Conformational changes in the 5' end of the HIV-1 genome dependent on the debranching enzyme DBR1 during early stages of infection

Journal of Virology

Volumn 91, Issue 23, 2017, Pages

  Galvis, Alvaro E ^a,b   Fisher, Hugh E ^b   Fan, Hung ^a,b   Camerini, David ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

DBR1; Human immunodeficiency virus; Reverse transcription

Indexed keywords

2' 5' PHOSPHATASE; COMPLEMENTARY DNA; DEBRANCHING ENZYME; PHOSPHATASE; RIBONUCLEASE; RNA DIRECTED DNA POLYMERASE; SHORT HAIRPIN RNA; UNCLASSIFIED DRUG; VIRUS ENZYME; VIRUS RNA; VIRUS VECTOR; CAPPED RNA; DBR1 PROTEIN, HUMAN; RNA POLYMERASE; RNA PRECURSOR; SMALL INTERFERING RNA;

5' UNTRANSLATED REGION; ARTICLE; CONTROLLED STUDY; EMBRYO; ENZYME ACTIVITY; ENZYME DEGRADATION; ENZYME SYNTHESIS; GENE AMPLIFICATION; GENE SILENCING; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; IN VITRO STUDY; INCUBATION TIME; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA CONFORMATION; RNA ISOLATION; RNA STRUCTURE; VIRUS GENOME; VIRUS INFECTION; VIRUS REPLICATION; CHEMISTRY; DEFICIENCY; DRUG EFFECTS; GENETICS; HEK293 CELL LINE; METABOLISM; PHYSIOLOGY; REVERSE TRANSCRIPTION; RNA SPLICING; SACCHAROMYCES CEREVISIAE;

GENOME, VIRAL; HEK293 CELLS; HIV-1; HUMANS; REVERSE TRANSCRIPTION; RNA CAPS; RNA NUCLEOTIDYLTRANSFERASES; RNA PRECURSORS; RNA SPLICING; RNA, SMALL INTERFERING; RNA, VIRAL; SACCHAROMYCES CEREVISIAE; VIRUS REPLICATION;

EID: 85033779388     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.01377-17     Document Type: Article

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