Preparation, characterization and in vivo evaluation of pH sensitive, safe quercetin-succinylated chitosan-alginate core-shell-corona nanoparticle for diabetes treatment

Carbohydrate Polymers

Volumn 182, Issue , 2018, Pages 42-51

  Mukhopadhyay, Piyasi ^a   Maity, Subhajit ^b   Mandal, Sudipto ^d   Chakraborti, Abhay Sankar ^b   Prajapati, A K ^a   Kundu, P P ^b,c  

^a M S UNIVERSITY OF BARODA   (India)

^b UNIVERSITY OF CALCUTTA   (India)

^c INDIAN INSTITUTE OF TECHNOLOGY ROORKEE   (India)

^d NICED   (India)

Author keywords

Alginate; Core shell nanoparticles; Diabetes treatment; Quercetin delivery; Succinyl chitosan

Indexed keywords

ALGINATE; CHITIN; CHITOSAN; NANOPARTICLES; PARTICLE SIZE; PH SENSORS; PHENOLS; SHELLS (STRUCTURES);

CHITOSAN ALGINATES; CORE-SHELL NANOPARTICLES; DRUG ENTRAPMENT; GLUCOSE HOMEOSTASIS; IONIC CROSS LINKING; LOADING EFFICIENCY; POLYMERIC CARRIERS; QUERCETIN DELIVERY;

FLAVONOIDS;

ALGINIC ACID; ANTIDIABETIC AGENT; CHITOSAN; DRUG CARRIER; GLUCURONIC ACID; HEXURONIC ACID; NANOPARTICLE; QUERCETIN; SUCCINIC ACID;

ANIMAL; CHEMISTRY; DRUG DELIVERY SYSTEM; EXPERIMENTAL DIABETES MELLITUS; HT-29 CELL LINE; HUMAN; MALE; ORAL DRUG ADMINISTRATION; PARTICLE SIZE; PH; RAT; WISTAR RAT;

ADMINISTRATION, ORAL; ALGINATES; ANIMALS; CHITOSAN; DIABETES MELLITUS, EXPERIMENTAL; DRUG CARRIERS; DRUG DELIVERY SYSTEMS; GLUCURONIC ACID; HEXURONIC ACIDS; HT29 CELLS; HUMANS; HYDROGEN-ION CONCENTRATION; HYPOGLYCEMIC AGENTS; MALE; NANOPARTICLES; PARTICLE SIZE; QUERCETIN; RATS; RATS, WISTAR; SUCCINIC ACID;

EID: 85032840150     PISSN: 01448617     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.carbpol.2017.10.098     Document Type: Article

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