Selective effects of psychotherapy on frontopolar cortical function in PTSD

American Journal of Psychiatry

Volumn 174, Issue 12, 2017, Pages 1175-1184

  Fonzo, Gregory A ^a,b,c,d,e,f   Goodkind, Madeleine S ^a,b,c,d,e,f   Oathes, Desmond J ^a,b,c,d,e,f   Zaiko, Yevgeniya V ^a,b,c,d,e,f   Harvey, Meredith ^a,b,c,d,e,f   Peng, Kathy K ^a,b,c,d,e,f   Weiss, M Elizabeth ^a,b,c,d,e,f   Thompson, Allison L ^a,b,c,d,e,f   Zack, Sanno E ^a,b,c,d,e,f   Mills Finnerty, Colleen E ^a,b,c,d,e,f   Rosenberg, Benjamin M ^a,b,c,d,e,f   Edelstein, Raleigh ^a,b,c,d,e,f   Wright, Rachael N ^a,b,c,d,e,f   Kole, Carena A ^a,b,c,d,e,f   Lindley, Steven E ^a,b,c,d,e,f   Arnow, Bruce A ^a,b,c,d,e,f   Jo, Booil ^a,b,c,d,e,f   Gross, James J ^a,b,c,d,e,f   Rothbaum, Barbara O ^a,b,c,d,e,f   Etkin, Amit ^a,b,c,d,e,f  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b STANFORD UNIVERSITY   (United States)

^c VA PALO ALTO HEALTH CARE SYSTEM   (United States)

^d New Mexico Veterans Affairs (VA) Healthcare System   (United States)

^e UNIVERSITY OF PENNSYLVANIA   (United States)

^f EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; AFFECT; AROUSAL; ARTICLE; BRAIN FUNCTION; BRAIN REGION; CLINICAL ARTICLE; COGNITION; CONTROLLED STUDY; EMOTION; EMOTIONALITY; EXPOSURE THERAPY; FRONTAL CORTEX; FUNCTIONAL CONNECTIVITY; FUNCTIONAL MAGNETIC RESONANCE IMAGING; HUMAN; MIDDLE AGED; POSTTRAUMATIC STRESS DISORDER; PRIORITY JOURNAL; PSYCHOLOGICAL WELL-BEING; PSYCHOTHERAPY; REST; TASK PERFORMANCE; TRANSCRANIAL MAGNETIC STIMULATION; TREATMENT OUTCOME; VENTRAL STRIATUM; VENTROMEDIAL PREFRONTAL CORTEX; YOUNG ADULT; ADOLESCENT; CORPUS STRIATUM; FEMALE; FRONTAL LOBE; FUNCTIONAL NEUROIMAGING; IMPLOSIVE THERAPY; MALE; NERVE TRACT; NUCLEAR MAGNETIC RESONANCE IMAGING; PATHOPHYSIOLOGY; PHYSIOLOGY; PREFRONTAL CORTEX; RANDOMIZED CONTROLLED TRIAL;

ADOLESCENT; ADULT; CORPUS STRIATUM; EMOTIONS; FEMALE; FRONTAL LOBE; FUNCTIONAL NEUROIMAGING; HUMANS; IMPLOSIVE THERAPY; MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGED; NEURAL PATHWAYS; PREFRONTAL CORTEX; STRESS DISORDERS, POST-TRAUMATIC; TRANSCRANIAL MAGNETIC STIMULATION; TREATMENT OUTCOME; YOUNG ADULT;

EID: 85033546798     PISSN: 0002953X     EISSN: 15357228     Source Type: Journal    
DOI: 10.1176/appi.ajp.2017.16091073     Document Type: Article

References (47)

1. Marmar CR, Schlenger W, Henn-Haase C, et al: Course of posttraumatic stress disorder 40 years after the Vietnam War: findings from the National Vietnam Veterans Longitudinal Study. JAMA Psychiatry 2015; 72:875-881
2. Schnurr PP, Lunney CA, Bovin MJ, et al: Posttraumatic stress disorder and quality of life: extension of findings to veterans of the wars in Iraq and Afghanistan. Clin Psychol Rev 2009; 29:727-735
3. Cusack K, Jonas DE, Forneris CA, et al: Psychological treatments for adults with posttraumatic stress disorder: a systematic review and meta-analysis. Clin Psychol Rev 2016; 43:128-141
4. Foa EB, Gillihan SJ, Bryant RA: Challenges and successes in dissemination of evidence-based treatments for posttraumatic stress: lessons learned from prolonged exposure therapy for PTSD. Psychol Sci Public Interest 2013; 14:65-111
5. Foa EB, Hembree EA, Rothbaum BO: Prolonged Exposure Therapy for PTSD. Oxford, UK, Oxford University Press, 2007
6. Foa EB, Kozak MJ: Emotional processing of fear: exposure to corrective information. Psychol Bull 1986; 99:20-35
7. Bohning DE, Shastri A, McGavin L, et al: Motor cortex brain activity induced by 1-Hz transcranial magnetic stimulation is similar in location andlevel to that for volitionalmovement. InvestRadiol 2000; 35:676-683
8. Levin P, Lazrove S, van der Kolk B: What psychological testing and neuroimaging tell us about the treatment of posttraumatic stress disorder by eye movement desensitization and reprocessing. J Anxiety Disord 1999; 13:159-172
9. Lansing K, Amen DG, Hanks C, et al: High-resolution brain SPECT imaging and eye movement desensitization and reprocessing in police officers with PTSD. J Neuropsychiatry Clin Neurosci 2005; 17:526-532
10. Peres JF, Newberg AB, Mercante JP, et al: Cerebral blood flow changes during retrieval of traumatic memories before and after psychotherapy: a SPECT study. Psychol Med 2007; 37:1481-1491
11. Lindauer RJ, Booij J, Habraken JB, et al: Effects of psychotherapy on regional cerebral blood flowduring trauma imagery in patients with post-traumatic stress disorder: a randomized clinical trial. Psychol Med 2008; 38:543-554
12. Aupperle RL, Allard CB, Simmons AN, et al: Neural responses during emotional processing before and after cognitive trauma therapy for battered women. Psychiatry Res 2013; 214:48-55
13. Rabe S, Zoellner T, Beauducel A, et al: Changes in brain electrical activity after cognitive behavioral therapy for posttraumatic stress disorder in patientsinjuredinmotorvehicleaccidents. Psychosom Med 2008;70:13-19
14. Thomaes K, Dorrepaal E, Draijer N, et al: Treatment effects on insular and anterior cingulate cortex activation during classic and emotional Stroop interference in child abuse-related complex posttraumatic stress disorder. Psychol Med 2012; 42:2337-2349
15. Felmingham K, Kemp A, Williams L, et al: Changes in anterior cingulate and amygdala after cognitive behavior therapy of posttraumatic stress disorder. Psychol Sci 2007; 18:127-129
16. Peres JF, Foerster B, Santana LG, et al: Police officers under attack: resilienceimplicationsof an fMRI study. J Psychiatr Res 2011;45:727-734
17. Roy MJ, Francis J, Friedlander J, et al: Improvement in cerebral function with treatment of posttraumatic stress disorder. Ann N Y Acad Sci 2010; 1208:142-149
18. Brooks SJ, Stein DJ: A systematic review of the neural bases of psychotherapy for anxiety and related disorders. Dialogues Clin Neurosci 2015; 17:261-279
19. Etkin A, Klemenhagen KC, Dudman JT, et al: Individual differences in trait anxiety predict the response of the basolateral amygdala to unconsciously processed fearful faces. Neuron 2004; 44:1043-1055
20. Etkin A, Schatzberg AF: Common abnormalities and disorderspecific compensation during implicit regulation of emotional processing in generalized anxiety and major depressive disorders. Am J Psychiatry 2011; 168:968-978
21. Minkel JD, McNealy K, Gianaros PJ, et al: Sleep quality and neural circuit function supporting emotion regulation. Biol Mood Anxiety Disord 2012; 2:22
22. Chen AC, Oathes DJ, Chang C, et al: Causal interactions between fronto-parietal central executive and default-mode networks in humans. Proc Natl Acad Sci USA 2013; 110:19944-19949
23. Shannon CE: A mathematical theory of communication. Bell System Technical Journal 1948; 27:379-423
24. WangZ, Li Y, Childress AR, et al: Brain entropy mapping using fMRI. PLoS One 2014; 9:e89948
25. Shuiabi E, Thomson V, Bhuiyan N: Entropy as a measure of operational flexibility. Eur J Oper Res 2005; 165:696-707
26. Kraemer HC, Wilson GT, Fairburn CG, et al: Mediators and moderators of treatment effects in randomized clinical trials. Arch Gen Psychiatry 2002; 59:877-883
27. McLaren DG, Ries ML, Xu G, et al: A generalized form of contextdependent psychophysiological interactions (gPPI): a comparison to standard approaches. Neuroimage 2012; 61:1277-1286
28. Daw ND, O'Doherty JP, Dayan P, et al: Cortical substrates for exploratory decisions in humans. Nature 2006; 441:876-879
29. Burgess PW, Dumontheil I, Gilbert SJ: The gateway hypothesis of rostral prefrontal cortex (area 10) function. Trends Cogn Sci 2007; 11: 290-298
30. Turner MS, Simons JS, Gilbert SJ, et al: Distinct roles for lateral and medial rostral prefrontal cortex in source monitoring of perceived and imagined events. Neuropsychologia 2008; 46:1442-1453
31. RamnaniN, OwenAM:Anterior prefrontal cortex: insights into function from anatomy and neuroimaging. Nat Rev Neurosci 2004; 5:184-194
32. Milad MR, Rosenbaum BL, Simon NM: Neuroscience of fear extinction: implications for assessmentandtreatment of fear-basedand anxiety related disorders. Behav Res Ther 2014; 62:17-23
33. Buhle JT, Silvers JA, Wager TD, et al: Cognitive reappraisal of emotion: a meta-analysis of human neuroimaging studies. Cereb Cortex 2014; 24:2981-2990
34. Fonzo GA, Goodkind MS, Oathes DJ, et al: PTSD psychotherapy outcome predicted by brain activation during emotional reactivity and regulation. Am J Psychiatry 2017; 174:1163-1174
35. Messina I, Sambin M, Palmieri A, et al: Neural correlates of psychotherapy in anxiety and depression: a meta-analysis. PLoS One 2013; 8:e74657
36. Seeley WW, Menon V, Schatzberg AF, et al: Dissociable intrinsic connectivity networks for salience processing and executive control. J Neurosci 2007; 27:2349-2356
37. Yarkoni T, Poldrack RA, Nichols TE, et al: Large-scale automated synthesis ofhumanfunctionalneuroimaging data.NatMethods2011; 8:665-670
38. Kalisch R: The functional neuroanatomy of reappraisal: time matters. Neurosci Biobehav Rev 2009; 33:1215-1226
39. Patel R, Spreng RN, Shin LM, et al: Neurocircuitry models of posttraumatic stress disorder and beyond: a meta-analysis of functional neuroimaging studies. Neurosci Biobehav Rev 2012; 36:2130-2142
40. Critchley HD, Nagai Y, Gray MA, et al: Dissecting axes of autonomic control in humans: insights from neuroimaging. Auton Neurosci 2011; 161:34-42
41. Wager TD, Davidson ML, Hughes BL, et al: Prefrontal-subcortical pathways mediating successful emotion regulation. Neuron 2008; 59:1037-1050
42. Burgess PW, Gilbert SJ, Dumontheil I: Function and localization within rostral prefrontal cortex (area 10). Philos Trans R Soc Lond B Biol Sci 2007; 362:887-899
43. Kilts CD, Kelsey JE, Knight B, et al: The neural correlates of social anxiety disorder and response to pharmacotherapy. Neuropsychopharmacology 2006; 31:2243-2253
44. Klumpp H, Fitzgerald DA, Phan KL: Neural predictors andmechanisms of cognitive behavioral therapy on threat processing in social anxiety disorder. Prog Neuropsychopharmacol Biol Psychiatry 2013; 45:83-91
45. Nahas Z, Anderson BS, Borckardt J, et al: Bilateral epidural prefrontal cortical stimulation for treatment-resistant depression. Biol Psychiatry 2010; 67:101-109
46. Yamanishi T, Nakaaki S, Omori IM, et al: Changes after behavior therapy among responsive and nonresponsive patients with obsessivecompulsive disorder. Psychiatry Res 2009; 172:242-250
47. Nagai Y, Critchley HD, Featherstone E, et al: Activity in ventromedial prefrontal cortex covaries with sympathetic skin conductance level: a physiological account of a "default mode" of brain function. Neuroimage 2004; 22:243-251