메뉴 건너뛰기




Volumn 6, Issue 3, 2017, Pages

Protocol for combined analysis of FOXFIRE, SIRFLOX, and FOXFIRE-global randomized phase III trials of chemotherapy +/- Selective internal radiation therapy as first-line treatment for patients with metastatic colorectal cancer

Author keywords

Colorectal neoplasms; Liver; Meta analysis; Neoplasm metastasis; Radiation oncology; Survival analysis

Indexed keywords


EID: 85033193294     PISSN: None     EISSN: 19290748     Source Type: Journal    
DOI: 10.2196/resprot.7201     Document Type: Article
Times cited : (19)

References (27)
  • 2
    • 84860274974 scopus 로고    scopus 로고
    • Ten-year survival after liver resection for colorectal metastases: systematic review and meta-analysis
    • [FREE Full text] [doi] [Medline: 22091431]
    • Abbas S, Lam V, Hollands M. Ten-year survival after liver resection for colorectal metastases: systematic review and meta-analysis. ISRN Oncol 2011 [FREE Full text] [doi: 10.5402/2011/763245] [Medline: 22091431]
    • (2011) ISRN Oncol
    • Abbas, S1    Lam, V2    Hollands, M.3
  • 3
    • 84896857705 scopus 로고    scopus 로고
    • Cause of death from liver metastases in colorectal cancer
    • Feb; [doi] [Medline: 24081807]
    • Helling TS, Martin M. Cause of death from liver metastases in colorectal cancer. Ann Surg Oncol 2014 Feb;21(2):501-506. [doi: 10.1245/s10434-013-3297-7] [Medline: 24081807]
    • (2014) Ann Surg Oncol , vol.21 , Issue.2 , pp. 501-506
    • Helling, TS1    Martin, M.2
  • 4
    • 21344459502 scopus 로고    scopus 로고
    • Treatment of liver metastases of colorectal cancer
    • Suppl 2: [FREE Full text] [doi] [Medline: 15958446]
    • Rothbarth J, van de Velde CJH. Treatment of liver metastases of colorectal cancer. Ann Oncol 2005;16 Suppl 2:ii144-ii149 [FREE Full text] [doi: 10.1093/annonc/mdi702] [Medline: 15958446]
    • (2005) Ann Oncol , vol.16 , pp. ii144-ii149
    • Rothbarth, J1    van de Velde, CJH.2
  • 5
    • 14944385383 scopus 로고    scopus 로고
    • Predictors of survival after radiofrequency thermal ablation of colorectal cancer metastases to the liver: a prospective study
    • Mar 01; [doi] [Medline: 15684312]
    • Berber E, Pelley R, Siperstein AE. Predictors of survival after radiofrequency thermal ablation of colorectal cancer metastases to the liver: a prospective study. J Clin Oncol 2005 Mar 01;23(7):1358-1364. [doi: 10.1200/JCO.2005.12.039] [Medline: 15684312]
    • (2005) J Clin Oncol , vol.23 , Issue.7 , pp. 1358-1364
    • Berber, E1    Pelley, R2    Siperstein, AE.3
  • 6
    • 26944479618 scopus 로고    scopus 로고
    • Short- and long-term results of intraoperative radiofrequency ablation of liver metastases
    • Nov; [doi] [Medline: 15864606]
    • Navarra G, Ayav A, Weber J, Jensen SL, Smadga C, Nicholls JP, et al. Short- and long-term results of intraoperative radiofrequency ablation of liver metastases. Int J Colorectal Dis 2005 Nov;20(6):521-528. [doi: 10.1007/s00384-005-0743-4] [Medline: 15864606]
    • (2005) Int J Colorectal Dis , vol.20 , Issue.6 , pp. 521-528
    • Navarra, G1    Ayav, A2    Weber, J3    Jensen, SL4    Smadga, C5    Nicholls, JP6
  • 7
    • 33748101222 scopus 로고    scopus 로고
    • Towards a pan-European consensus on the treatment of patients with colorectal liver metastases
    • European Colorectal Metastases Treatment Group. Sep; [doi] [Medline: 16904315]
    • Van Cutsem E, Nordlinger B, Adam R, Köhne C, Pozzo C, Poston G, European Colorectal Metastases Treatment Group. Towards a pan-European consensus on the treatment of patients with colorectal liver metastases. Eur J Cancer 2006 Sep;42(14):2212-2221. [doi: 10.1016/j.ejca.2006.04.012] [Medline: 16904315]
    • (2006) Eur J Cancer , vol.42 , Issue.14 , pp. 2212-2221
    • Van Cutsem, E1    Nordlinger, B2    Adam, R3    Köhne, C4    Pozzo, C5    Poston, G6
  • 8
    • 85009989754 scopus 로고    scopus 로고
    • Resection of liver metastases in colorectal cancer in the era of expanding systemic therapy
    • Sep 28. [doi] [Medline: 27686016]
    • Jones RP, Poston GJ. Resection of liver metastases in colorectal cancer in the era of expanding systemic therapy. Annu Rev Med 2016 Sep 28. [doi: 10.1146/annurev-med-062415-093510] [Medline: 27686016]
    • (2016) Annu Rev Med
    • Jones, RP1    Poston, GJ.2
  • 9
    • 33644819672 scopus 로고    scopus 로고
    • Oxaliplatin, fluorouracil, and leucovorin for patients with unresectable liver-only metastases from colorectal cancer: a North Central Cancer Treatment Group phase II study
    • Dec 20; [doi] [Medline: 16230673]
    • Alberts SR, Horvath WL, Sternfeld WC, Goldberg RM, Mahoney MR, Dakhil SR, et al. Oxaliplatin, fluorouracil, and leucovorin for patients with unresectable liver-only metastases from colorectal cancer: a North Central Cancer Treatment Group phase II study. J Clin Oncol 2005 Dec 20;23(36):9243-9249. [doi: 10.1200/JCO.2005.07.740] [Medline: 16230673]
    • (2005) J Clin Oncol , vol.23 , Issue.36 , pp. 9243-9249
    • Alberts, SR1    Horvath, WL2    Sternfeld, WC3    Goldberg, RM4    Mahoney, MR5    Dakhil, SR6
  • 10
    • 23844448040 scopus 로고    scopus 로고
    • Neoadjuvant treatment of unresectable colorectal liver metastases: correlation between tumour response and resection rates
    • Aug; [FREE Full text] [doi] [Medline: 15870084]
    • Folprecht G, Grothey A, Alberts S, Raab H, Köhne C. Neoadjuvant treatment of unresectable colorectal liver metastases: correlation between tumour response and resection rates. Ann Oncol 2005 Aug;16(8):1311-1319 [FREE Full text] [doi: 10.1093/annonc/mdi246] [Medline: 15870084]
    • (2005) Ann Oncol , vol.16 , Issue.8 , pp. 1311-1319
    • Folprecht, G1    Grothey, A2    Alberts, S3    Raab, H4    Köhne, C.5
  • 11
    • 75649083860 scopus 로고    scopus 로고
    • Liver metastases from colorectal cancer: radioembolization with systemic therapy
    • Dec; [doi] [Medline: 19884901]
    • Nicolay NH, Berry DP, Sharma RA. Liver metastases from colorectal cancer: radioembolization with systemic therapy. Nat Rev Clin Oncol 2009 Dec;6(12):687-697. [doi: 10.1038/nrclinonc.2009.165] [Medline: 19884901]
    • (2009) Nat Rev Clin Oncol , vol.6 , Issue.12 , pp. 687-697
    • Nicolay, NH1    Berry, DP2    Sharma, RA.3
  • 12
    • 84874653883 scopus 로고    scopus 로고
    • Anatomical basis and histopathological changes resulting from selective internal radiotherapy for liver metastases
    • Mar; [FREE Full text] [doi] [Medline: 23162108]
    • Wang LM, Jani AR, Hill EJ, Sharma RA. Anatomical basis and histopathological changes resulting from selective internal radiotherapy for liver metastases. J Clin Pathol 2013 Mar;66(3):205-211 [FREE Full text] [doi: 10.1136/jclinpath-2012-201231] [Medline: 23162108]
    • (2013) J Clin Pathol , vol.66 , Issue.3 , pp. 205-211
    • Wang, LM1    Jani, AR2    Hill, EJ3    Sharma, RA.4
  • 13
    • 84903856363 scopus 로고    scopus 로고
    • FOXFIRE protocol: an open-label, randomised, phase III trial of 5-fluorouracil, oxaliplatin and folinic acid (OxMdG) with or without interventional Selective Internal Radiation Therapy (SIRT) as first-line treatment for patients with unresectable liver-only or liver-dominant metastatic colorectal cancer
    • FOXFIRE Protocol Development Group and the NCRI Colorectal Clinical Study Group. Jul 09;: [FREE Full text] [doi] [Medline: 25011439]
    • Dutton SJ, Kenealy N, Love SB, Wasan HS, Sharma RA, FOXFIRE Protocol Development Group and the NCRI Colorectal Clinical Study Group. FOXFIRE protocol: an open-label, randomised, phase III trial of 5-fluorouracil, oxaliplatin and folinic acid (OxMdG) with or without interventional Selective Internal Radiation Therapy (SIRT) as first-line treatment for patients with unresectable liver-only or liver-dominant metastatic colorectal cancer. BMC Cancer 2014 Jul 09;14:497 [FREE Full text] [doi: 10.1186/1471-2407-14-497] [Medline: 25011439]
    • (2014) BMC Cancer , vol.14 , pp. 497
    • Dutton, SJ1    Kenealy, N2    Love, SB3    Wasan, HS4    Sharma, RA5
  • 14
    • 84924414313 scopus 로고    scopus 로고
    • Selective Internal Radiation Therapy (SIRT) with yttrium-90 resin microspheres plus standard systemic chemotherapy regimen of FOLFOX versus FOLFOX alone as first-line treatment of non-resectable liver metastases from colorectal cancer: the SIRFLOX study
    • Dec 01;: [FREE Full text] [doi] [Medline: 25487708]
    • Gibbs P, Gebski V, Van Buskirk M, Thurston K, Cade DN, Van Hazel GA. Selective Internal Radiation Therapy (SIRT) with yttrium-90 resin microspheres plus standard systemic chemotherapy regimen of FOLFOX versus FOLFOX alone as first-line treatment of non-resectable liver metastases from colorectal cancer: the SIRFLOX study. BMC Cancer 2014 Dec 01;14:897 [FREE Full text] [doi: 10.1186/1471-2407-14-897] [Medline: 25487708]
    • (2014) BMC Cancer , vol.14 , pp. 897
    • Gibbs, P1    Gebski, V2    Van Buskirk, M3    Thurston, K4    Cade, DN5    Van Hazel, GA.6
  • 15
    • 84969513763 scopus 로고    scopus 로고
    • SIRFLOX: randomized phase III trial comparing first-line mFOLFOX6 (plus or minus bevacizumab) versus mFOLFOX6 (plus or minus bevacizumab) plus selective internal radiation therapy in patients with metastatic colorectal cancer
    • May 20; [doi] [Medline: 26903575]
    • van Hazel GA, Heinemann V, Sharma NK, Findlay MPN, Ricke J, Peeters M, et al. SIRFLOX: randomized phase III trial comparing first-line mFOLFOX6 (plus or minus bevacizumab) versus mFOLFOX6 (plus or minus bevacizumab) plus selective internal radiation therapy in patients with metastatic colorectal cancer. J Clin Oncol 2016 May 20;34(15):1723-1731. [doi: 10.1200/JCO.2015.66.1181] [Medline: 26903575]
    • (2016) J Clin Oncol , vol.34 , Issue.15 , pp. 1723-1731
    • van Hazel, GA1    Heinemann, V2    Sharma, NK3    Findlay, MPN4    Ricke, J5    Peeters, M6
  • 16
    • 0035700227 scopus 로고    scopus 로고
    • Randomised trial of SIR-Spheres plus chemotherapy versus chemotherapy alone for treating patients with liver metastases from primary large bowel cancer
    • Dec; [FREE Full text] [Medline: 11843249]
    • Gray B, Van Hazel G, Hope M, Burton M, Moroz P, Anderson J, et al. Randomised trial of SIR-Spheres plus chemotherapy versus chemotherapy alone for treating patients with liver metastases from primary large bowel cancer. Ann Oncol 2001 Dec;12(12):1711-1720 [FREE Full text] [Medline: 11843249]
    • (2001) Ann Oncol , vol.12 , Issue.12 , pp. 1711-1720
    • Gray, B1    Van Hazel, G2    Hope, M3    Burton, M4    Moroz, P5    Anderson, J6
  • 17
    • 34250650940 scopus 로고    scopus 로고
    • Oxaliplatin/fluorouracil/leucovorin (FOLFOX4 and modified FOLFOX6) in patients with refractory or advanced colorectal cancer: post-approval Japanese population experience
    • Jun; [doi] [Medline: 17566846]
    • Shimizu T, Satoh T, Tamura K, Ozaki T, Okamoto I, Fukuoka M, et al. Oxaliplatin/fluorouracil/leucovorin (FOLFOX4 and modified FOLFOX6) in patients with refractory or advanced colorectal cancer: post-approval Japanese population experience. Int J Clin Oncol 2007 Jun;12(3):218-223. [doi: 10.1007/s10147-007-0658-x] [Medline: 17566846]
    • (2007) Int J Clin Oncol , vol.12 , Issue.3 , pp. 218-223
    • Shimizu, T1    Satoh, T2    Tamura, K3    Ozaki, T4    Okamoto, I5    Fukuoka, M6
  • 18
    • 0242266500 scopus 로고    scopus 로고
    • Modified de Gramont with oxaliplatin in the first-line treatment of advanced colorectal cancer
    • Oct 06; [FREE Full text] [doi] [Medline: 14520437]
    • Braun MS, Adab F, Bradley C, McAdam K, Thomas G, Wadd NJ, et al. Modified de Gramont with oxaliplatin in the first-line treatment of advanced colorectal cancer. Br J Cancer 2003 Oct 06;89(7):1155-1158 [FREE Full text] [doi: 10.1038/sj.bjc.6601237] [Medline: 14520437]
    • (2003) Br J Cancer , vol.89 , Issue.7 , pp. 1155-1158
    • Braun, MS1    Adab, F2    Bradley, C3    McAdam, K4    Thomas, G5    Wadd, NJ6
  • 19
    • 79551521053 scopus 로고    scopus 로고
    • Phase III trial assessing bevacizumab in stages II and III carcinoma of the colon: results of NSABP protocol C-08
    • Jan 01; [FREE Full text] [doi] [Medline: 20940184]
    • Allegra CJ, Yothers G, O'Connell MJ, Sharif S, Petrelli NJ, Colangelo LH, et al. Phase III trial assessing bevacizumab in stages II and III carcinoma of the colon: results of NSABP protocol C-08. J Clin Oncol 2011 Jan 01;29(1):11-16 [FREE Full text] [doi: 10.1200/JCO.2010.30.0855] [Medline: 20940184]
    • (2011) J Clin Oncol , vol.29 , Issue.1 , pp. 11-16
    • Allegra, CJ1    Yothers, G2    O'Connell, MJ3    Sharif, S4    Petrelli, NJ5    Colangelo, LH6
  • 20
    • 84872182798 scopus 로고    scopus 로고
    • Systemic cytotoxic and biologic therapies for colorectal cancer liver metastases: expert consensus statement
    • Feb; [FREE Full text] [doi] [Medline: 23297722]
    • Clary BM, Grothey A, Kopetz S, Marsh RDW. Systemic cytotoxic and biologic therapies for colorectal cancer liver metastases: expert consensus statement. HPB (Oxford) 2013 Feb;15(2):116-118 [FREE Full text] [doi: 10.1111/j.1477-2574.2012.00598.x] [Medline: 23297722]
    • (2013) HPB (Oxford) , vol.15 , Issue.2 , pp. 116-118
    • Clary, BM1    Grothey, A2    Kopetz, S3    Marsh, RDW.4
  • 21
    • 84886719568 scopus 로고    scopus 로고
    • Perioperative FOLFOX4 chemotherapy and surgery versus surgery alone for resectable liver metastases from colorectal cancer (EORTC 40983): long-term results of a randomised, controlled, phase 3 trial
    • EORTC Gastro-Intestinal Tract Cancer Group, Cancer UK, Arbeitsgruppe Lebermetastasen und tumoren in der Chirurgischen Arbeitsgemeinschaft Onkologie (ALM-CAO), Australasian Gastro-Intestinal Trials Group (AGITG), Fédération Francophone de Cancérologie Digestive (FFCD). Nov; [doi] [Medline: 24120480]
    • Nordlinger B, Sorbye H, Glimelius B, Poston GJ, Schlag PM, Rougier P, EORTC Gastro-Intestinal Tract Cancer Group, Cancer UK, Arbeitsgruppe Lebermetastasen und tumoren in der Chirurgischen Arbeitsgemeinschaft Onkologie (ALM-CAO), Australasian Gastro-Intestinal Trials Group (AGITG), Fédération Francophone de Cancérologie Digestive (FFCD). Perioperative FOLFOX4 chemotherapy and surgery versus surgery alone for resectable liver metastases from colorectal cancer (EORTC 40983): long-term results of a randomised, controlled, phase 3 trial. Lancet Oncol 2013 Nov;14(12):1208-1215. [doi: 10.1016/S1470-2045(13)70447-9] [Medline: 24120480]
    • (2013) Lancet Oncol , vol.14 , Issue.12 , pp. 1208-1215
    • Nordlinger, B1    Sorbye, H2    Glimelius, B3    Poston, GJ4    Schlag, PM5    Rougier, P6
  • 22
    • 84862026304 scopus 로고    scopus 로고
    • Addition of cetuximab to chemotherapy as first-line treatment for KRAS wild-type metastatic colorectal cancer: pooled analysis of the CRYSTAL and OPUS randomised clinical trials
    • Jul; [doi] [Medline: 22446022]
    • Bokemeyer C, Van Cutsem E, Rougier P, Ciardiello F, Heeger S, Schlichting M, et al. Addition of cetuximab to chemotherapy as first-line treatment for KRAS wild-type metastatic colorectal cancer: pooled analysis of the CRYSTAL and OPUS randomised clinical trials. Eur J Cancer 2012 Jul;48(10):1466-1475. [doi: 10.1016/j.ejca.2012.02.057] [Medline: 22446022]
    • (2012) Eur J Cancer , vol.48 , Issue.10 , pp. 1466-1475
    • Bokemeyer, C1    Van Cutsem, E2    Rougier, P3    Ciardiello, F4    Heeger, S5    Schlichting, M6
  • 23
    • 84864129583 scopus 로고    scopus 로고
    • Radiofrequency ablation combined with systemic treatment versus systemic treatment alone in patients with non-resectable colorectal liver metastases: a randomized EORTC Intergroup phase II study (EORTC 40004)
    • EORTC Gastro-Intestinal Tract Cancer Group, Arbeitsgruppe Lebermetastasen und tumoren in der Chirurgischen Arbeitsgemeinschaft Onkologie (ALM-CAO), National Cancer Research Institute Colorectal Clinical Study Group (NCRI CCSG). Oct; [FREE Full text] [doi] [Medline: 22431703]
    • Ruers T, Punt C, Van Coevorden F, Pierie JPEN, Borel-Rinkes I, Ledermann JA, EORTC Gastro-Intestinal Tract Cancer Group, Arbeitsgruppe Lebermetastasen und tumoren in der Chirurgischen Arbeitsgemeinschaft Onkologie (ALM-CAO), National Cancer Research Institute Colorectal Clinical Study Group (NCRI CCSG). Radiofrequency ablation combined with systemic treatment versus systemic treatment alone in patients with non-resectable colorectal liver metastases: a randomized EORTC Intergroup phase II study (EORTC 40004). Ann Oncol 2012 Oct;23(10):2619-2626 [FREE Full text] [doi: 10.1093/annonc/mds053] [Medline: 22431703]
    • (2012) Ann Oncol , vol.23 , Issue.10 , pp. 2619-2626
    • Ruers, T1    Punt, C2    Van Coevorden, F3    Pierie, JPEN4    Borel-Rinkes, I5    Ledermann, JA6
  • 24
    • 84956721089 scopus 로고    scopus 로고
    • Radiofrequency ablation (RFA) combined with chemotherapy for unresectable colorectal liver metastases (CRC LM): Long-term survival results of a randomized phase II study of the EORTC-NCRI CCSG-ALM Intergroup 40004 (CLOCC)
    • (Suppl)
    • Ruers T, Cornelis J, Punt C, Van Coevorden F, Pierie J, Rinkes I, et al. Radiofrequency ablation (RFA) combined with chemotherapy for unresectable colorectal liver metastases (CRC LM): Long-term survival results of a randomized phase II study of the EORTC-NCRI CCSG-ALM Intergroup 40004 (CLOCC). J Clin Oncol 2015;33(Suppl):A3501.
    • (2015) J Clin Oncol , vol.33 , pp. A3501
    • Ruers, T1    Cornelis, J2    Punt, C3    Van Coevorden, F4    Pierie, J5    Rinkes, I6
  • 25
    • 84938702916 scopus 로고    scopus 로고
    • Individual participant data (IPD) meta-analyses of randomised controlled trials: guidance on their use
    • Jul; [FREE Full text] [doi] [Medline: 26196287]
    • Tierney JF, Vale C, Riley R, Smith CT, Stewart L, Clarke M, et al. Individual participant data (IPD) meta-analyses of randomised controlled trials: guidance on their use. PLoS Med 2015 Jul;12(7):e1001855 [FREE Full text] [doi: 10.1371/journal.pmed.1001855] [Medline: 26196287]
    • (2015) PLoS Med , vol.12 , Issue.7 , pp. e1001855
    • Tierney, JF1    Vale, C2    Riley, R3    Smith, CT4    Stewart, L5    Clarke, M6
  • 26
    • 84876028745 scopus 로고    scopus 로고
    • Individual participant data meta-analysis for a binary outcome: one-stage or two-stage?
    • [FREE Full text] [doi] [Medline: 23585842]
    • Debray TPA, Moons KGM, Abo-Zaid GMA, Koffijberg H, Riley RD. Individual participant data meta-analysis for a binary outcome: one-stage or two-stage? PLoS One 2013;8(4):e60650 [FREE Full text] [doi: 10.1371/journal.pone.0060650] [Medline: 23585842]
    • (2013) PLoS One , vol.8 , Issue.4 , pp. e60650
    • Debray, TPA1    Moons, KGM2    Abo-Zaid, GMA3    Koffijberg, H4    Riley, RD.5
  • 27
    • 84867036811 scopus 로고    scopus 로고
    • Statistical analysis of individual participant data meta-analyses: a comparison of methods and recommendations for practice
    • [FREE Full text] [doi] [Medline: 23056232]
    • Stewart GB, Altman DG, Askie LM, Duley L, Simmonds MC, Stewart LA. Statistical analysis of individual participant data meta-analyses: a comparison of methods and recommendations for practice. PLoS One 2012;7(10):e46042 [FREE Full text] [doi: 10.1371/journal.pone.0046042] [Medline: 23056232]
    • (2012) PLoS One , vol.7 , Issue.10 , pp. e46042
    • Stewart, GB1    Altman, DG2    Askie, LM3    Duley, L4    Simmonds, MC5    Stewart, LA.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.