotic-resistant bacteria to guide research, discovery, and development of new antibiotics
    • WHO published a priority pathogens list to guide and promote antibacterial drug R&D. It based on a multi-criteria decision analysis that incorporates both evidence-based data and expert opinion.
    • World Health Organization, Global priority list of antibiotic-resistant bacteria to guide research, discovery, and development of new antibiotics. 2017 http://www.who.int/medicines/publications/WHO-PPL-Short_Summary_25Feb-ET_NM_WHO.pdf WHO published a priority pathogens list to guide and promote antibacterial drug R&D. It based on a multi-criteria decision analysis that incorporates both evidence-based data and expert opinion.
    • (2017)
    • World Health Organization1
  • 2
    • 84992361685 scopus 로고    scopus 로고
    • Antimicrobial-resistant pathogens associated with healthcare-associated infections: summary of data reported to the National Healthcare Safety Network at the Centers for Disease Control and Prevention, 2011–2014
    • Weiner, L.M., Webb, A.K., Limbago, B., Dudeck, M.A., Patel, J., Kallen, A.J., Edwards, J.R., Sievert, D.M., Antimicrobial-resistant pathogens associated with healthcare-associated infections: summary of data reported to the National Healthcare Safety Network at the Centers for Disease Control and Prevention, 2011–2014. Infect Control Hosp Epidemiol 37 (2016), 1288–1301.
    • (2016) Infect Control Hosp Epidemiol , vol.37 , pp. 1288-1301
    • Weiner, L.M.1    Webb, A.K.2    Limbago, B.3    Dudeck, M.A.4    Patel, J.5    Kallen, A.J.6    Edwards, J.R.7    Sievert, D.M.8
  • 3
    • 72249087115 scopus 로고    scopus 로고
    • International study of the prevalence and outcomes of infection in intensive care units
    • Vincent, J., Rello, J., Marshall, J., et al. International study of the prevalence and outcomes of infection in intensive care units. JAMA 302 (2009), 2323–2329.
    • (2009) JAMA , vol.302 , pp. 2323-2329
    • Vincent, J.1    Rello, J.2    Marshall, J.3
  • 4
    • 84945139301 scopus 로고    scopus 로고
    • Infections caused by resistant Gram-negative bacteria: epidemiology and management
    • Kaye, K.S., Pogue, J.M., Infections caused by resistant Gram-negative bacteria: epidemiology and management. Pharmacotherapy 35 (2015), 949–962.
    • (2015) Pharmacotherapy , vol.35 , pp. 949-962
    • Kaye, K.S.1    Pogue, J.M.2
  • 5
    • 85016475359 scopus 로고    scopus 로고
    • Systematic review and meta-analysis of mortality of patients infected with carbapenem-resistant Klebsiella pneumoniae
    • Xu, L., Sun, X., Ma, X., Systematic review and meta-analysis of mortality of patients infected with carbapenem-resistant Klebsiella pneumoniae. Ann Clin Microbiol Antimicrob, 16, 2017, 18.
    • (2017) Ann Clin Microbiol Antimicrob , vol.16 , pp. 18
    • Xu, L.1    Sun, X.2    Ma, X.3
  • 6
    • 84933073491 scopus 로고    scopus 로고
    • Influence of carbapenem resistance on mortality of patients with Pseudomonas aeruginosa infection: a meta-analysis
    • Liu, Q., Li, X., Li, W., Du, X., He, J.-Q., Tao, C., Feng, Y., Influence of carbapenem resistance on mortality of patients with Pseudomonas aeruginosa infection: a meta-analysis. Sci Rep, 5, 2015, 11715.
    • (2015) Sci Rep , vol.5 , pp. 11715
    • Liu, Q.1    Li, X.2    Li, W.3    Du, X.4    He, J.-Q.5    Tao, C.6    Feng, Y.7
  • 7
    • 84901617771 scopus 로고    scopus 로고
    • Carbapenem resistance and mortality in patients with Acinetobacter baumannii infection: systematic review and meta-analysis
    • Performing a systematic review and meta-analysis, the authors show an influence of carbapenem-resistance on mortality compared to carbapenem-susceptibility though heterogeneity and confounding factors require a cautious interpretation of the results.
    • Lemos, E.V., de la Hoz, F.P., Einarson, T.R., McGhan, W.F., Quevedo, E., Castañeda, C., Kawai, K., Carbapenem resistance and mortality in patients with Acinetobacter baumannii infection: systematic review and meta-analysis. Clin Microbiol Inf 20 (2013), 416–423 Performing a systematic review and meta-analysis, the authors show an influence of carbapenem-resistance on mortality compared to carbapenem-susceptibility though heterogeneity and confounding factors require a cautious interpretation of the results.
    • (2013) Clin Microbiol Inf , vol.20 , pp. 416-423
    • Lemos, E.V.1    de la Hoz, F.P.2    Einarson, T.R.3    McGhan, W.F.4    Quevedo, E.5    Castañeda, C.6    Kawai, K.7
  • 8
    • 84875703277 scopus 로고    scopus 로고
    • Antimicrobial resistance and virulence: a successful or deleterious association in the bacterial world?
    • Beceiro, A., Tomás, M., Bou, G., Antimicrobial resistance and virulence: a successful or deleterious association in the bacterial world?. Clin Microbiol Rev 26 (2013), 185–230.
    • (2013) Clin Microbiol Rev , vol.26 , pp. 185-230
    • Beceiro, A.1    Tomás, M.2    Bou, G.3
  • 9
    • 85034022177 scopus 로고    scopus 로고
    • Increased mortality associated with bloodstream infections caused by Pseudomonas aeruginosa as compared to other bacteria: results of a 13-year prospective cohort study
    • Thaden, J.T., Park, L.P., Maskarinec, S.A., Ruffin, F., Fowler, V.G., van Duin, D., Increased mortality associated with bloodstream infections caused by Pseudomonas aeruginosa as compared to other bacteria: results of a 13-year prospective cohort study. Antimicrob Agents Chemother, 2017.
    • (2017) Antimicrob Agents Chemother
    • Thaden, J.T.1    Park, L.P.2    Maskarinec, S.A.3    Ruffin, F.4    Fowler, V.G.5    van Duin, D.6
  • 10
    • 84983486859 scopus 로고    scopus 로고
    • Trends in antibiotic resistance among major bacterial pathogens isolated from blood cultures tested at a large private laboratory network in India, 2008–2014
    • Gandra, S., Mojica, N., Klein, E.Y., Ashok, A., Nerurkar, V., Kumari, M., Ramesh, U., Dey, S., Vadwai, V., Das, B.R., et al. Trends in antibiotic resistance among major bacterial pathogens isolated from blood cultures tested at a large private laboratory network in India, 2008–2014. Int J Infect Dis 50 (2016), 75–82.
    • (2016) Int J Infect Dis , vol.50 , pp. 75-82
    • Gandra, S.1    Mojica, N.2    Klein, E.Y.3    Ashok, A.4    Nerurkar, V.5    Kumari, M.6    Ramesh, U.7    Dey, S.8    Vadwai, V.9    Das, B.R.10
  • 11
    • 84961189503 scopus 로고    scopus 로고
    • National epidemiology of carbapenem-resistant and extensively drug-resistant Gram-negative bacteria isolated from blood samples in China in 2013
    • Xu, A., Zheng, B., Xu, Y.C., Huang, Z.G., Zhong, N.S., Zhuo, C., Xu, A., Zheng, B., Xu, Y.C., Huang, Z.G., Zhong, N.S., Zhuo, C., National epidemiology of carbapenem-resistant and extensively drug-resistant Gram-negative bacteria isolated from blood samples in China in 2013. Clin Microbiol Inf 22 (2016), S1–S8.
    • (2016) Clin Microbiol Inf , vol.22 , pp. S1-S8
    • Xu, A.1    Zheng, B.2    Xu, Y.C.3    Huang, Z.G.4    Zhong, N.S.5    Zhuo, C.6    Xu, A.7    Zheng, B.8    Xu, Y.C.9    Huang, Z.G.10    Zhong, N.S.11    Zhuo, C.12
  • 12
    • 85006215387 scopus 로고    scopus 로고
    • Epidemiology and molecular characterization of multidrug-resistant Gram-negative bacteria in Southeast Asia
    • Suwantarat, N., Carroll, K.C., Epidemiology and molecular characterization of multidrug-resistant Gram-negative bacteria in Southeast Asia. Antimicrob Resist Infect Control, 5, 2016, 15.
    • (2016) Antimicrob Resist Infect Control , vol.5 , pp. 15
    • Suwantarat, N.1    Carroll, K.C.2
  • 16
    • 85006957610 scopus 로고    scopus 로고
    • Occurrence of carbapenemase-producing Klebsiella pneumoniae and Escherichia coli in the European survey of carbapenemase-producing Enterobacteriaceae (EuSCAPE): a prospective, multinational study
    • The EuSCAPE project provides information for monitoring incidence and spread of carbapenemases and carbapenemase-producing Enterobacteriaceae in Europe. The authors describe the change in carbapenemase epidemiology in Europe.
    • Grundmann, H., Glasner, C., Albiger, B., Aanensen, D.M., Tomlinson, C.T., Andrasević, A.T., Cantón, R., Carmeli, Y., Friedrich, A.W., Giske, C.G., et al. Occurrence of carbapenemase-producing Klebsiella pneumoniae and Escherichia coli in the European survey of carbapenemase-producing Enterobacteriaceae (EuSCAPE): a prospective, multinational study. Lancet Infect Dis 17 (2017), 153–163 The EuSCAPE project provides information for monitoring incidence and spread of carbapenemases and carbapenemase-producing Enterobacteriaceae in Europe. The authors describe the change in carbapenemase epidemiology in Europe.
    • (2017) Lancet Infect Dis , vol.17 , pp. 153-163
    • Grundmann, H.1    Glasner, C.2    Albiger, B.3    Aanensen, D.M.4    Tomlinson, C.T.5    Andrasević, A.T.6    Cantón, R.7    Carmeli, Y.8    Friedrich, A.W.9    Giske, C.G.10
  • 18
    • 85034021526 scopus 로고    scopus 로고
    • Antimicrobial Resistance Surveillance from sentinel public hospitals, South Africa, 2015
    • Perovic, O., Chetty, V., Antimicrobial Resistance Surveillance from sentinel public hospitals, South Africa, 2015. Commun Dis Surveill Bull 14 (2016), 56–67.
    • (2016) Commun Dis Surveill Bull , vol.14 , pp. 56-67
    • Perovic, O.1    Chetty, V.2
  • 20
    • 85019660287 scopus 로고    scopus 로고
    • In vitro activity of imipenem-relebactam against Gram-negative ESKAPE pathogens isolated by clinical laboratories in the United States in 2015 – results from the SMART Global Surveillance Program
    • Lob, S.H., Hackel, M.A., Kazmierczak, K.M., Young, K., Motyl, M.R., Karlowsky, J.A., Sahm, D.F., In vitro activity of imipenem-relebactam against Gram-negative ESKAPE pathogens isolated by clinical laboratories in the United States in 2015 – results from the SMART Global Surveillance Program. Antimicrob Agents Chemother, 2017, 10.1128/AAC.02209-16.
    • (2017) Antimicrob Agents Chemother
    • Lob, S.H.1    Hackel, M.A.2    Kazmierczak, K.M.3    Young, K.4    Motyl, M.R.5    Karlowsky, J.A.6    Sahm, D.F.7
  • 22
    • 85014112485 scopus 로고    scopus 로고
    • Pseudomonas aeruginosa antimicrobial susceptibility results from four years (2012 to 2015) of the international network for optimal resistance monitoring program in the United States
    • Sader, H.S., Huband, M.D., Castanheira, M., Flamm, R.K., Pseudomonas aeruginosa antimicrobial susceptibility results from four years (2012 to 2015) of the international network for optimal resistance monitoring program in the United States. Antimicrob Agents Chemother, 61, 2017, 10.1128/AAC.02252-16.
    • (2017) Antimicrob Agents Chemother , vol.61
    • Sader, H.S.1    Huband, M.D.2    Castanheira, M.3    Flamm, R.K.4
  • 24
    • 84962024912 scopus 로고    scopus 로고
    • Characterization of carbapenem resistance mechanisms and integrons in Pseudomonas aeruginosa strains from blood samples in a French hospital
    • Rojo-Bezares, B., Cavalié, L., Dubois, D., Oswald, E., Torres, C., Sáenz, Y., Characterization of carbapenem resistance mechanisms and integrons in Pseudomonas aeruginosa strains from blood samples in a French hospital. J Med Microbiol 65 (2016), 311–319.
    • (2016) J Med Microbiol , vol.65 , pp. 311-319
    • Rojo-Bezares, B.1    Cavalié, L.2    Dubois, D.3    Oswald, E.4    Torres, C.5    Sáenz, Y.6
  • 25
    • 84969555905 scopus 로고    scopus 로고
    • Characterization of clinical extensively drug-resistant Pseudomonas aeruginosa in the Hunan province of China
    • Li, J., Zou, M., Dou, Q., Hu, Y., Wang, H., Yan, Q., Liu, W.e., Characterization of clinical extensively drug-resistant Pseudomonas aeruginosa in the Hunan province of China. Ann Clin Microbiol Antimicrob, 15, 2016, 35.
    • (2016) Ann Clin Microbiol Antimicrob , vol.15 , pp. 35
    • Li, J.1    Zou, M.2    Dou, Q.3    Hu, Y.4    Wang, H.5    Yan, Q.6    Liu, W.E.7
  • 27
    • 85014605089 scopus 로고    scopus 로고
    • Trends in drug resistance of Acinetobacter baumannii over a 10-year period: nationwide data from the China Surveillance of Antimicrobial Resistance Program
    • Gao, L., Lyu, Y., Li, Y., Trends in drug resistance of Acinetobacter baumannii over a 10-year period: nationwide data from the China Surveillance of Antimicrobial Resistance Program. Chinese Med J 130 (2017), 659–664.
    • (2017) Chinese Med J , vol.130 , pp. 659-664
    • Gao, L.1    Lyu, Y.2    Li, Y.3
  • 29
    • 84990038764 scopus 로고    scopus 로고
    • Molecular characterization of carbapenem resistant Acinetobacter baumannii and investigation of genetic diversity between local and international clones
    • Ahmed, S.S., Dinc, G., Rossella, B., Alp, E., Ulu-Kilic, A., Melchers, W.J.G., Hopman, J., Voss, A., Molecular characterization of carbapenem resistant Acinetobacter baumannii and investigation of genetic diversity between local and international clones. J Pure Applied Microbiol 10 (2016), 1675–1682.
    • (2016) J Pure Applied Microbiol , vol.10 , pp. 1675-1682
    • Ahmed, S.S.1    Dinc, G.2    Rossella, B.3    Alp, E.4    Ulu-Kilic, A.5    Melchers, W.J.G.6    Hopman, J.7    Voss, A.8
  • 30
    • 85006105982 scopus 로고    scopus 로고
    • Molecular characterization of invasive carbapenem-resistant Acinetobacter baumannii from a tertiary care hospital in South India
    • Vijayakumar, S., Gopi, R., Gunasekaran, P., Bharathy, M., Walia, K., Anandan, S., Veeraraghavan, B., Molecular characterization of invasive carbapenem-resistant Acinetobacter baumannii from a tertiary care hospital in South India. Inf Dis Therapy 5 (2016), 379–387.
    • (2016) Inf Dis Therapy , vol.5 , pp. 379-387
    • Vijayakumar, S.1    Gopi, R.2    Gunasekaran, P.3    Bharathy, M.4    Walia, K.5    Anandan, S.6    Veeraraghavan, B.7
  • 31
    • 85018329778 scopus 로고    scopus 로고
    • Clonality, virulence determinants, and profiles of resistance of clinical Acinetobacter baumannii isolates obtained from a Spanish hospital
    • Dahdouh, E., Gomez-Gil, R., Pacho, S., Mingorance, J., Daoud, Z., Suarez, M., Clonality, virulence determinants, and profiles of resistance of clinical Acinetobacter baumannii isolates obtained from a Spanish hospital. PLOS ONE, 12, 2017, e0176824.
    • (2017) PLOS ONE , vol.12 , pp. e0176824
    • Dahdouh, E.1    Gomez-Gil, R.2    Pacho, S.3    Mingorance, J.4    Daoud, Z.5    Suarez, M.6
  • 32
    • 84961201458 scopus 로고    scopus 로고
    • Treatment options for infections caused by carbapenem-resistant Enterobacteriaceae: can we apply “precision medicine” to antimicrobial chemotherapy?
    • This informative overview of carbapenem-resistant Enterobacteriaceae describes resistance mechanisms, epidemiology, clinical impact, treatment options as well as some new beta-lactamase inhibitor combinations.
    • Perez, F., El Chakhtoura, N.G., Papp-Wallace, K.M., Wilson, B.M., Bonomo, R.A., Treatment options for infections caused by carbapenem-resistant Enterobacteriaceae: can we apply “precision medicine” to antimicrobial chemotherapy?. Expert Opin Pharmacother 17 (2016), 761–781 This informative overview of carbapenem-resistant Enterobacteriaceae describes resistance mechanisms, epidemiology, clinical impact, treatment options as well as some new beta-lactamase inhibitor combinations.
    • (2016) Expert Opin Pharmacother , vol.17 , pp. 761-781
    • Perez, F.1    El Chakhtoura, N.G.2    Papp-Wallace, K.M.3    Wilson, B.M.4    Bonomo, R.A.5
  • 33
    • 84946567642 scopus 로고    scopus 로고
    • A resurgence of beta-lactamase inhibitor combinations effective against multidrug-resistant Gram-negative pathogens
    • Overview of recently approved and future beta-lactamase inhibitor combinations. The review explains the different chemical classes of beta-lactamase inhibitors and compares their activities.
    • Bush, K., A resurgence of beta-lactamase inhibitor combinations effective against multidrug-resistant Gram-negative pathogens. Int J Antimicrob Agents 46 (2015), 483–493 Overview of recently approved and future beta-lactamase inhibitor combinations. The review explains the different chemical classes of beta-lactamase inhibitors and compares their activities.
    • (2015) Int J Antimicrob Agents , vol.46 , pp. 483-493
    • Bush, K.1
  • 35
    • 84983238987 scopus 로고    scopus 로고
    • Effect of the beta-Lactamase inhibitor vaborbactam combined with meropenem against serine carbapenemase-producing Enterobacteriaceae
    • Castanheira, M., Rhomberg, P.R., Flamm, R.K., Jones, R.N., Effect of the beta-Lactamase inhibitor vaborbactam combined with meropenem against serine carbapenemase-producing Enterobacteriaceae. Antimicrob Agents Chemother 60 (2016), 5454–5458.
    • (2016) Antimicrob Agents Chemother , vol.60 , pp. 5454-5458
    • Castanheira, M.1    Rhomberg, P.R.2    Flamm, R.K.3    Jones, R.N.4
  • 36
    • 85018175507 scopus 로고    scopus 로고
    • WCK 5222 (Cefepime-Zidebactam) antimicrobial activity against clinical isolates of Gram-negative bacteria collected worldwide in 2015
    • Sader, H.S., Castanheira, M., Huband, M., Jones, R.N., Flamm, R.K., WCK 5222 (Cefepime-Zidebactam) antimicrobial activity against clinical isolates of Gram-negative bacteria collected worldwide in 2015. Antimicrob Agents Chemother, 61, 2017, 10.1128/AAC.00072-17.
    • (2017) Antimicrob Agents Chemother , vol.61
    • Sader, H.S.1    Castanheira, M.2    Huband, M.3    Jones, R.N.4    Flamm, R.K.5
  • 37
    • 85020135744 scopus 로고    scopus 로고
    • In vitro activity of cefepime/zidebactam (WCK 5222) against Gram-negative bacteria
    • Livermore, D.M., Mushtaq, S., Warner, M., Vickers, A., Woodford, N., In vitro activity of cefepime/zidebactam (WCK 5222) against Gram-negative bacteria. J Antimicrob Chemother 72 (2017), 1373–1385.
    • (2017) J Antimicrob Chemother , vol.72 , pp. 1373-1385
    • Livermore, D.M.1    Mushtaq, S.2    Warner, M.3    Vickers, A.4    Woodford, N.5
  • 39
    • 85027334480 scopus 로고    scopus 로고
    • Activity of cefiderocol (S-649266) against carbapenem-resistant Gram-negative bacteria collected from inpatients in Greek hospitals
    • Falagas, M.E., Skalidis, T., Vardakas, K.Z., Legakis, N.J., Hellenic Cefiderocol Study, G., Activity of cefiderocol (S-649266) against carbapenem-resistant Gram-negative bacteria collected from inpatients in Greek hospitals. J Antimicrob Chemother, 2017, 10.1128/AAC.00072-17.
    • (2017) J Antimicrob Chemother
    • Falagas, M.E.1    Skalidis, T.2    Vardakas, K.Z.3    Legakis, N.J.4    Hellenic Cefiderocol Study, G.5
  • 40
    • 84905393404 scopus 로고    scopus 로고
    • Carbapenem-resistant Klebsiella pneumoniae strains exhibit diversity in aminoglycoside-modifying enzymes, which exert differing effects on plazomicin and other agents
    • Almaghrabi, R., Clancy, C.J., Doi, Y., Hao, B., Chen, L., Shields, R.K., Press, E.G., Iovine, N.M., Townsend, B.M., Wagener, M.M., et al. Carbapenem-resistant Klebsiella pneumoniae strains exhibit diversity in aminoglycoside-modifying enzymes, which exert differing effects on plazomicin and other agents. Antimicrob Agents Chemother 58 (2014), 4443–4451.
    • (2014) Antimicrob Agents Chemother , vol.58 , pp. 4443-4451
    • Almaghrabi, R.1    Clancy, C.J.2    Doi, Y.3    Hao, B.4    Chen, L.5    Shields, R.K.6    Press, E.G.7    Iovine, N.M.8    Townsend, B.M.9    Wagener, M.M.10
  • 41
    • 85019677213 scopus 로고    scopus 로고
    • Occurrence of acquired 16s methyltransferase mediated aminoglycoside resistance in clinical isolates of Enterobacteriaceae within a tertiary referral hospital of northeast India
    • Wangkheimayum, J., Paul, D., Dhar, D., Nepram, R., Chetri, S., Bhowmik, D., Chakravarty, A., Bhattacharjee, A., Occurrence of acquired 16s methyltransferase mediated aminoglycoside resistance in clinical isolates of Enterobacteriaceae within a tertiary referral hospital of northeast India. Antimicrob Agents Chemother, 2017, 10.1128/AAC.01037-16.
    • (2017) Antimicrob Agents Chemother
    • Wangkheimayum, J.1    Paul, D.2    Dhar, D.3    Nepram, R.4    Chetri, S.5    Bhowmik, D.6    Chakravarty, A.7    Bhattacharjee, A.8
  • 42
    • 84973616512 scopus 로고    scopus 로고
    • In vitro activity of eravacycline against carbapenem-resistant Enterobacteriaceae and Acinetobacter baumannii
    • Livermore, D.M., Mushtaq, S., Warner, M., Woodford, N., In vitro activity of eravacycline against carbapenem-resistant Enterobacteriaceae and Acinetobacter baumannii. Antimicrob Agents Chemother 60 (2016), 3840–3844.
    • (2016) Antimicrob Agents Chemother , vol.60 , pp. 3840-3844
    • Livermore, D.M.1    Mushtaq, S.2    Warner, M.3    Woodford, N.4
  • 43
    • 84874083043 scopus 로고    scopus 로고
    • Antimicrobial peptidomimetics: reinterpreting nature to deliver innovative therapeutics
    • Scorciapino, M.A., Rinaldi, A.C., Antimicrobial peptidomimetics: reinterpreting nature to deliver innovative therapeutics. Front Immunol, 3, 2012, 171.
    • (2012) Front Immunol , vol.3 , pp. 171
    • Scorciapino, M.A.1    Rinaldi, A.C.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.